Targeting Autophagy in Cancer
Levy, Jean M. Mulcahy, Towers, Christina G., Thorburn, Andrew·2017·Nature Reviews Cancer
Cited by (1,004)
Items 201–300 of 1,004
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- A novel long noncoding RNA SP100-AS1 induces radioresistance of colorectal cancer via sponging miR-622 and stabilizing ATG3You Zhou, Yingjie Shao, Wenwei Hu, Jinping Zhang, Yufang Shi, Xiangyin Kong, Jingting Jiang · 2022 · Cell Death and Differentiation
- Role of Autophagy in Endothelial Damage and Blood–Brain Barrier Disruption in Ischemic StrokeKyeong-A Kim, Donggeun Shin, Jeong‐Hyeon Kim, Young‐Jun Shin, Golgodu Krishnamurthy Rajanikant, Arshad Majid, Seung‐Hoon Baek, Ok‐Nam Bae · 2018 · Stroke
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- Autophagy suppression of trophoblast cells induces pregnancy loss by activating decidual NK cytotoxicity and inhibiting trophoblast invasionHai-Xia Tan, Shao‐Liang Yang, Ming‐Qing Li, Haiyan Wang · 2020 · Cell Communication and Signaling
- Down-regulated ciRS-7/up-regulated miR-7 axis aggravated cartilage degradation and autophagy defection by PI3K/AKT/mTOR activation mediated by IL-17A in osteoarthritisXindie Zhou, Li Jin, Yuanshuai Zhou, Zhicheng Yang, Haoyu Yang, Dong Li, Junjie Zhang, Yi Zhang, Nanwei Xu, Yong Huang et al. · 2020 · Aging
- Lenvatinib in hepatocellular carcinoma: Resistance mechanisms and strategies for improved efficacyYongqing Qin, Shisong Han, Yahan Yu, Qi Ding, Mengnan Ran, Mingqi Yang, Yanyan Liu, Yunyi Li, Ligong Lu, Yu Liu et al. · 2024 · Liver International
- PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer CellsChunle Zhao, Ruizhi He, Ming Shen, Feng Zhu, Min Wang, Yuhui Liu, Hua Chen, Li Xu, Renyi Qin · 2019 · Frontiers in Pharmacology
- Molecular Mechanisms Underlying Autophagy-Mediated Treatment Resistance in CancerCally J. Ho, Sharon M. Gorski · 2019 · Cancers
- Delivery of MutT homolog 1 inhibitor by functionalized graphene oxide nanoparticles for enhanced chemo-photodynamic therapy triggers cell death in osteosarcomaXin Huang, Jing Chen, Wei Wu, Wenbo Yang, Binlong Zhong, Xiangcheng Qing, Zengwu Shao · 2020 · Acta Biomaterialia
- Relevance of Autophagy in Parenchymal and Non-Parenchymal Liver Cells for Health and DiseaseRalf Weiskirchen, Frank Tacke · 2019 · Cells
- Regulation of Autophagy by Nuclear GAPDH and Its Aggregates in Cancer and Neurodegenerative DisordersGiovanna Butera, Nidula Mullappilly, Francesca Masetto, Marta Palmieri, Maria Teresa Scupoli, Raffaella Pacchiana, Massimo Donadelli · 2019 · International Journal of Molecular Sciences
- MicroRNA-Based Combinatorial Cancer Therapy: Effects of MicroRNAs on the Efficacy of Anti-Cancer TherapiesHyun Ah Seo, Sokviseth Moeng, Seokmin Sim, Hyo Jeong Kuh, Soo Young Choi, Jong Kook Park · 2019 · Cells
- SGK1 in Human Cancer: Emerging Roles and MechanismsYiwen Sang, Piaoping Kong, Shizhen Zhang, Lingyu Zhang, Ying Cao, Xiuzhi Duan, Tao Sun, Zhihua Tao, Weiwei Liu · 2021 · Frontiers in Oncology
- Chemoresistance and Metastasis in Breast Cancer Molecular Mechanisms and Novel Clinical StrategiesJun Cao, Mengdi Zhang, Bin Wang, Long Zhang, Fangfang Zhou, Meiyu Fang · 2021 · Frontiers in Oncology
- The progression of HMGB1-induced autophagy in cancer biologyTianwei Xu, Lihua Jiang, Zhaoxia Wang · 2018 · OncoTargets and Therapy
- Autophagy inhibitors for cancer therapy: Small molecules and nanomedicinesJianli Chen, Xuan Wu, Dan Yin, Xiao-Hui Jia, Xu Chen, Zeyun Gu, Xiaoming Zhu · 2023 · Pharmacology & Therapeutics
- Repurposing of plant alkaloids for cancer therapy: Pharmacology and toxicologyThomas Efferth, Franz Oesch · 2019 · Seminars in Cancer Biology
- Advancing Cancer Treatment by Targeting Glutamine Metabolism—A RoadmapAnna Halama, Karsten Suhre · 2022 · Cancers
- Furin-instructed aggregated gold nanoparticles for re-educating tumor associated macrophages and overcoming breast cancer chemoresistanceRou Xie, Shaobo Ruan, Jiaqi Liu, Lin Qin, Chuanyao Yang, Fan Tong, Ting Lei, Maxim Alekseevich Shevtsov, Huile Gao, Yi Qin · 2021 · Biomaterials
- NCAPD2 inhibits autophagy by regulating Ca2+/CAMKK2/AMPK/mTORC1 pathway and PARP-1/SIRT1 axis to promote colorectal cancerZuolei Jing, Xinyuan He, Zhirong Jia, Yunli Sa, Bolin Yang, Ping Liu · 2021 · Cancer Letters
- Photodynamic Therapy Based on Nanoscale Metal–Organic Frameworks: From Material Design to Cancer NanotherapeuticsQun Guan, Yan‐An Li, Wen‐Yan Li, Yu‐Bin Dong · 2018 · Chemistry - An Asian Journal
- Curcumin and its analogues protect from endoplasmic reticulum stress: mechanisms and pathways.A. Shakeri, M. Zirak, A. Hayes, R. Reiter, G. Karimi · 2019 · Pharmacological Research
- Autophagy Modulators: Mechanistic Aspects and Drug Delivery SystemsShima Tavakol, Milad Ashrafizadeh, Shuo Deng, Maryam Azarian, Asghar Abdoli, Mahsa Motavaf, Delaram Poormoghadam, Hashem Khanbabaei, Elham Ghasemipour Afshar, Ali Mandegary et al. · 2019 · Biomolecules
- Asbestos induces mesothelial cell transformation via HMGB1-driven autophagyJiaming Xue, Simone Patergnani, Carlotta Giorgi, Joelle Sacks Suarez, Keisuke Goto, Angela Bononi, Mika Tanji, Flavia Novelli, Sandra Pastorino, Ronghui Xu et al. · 2020 · Proceedings of the National Academy of Sciences
- Autophagy: A challengeable paradox in cancer treatmentFarnaz Ahmadi‐Dehlaghi, Parisa Mohammadi, Elahe Valipour, Pouya Pournaghi, Sara Kiani, Kamran Mansouri · 2023 · Cancer Medicine
- Drug repurposing for the treatment of glioblastoma multiformeClaudia Abbruzzese, Silvia Matteoni, Michele Signore, Luca Cardone, Kavindra Nath, Jerry D. Glickson, Marco Giorgio Paggi · 2017 · Journal of Experimental & Clinical Cancer Research
- YAP promotes autophagy and progression of gliomas via upregulating HMGB1Min Zhao, Yu Zhang, Yang Jiang, Kai Wang, Xiang Wang, Ding Zhou, Yan Wang, Rutong Yu, Xiuping Zhou · 2021 · Journal of Experimental & Clinical Cancer Research
- Targeting Autophagy in the Tumor Microenvironment: New Challenges and Opportunities for Regulating Tumor ImmunityBassam Janji, Guy Berchem, Salem Chouaı̈b · 2018 · Frontiers in Immunology
- The role of cell signaling in the crosstalk between autophagy and apoptosis in the regulation of tumor cell survival in response to sorafenib and neratinibLaurence A. Booth, Jane L. Roberts, Paul Dent · 2019 · Seminars in Cancer Biology
- A Review of ULK1-Mediated Autophagy in Drug Resistance of CancerLi Liu, Lu Yan, Ning Liao, Wan-Qin Wu, Junling Shi · 2020 · Cancers
- Dehydrodiisoeugenol inhibits colorectal cancer growth by endoplasmic reticulum stress-induced autophagic pathwaysChanghong Li, Kui Zhang, Guangzhao Pan, Haoyan Ji, Chongyang Li, Xiaowen Wang, Xin Hu, Ruochen Liu, Longfei Deng, Yì Wáng et al. · 2021 · Journal of Experimental & Clinical Cancer Research
- Hydroxychloroquine: A Physiologically-Based Pharmacokinetic Model in the Context of Cancer-Related Autophagy ModulationKeagan P. Collins, Kristen M. Jackson, Daniel L. Gustafson · 2018 · Journal of Pharmacology and Experimental Therapeutics
- HAMdb: a database of human autophagy modulators with specific pathway and disease informationWang, Ning-Ning, Dong, Jie, Zhang, Lin, Ouyang, Defang, Cheng, Yan, Chen, Alex F., Lu, Ai-Ping, Cao, Dong-Sheng · 2018 · Journal of Cheminformatics
- Role of heparanase in tumor progression: Molecular aspects and therapeutic optionsValentina Masola, Gianluigi Zaza, Giovanni Gambaro, Marco Franchi, Maurizio Onisto · 2019 · Seminars in Cancer Biology
- Pyroptosis, ferroptosis, and autophagy cross-talk in glioblastoma opens up new avenues for glioblastoma treatmentSicheng Wan, Guanghui Zhang, Ruochen Liu, Muhammad Nadeem Abbas, Hongjuan Cui · 2023 · Cell Communication and Signaling
- The Roles of p53 in Mitochondrial Dynamics and Cancer Metabolism: The Pendulum between Survival and Death in Breast Cancer?David E. Moulder, Diana Hatoum, Enoch S. E. Tay, Yiguang Lin, Eileen M. McGowan · 2018 · Cancers
- High-selective HDAC6 inhibitor promotes HDAC6 degradation following autophagy modulation and enhanced antitumor immunity in glioblastomaJia-Rong Liu, Chao‐Wu Yu, Pei-Yun Hung, Ling‐Wei Hsin, Ji‐Wang Chern · 2019 · Biochemical Pharmacology
- Current State of Knowledge on Salivary Gland CancersHer Helen Lin, Kirsten H. Limesand, David Kong Ann · 2018 · Critical Reviews™ in Oncogenesis
- MYC and the unfolded protein response in cancer: synthetic lethal partners in crime?Tingting Zhang, Ningning Li, Chaoyang Sun, Yang Jin, Xia Sheng · 2020 · EMBO Molecular Medicine
- Drug repurposing against COVID-19: focus on anticancer agentsG. Ciliberto, R. Mancini, M. G. Paggi · 2020 · Journal of experimental & clinical cancer research : CR
- The Cancer Chemopreventive and Therapeutic Potential of TetrahydrocurcuminChing‐Shu Lai, Chi‐Tang Ho, Min‐Hsiung Pan · 2020 · Biomolecules
- CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/AKT-mediated autophagyChen Zhao, Xiaodong Li, Guantong Sun, Pengcheng Liu, Keyu Kong, Xuzhuo Chen, Fei Yang, Xiaoqing Wang · 2022 · Cell Death and Disease
- Autophagy role(s) in response to oncogenes and DNA replication stressVanzo, Riccardo, Bartkova, Jirina, Merchut-Maya, Joanna Maria, Hall, Arnaldur, Bouchal, Jan, Dyrskjøt, Lars, Frankel, Lisa B., Gorgoulis, Vassilis, Maya-Mendoza, Apolinar, Jäättelä, Marja et al. · 2020 · Cell Death & Differentiation
- Autophagy and diseaseAndrew M. Thorburn · 2017 · Journal of Biological Chemistry
- A randomized, double-blind, window of opportunity trial evaluating the effects of chloroquine in breast cancer patientsAngel Arnaout, Susan J. Robertson, Gregory R. Pond, Hoyun Lee, Ahwon Jeong, Luisa Ianni, Lynne Kroeger, John Frederick Hilton, Stuart Glenn Coupland, Chloe Gottlieb et al. · 2019 · Breast Cancer Research and Treatment
- Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosisNingning Wang, Hongzhi Liu, Guijun Liu, Min Li, Xuxiao He, Chunzhao Yin, Qiaochu Tu, Xia Shen, Wenqiang Bai, Qiang Wang et al. · 2020 · Redox Biology
- Mitochondrial Metabolism in PDAC: From Better Knowledge to New Targeting StrategiesGabriela Reyes‐Castellanos, Rawand Masoud, Alice Carrier · 2020 · Biomedicines
- Ursolic and Oleanolic Acids Induce Mitophagy in A549 Human Lung Cancer CellsNayeli Shantal Castrejón-Jiménez, Kahiry Leyva-Paredes, Shantal Lizbeth Baltierra‐Uribe, Juan Castillo-Cruz, Marcia Campillo-Navarro, Alma Delia Hernández‐Pérez, Alexandra Berenice Luna‐Angulo, Rommel Chacón‐Salinas, Ramón Mauricio Coral‐Vázquez, Iris Estrada‐García et al. · 2019 · Molecules
- Glucocorticoids Enhanced Osteoclast Autophagy Through the PI3K/Akt/mTOR Signaling PathwayLingjie Fu, Wen Wu, Xiaojiang Sun, Pu Zhang · 2020 · Calcified Tissue International
- Autophagy is a major metabolic regulator involved in cancer therapy resistanceLaura Poillet-Perez, Jean‐Emmanuel Sarry, Carine Joffre · 2021 · Cell Reports
- Targeted Inhibition of ULK1 Promotes Apoptosis and Suppresses Tumor Growth and Metastasis in NeuroblastomaChristopher M. Dower, Neema Bhat, Melat T. Gebru, Longgui Chen, Carson A. Wills, Barbara A. Miller, Hong‐Gang Wang · 2018 · Molecular Cancer Therapeutics
- Rapamycin Induced Autophagy Inhibits Inflammation-Mediated Endplate Degeneration by Enhancing Nrf2/Keap1 Signaling of Cartilage Endplate Stem CellsRui Min Zuo, Yanqiu Wang, Jie Li, Junlong Wu, Wenkai Wang, Bin Li, Chao Sun, Ziwen Wang, Chunmeng Shi, Yue Zhou et al. · 2019 · Stem Cells
- Autophagy-related protein PIK3C3/VPS34 controls T cell metabolism and functionGuan Yang, Wenqiang Song, Joshua Luke Postoak, Jin Chen, Jennifer Martinez, Jianhua Zhang, Lan Wu, Luc Van Kaer · 2020 · Autophagy
- TGF‑β1‑induced autophagy activates hepatic stellate cells via the ERK and JNK signaling pathwaysJing Zhang, Na Jiang, Ping Jian, Lieming Xu · 2020 · International Journal of Molecular Medicine
- Autophagy Activation Represses Pyroptosis through the IL-13 and JAK1/STAT1 Pathways in a Mouse Model of Moderate Traumatic Brain InjuryCheng Gao, Yanan Yan, Guang Chen, Tao Wang, Chengliang Luo, Mingyang Zhang, Xiping Chen, Luyang Tao · 2020 · ACS Chemical Neuroscience
- The evolution and ecology of benign tumorsJustine Boutry, Sophie Tissot, Beáta Újvári, Jean‐Pascal Capp, Mathieu Giraudeau, Aurora M. Nedelcu, Frédéric Thomas A · 2021 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- A bioinformatics analysis, pre-clinical and clinical conception of autophagy in pancreatic cancer: Complexity and simplicity in crosstalkMilad Ashrafizadeh, Wei Zhang, Rongjun Zou, Gautam Sethi, Daniel J. Klionsky, Xianbin Zhang · 2023 · Pharmacological Research
- HPV E6/E7: insights into their regulatory role and mechanism in signaling pathways in HPV-associated tumorPeng Qiu, Lujuan Wang, Liang Zuo, Shuichao Gao, Xianjie Jiang, Yaqian Han, Jinguan Lin, Mingjing Peng, Nayiyuan Wu, Yanyan Tang et al. · 2023 · Cancer Gene Therapy
- Targeting the Lysosome for Cancer TherapyChristina G. Towers, Andrew M. Thorburn · 2017 · Cancer Discovery
- Autophagy Paradox of Cancer: Role, Regulation, and DualityAmit Kumar Verma, Prahalad Singh Bharti, Sahar Rafat, Deepti Bhatt, Yamini Goyal, Kamlesh Kumar Pandey, Sanjeev Kumar Ranjan, Saleh A. Almatroodi, Mohammed A. Alsahli, Arshad Husain Rahmani et al. · 2021 · Oxidative Medicine and Cellular Longevity
- Autophagy as a target for glucocorticoid-induced osteoporosis therapyGengyang Shen, Hui Jun Ren, Qi Shang, Ting Qiu, Xiang Yu, Zhida Zhang, Jinjing Huang, Wenhua Zhao, Yuzhuo Zhang, De Liang et al. · 2018 · Cellular and Molecular Life Sciences
- Autophagy modulators for the treatment of oral and esophageal squamous cell carcinomasTuhina Khan, Nicola Relitti, Margherita Brindisi, Stefania Magnano, Daniela M. Zisterer, Sandra Gemma, Stefania Butini, Giuseppe Campiani · 2019 · Medicinal Research Reviews
- Sodium propionate exerts anticancer effect in mice bearing breast cancer cell xenograft by regulating JAK2/STAT3/ROS/p38 MAPK signalingHyun-Soo Park, Joo‐Hui Han, Jeong Won Park, Do-Hyung Lee, Keun‐Woo Jang, Miji Lee, Kyung‐Sun Heo, Chang‐Seon Myung · 2020 · Acta Pharmacologica Sinica
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