The DOI matches its Crossref record; 126 of the 126 references it cites were found in a registry or an index.
Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
Open accessAbstract
In recent years there has been a growing interest among cancer biologists in cancer metabolism. This Review summarizes past and recent advances in our understanding of the reprogramming of glucose metabolism in cancer cells, which is mediated by oncogenic drivers and by the undifferentiated character of cancer cells. The reprogrammed glucose metabolism in cancer cells is required to fulfil anabolic demands. This Review discusses the possibility of exploiting the reprogrammed glucose metabolism for therapeutic approaches that selectively target cancer cells.
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Cites
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Cited by
Drug resistance and combating drug resistance in cancer
Wang, X., Zhang, H., & Chen, X. (2019) · Cancer Drug Resistance · doi:10.20517/cdr.2019.10 · Cited by 1,085
Targeting Metabolism for Cancer Therapy
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ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway
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DeWaal, D., Nogueira, V., Terry, A. R., Patra, K. C., Jeon, S.-M., Guzman, G., Au, J., Long, C. P., Antoniewicz, M. R., & Hay, N. (2018) · Nature Communications · doi:10.1038/s41467-017-02733-4 · Cited by 525
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Self-citation
Metadata
- Authors
- Hay, N.
- Venue
- Nature Reviews Cancer
- Published
- 2016-09-16
- Volume
- 16
- Issue
- 10
- Pages
- 635-649
- ISSN
- 1474-175X (ISSN-L)
- 1474-1768
- OpenAlex
- W2519942994
- Cited by
- 1,115
- References
- 126
- FWCI
- 7.16
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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