A density-independent rigidity transition in biological tissues

Bi, Dapeng, Lopez, J. H., Schwarz, J. M., Manning, M. Lisa·2015·Nature Physics
DOI 10.1038/nphys3471

Cited by (786)

Items 401–500 of 786

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  10. Evidence for Anomalous Dynamic Heterogeneities in Isostatic Supercooled Liquids
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  16. Coordination of contractile tension and cell area changes in an epithelial cell monolayer
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  19. Finite elasticity of the vertex model and its role in rigidity of curved cellular tissues
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  24. Learning Collective Cell Migratory Dynamics from a Static Snapshot with Graph Neural Networks
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  27. Nonequilibrium dynamics of isostatic spring networks
    Federico S. Gnesotto, Benedikt Remlein, Chase P. Broedersz · 2019 · Physical review. E
  28. Overcrowding drives the unjamming transition of gap-free monolayers
    Su, Tao, Ganhui Lan · 2016 · arXiv (Cornell University)
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  30. Shape-driven confluent rigidity transition in curved biological tissues
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  31. Coarse-graining the vertex model and its response to shear
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