The DOI matches its Crossref record; 93 of the 93 references it cites were found in a registry or an index.
Impact of oncogenic pathways on evasion of antitumour immune responses
Open accessAbstract
Immunotherapeutic interventions are showing effectiveness across a wide range of cancer types, but only a subset of patients shows clinical response to therapy. Responsiveness to checkpoint blockade immunotherapy is favoured by the presence of a local, CD8+ T cell-based immune response within the tumour microenvironment. As molecular analyses of tumours containing or lacking a productive CD8+ T cell infiltrate are being pursued, increasing evidence is indicating that activation of oncogenic pathways in tumour cells can impair induction or execution of a local antitumour immune response. This Review summarizes our current knowledge of the influence of oncogenic effects on evasion of antitumour immunity.
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The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
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Advances in immunotherapy for hepatocellular carcinoma
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Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy
Skoulidis, F., & Heymach, J. V. (2019) · Nature Reviews Cancer · doi:10.1038/s41568-019-0179-8 · Cited by 1,019
Metadata
- Authors
- Spranger, S., & Gajewski, T. F.
- Venue
- Nature Reviews Cancer
- Published
- 2018-01-12
- Volume
- 18
- Issue
- 3
- Pages
- 139-147
- ISSN
- 1474-175X (ISSN-L)
- 1474-1768
- OpenAlex
- W2782949806
- Cited by
- 665
- References
- 93
- FWCI
- 10.09
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
