New frontiers in translational control of the cancer genome

Truitt, Morgan L., Ruggero, Davide·2016·Nature Reviews Cancer

DOI 10.1038/nrc.2016.27

Cited by (388)

Items 101–200 of 388

Threonine fuels glioblastoma through YRDC-mediated codon-biased translational reprogramming
Xujia Wu, Huairui Yuan, Qiulian Wu, Yixin Gao, Tingting Duan, Kailin Yang, Tengfei Huang, Shuai Wang, Fanen Yuan, Derrick Lee et al. · 2024 · Nature Cancer
Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance
Moiez Ali, Erin Kaltenbrun, Grace R. Anderson, Sarah Jo Stephens, Sabrina Arena, Alberto Bardelli, Christopher M. Counter, Kris C. Wood · 2017 · Nature Communications
An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus
Albertas Navickas, Hosseinali Asgharian, Juliane Winkler, Lisa Fish, Kristle Garcia, Daniel Markett, Martin Dodel, Bruce Culbertson, Sohit Miglani, Tanvi V. Joshi et al. · 2023 · Nature Cell Biology
Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms
Christina C. Spevak, Harold Kunal Elias, Lavanya Kannan, Mohamed Ashraf Ali, Gaëlle H. Martin, Shanmugapriya Selvaraj, William S. Eng, Amanda W. Ernlund, Vinagolu K. Rajasekhar, Carolien M. Woolthuis et al. · 2020 · Cell stem cell
Breast cancer cell mesenchymal transition and metastasis directed by DAP5/eIF3d-mediated selective mRNA translation
A. Alard, Olga Katsara, Tiffany J. Rios-Fuller, Columba de la Parra, U. Ozerdem, Amanda W Ernlund, R. Schneider · 2023 · Cell Reports
eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis
Hang Ruan, Xiangyun Li, Xiang Ming Xu, Brian J. Leibowitz, Jingshan Tong, Lujia Chen, Luoquan Ao, Wei Xing, Jianhua Luo, Yanping Yu et al. · 2020 · eLife
Translational remodeling by RNA ‐binding proteins and noncoding RNAs
J.J.David Ho, Jeffrey H. S. Man, Jonathan Harry Schatz, Philip A. Marsden · 2021 · Wiley Interdisciplinary Reviews - RNA
A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer
Corina E. Antal, Tae Gyu Oh, Stefan Aigner, En‐Ching Luo, Brian A. Yee, Tania Campos, Hervé Tiriac, Katherine L. Rothamel, Cheng Zhang, Henry Jiao et al. · 2023 · Nature Communications
PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer
Jessie Hao-Ru Hsu, Benjamin Hubbell-Engler, Guillaume Adelmant, Jialiang Huang, Cailin E. Joyce, Francisca Vázquez, Barbara A. Weir, Philip G. Montgomery, Aviad Tsherniak, Andrew O. Giacomelli et al. · 2017 · Cancer Research
Highly expressed ribosomal protein L34 indicates poor prognosis in osteosarcoma and its knockdown suppresses osteosarcoma proliferation probably through translational control
Shuju Luo, Jinmin Zhao, Mitra Fowdur, Kun Wang, Tenglong Jiang, Maolin He · 2016 · Scientific Reports
The Multifaceted Role of HSF1 in Tumorigenesis
Milad J. Alasady, Marc L. Mendillo · 2020 · Advances in experimental medicine and biology
BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma
Keiji Kurata, Mehmet Samur, Priscilla Liow, Kenneth Wen, Leona Yamamoto, Jiye Liu, Eugenio Morelli, Annamaria Gullà, Yu‐Tzu Tai, Jun Qi et al. · 2023 · Clinical Cancer Research
Nutrient Control of mRNA Translation
Xin Erica Shu, Robert V. Swanda, Shu‐Bing Qian · 2020 · Annual Review of Nutrition
Oligonucleotide conjugated antibody strategies for cyclic immunostaining
Jocelyn A. Jones, Nathan P. McMahon, Ting Zheng, Jennifer R. Eng, Koei Chin, Sunjong Kwon, Michel A. Nederlof, Joe W. Gray, Summer L. Gibbs · 2021 · Scientific Reports
Protein biosynthesis, a target of sorafenib, interferes with the unfolded protein response (UPR) and ferroptosis in hepatocellular carcinoma cells
Chloé Sauzay, Christophe Louandre, Sandra Bodeau, Frédéric Anglade, Corinne Godin, Zuzana Saidak, Jean‐Xavier Fontaine, Cédric Usureau, Nathalie Martin, Roland Molinié et al. · 2018 · Oncotarget
O-GlcNAc modification of eIF4GI acts as a translational switch in heat shock response
Xingqian Zhang, Xin Erica Shu, Shu‐Bing Qian · 2018 · Nature Chemical Biology
Translating regeneration: Local protein synthesis in the neuronal injury response
Sandip Koley, Meir Rozenbaum, Mike Fainzilber, Marco Terenzio · 2018 · Neuroscience Research
Methylation of Ribosomal RNA: A Mitochondrial Perspective
Maria Isabel G. Lopez Sanchez, Miriam Cipullo, Shreekara Gopalakrishna, Anas Khawaja, Joanna Rorbach · 2020 · Frontiers in Genetics
Ribosome specialization in cancer: a spotlight on ribosomal proteins
Sofia Ramalho, Anna Dopler, William J. Faller · 2024 · NAR Cancer
Crosstalks between translation and metabolism in cancer
Stefano Biffo, Nicola Manfrini, Sara Ricciardi · 2017 · Current Opinion in Genetics & Development
Myc, Oncogenic Protein Translation, and the Role of Polyamines
Andrea T. Franson, Michael D. Hogarty · 2018 · Medical Sciences
Low level of Fibrillarin, a ribosome biogenesis factor, is a new independent marker of poor outcome in breast cancer
Flora Nguyen Van Long, Audrey Lardy-Cléaud, Dimitri Carène, Caroline Rossoni, Frédéric Catez, Paul Rollet, Nathalie Pion, Déborah Monchiet, Agathe Dolbeau, Marjorie Martin et al. · 2022 · BMC Cancer
Non-canonical mRNA translation initiation in cell stress and cancer
Mélanie Mahé, Tiffany J. Rios-Fuller, Olga Katsara, Robert J. Schneider · 2024 · NAR Cancer
Targeting Protein Synthesis in Colorectal Cancer
Stefanie Schmidt, Sarah Denk, Armin Wiegering · 2020 · Cancers
N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis
Binbin Chen, Ying Huang, Shuiqing He, Peng Yu, Lirong Wu, Hao Peng · 2023 · Cell chemical biology
Autophagy Regulation by the Translation Machinery and Its Implications in Cancer
Pilar Sarah Acevo-Rodríguez, Giovanna Maldonado, Susana Castro‐Obregón, Greco Hernández · 2020 · Frontiers in Oncology
Intricate subcellular journey of nanoparticles to the enigmatic domains of endoplasmic reticulum
Koyeli Girigoswami, Pragya Pallavi, Agnishwar Girigoswami · 2023 · Drug Delivery
2′O-Ribose Methylation of Ribosomal RNAs: Natural Diversity in Living Organisms, Biological Processes, and Diseases
Mariam Jaafar, Hermes Paraqindes, Mathieu Gabut, Jean‐Jacques Diaz, Virginie Marcel, Sébastien Durand · 2021 · Cells
Transcriptional responses to DNA damage
Silva, Erica, Ideker, Trey · 2019 · DNA repair
MYC-driven U2SURP regulates alternative splicing of SAT1 to promote triple-negative breast cancer progression
Ling Deng, Li Liao, Yinling Zhang, Shu‐Yuan Hu, Shao‐Ying Yang, Xiao-Yan Ma, Min-Ying Huang, Fang-Lin Zhang, Da‐Qiang Li · 2023 · Cancer Letters
Targeting eIF4A triggers an interferon response to synergize with chemotherapy and suppress triple-negative breast cancer
Zhao, Na, Kabotyanski, Elena B., Saltzman, Alexander B., Malovannaya, Anna, Yuan, Xueying, Reineke, Lucas C., Lieu, Nadia, Gao, Yang, Pedroza, Diego A., Calderon, Sebastian J. et al. · 2023 · Journal of Clinical Investigation
Ribosome recycling in mRNA translation, quality control, and homeostasis
Elina Nürenberg‐Goloub, Robert Tampé · 2019 · Biological Chemistry
Oligonucleotide conjugated antibodies permit highly multiplexed immunofluorescence for future use in clinical histopathology
Nathan P. McMahon, Jocelyn A. Jones, Sunjong Kwon, Koei Chin, Michel A. Nederlof, Joe W. Gray, Summer L. Gibbs · 2020 · Journal of Biomedical Optics
Inhibitors of Eukaryotic Translational Machinery as Therapeutic Agents
Angela PC Fan, Phillip P. Sharp · 2021 · Journal of Medicinal Chemistry
Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome
J.J.David Ho, Tyler Andrew Cunningham, Paola Manara, Caroline A. Coughlin, Artavazd Arumov, Evan R. Roberts, Ashanti Osteen, Preet Kumar, Daniel Bilbao, Jonathan R. Krieger et al. · 2021 · Cell Reports
Translational control of E2f1 regulates the Drosophila cell cycle
Jan Inge Øvrebø, Mary-Rose Bradley-Gill, Jussi Taipale, Minhee Kim, Marco Marchetti, Jonathan Bohlen, Mitchell R. Lewis, Monique van Straaten, Nam-Sung Moon, Bruce A. Edgar · 2022 · Proceedings of the National Academy of Sciences
Translation Regulation in Skin Cancer from a tRNA Point of View
Katerina Grafanaki, Dimitrios G. Anastasakis, George C. Kyriakopoulos, Ilias Skeparnias, Sophia Georgiou, Constantinos Stathopoulos · 2018 · Epigenomics
Translation dysregulation in cancer as a source for targetable antigens
Chen Weller, Osnat Bartok, Christopher S. McGinnis, Heyilimu Palashati, Tiangen Chang, Dmitry B. Malko, Merav D. Shmueli, Asuteka Nagao, Déborah Hayoun, Ayaka Murayama et al. · 2025 · Cancer Cell
Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion
Ayman Maher Ibrahim, Matthew A. Moss, Zane Gray, Michelle D. Rojo, Caitlin M. Burke, Kathryn L. Schwertfeger, Camila O. dos Santos, Heather L. Machado · 2020 · Frontiers in Oncology
Translational reprogramming of colorectal cancer cells induced by 5-fluorouracil through a miRNA-dependent mechanism
Zeina Bash-Imam, Gabriel Thérizols, Anne Vincent, Florian Laforêts, Micaela Polay Espinoza, Nathalie Pion, Françoise Macari, Julie Pannequin, Alexandre David, Jean‐Christophe Saurin et al. · 2017 · Oncotarget
Fallopian tube lesions as potential precursors of early ovarian cancer: a comprehensive proteomic analysis
Maxence Wisztorski, Soulaimane Aboulouard, Lucas Roussel, Marie Duhamel, Philippe Saudemont, Tristan Cardon, Fabrice Narducci, Y. Marie Robin, Anne-Sophie Lemaire, Delphine Bertin et al. · 2023 · Cell Death and Disease
ALS skin fibroblasts reveal oxidative stress and ERK1/2-mediated cytoplasmic localization of TDP-43
Nicla Romano, Alessia Catalani, Serena Lattante, Antonio Belardo, Silvia Proietti, Laura Bertini, Federica Silvestri, Elisabetta Catalani, Davide Cervia, Lello Zolla et al. · 2020 · Cellular Signalling
Profiling of subcellular EGFR interactome reveals hnRNP A3 modulates nuclear EGFR localization
Tong‐Hong Wang, Chih‐Ching Wu, Kuo‐Yen Huang, Wen‐Yu Chuang, Chuen Hsueh, Hsin‐Jung Li, Chi‐Yuan Chen · 2020 · Oncogenesis
A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer
Regina Cencic, Young Kyuen Im, Sai Kiran Naineni, Mohamed Moustafa-Kamal, Predrag Jovanovic, Valérie Sabourin, Matthew G. Annis, Francis Robert, T.M. Schmeing, Antonis E. Koromilas et al. · 2024 · Proceedings of the National Academy of Sciences
Decoding the ribosome's hidden language: rRNA modifications as key players in cancer dynamics and targeted therapies
Li Cui, Jiarong Zheng, Yunfan Lin, Pei Lin, Ye Lu, Yucheng Zheng, Bing Guo, Xinyuan Zhao · 2024 · Clinical and Translational Medicine
Structure of the RNA Specialized Translation Initiation Element that Recruits eIF3 to the 5′-UTR of c-Jun
Matthew J. P. Walker, Matthew D. Shortridge, Dreycey Albin, Lauren Y. Cominsky, Gabriele Varani · 2020 · Journal of Molecular Biology
Increased expression of tryptophan and tyrosine tRNAs elevates stop codon readthrough of reporter systems in human cell lines
Petra Beznosková, Laure Bidou, Olivier Namy, Leoš Shivaya Valášek · 2021 · Nucleic Acids Research
Decreasing Eukaryotic Initiation Factor 3C (EIF3C) Suppresses Proliferation and Stimulates Apoptosis in Breast Cancer Cell Lines Through Mammalian Target of Rapamycin (mTOR) Pathway
Weipeng Zhao, Xichuan Li, Jun Wang, Chen Wang, Yongsheng Jia, Shunzong Yuan, Yong Huang, Yehui Shi, Zhongsheng Tong · 2017 · Medical Science Monitor
The impact of tRNA modifications on translation in cancer: identifying novel therapeutic avenues
Ana M. Añazco-Guenkova, Borja Miguel‐López, Óscar Monteagudo-García, Raquel García-Vílchez, Sandra Blanco · 2024 · NAR Cancer
Translatome analysis at the egg-to-embryo transition in sea urchin
Héloïse Chassé, Julie Aubert, Sandrine Boulben, Gildas Le Corguillé, Erwan Corre, Patrick Cormier, Julia Morales · 2018 · Nucleic Acids Research
Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition
Cuiqing Fan, Chuntao Zhao, Feng Zhang, Meenu Kesarwani, Zhaowei Tu, Xiongwei Cai, Ashley Kuenzi Davis, Lingli Xu, Cindy L. Hochstetler, Xiaoyi Chen et al. · 2020 · Proceedings of the National Academy of Sciences
Transcription Factors in Breast Cancer—Lessons From Recent Genomic Analyses and Therapeutic Implications
Eldad Zacksenhaus, Jin-kun Liu, Zhe Jiang, Y. Yao, L. Xia, Mariusz Shrestha, Yaacov Ben‐David · 2016 · Advances in protein chemistry and structural biology
The CXCR4-LASP1-eIF4F Axis Promotes Translation of Oncogenic Proteins in Triple-Negative Breast Cancer Cells
Cory M. Howard, Nicole R. Bearss, Boopathi Subramaniyan, Augustus M. C. Tilley, Sangita Sridharan, Nancy Villa, Christopher S. Fraser, Dayanidhi Raman · 2019 · Frontiers in Oncology
METTL3 as a master regulator of translation in cancer: mechanisms and implications
Margalida Esteva-Socias, Francesca Aguiló · 2024 · NAR Cancer
Molecular profiling of single organelles for quantitative analysis of cellular heterogeneity
Andrey N. Kuzmin, Svitlana M. Levchenko, Artem Pliss, Junle Qu, Paras N. Prasad · 2017 · Scientific Reports
LIN28B alters ribosomal dynamics to promote metastasis in MYCN-driven malignancy
Pavlos Missios, Edroaldo Lummertz da Rocha, Daniel S. Pearson, Julia Philipp, Maria M. Aleman, Mehdi Pirouz, Dorian Farache, Joseph Wang Franses, Caroline Kubaczka, Kaloyan M. Tsanov et al. · 2021 · Journal of Clinical Investigation
By reducing global mRNA translation in several ways, 2-deoxyglucose lowers MCL-1 protein and sensitizes hemopoietic tumor cells to BH3 mimetic ABT737
Maximilien Tailler, Lisa Lindqvist, Leonie Gibson, Jerry M. Adams · 2018 · Cell Death and Differentiation
Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress
Elise Y. Cai, Megan Kufeld, Samantha L. Schuster, Sonali Arora, Madeline Larkin, Alexandre A. Germanos, Andrew Caleb Hsieh, Slobodan Beronja · 2020 · Cell stem cell
The biological process of lysine‐tRNA charging is therapeutically targetable in liver cancer
Ruyi Zhang, Lisanne Noordam, Xumin Ou, Buyun Ma, Yunlong Li, Pronay Das, Shaojun Shi, Jiaye Liu, Ling Wang, Pengfei Li et al. · 2020 · Liver International
Novel eIF4A1 inhibitors with anti‐tumor activity in lymphoma
Forum B Kayastha, Noah B. Herrington, Bandish B. Kapadia, Anirban Roychowdhury, Nahid M. Nanaji, Glen E. Kellogg, Ronald B. Gartenhaus · 2022 · Molecular Medicine
Cell Fate Control by Translation: mRNA Translation Initiation as a Therapeutic Target for Cancer Development and Stem Cell Fate Control
Hyun‐Jung Kim · 2019 · Biomolecules
mountainClimber Identifies Alternative Transcription Start and Polyadenylation Sites in RNA-Seq
Ashley A. Cass, Xinshu Grace Xiao · 2019 · Cell Systems
CDK13 phosphorylates the translation machinery and promotes tumorigenic protein synthesis
Chao Wu, Ting Xie, Ying Guo, Donghai Wang, Min Qiu, Ruyi Han, G. Qing, Kai-Wei Liang, Hu-Dan Liu · 2023 · Oncogene
Therapeutic targeting of CNBP phase separation inhibits ribosome biogenesis and neuroblastoma progression via modulating SWI/SNF complex activity
Anpei Hu, Guo Chen, Banghe Bao, Yanhua Guo, Dan Li, Xiaojing Wang, Jianqun Wang, Qilan Li, Yi Zhou, Haiyang Gao et al. · 2023 · Clinical and Translational Medicine
Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma
Walderik W. Zomerman, Sabine L. A. Plasschaert, Siobhan Conroy, Frank J.G. Scherpen, Tiny Meeuwsen-de Boer, Harm Jan Lourens, Sergi Guerrero Llobet, Marlinde J. Smit, Lorian Slagter‐Menkema, Annika Seitz et al. · 2018 · Cell Reports
tRic: a user-friendly data portal to explore the expression landscape of tRNAs in human cancers
Zhao Zhang, Hang Ruan, Chunjie Liu, Youqiong Ye, Jing Gong, Lixia Diao, An‐Yuan Guo, Leng Han · 2019 · RNA Biology
eEF1Bγ binds the Che-1 and TP53 gene promoters and their transcripts
Cinzia Pisani, Annalisa Onori, Francesca Gabanella, Francesca Delle Monache, Antonella Borreca, Martine Ammassari‐Teule, Maurizio Fanciulli, Maria Grazia Di Certo, Claudio Passananti, Nicoletta Corbi · 2016 · Journal of Experimental & Clinical Cancer Research
Y-box Binding Protein 1: Looking Back to the Future
Valentina E. Evdokimova · 2022 · Biochemistry (Moscow)
Disrupting the MYC-TFEB Circuit Impairs Amino Acid Homeostasis and Provokes Metabolic Anergy
Mario R. Fernandez, Franz X. Schaub, Chunying Yang, Weimin Li, Seongseok Yun, Stephanie K. Schaub, Frank Charles Dorsey, Min Liu, Meredith A. Steeves, Andrea Ballabio et al. · 2022 · Cancer Research
Evidence for the importance of post-transcriptional regulatory changes in ovarian cancer progression and the contribution of miRNAs
Mengnan Zhang, Lilya V. Matyunina, L. DeEtte Walker, Weixuan Chen, Haopeng Xiao, Benedict B. Benigno, Ronghu Wu, John F. McDonald · 2017 · Scientific Reports
The role of RNA-binding and ribosomal proteins as specific RNA translation regulators in cellular differentiation and carcinogenesis
Marcello Ceci, Francesco Fazi, Nicla Romano · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition
Chaitra Rao, Danielle E. Frodyma, Siddesh Southekal, Robert A. Svoboda, Adrian R. Black, Chittibabu Guda, Tomohiro Mizutani, Hans C. Clevers, Keith R. Johnson, Kurt W. Fisher et al. · 2021 · eLife
eEF1A1 promotes colorectal cancer progression and predicts poor prognosis of patients
Ahui Fan, Xiaojuan Zhao, Hao Liu, Danxiu Li, Tongtong Guo, Jiehao Zhang, Lili Duan, Hao Cheng, Yongzhan Nie, Daiming Fan et al. · 2022 · Cancer Medicine
FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
Joel William Francis, Simone Hausmann, Sabeen Ikram, Kunlun Yin, Robert Mealey-Farr, Natasha Mahealani Flores, Annie Truc Trinh, Tourkian Chasan, Julia Thompson, Pawel Karol Mazur et al. · 2024 · Molecular Cell
Estrogen receptor α promotes protein synthesis by fine-tuning the expression of the eukaryotic translation initiation factor 3 subunit f (eIF3f)
Rafael Cuesta, Adi Y. Berman, Anya Alayev, Marina K. Holz · 2018 · Journal of Biological Chemistry
The Secret Life of Translation Initiation in Prostate Cancer
Greco Hernández, Jorge L. Ramírez, Abraham Pedroza‐Torres, Luis A. Herrera, Miguel Ángel Jiménez-Ríos · 2019 · Frontiers in Genetics
Non-stem bladder cancer cell-derived extracellular vesicles promote cancer stem cell survival in response to chemotherapy
Wei-Min Chung, Ryan D. Molony, Yi‐Fen Lee · 2021 · Stem Cell Research & Therapy
KLF16 enhances stress tolerance of colorectal carcinomas by modulating nucleolar homeostasis and translational reprogramming
Xiaodan Ma, Shuidan Xu, Shi-Hui Hao, Kai Han, Jie-Wei Chen, Han Ling, Rixin Chen, Xiaohan Jin, Jinghua Cao, Jin‐Long Lin et al. · 2022 · Molecular Therapy
The complex interplay between redox dysregulation and mTOR signaling pathway in cancer: A rationale for cancer treatment
Christophe Glorieux, Cinthya Enriquez-Lara, Pedro Buc Calderón · 2024 · Biochemical Pharmacology
Bone marrow mesenchymal stromal cells support translation in refractory acute myeloid leukemia
Livia E. Lisi-Vega, Alice Pievani, María García-Fernández, Dorian Forte, Tim Williams, Marta Serafini, Simón Méndez‐Ferrer · 2024 · Cell Reports
Regulation of mRNA Translation by Hormone Receptors in Breast and Prostate Cancer
Jianling Xie, Eric P. Kusnadi, Luc Furic, Luke A. Selth · 2021 · Cancers
The Polyamine–Hypusine Circuit Controls an Oncogenic Translational Program Essential for Malignant Conversion in MYC-Driven Lymphoma
Shima Nakanishi, Jiannong Li, Anders Berglund, Youngchul Kim, Yonghong Zhang, Ling Zhang, Chunying Yang, Jinming Song, Raghavendra G. Mirmira, John L. Cleveland · 2023 · Blood Cancer Discovery
CD40L/IL-4–stimulated CLL demonstrates variation in translational regulation of DNA damage response genes including ATM
Larissa Lezina, Ruth V. Spriggs, Daniel Beck, Carolyn Jones, Kate Dudek, Aleksandra Bzura, George D.D. Jones, Graham Packham, Anne E. Willis, Simon D. Wagner · 2018 · Blood Advances
Discovery and Preliminary Characterization of Translational Modulators that Impair the Binding of eIF6 to 60S Ribosomal Subunits
Elisa Pesce, Annarita Miluzio, Lorenzo Turcano, Claudia Minici, Delia Cirino, Piera Calamita, Nicola Manfrini, Stefania Oliveto, Sara Ricciardi, Renata Grifantini et al. · 2020 · Cells
Analysis of fusion transcripts indicates widespread deregulation of snoRNAs and their host genes in breast cancer
Helena Persson, Rolf Søkilde, Jari Häkkinen, Johan Vallon‐Christersson, Felix Mitelman, Åke Borg, Mattias Höglund, Carlos Rovira · 2020 · International Journal of Cancer
Translation initiation and its relevance in colorectal cancer
Emma Minnee, William J. Faller · 2020 · FEBS Journal
RNA G-quadruplexes control mitochondria-localized mRNA translation and energy metabolism
Leïla Dumas, Sauyeun Shin, Quentin Rigaud, Marie Cargnello, Beatriz Hernández Suárez, Pauline Herviou, Nathalie Saint‐Laurent, Marjorie Leduc, Morgane Le Gall, David Monchaud et al. · 2025 · Nature Communications
Relaxed initiation pausing of ribosomes drives oncogenic translation
Leiming Dong, Yuanhui Mao, Aidong Zhou, Xiaomin Liu, Jun Liang Zhou, Ji Wan, Shu‐Bing Qian · 2021 · Science Advances
Heterogeneity and dynamic of EMT through the plasticity of ribosome and mRNA translation
Chloé Morin, Caroline Moyret‐Lalle, Hichem C. Mertani, Jean‐Jacques Diaz, Virginie Marcel · 2022 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Targeting mTOR as a Therapeutic Approach in Medulloblastoma
Juncal Aldaregia, Ainitze Odriozola, Ander Matheu, Idoia García · 2018 · International Journal of Molecular Sciences
Identification of additional regulatory RNPs that impact rRNA and U6 snRNA methylation
Marilyn F. Burke, Madelyn K. Logan, Michael D. Hebert · 2018 · Biology Open
mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine
Mahabub Alam, Hiroki Shima, Y. Matsuo, L. C. Nguyen, Mitsuyo Matsumoto, Y. Ishii, Nichika Sato, Takato Sugiyama, Risa Nobuta, Satoshi Hashimoto et al. · 2022 · Journal of Biological Chemistry
Translational Control of Metabolism and Cell Cycle Progression in Hepatocellular Carcinoma
Alessandra Scagliola, Annarita Miluzio, Stefano Biffo · 2023 · International Journal of Molecular Sciences
Somatic mutation driven codon transition bias in human cancer
Hyeonju Son, Hyundeok Kang, Hyun Seok Kim, Sangwoo Kim · 2017 · Scientific Reports
Stochastic models of Mendelian and reverse transcriptional inheritance in state-structured cancer populations
Anuraag Bukkuri, Kenneth J. Pienta, Robert H. Austin, Emma U. Hammarlund, Sarah R. Amend, Joel S. Brown · 2022 · Scientific Reports
Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis
Adaku, Nneoma, Ostendorf, Benjamin N., Mei, Wenbin, Tavazoie, Sohail F. · 2023 · Cancer Research
Transcriptomic analysis and fusion gene identifications of midbody remnants released from colorectal cancer cells reveals they are molecularly distinct from exosomes and microparticles
Wittaya Suwakulsiri, Rong Xu, Alin Rai, Maoshan Chen, Adnan Shafiq, David W. Greening, Richard J. Simpson · 2024 · PROTEOMICS
Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors
Sebastian Lampe, Michael M. Kunze, Anica Scholz, Thilo F. Brauß, Sofia Winslow, Stefan Simm, Mario Keller, Juliana Heidler, Ilka Wittig, Bernhard Brüne et al. · 2018 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
Ribosome profiling unveils translational regulation of metabolic enzymes in primary CD4+ Th1 cells
Nicola Manfrini, Sara Ricciardi, Roberta R Alfieri, Gabriele Ventura, Piera Calamita, Andrea Favalli, Stefano Biffo · 2020 · Developmental & Comparative Immunology
Sequestration of eIF4A by angiomotin: A novel mechanism to restrict global protein synthesis in trophoblast cells
Trishita Basak, A. Dey, R. Banerjee, Sandip Paul, T. Maiti, R. Ain · 2020 · Stem Cells