It takes two to tango: NAD(+) and sirtuins in aging/longevity control

Cited by (395)

Items 301–395 of 395

1. Dietary Activation of AMP-Activated Protein Kinase (AMPK) to Treat Insulin Resistance
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2. Loss-of-function approach using mouse retinal explants showed pivotal roles of Nmnat2 in early and middle stages of retinal development
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3. Chemistry of the Joint Origin and Evolution of Life, Death, and Aging
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4. Resveratrol mitigates oxidative stress and suppresses HBV replication via modulation of the SIRT1-Nrf2 pathway in liver cells
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5. The caloric restriction fallacy, rodent diet aids and the tumor suppression theory of aging
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6. Longevity Bottlenecks
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7. Age-Dependent Changes in Taurine, Serine, and Methionine Release in the Frontal Cortex of Awake Freely-Moving Rats: A Microdialysis Study
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8. Decoding human longevity: Genetic and molecular insights from accelerated to successful ageing
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9. Mechanisms of NAD+ Homeostasis in Aging and Disease
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10. Oxidation of biological molecules with age and induced oxidative stress in different growth phases of Saccharomyces cerevisiae
    Madhumathan Mukherjee, Chandan Kumar Jana, N. K. Das · 2023 · Antonie van Leeuwenhoek
11. Network Analysis Reveals the Molecular Bases of Statin Pleiotropy That Vary with Genetic Background
    Cintya E. del Rio Hernandez, Lani J. Campbell, Paul H. Atkinson, Andrew B. Munkacsi · 2023 · Microbiology Spectrum
12. Healthy Aging and Epigenetic Drugs for Diabetes and Obesity
    Sunitha Meruvu, John D. Bowman, Mahua Choudhury · 2017 · Elsevier eBooks
13. Sirtuins and aging
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14. Accounting for NAD Concentrations in Genome-Scale Metabolic Models Captures Important Metabolic Alterations in NAD-Depleted Systems
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15. The Basics of Biogerontology
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16. Sirtuin Inhibitors and Activators
    Minna Rahnasto‐Rilla, Jonna Tyni, Maija K. Lahtela-Kakkonen · 2019 · Topics in medicinal chemistry
17. Bacterial sirtuin CobB and PRPP synthase crosstalk in the regulation of protein acetylation in Escherichia coli
    Beata Maria Walter, Joanna Morcinek-Orłowska, Aneta Szulc, Andrew L. Lovering, James R. J. Haycocks, Manuel Banzhaf, Monika Katarzyna Glinkowska · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
18. Atherosclerosis is attenuated by acacetin via Sirt1-mediated activation of AMPK/Sirt3 signals in diabetic ApoE-/- mice
    Wei-Min Han, Xu-Chang Chen, Yan Wang, Gui‐Rong Li · 2020
19. Randomized Crossover Clinical Trial of Nicotinamide Riboside and Coenzyme Q10 on Metabolic Health and Mitochondrial Bioenergetics in CKD
    Armin Ahmadi, Ana P. Valencia, Gwénaëlle Begue, Jennifer Norman, Sili Fan, Blythe P Durbin-Johnson, Bradley N. Jenner, Matthew D. Campbell, Gustavo Reyes, Pankaj Kapahi et al. · 2024 · medRxiv
20. Circadian Control of Mitochondrial Dynamics and Its Implication in Aging
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21. Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT
    Bowei Li, Zhongyun Xie, Mengmeng Wang, Shuke Nie, Zhengjiang Qian, Xin Meng, Xia Liu, Seong Su Kang, Keqiang Ye · 2025 · Advanced Science
22. Sirtuins modulators mitigate hypoxia-induced cell death due to changes in histone 3 acetylation, and mitochondrial function, dynamics, and content
    Luiz Silva, Amanda Siena, Jéssica Mayumi Camargo Yuzawa, Tatiana Rosado Rosenstock · 2025 · Neuropharmacology
23. Multivalent cannabinoid epigenotoxicities and multigenerational aging
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24. Endogenous and exogenous viral reactivation as a driver of epigenetic drift and mitophagy failure in aging
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25. Beta-Hydroxybutyrate but not NMN supplementation mimics caloric restriction reducing early mortality in Daphnia
    A. Catherine Pearson, Lev Y. Yampolsky · 2025 · Biogerontology
26. The effect of obesity and aging on NAD+/Sirtuin metabolism transcription and DNA methylation in subcutaneous adipose tissue of monozygotic twin pairs discordant for BMI
    Helena A. K. Lapatto, Birgitta W. van der Kolk, Maheswary Muniandy, Sini Heinonen, Aino Heikkinen, Marcus Alvarez, Seung Hyuk Lee, Riikka Jokinen, Jesper Lundbom, Juho Kuula et al. · 2026 · International Journal of Obesity
27. Circulating eNAMPT in Glaucoma: A Semi-Quantitative Plasma Analysis Before and After Nicotinamide Supplementation
    Antoni Vallbona-Garcia, Simon T. Gustavsson, Theo G. M. F. Gorgels, James R. Tribble, Carroll A.B. Webers, Hubert J.M. Smeets, Gauti Jóhannesson, Pete A. Williams, Birke J. Benedikter · 2026 · Translational Vision Science & Technology
28. Integrative systems biology identifies SIRT1 as a senescence-related theranostic target in atherosclerosis and poliumoside as a natural activator
    Xiaolong Wang, Runlu Shi, Chen Ji, Huilin Li, Ziwen Jia, Xin Tian, Xi Xie, Yanping WANG, Qiao-Ping Wang · 2026 · Frontiers in Pharmacology
29. Skin Cancer Prevention and Antiaging: Role of Nicotinamide
    Francesco Moro, Annarita Panebianco, Valeria Bartolocci, Alessio Capone, Antonio Di Guardo, Mariafrancesca Hyeraci, Giuseppe Paolo Antonio Gemma, Giovanni Di Lella, Laura Colonna, Francesco Ricci et al. · 2026 · International Journal of Molecular Sciences
30. The Temporal Architecture of Human Cells: Organelle Clocks and Distributed Circadian Time
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31. Pyrroloquinoline Quinone Targets the Allosteric Activation Site of Nicotinamide Phosphoribosyltransferase (NAMPT): Structural Basis and Consequences for NAD+ Metabolism in Aging
    Alessandro Medoro, Sergio Davinelli, Tassadaq Hussain Jafar, Truong Tan Trung, Ciro Costagliola, Gemma Caterina Maria Rossi, Giovanni Scapagnini · 2026 · Applied Sciences
32. A Budding Topic
    Jessica T. Smith, Brandt L. Schneider · 2018 · Elsevier eBooks
33. Potential mechanisms of exercise in maintaining skin homeostasis disrupted by protein deficiency (Review)
    Faysal Kastella, Vita Murniati Tarawan, Iwan Setiawan, Decky Gunawan, Diana Krisanti Jasaputra, Hanna Goenawan, Julia Windi Gunadi, Ronny Lesmana · 2024 · World Academy of Sciences Journal
34. Computational model of circadian oscillator in mammals: Interaction with NAD+/SIRT1 system and age-related changes in the expression of circadian oscillator genes
    N. L. Podkolodnyy, Natalya N. Tverdokhleb, Olga A. Podkolodnaya · 2017 · Russian Journal of Genetics Applied Research
35. Vascular diseases
    Goro Katsuumi, Tohru Minamino · 2021 · Elsevier eBooks
36. The Biological Basis of Aging
    Junko Oshima, Fuki Marie Hisama, George M. Martin · 2019 · Elsevier eBooks
37. Circadian Clock, Epigenetic Regulators (Sirtuins), and Metabolism
    Mirella L. Meyer‐Ficca, Ralph G. Meyer · 2018 · Elsevier eBooks
38. Geroscience
    Brian Keith Kennedy, Jorming Goh, Esther S.P. Wong · 2021 · Springer eBooks
39. Recruitment of CTCF to the SIRT1 promoter after Oxidative Stress mediates Cardioprotective Transcription
    T Wagner, Priyanka Priyanka, Rudi Micheletti, Meyer J. Friedman, Sreejith J. Nair, Amir Gamliel, Havilah Taylor, Xiaoyuan Song, Miook Cho, Soohwan Oh et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
40. Multi-modal, Label-free, Optical Mapping of Cellular Metabolic Function and Oxidative Stress in 3D Engineered Brain Tissue Models
    Yang Zhang, Maria G. Savvidou, Volha Liaudanskaya, Varshini Ramanathan, Thi Tho Bui, Matthew Lindley, Ash Sze, Ugochukwu O. Ugwu, Yuhang Fu, Matthew E. Dilsizian et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
41. Causally-anchored multi-omic deep learning recovers exercise-responsive and ageing-causal genes from human physical activity
    Ciara Gallardo Juan, Lazaros Ntasis · 2026 · medRxiv
42. Nicotinamide Riboside Enhances Mitochondrial Bioenergetics and Dopaminergic Signaling Independent of Neuron Survival in a Double-Hit Parkinson’s Model
    Sukanya Saha, Chengbo Meng, Jie Dong, Jingheng Zhou, Sunny Wang, Amy B. Papaneri, Lixin Sun, Huaibin Cai, Guohong Cui · 2026 · Research Square
43. NAD + Modulation
    Elena Katsyuba, Johan H. Auwerx · 2018 · Elsevier eBooks
44. Thoughts About Health Span
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45. Tópicos em Ciências da Saúde Volume 6
    Sandyerlly da Paz do Nascimento, Rhayra Priscilla Moraes Nóbrega, Ludmyla Albuquerque Santos de Souza, Felipe Lima Soares, Kátia Rau de Almeida Callou, Ana Paula Moraes Ventura, Jailton Rocha Misael, Cláudio José dos Santos Júnior, Ilma Falcão Silva, Gilvana Maria Vieira Xavier et al. · 2019
46. Environments, resources, and health
    Moyra Smith · 2020 · Elsevier eBooks
47. Taming the Pro-Aging Factors and Pathways For Longevity and Improving Health-span
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48. Impacto da hospitalização na capacidade funcional de idosos
    Felipe Lima Rebêlo, Victor de Andrade Vieira, Brenda Karolyne dos Santos Souza, Alessandra Myrella Braz da Silva, Vinícius Ramon da Silva Santos, Catarina Maria Leite de Abreu · 2019
49. Sirtuins in Aging
    Brian J. Morris · 2019 · Springer eBooks
50. MCART1 is required for mitochondrial NAD transport
    Nora Kory, Jelmi uit de Bos, Sanne van der Rijt, Nevena Jankovic, Miriam A. Güra, Nicholas L. Arp, Izabella Agostinho Pena, Gyan Prakash, Sze Ham Chan, Tenzin Kunchok et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
51. Stronger Educational Performance in Early Life Correlates with Higher Cancer Risk, Lower Dementia Risk and Lower All-cause Mortality in Later Life – but Why?
    Anatoly L. Mayburd · 2021 · Research Square
52. Prevention and Treatment of the Troubles of the Elderly
    Giacinto Libertini, Graziamaria Corbi, Valeria Conti, Olga S. Shubernetskaya, Nicola Ferrara · 2021 · Advances in studies of aging and health
53. Sirtuins in Aging
    Brian J. Morris · 2021 · Springer eBooks
54. Stimulating the sir2-pgc-1ɑ axis rescues exercise capacity and mitochondrial respiration in Drosophila tafazzin mutants
    Deena Damschroder, Ruben Zapata Perez, Riekelt H. Houtkooper, Robert J. Wessells · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
55. Calorie Restriction Mimetics
    Donald K. Ingram · 2018 · Elsevier eBooks
56. Faculty Opinions recommendation of The Systems Biology of Single-Cell Aging.
    Björn Schumacher · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
57. Geroscience
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58. Faculty Opinions recommendation of Mitonuclear genomics and aging.
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59. The Mechanism of Decline of Senescent Skeletal Muscle Satellite Cell Self-Renewal and Regenerative Proliferation: The Role of Heparan Sulfate-FGF-2--FGFR1-p38αMAPK Axis, Sprouty1, miR-1, miR-133 and miR-29a
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60. Disrupted cellular quality control mechanisms in aging
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61. Mixed Models Quantify Annual Volume Change; Linear Regression Determines Thalamic Volume as the Best Subcortical Structure Volume Predictor in Alzheimer’s Disease and Aging
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62. Papel da Sirtuina 1 na ativação e diferenciação das células T CD4>sup<+>/sup< em um modelo murino de obesidade e transplante
    Omar Alberto Domínguez-Amorocho · 2022 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
63. Bacteria-induced activation of a fungal silent gene cluster is controlled by histone deacetylase Sirtuin E
    Nils Jäger, Maira Rosin, Maria Cristina Stroe, Axel A. Brakhage, Thorsten Heinzel · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
64. Utilising Genetic Interaction Networks to Elucidate the Anticancer and Diabetogenic Activities
    Centya del Rio Hernandez · 2024 · Open Access Victoria University of Wellington | Te Herenga Waka (Figshare)
65. Sirtuins and the Twelve Hallmarks of Ageing: A Framework for Understanding Ageing Processes and Targeted Intervention
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66. Nicotinamide Adenine Dinucleotide and Alzheimer’s Disease
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67. Beta-Hydroxybutyrate but not NMN supplementation mimics caloric restriction reducing early mortality in Daphnia
    A. Catherine Pearson, Lev Y. Yampolsky · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
68. Epigenetic effects of Nosustrophine in Alzheimer’s disease
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69. Geospatiotemporal and causal inferential epidemiological survey and exploration of cannabinoid- and substance-related carcinogenesis in USA 2003–2017
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70. Insights into the multifaceted roles of dietary proteins in aging: Evidence from Caenorhabditis elegans and macrophage models
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71. Circadian clock: Epigenetic regulators (sirtuins), metabolism, and diseases
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72. Sirtuins, Autophagy, and Brain Longevity
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73. Neuroprotective effects of salidroside against cerebral ischemia-reperfusion injury involve downregulation of total NAMPT and suppression of microglial inflammation
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74. Heterochromatin dynamics upon release from stationary phase in budding yeast
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75. Metabolic Roles of Acyl Coenzyme A-Binding Protein (ACBP)/Diazepam Binding Inhibitor (DBI)
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78. Metabolic therapeutic targets in Alzheimer’s disease
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84. Ethical and clinical implications of sirtuin therapies
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85. NAD⁺ biology and supplementation: From mechanisms to clinical perspectives
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86. Nicotinamide Adenine Dinucleotide as a Potential Biomarker for Graft Viability During Normothermic Machine Perfusion: An Ex Vivo Rodent Study
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95. BindingDB Entry 50018259: Emerging Therapeutic Potential of SIRT6 Modulators.
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