Targeting Autophagy in Cancer

Levy, Jean M. Mulcahy, Towers, Christina G., Thorburn, Andrew·2017·Nature Reviews Cancer

Cited by (1,004)

Items 201–300 of 1,004

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    Siyue Zhang, Fangyuan Xie, Kaichun Li, He Zhang, You Yin, Yuan Yu, Guangzhao Lu, Shihao Zhang, Yan Wei, Ke Xu et al. · 2022 · Acta Pharmaceutica Sinica B
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    Guoqiang Dong, Ying Wu, Junfei Cheng, Long Chen, Rui Liu, Yu Ding, Shanchao Wu, Junhui Ma, Chunquan Sheng · 2022 · Journal of Medicinal Chemistry
  3. The Role of Chloroquine and Hydroxychloroquine in Immune Regulation and Diseases
    Gricelis Patricia Martinez, Mercedes E. Zabaleta, Camilo Di Giulio, Jaime Charris, Michael Rodney Mijares · 2020 · Current Pharmaceutical Design
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    Oliviero Marinelli, Maria Beatrice Morelli, Daniela Annibali, Cristina Aguzzi, Laura Zeppa, Sandra Tuyaerts, Consuelo Amantini, Frédéric C. Amant, Benedetta Ferretti, Federica Maggi et al. · 2020 · International Journal of Molecular Sciences
  5. A novel long noncoding RNA SP100-AS1 induces radioresistance of colorectal cancer via sponging miR-622 and stabilizing ATG3
    You Zhou, Yingjie Shao, Wenwei Hu, Jinping Zhang, Yufang Shi, Xiangyin Kong, Jingting Jiang · 2022 · Cell Death and Differentiation
  6. Role of Autophagy in Endothelial Damage and Blood–Brain Barrier Disruption in Ischemic Stroke
    Kyeong-A Kim, Donggeun Shin, Jeong‐Hyeon Kim, Young‐Jun Shin, Golgodu Krishnamurthy Rajanikant, Arshad Majid, Seung‐Hoon Baek, Ok‐Nam Bae · 2018 · Stroke
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    Min Yang, En Liu, Li Tang, Yuanyuan Lei, Xuemei Sun, Jiaxi Hu, Hui Dong, Shiming Yang, Mingfa Gao, Bo Tang · 2018 · Cell Communication and Signaling
  8. Autophagy suppression of trophoblast cells induces pregnancy loss by activating decidual NK cytotoxicity and inhibiting trophoblast invasion
    Hai-Xia Tan, Shao‐Liang Yang, Ming‐Qing Li, Haiyan Wang · 2020 · Cell Communication and Signaling
  9. Down-regulated ciRS-7/up-regulated miR-7 axis aggravated cartilage degradation and autophagy defection by PI3K/AKT/mTOR activation mediated by IL-17A in osteoarthritis
    Xindie Zhou, Li Jin, Yuanshuai Zhou, Zhicheng Yang, Haoyu Yang, Dong Li, Junjie Zhang, Yi Zhang, Nanwei Xu, Yong Huang et al. · 2020 · Aging
  10. Lenvatinib in hepatocellular carcinoma: Resistance mechanisms and strategies for improved efficacy
    Yongqing Qin, Shisong Han, Yahan Yu, Qi Ding, Mengnan Ran, Mingqi Yang, Yanyan Liu, Yunyi Li, Ligong Lu, Yu Liu et al. · 2024 · Liver International
  11. PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells
    Chunle Zhao, Ruizhi He, Ming Shen, Feng Zhu, Min Wang, Yuhui Liu, Hua Chen, Li Xu, Renyi Qin · 2019 · Frontiers in Pharmacology
  12. Molecular Mechanisms Underlying Autophagy-Mediated Treatment Resistance in Cancer
    Cally J. Ho, Sharon M. Gorski · 2019 · Cancers
  13. Delivery of MutT homolog 1 inhibitor by functionalized graphene oxide nanoparticles for enhanced chemo-photodynamic therapy triggers cell death in osteosarcoma
    Xin Huang, Jing Chen, Wei Wu, Wenbo Yang, Binlong Zhong, Xiangcheng Qing, Zengwu Shao · 2020 · Acta Biomaterialia
  14. Relevance of Autophagy in Parenchymal and Non-Parenchymal Liver Cells for Health and Disease
    Ralf Weiskirchen, Frank Tacke · 2019 · Cells
  15. Regulation of Autophagy by Nuclear GAPDH and Its Aggregates in Cancer and Neurodegenerative Disorders
    Giovanna Butera, Nidula Mullappilly, Francesca Masetto, Marta Palmieri, Maria Teresa Scupoli, Raffaella Pacchiana, Massimo Donadelli · 2019 · International Journal of Molecular Sciences
  16. MicroRNA-Based Combinatorial Cancer Therapy: Effects of MicroRNAs on the Efficacy of Anti-Cancer Therapies
    Hyun Ah Seo, Sokviseth Moeng, Seokmin Sim, Hyo Jeong Kuh, Soo Young Choi, Jong Kook Park · 2019 · Cells
  17. SGK1 in Human Cancer: Emerging Roles and Mechanisms
    Yiwen Sang, Piaoping Kong, Shizhen Zhang, Lingyu Zhang, Ying Cao, Xiuzhi Duan, Tao Sun, Zhihua Tao, Weiwei Liu · 2021 · Frontiers in Oncology
  18. Chemoresistance and Metastasis in Breast Cancer Molecular Mechanisms and Novel Clinical Strategies
    Jun Cao, Mengdi Zhang, Bin Wang, Long Zhang, Fangfang Zhou, Meiyu Fang · 2021 · Frontiers in Oncology
  19. The progression of HMGB1-induced autophagy in cancer biology
    Tianwei Xu, Lihua Jiang, Zhaoxia Wang · 2018 · OncoTargets and Therapy
  20. Autophagy inhibitors for cancer therapy: Small molecules and nanomedicines
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  21. Repurposing of plant alkaloids for cancer therapy: Pharmacology and toxicology
    Thomas Efferth, Franz Oesch · 2019 · Seminars in Cancer Biology
  22. Advancing Cancer Treatment by Targeting Glutamine Metabolism—A Roadmap
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  23. Furin-instructed aggregated gold nanoparticles for re-educating tumor associated macrophages and overcoming breast cancer chemoresistance
    Rou Xie, Shaobo Ruan, Jiaqi Liu, Lin Qin, Chuanyao Yang, Fan Tong, Ting Lei, Maxim Alekseevich Shevtsov, Huile Gao, Yi Qin · 2021 · Biomaterials
  24. NCAPD2 inhibits autophagy by regulating Ca2+/CAMKK2/AMPK/mTORC1 pathway and PARP-1/SIRT1 axis to promote colorectal cancer
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  25. Photodynamic Therapy Based on Nanoscale Metal–Organic Frameworks: From Material Design to Cancer Nanotherapeutics
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  26. Curcumin and its analogues protect from endoplasmic reticulum stress: mechanisms and pathways.
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  27. Autophagy Modulators: Mechanistic Aspects and Drug Delivery Systems
    Shima Tavakol, Milad Ashrafizadeh, Shuo Deng, Maryam Azarian, Asghar Abdoli, Mahsa Motavaf, Delaram Poormoghadam, Hashem Khanbabaei, Elham Ghasemipour Afshar, Ali Mandegary et al. · 2019 · Biomolecules
  28. Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy
    Jiaming Xue, Simone Patergnani, Carlotta Giorgi, Joelle Sacks Suarez, Keisuke Goto, Angela Bononi, Mika Tanji, Flavia Novelli, Sandra Pastorino, Ronghui Xu et al. · 2020 · Proceedings of the National Academy of Sciences
  29. Autophagy: A challengeable paradox in cancer treatment
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  30. Drug repurposing for the treatment of glioblastoma multiforme
    Claudia Abbruzzese, Silvia Matteoni, Michele Signore, Luca Cardone, Kavindra Nath, Jerry D. Glickson, Marco Giorgio Paggi · 2017 · Journal of Experimental & Clinical Cancer Research
  31. YAP promotes autophagy and progression of gliomas via upregulating HMGB1
    Min Zhao, Yu Zhang, Yang Jiang, Kai Wang, Xiang Wang, Ding Zhou, Yan Wang, Rutong Yu, Xiuping Zhou · 2021 · Journal of Experimental & Clinical Cancer Research
  32. Targeting Autophagy in the Tumor Microenvironment: New Challenges and Opportunities for Regulating Tumor Immunity
    Bassam Janji, Guy Berchem, Salem Chouaı̈b · 2018 · Frontiers in Immunology
  33. The role of cell signaling in the crosstalk between autophagy and apoptosis in the regulation of tumor cell survival in response to sorafenib and neratinib
    Laurence A. Booth, Jane L. Roberts, Paul Dent · 2019 · Seminars in Cancer Biology
  34. A Review of ULK1-Mediated Autophagy in Drug Resistance of Cancer
    Li Liu, Lu Yan, Ning Liao, Wan-Qin Wu, Junling Shi · 2020 · Cancers
  35. Dehydrodiisoeugenol inhibits colorectal cancer growth by endoplasmic reticulum stress-induced autophagic pathways
    Changhong Li, Kui Zhang, Guangzhao Pan, Haoyan Ji, Chongyang Li, Xiaowen Wang, Xin Hu, Ruochen Liu, Longfei Deng, Yì Wáng et al. · 2021 · Journal of Experimental & Clinical Cancer Research
  36. Hydroxychloroquine: A Physiologically-Based Pharmacokinetic Model in the Context of Cancer-Related Autophagy Modulation
    Keagan P. Collins, Kristen M. Jackson, Daniel L. Gustafson · 2018 · Journal of Pharmacology and Experimental Therapeutics
  37. HAMdb: a database of human autophagy modulators with specific pathway and disease information
    Wang, Ning-Ning, Dong, Jie, Zhang, Lin, Ouyang, Defang, Cheng, Yan, Chen, Alex F., Lu, Ai-Ping, Cao, Dong-Sheng · 2018 · Journal of Cheminformatics
  38. Role of heparanase in tumor progression: Molecular aspects and therapeutic options
    Valentina Masola, Gianluigi Zaza, Giovanni Gambaro, Marco Franchi, Maurizio Onisto · 2019 · Seminars in Cancer Biology
  39. Pyroptosis, ferroptosis, and autophagy cross-talk in glioblastoma opens up new avenues for glioblastoma treatment
    Sicheng Wan, Guanghui Zhang, Ruochen Liu, Muhammad Nadeem Abbas, Hongjuan Cui · 2023 · Cell Communication and Signaling
  40. The Roles of p53 in Mitochondrial Dynamics and Cancer Metabolism: The Pendulum between Survival and Death in Breast Cancer?
    David E. Moulder, Diana Hatoum, Enoch S. E. Tay, Yiguang Lin, Eileen M. McGowan · 2018 · Cancers
  41. High-selective HDAC6 inhibitor promotes HDAC6 degradation following autophagy modulation and enhanced antitumor immunity in glioblastoma
    Jia-Rong Liu, Chao‐Wu Yu, Pei-Yun Hung, Ling‐Wei Hsin, Ji‐Wang Chern · 2019 · Biochemical Pharmacology
  42. Current State of Knowledge on Salivary Gland Cancers
    Her Helen Lin, Kirsten H. Limesand, David Kong Ann · 2018 · Critical Reviews™ in Oncogenesis
  43. MYC and the unfolded protein response in cancer: synthetic lethal partners in crime?
    Tingting Zhang, Ningning Li, Chaoyang Sun, Yang Jin, Xia Sheng · 2020 · EMBO Molecular Medicine
  44. Drug repurposing against COVID-19: focus on anticancer agents
    G. Ciliberto, R. Mancini, M. G. Paggi · 2020 · Journal of experimental & clinical cancer research : CR
  45. The Cancer Chemopreventive and Therapeutic Potential of Tetrahydrocurcumin
    Ching‐Shu Lai, Chi‐Tang Ho, Min‐Hsiung Pan · 2020 · Biomolecules
  46. CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/AKT-mediated autophagy
    Chen Zhao, Xiaodong Li, Guantong Sun, Pengcheng Liu, Keyu Kong, Xuzhuo Chen, Fei Yang, Xiaoqing Wang · 2022 · Cell Death and Disease
  47. Autophagy role(s) in response to oncogenes and DNA replication stress
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  48. Autophagy and disease
    Andrew M. Thorburn · 2017 · Journal of Biological Chemistry
  49. A randomized, double-blind, window of opportunity trial evaluating the effects of chloroquine in breast cancer patients
    Angel Arnaout, Susan J. Robertson, Gregory R. Pond, Hoyun Lee, Ahwon Jeong, Luisa Ianni, Lynne Kroeger, John Frederick Hilton, Stuart Glenn Coupland, Chloe Gottlieb et al. · 2019 · Breast Cancer Research and Treatment
  50. Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis
    Ningning Wang, Hongzhi Liu, Guijun Liu, Min Li, Xuxiao He, Chunzhao Yin, Qiaochu Tu, Xia Shen, Wenqiang Bai, Qiang Wang et al. · 2020 · Redox Biology
  51. Mitochondrial Metabolism in PDAC: From Better Knowledge to New Targeting Strategies
    Gabriela Reyes‐Castellanos, Rawand Masoud, Alice Carrier · 2020 · Biomedicines
  52. Ursolic and Oleanolic Acids Induce Mitophagy in A549 Human Lung Cancer Cells
    Nayeli Shantal Castrejón-Jiménez, Kahiry Leyva-Paredes, Shantal Lizbeth Baltierra‐Uribe, Juan Castillo-Cruz, Marcia Campillo-Navarro, Alma Delia Hernández‐Pérez, Alexandra Berenice Luna‐Angulo, Rommel Chacón‐Salinas, Ramón Mauricio Coral‐Vázquez, Iris Estrada‐García et al. · 2019 · Molecules
  53. Glucocorticoids Enhanced Osteoclast Autophagy Through the PI3K/Akt/mTOR Signaling Pathway
    Lingjie Fu, Wen Wu, Xiaojiang Sun, Pu Zhang · 2020 · Calcified Tissue International
  54. Autophagy is a major metabolic regulator involved in cancer therapy resistance
    Laura Poillet-Perez, Jean‐Emmanuel Sarry, Carine Joffre · 2021 · Cell Reports
  55. Targeted Inhibition of ULK1 Promotes Apoptosis and Suppresses Tumor Growth and Metastasis in Neuroblastoma
    Christopher M. Dower, Neema Bhat, Melat T. Gebru, Longgui Chen, Carson A. Wills, Barbara A. Miller, Hong‐Gang Wang · 2018 · Molecular Cancer Therapeutics
  56. Rapamycin Induced Autophagy Inhibits Inflammation-Mediated Endplate Degeneration by Enhancing Nrf2/Keap1 Signaling of Cartilage Endplate Stem Cells
    Rui Min Zuo, Yanqiu Wang, Jie Li, Junlong Wu, Wenkai Wang, Bin Li, Chao Sun, Ziwen Wang, Chunmeng Shi, Yue Zhou et al. · 2019 · Stem Cells
  57. Autophagy-related protein PIK3C3/VPS34 controls T cell metabolism and function
    Guan Yang, Wenqiang Song, Joshua Luke Postoak, Jin Chen, Jennifer Martinez, Jianhua Zhang, Lan Wu, Luc Van Kaer · 2020 · Autophagy
  58. TGF‑β1‑induced autophagy activates hepatic stellate cells via the ERK and JNK signaling pathways
    Jing Zhang, Na Jiang, Ping Jian, Lieming Xu · 2020 · International Journal of Molecular Medicine
  59. Autophagy Activation Represses Pyroptosis through the IL-13 and JAK1/STAT1 Pathways in a Mouse Model of Moderate Traumatic Brain Injury
    Cheng Gao, Yanan Yan, Guang Chen, Tao Wang, Chengliang Luo, Mingyang Zhang, Xiping Chen, Luyang Tao · 2020 · ACS Chemical Neuroscience
  60. The evolution and ecology of benign tumors
    Justine Boutry, Sophie Tissot, Beáta Újvári, Jean‐Pascal Capp, Mathieu Giraudeau, Aurora M. Nedelcu, Frédéric Thomas A · 2021 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  61. A bioinformatics analysis, pre-clinical and clinical conception of autophagy in pancreatic cancer: Complexity and simplicity in crosstalk
    Milad Ashrafizadeh, Wei Zhang, Rongjun Zou, Gautam Sethi, Daniel J. Klionsky, Xianbin Zhang · 2023 · Pharmacological Research
  62. HPV E6/E7: insights into their regulatory role and mechanism in signaling pathways in HPV-associated tumor
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  63. Targeting the Lysosome for Cancer Therapy
    Christina G. Towers, Andrew M. Thorburn · 2017 · Cancer Discovery
  64. Autophagy Paradox of Cancer: Role, Regulation, and Duality
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  68. Autophagy in the cancer-immunity dialogue
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  71. Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
    Jing Xu, Kevin Yang, Nancy E. Go, Shane Colborne, Cally J. Ho, Elham Hosseini Beheshti, Alf Håkon Lystad, Anne Simonsen, Emma Tomlinson Guns, Gregg B. Morin et al. · 2022 · Autophagy
  72. Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy
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  73. Shikonin induces colorectal carcinoma cells apoptosis and autophagy by targeting galectin-1/JNK signaling axis
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  74. Inhalation delivery of repurposed drugs for lung cancer: Approaches, benefits and challenges
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  78. Circular RNA hsa_circ_0110389 promotes gastric cancer progression through upregulating SORT1 via sponging miR-127-5p and miR-136-5p
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  90. Colorectal cancer cells respond differentially to autophagy inhibition in vivo
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  91. UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma
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  92. Autophagy, Oxidative Stress and Cancer Development
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  94. Research Progress of Nanomedicine-Based Mild Photothermal Therapy in Tumor
    Xiang He, Shengtao Zhang, Yuhang Tian, Wen Cheng, Hui Jing · 2023 · International Journal of Nanomedicine
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  99. Insufficient radiofrequency ablation promotes proliferation of residual hepatocellular carcinoma via autophagy
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