The DOI matches its Crossref record; 187 of the 189 references it cites were found in a registry or an index, and 2 are not checked yet.
Hyaluronan: from extracellular glue to pericellular cue
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In the citing paper
“Another major component of the ECM is HA, a glycosaminoglycan (GAG) that regulates lubrication through the binding of water, and is responsible for various cellular processes related to movement and maturation.”
From Unraveling and Harnessing the Immune Response at the Cell–Biomaterial Interface for Tissue Engineering Purposes (2024) · cites this paper as [259]
In the citing paper
“Furthermore, because HASs retain the growing hyaluronan polymer while synthesizing and extruding it from the cell surface (Toole, 2004), they might act as anchor molecules for the PNN.”
From The hyaluronan and proteoglycan link proteins: Organizers of the brain extracellular matrix and key molecules for neuronal function and plasticity (2015) · cites this paper as Toole, 2004
Citations
Cites
Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219
Prospective identification of tumorigenic breast cancer cells
Al‐Hajj, M., Wicha, M. S., Benito‐Hernández, A., Morrison, S. J., & Clarke, M. F. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0530291100 · Cited by 10,579
Epithelial–mesenchymal transitions in tumour progression
Thiery, J. P. (2002) · Nature reviews. Cancer · doi:10.1038/nrc822 · Cited by 6,767
New functions for the matrix metalloproteinases in cancer progression
Egeblad, M., & Werb, Z. (2002) · Nature Reviews Cancer · doi:10.1038/nrc745 · Cited by 6,108
Multidrug resistance in cancer: role of ATP–dependent transporters
Gottesman, M. M., Fojo, T., & Bates, S. E. (2002) · Nature Reviews Cancer · doi:10.1038/nrc706 · Cited by 5,536
Dissemination and growth of cancer cells in metastatic sites
Chambers, A. F., Groom, A. C., & MacDonald, I. C. (2002) · Nature reviews. Cancer · doi:10.1038/nrc865 · Cited by 4,018
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
Nelson, W. J., & Nusse, R. (2004) · Science · doi:10.1126/science.1094291 · Cited by 2,537
CD44: From adhesion molecules to signalling regulators
Ponta, H., Sherman, L. S., & Herrlich, P. A. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1004 · Cited by 2,458
CD44 is the principal cell surface receptor for hyaluronate
Aruffo, A. A., Stamenkovic, I., Melnick, M., Underhill, C. B., & Seed, B. (1990) · Cell · doi:10.1016/0092-8674(90)90694-a · Cited by 2,439
Bissell, M. J., & Radisky, D. (2001) · Nature Reviews Cancer · doi:10.1038/35094059 · Cited by 2,180
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Lee, H., Dellatore, S. M., Miller, W. M., & Messersmith, P. B. (2007) · Science · doi:10.1126/science.1147241 · Cited by 10,965
Provenzano, P. P., Cuevas, C., Chang, A. E., Goel, V. K., Von Hoff, D. D., & Hingorani, S. R. (2012) · Cancer Cell · doi:10.1016/j.ccr.2012.01.007 · Cited by 2,195
Hyaluronic Acid Hydrogels for Biomedical Applications
Burdick, J. A., & Prestwich, G. D. (2011) · Advanced Materials · doi:10.1002/adma.201003963 · Cited by 2,150
Genetics and biology of pancreatic ductal adenocarcinomaPreprint
Hezel, A. F., Kimmelman, A. C., Stanger, B. Z., Bardeesy, N. M., & DePinho, R. A. (2006) · Genes & Development · doi:10.1101/gad.1415606 · Cited by 1,611
The sweet and sour of cancer: glycans as novel therapeutic targets
Fuster, M. M., & Esko, J. D. (2005) · Nature reviews. Cancer · doi:10.1038/nrc1649 · Cited by 1,389
Metadata
- Authors
- Toole, B. P.
- Affiliations
- Medical University of South Carolina (US)
- Corresponding author
- Toole, Bryan P.
- ORCID
- Toole, Bryan P.
- Venue
- Nature Reviews Cancer
- Published
- 2004-07
- Volume
- 4
- Issue
- 7
- Pages
- 528-539
- ISSN
- 1474-175X (ISSN-L)
- 1474-1768
- OpenAlex
- W2089753996
- Semantic Scholar
- 3488563c03cedbae83c9c1d8423aeb0c6b33a4a3
- Cited by
- 2,125
- References
- 188
- Citations by year
- 2026: 61 · 2025: 78 · 2024: 81 · 2023: 97 · 2022: 93 · 2021: 129 · 2020: 120 · 2019: 120 · 2018: 116 · 2017: 112 · 2016: 150 · 2015: 130 · 2014: 126 · 2013: 103 · 2012: 99
- FWCI
- 3.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature reviews. Cancer (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Proteoglycans and glycosaminoglycans research
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Keywords
- hyaluronic acid, extracellular matrix, cell microenvironment, tumor microenvironment, embryonic development, wound healing, inflammation, carcinogenesis, cancer therapy
- MeSH terms
- Adult, Animals, Cell Survival, Connective Tissue, Extracellular Matrix, Embryonic and Fetal Development, Forecasting, Humans, Hyaluronic Acid, Hyaluronoglucosaminidase, Inflammation, Joints, Neoplasm Invasiveness, Neoplasm Metastasis, Neoplasms, Neovascularization, Pathologic, Ultrasonography, Wound Healing, Signal Transduction, Drug Resistance, Multiple, Hyaluronan Receptors, Drug Resistance, Neoplasm, Xenograft Model Antitumor Assays
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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