Cancer nanotechnology: opportunities and challenges

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1. A pH-responsive platform combining chemodynamic therapy with limotherapy for simultaneous bioimaging and synergistic cancer therapy
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2. Atomically Precise Au42 Nanorods with Longitudinal Excitons for an Intense Photothermal Effect
   Yingwei Li, Yongbo Song, Xinwen Zhang, Tongyu Liu, Tingting Xu, He Wang, De‐en Jiang, Rongchao M. Jin · 2022 · Journal of the American Chemical Society
3. The effect of primary particle size on biodistribution of inhaled gold nano-agglomerates
   Suresh K. Balasubramanian, Kay-Wee Poh, Choon Nam Ong, Wolfgang G. Kreyling, Wei‐Yi Ong, Liya E. Yu · 2013 · Biomaterials
4. Biomolecule-Assisted Synthesis of Water-Soluble Silver Nanoparticles and Their Biomedical Applications
   Qingzhi Wu, Huaqiang Cao, Qiuying Luan, Jiyong Zhang, Zhao Wang, Jamie H. Warner, Andrew A. R. Watt · 2008 · Inorganic Chemistry
5. Poly(lactic acid)-based particulate systems are promising tools for immune modulation
   Carina Peres, Ana I. Matos, João Conniot, Vanessa Sainz, Eva Zupančič, Joana M. Silva, Luís Graça, Rogério S. Gaspar, Véronique Préat A, Helena F. Florindo · 2016 · Acta Biomaterialia
6. Methotrexate–Camptothecin Prodrug Nanoassemblies as a Versatile Nanoplatform for Biomodal Imaging-Guided Self-Active Targeted and Synergistic Chemotherapy
   Yang Li, Jinyan Lin, Jinyuan Ma, Liang Song, Huirong Lin, Bowen Tang, Dengyue Chen, Guanghao Su, Shefang Ye, Xuan Zhu et al. · 2017 · ACS Applied Materials & Interfaces
7. Cell up-take control of gold nanoparticles functionalized with a thermoresponsive polymer
   Stefano Salmaso, Paolo Caliceti, Vincenzo Amendola, Moreno Meneghetti, Johannes Pall Magnusson, George Pasparakis, Cameron Alexander · 2009 · Journal of Materials Chemistry
8. Core-shell silica nanoparticles as fluorescent labels for nanomedicine
   Jinhyang Choi, Andrew Burns, Rebecca M. Williams, Zongziang Zhou, Andrea Flesken‐Nikitin, Warren R. Zipfel, Ulrich B. Wiesner, Alexander Yu. Nikitin · 2007 · Journal of Biomedical Optics
9. Biomimetic High Density Lipoprotein Nanoparticles For Nucleic Acid Delivery
   Kaylin Marie McMahon, R. Kannan Mutharasan, Sushant Tripathy, Dorina Veliceasa, Mariana Bobeica, Dale K. Shumaker, Andrea J. Luthi, Brian T. Helfand, Hossein Ardehali, Chad Alexander Mirkin et al. · 2011 · Nano Letters
10. Electrostatic Co‐Assembly of Iron Oxide Nanoparticles and Polymers: Towards the Generation of Highly Persistent Superparamagnetic Nanorods
    Jérôme Fresnais, Jean‐François Berret, Bruno Frka‐Petesic, Olivier Sandre, R. Perzynski · 2008 · Advanced Materials
11. Electrochemiluminescent Quenching of Quantum Dots for Ultrasensitive Immunoassay through Oxygen Reduction Catalyzed by Nitrogen-Doped Graphene-Supported Hemin
    Shengyuan Deng, Jianping Lei, Yin Hui Huang, Yan Cheng, Huangxian Ju · 2013 · Analytical Chemistry
12. Smart Drug-Delivery Systems for Cancer Nanotherapy
    Paola Sánchez‐Moreno, Juan Luis Ortega-Vinuesa, José Manuel Peula-García, Juan Antonio Marchal, Houría Boulaiz · 2016 · Current Drug Targets
13. Control of Ultrasmall Sub-10 nm Ligand-Functionalized Fluorescent Core–Shell Silica Nanoparticle Growth in Water
    Kai Ma, Carlie Mendoza, Margaret A. Hanson, Ulrike Werner‐Zwanziger, Josef W. Zwanziger, Ulrich B. Wiesner · 2015 · Chemistry of Materials
14. Lipid polymer hybrid nanoparticles as potent vehicles for drug delivery in cancer therapeutics
    Shama Parveen, Pratishtha Gupta, Saurabh Kumar, Monisha Banerjee · 2023 · Medicine in Drug Discovery
15. Development and therapeutic applications of advanced biomaterials
    Jeffrey M. Karp, Róbert Langer · 2007 · Current Opinion in Biotechnology
16. Polymer therapeutics—polymers as drugs, drug and protein conjugates and gene delivery systems: Past, present and future opportunities
    Ruth Duncan, Helmut Ringsdorf, Ronit Satchi‐Fainaro · 2006 · Journal of drug targeting
17. Toxicity assessment of manganese oxide micro and nanoparticles in Wistar rats after 28 days of repeated oral exposure
    Shailendra Pratap Singh, Monika Kumari, Srinivas Indu Kumari, Mohammed Fazlur Rahman, Mohammed Mahboob, Paramjit Grover · 2013 · Journal of Applied Toxicology
18. E‐Selectin‐Targeted Porous Silicon Particle for Nanoparticle Delivery to the Bone Marrow
    Aman P. Mann, Takemi Tanaka, Anoma Somasunderam, Xuewu Liu, David G. Gorenstein, Mauro Ferrari B · 2011 · Advanced Materials
19. Nanoparticle-based drug delivery systems: promising approaches against infections
    Shweta Ranghar, Parul Sirohi, Pritam Verma, Vishnu Kumar Agarwal · 2013 · Brazilian Archives of Biology and Technology
20. Protein Nanocapsules Containing Doxorubicin as a pH‐Responsive Delivery System
    Dongmei Ren, Felix Kratz, Szu‐Wen Wang · 2011 · Small
21. Organic Dots with Aggregation-Induced Emission (AIE Dots) Characteristics for Dual-Color Cell Tracing
    Kai Li, Zhenshu Zhu, Pingqiang Cai, Rongrong Liu, Nikodem Tomczak, Dan Ding, Jie Liu, Wei Qin, Zujin Zhao, Yong Hu et al. · 2013 · Chemistry of Materials
22. Green Synthesis of Gold Nanoparticles Using Sumac Aqueous Extract and Their Antioxidant Activity
    Hoda Shabestarian, Masoud Homayouni Tabrizi, Mozhgan Soltani, Farideh Namvar, Susan Azizi, Rosfarizan Mohamad, Hanieh Shabestarian · 2016 · Materials Research
23. Drug-loaded and superparamagnetic iron oxide nanoparticle surface-embedded amphiphilic block copolymer micelles for integrated chemotherapeutic drug delivery and MR imaging
    Hu, Jinming, Qian, Yinfeng, Wang, Xiaofeng, Liu, Tao, Liu, Shiyong · 2012 · Langmuir
24. Anti-fouling magnetic nanoparticles for siRNA delivery
    Cyrille Andre Boyer, Priyanto Priyanto, Thomas Paul Davis, Dakrong Pissuwan, Volga Bulmuş, Maria Kavallaris, Wey Yang Teoh, Rose Amal, Matt Carroll, Robert C. Woodward et al. · 2009 · Journal of Materials Chemistry
25. In vitro assessment of engineered nanomaterials using a hepatocyte cell line: cytotoxicity, pro-inflammatory cytokines and functional markers
    Ali Kermanizadeh, Giulio Pojana, Birgit K. Gaiser, Renie K. Birkedal, Dagmar Bilaničová, Håkan Wallin, Keld Alstrup Jensen, Börje Sellergren, Gary R. Hutchison, Antonio Marcomini et al. · 2012 · Nanotoxicology
26. Chlorotoxin-Conjugated Multifunctional Dendrimers Labeled with Radionuclide 131I for Single Photon Emission Computed Tomography Imaging and Radiotherapy of Gliomas
    Lingzhou Zhao, Jingyi Zhu, Yongjun Cheng, Zhijuan Xiong, Yueqin Tang, Lilei Guo, Xiangyang Shi, Jinhua Zhao · 2015 · ACS Applied Materials & Interfaces
27. A protein@metal–organic framework nanocomposite for pH-triggered anticancer drug delivery
    Zuozhong Liang, Zhiyuan Yang, Haitao Yuan, Chun Wang, Jing Qi, Kaiqiang Liu, Rui Cao, Haoquan Zheng · 2018 · Dalton Transactions
28. Pulmonary delivery by exploiting doxorubicin and cisplatin co-loaded nanoparticles for metastatic lung cancer therapy
    Caina Xu, Yanbing Wang, Zhaopei Guo, Jie Chen, Lin Lın, Jiayan Wu, Huayu Tian, Xuesi Chen · 2018 · Journal of Controlled Release
29. Cyclodextrin-based host-guest complexes loaded with regorafenib for colorectal cancer treatment
    Hongzhen Bai, Jianwei Wang, Chi Uyen Phan, Qi Chen, Xiu-Rong Hu, Guoqiang Shao, Jun Zhou, Lihua Lai, Guping Tang · 2021 · Nature Communications
30. Multi-functional liposomes having temperature-triggered release and magnetic resonance imaging for tumor-specific chemotherapy
    Kenji Kono, Seiji Nakashima, Daisuke Kokuryo, Ichio Aoki, Hiroaki Shimomoto, Sadahito Aoshima, Kazuo Maruyama, Eiji Yuba, Chie Kojima, Atsushi Harada et al. · 2010 · Biomaterials
31. Gold Nano-Popcorn Attached SWCNT Hybrid Nanomaterial for Targeted Diagnosis and Photothermal Therapy of Human Breast Cancer Cells
    Lule Beqa, Zhen Fan, Anant Kumar Singh, Dulal Senapati, Paresh Chandra Ray · 2011 · ACS Applied Materials & Interfaces
32. Microfluidics-mediated assembly of functional nanoparticles for cancer-related pharmaceutical applications
    Qiang Feng, Jiashu Sun, Xingyu Jiang · 2016 · Nanoscale
33. Novel docetaxel chitosan-coated PLGA/PCL nanoparticles with magnified cytotoxicity and bioavailability
    Mohammad M. Badran, Abdullah H. Alomrani, Gamaleldin I. Harisa, Abdelkader Elbadawy Ashour, Ashok Kumar, Alaa Eldeen B. Yassin · 2018 · Biomedicine & Pharmacotherapy
34. Fabrication, characterization and cytotoxicity studies of ionically cross-linked docetaxel loaded chitosan nanoparticles
    Ankit Jain, Kanika Thakur, Gajanand Sharma, Preeti Kush, Upendra Kumar Jain · 2015 · Carbohydrate Polymers
35. Advanced Nanomaterials in Multimodal Imaging: Design, Functionalization, and Biomedical Applications
    Zhe Liu, Fabian M. Kiessling, J. Gätjens · 2010 · Journal of Nanomaterials
36. Enhanced reduction in cell viability by hyperthermia induced by magnetic nanoparticles
    Madeline Torres‐Lugo, Hector L. Rodriguez, Magda Latorre‐Esteves, Janet Méndez, Orlando Soto, Ana R. Rodriguez, Carlos Rinaldi · 2011 · International Journal of Nanomedicine
37. Lapatinib/Paclitaxel polyelectrolyte nanocapsules for overcoming multidrug resistance in ovarian cancer
    Daniele Vergara, Claudia Bellomo, Xingcai Zhang, Viviana Vergaro, Andrea Tinelli, Vito Lorusso, R. Rinaldi, YURI M. LVOV, Stefano Leporatti, Michele Maffia · 2011 · Nanomedicine Nanotechnology Biology and Medicine
38. Engineered PLGA Nanoparticles: An Emerging Delivery Tool in Cancer Therapeutics
    Amit Jain, Manasmita Das, Nitin Kumar Swarnakar, Sanyog Jain · 2011 · Critical Reviews in Therapeutic Drug Carrier Systems
39. Synthesis of Fluorine-18 Functionalized Nanoparticles for use as in vivo Molecular Imaging Agents
    John B. Matson, Robert Howard Grubbs · 2008 · Journal of the American Chemical Society
40. Size and ζ-Potential Measurement of Silica Nanoparticles in Serum Using Tunable Resistive Pulse Sensing
    Aneta E. Sikora, Alexander G. Shard, Caterina Minelli · 2016 · Langmuir
41. Peptide-functionalized, -assembled and -loaded nanoparticles in cancer therapy
    Jingyuan Dai, Milad Ashrafizadeh, Amir Reza Aref, Gautam Sethi, Yavuz Nuri Ertaş · 2024 · Drug Discovery Today
42. The incorporation of daunorubicin in cancer cells through the use of titanium dioxide whiskers
    Qingning Li, Xuemei Wang, Xiaohua Lü, Honger Tian, Hui Jiang, Gang Lv, Dadong Guo, Chunhui Wu, Baoan Chen · 2009 · Biomaterials
43. Circulating Nucleic Acids in Plasma and Serum
    Peter Brian Gahan, R. Swaminathan · 2008 · Annals of the New York Academy of Sciences
44. The margination propensity of spherical particles for vascular targeting in the microcirculation
    Francesco Gentile, Antonio Curcio, Ciro Indolfi, Mauro Ferrari B, Paolo Decuzzi · 2008 · Journal of Nanobiotechnology
45. Synthetic nanoparticles camouflaged with biomimetic erythrocyte membranes for reduced reticuloendothelial system uptake
    Lang Rao, Junhua Xu, Bo Cai, Huiqin Liu, Ming Li, Yan Jia, Liang Xiao, Shishang Guo, Wei Liu, Xingzhong Zhao · 2016 · Nanotechnology
46. Application of iron oxide nanoparticles in glioma imaging and therapy: from bench to bedside
    Heng Liu, Jun Zhang, Xiao Chen, Xuesong Du, Jinlong Zhang, Gang Liu, Weiguo Zhang · 2016 · Nanoscale
47. Adsorption of Plasma Proteins onto PEGylated Lipid Bilayers: The Effect of PEG Size and Grafting Density
    Hwankyu Lee, Ronald G. Larson · 2016 · Biomacromolecules
48. Canine parvovirus-like particles, a novel nanomaterial for tumor targeting
    Pratik Narendra Pratap Singh, Giuseppe Destito, Anette Schneemann, Marianne Manchester · 2006 · Journal of Nanobiotechnology
49. Graphene oxide used as a carrier for adriamycin can reverse drug resistance in breast cancer cells
    Jing Wu, Yinsong Wang, Xiaoying Yang, Yuan-yuan Liu, Jinrong Yang, Rui Yang, Ning Zhang · 2012 · Nanotechnology
50. Nanoparticle Delivery of Natural Products in the Prevention and Treatment of Cancers: Current Status and Future Prospects
    Dhruba Jyoti Bharali, Imtiaz Ahmad Siddiqui, Vaqar Mustafa Adhami, Jean Christopher Chamcheu, Abdullah M. Aldahmash, Hasan Mukhtar, Shaker A. Mousa · 2011 · Cancers
51. Photosensitizer-doped conjugated polymer nanoparticles for simultaneous two-photon imaging and two-photon photodynamic therapy in living cells
    Xiaoqin Shen, Lin Li, Hao Wu, Shao Qin Yao, Qing‐Hua Xu · 2011 · Nanoscale
52. Nanocarriers for Anticancer Drugs - New Trends in Nanomedicine
    Jana Drbohlavová, Jana Chomoucká, Vojtěch Adam, Markéta Ryvolová, Tomáš Eckschlager, Jaromír Hubálek, René Kizek · 2013 · Current Drug Metabolism
53. Multifunctional Biodegradable Polyacrylamide Nanocarriers for Cancer Theranostics—A “See and Treat” Strategy
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54. Placenta-specific drug delivery by trophoblast-targeted nanoparticles in mice
    Baozhen Zhang, Lunbo Tan, Yan Yu, Baobei Wang, Zhilong Chen, Jinyu Han, Mengxia Li, Jie Chen, Tianxia Xiao, Balamurali Krishna Ambati et al. · 2018 · Theranostics
55. Photodynamic‐Chemodynamic Cascade Reactions for Efficient Drug Delivery and Enhanced Combination Therapy
    Sheng Wang, Guocan Yu, Weijing Yang, Zhantong Wang, Orit Jacobson, Rui Tian, Hongzhang Deng, Lisen Lin, Xiaoyuan Shawn Chen · 2021 · Advanced Science
56. Enhanced x-ray irradiation-induced cancer cell damage by gold nanoparticles treated by a new synthesis method of polyethylene glycol modification
    Chi-Jen Liu, Changhai Wang, Chia‐Chi Chien, Tsung-Yeh Yang, Shin‐Tai Chen, Wei-Hua Leng, Cheng-Feng Lee, Kuen-Ho Lee, Y. Hwu, Yao-Chang Lee et al. · 2008 · Nanotechnology
57. In vivo tumor targeting and radionuclide imaging with self-assembled nanoparticles: Mechanisms, key factors, and their implications
    Yong Woo Cho, Soo Ah Park, Tae Hee Han, Dai Hyun Son, Ji Sun Park, Seung Jun Oh, Dae Hyuk Moon, Kyung-Ja Cho, Cheol-Hee Ahn, Youngro Byun et al. · 2006 · Biomaterials
58. Nanochemoprevention: Sustained Release of Bioactive Food Components for Cancer Prevention
    Imtiaz Ahmad Siddiqui, Vaqar Mustafa Adhami, Nihal Ahmad, Hasan Mukhtar · 2010 · Nutrition and Cancer
59. Multiresponse Strategies To Modulate Burst Degradation and Release from Nanoparticles
    Jagadis Sankaranarayanan, E. Mahmoud, Gloria Kim, José M. Morachis, Adah Almutairi · 2010 · ACS Nano
60. Microfluidics and cancer: are we there yet?
    Zhuo Zhang, Sunitha Nagrath · 2013 · Biomedical Microdevices
61. pH-sensitive strontium carbonate nanoparticles as new anticancer vehicles for controlled etoposide release
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62. Tumor-Targeted Drug Delivery with Aptamers
    Yi Zhang, Hao Hong, Weibo Cai · 2011 · Current Medicinal Chemistry
63. Shrinkage of pegylated and non-pegylated liposomes in serum
    Joy Wolfram, Krishna Avtar Suri, Yong Ping Yang, Jianliang Shen, Christian Celia, Massimo Fresta, Yuliang Zhao, Haifa Shen, Mauro Ferrari B · 2013 · Colloids and Surfaces B Biointerfaces
64. Intracellular Distribution of TiO2−DNA Oligonucleotide Nanoconjugates Directed to Nucleolus and Mitochondria Indicates Sequence Specificity
    Tatjana Paunesku, Stefan Vogt, Barry Chi Hong Lai, Jorg M. Maser, Nataša Stojićević, Kenneth T. Thurn, Clodia Osipo, Hong Shi Liu, Dan G. Legnini, Zhou Wang et al. · 2007 · Nano Letters
65. Injectable in Situ Forming Hydrogels of Thermosensitive Polypyrrole Nanoplatforms for Precisely Synergistic Photothermo-Chemotherapy
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66. Nanoparticles for improving cancer diagnosis
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67. Glycyrrhetinic acid-modified poly(ethylene glycol)–b-poly(γ-benzyl l-glutamate) micelles for liver targeting therapy
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68. Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles
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69. Morphologies and functionalities of polymeric nanocarriers as chemical tools for drug delivery: A review
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70. Analyzing the mechanisms of iron oxide nanoparticles interactions with cells: A road from failure to success in clinical applications
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71. Tailored Magnetic Nanoparticles for Direct and Sensitive Detection of Biomolecules in Biological Samples
    Andrea Fornara, Petter Johansson, Karolina Petersson, Stefan Gustafsson, Jian Qin, Eva Olsson, Dag Ilver, Anatol Krozer, Mamoun A. Muhammed, Christer Johansson · 2008 · Nano Letters
72. Bioactive and Therapeutic ROMP Polymers
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73. MMP-2 responsive polymeric micelles for cancer-targeted intracellular drug delivery
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74. Targeted Cytosolic Delivery of Cell-Impermeable Compounds by Nanoparticle-Mediated, Light-Triggered Endosome Disruption
    Sébastien Febvay, Davide M. Marini, Angela M. Belcher, David E. Clapham · 2010 · Nano Letters
75. Schiff based injectable hydrogel for in situ pH-triggered delivery of doxorubicin for breast tumor treatment
    Junbin Shi, Wang Guo-bao, Hongli Chen, Wen Zhong, Xiaozhong Qiu, Malcolm M. Q. Xing · 2014 · Polymer Chemistry
76. Template synthesis of multifunctional nanotubes for controlled release
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77. Co-delivery of doxorubicin and siRNA using octreotide-conjugated gold nanorods for targeted neuroendocrine cancer therapy
    Yuling Xiao, Renata Jaskula‐Sztul, Alireza Javadi, Wenjin Xu, Jacob G. Eide, Ajitha Dammalapati, Muthusamy Kunnimalaiyaan, Herbert Chen, Shaoqin Gong · 2012 · Nanoscale
78. Dendrimer space concept for innovative nanomedicine: A futuristic vision for medicinal chemistry
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79. Nanoparticle accumulation and transcytosis in brain endothelial cell layers
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80. Magnetic nanoparticles: preparation methods, applications in cancer diagnosis and cancer therapy
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81. Tumour-specific PI3K inhibition via nanoparticle-targeted delivery in head and neck squamous cell carcinoma
    Aviram Mizrachi, Yosi Shamay, Janki Shah, Samuel Brook, Joanne Soong, Vinagolu K. Rajasekhar, John Laurence Humm, John H. Healey, Simon N. Powell, Jose M Baselga et al. · 2017 · Nature Communications
82. In vivo magnetic nanoparticle hyperthermia: a review on preclinical studies, low-field nano-heaters, noninvasive thermometry and computer simulations for treatment planning
    Harley F. Rodrigues, Gustavo Capistrano, Andris Figueiroa Bakuzis · 2020 · International Journal of Hyperthermia
83. Nanomedicine: promises and challenges for the future of public health
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84. Challenges, expectations and limits for nanoparticles-based therapeutics in cancer: A focus on nano-albumin-bound drugs
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85. Gadolinium metallofullerenol nanoparticles inhibit cancer metastasis through matrix metalloproteinase inhibition: imprisoning instead of poisoning cancer cells
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86. Lipid Bilayer Curvature and Pore Formation Induced by Charged Linear Polymers and Dendrimers: The Effect of Molecular Shape
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87. Magnetic Biotransport: Analysis and Applications
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88. Combination of chemotherapy and photodynamic therapy using graphene oxide as drug delivery system
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89. Polymeric nanoparticle system to target activated microglia/macrophages in spinal cord injury
    Simonetta Papa, Raffaele Ferrari, Massimiliano De Paola, Filippo Rossi, Alessandro Mariani, Ilaria Caron, Eliana Sammali, Marco Peviani, Valentina Dell’Oro, Claudio Colombo et al. · 2013 · Journal of Controlled Release
90. Nanobody — Shell functionalized thermosensitive core-crosslinked polymeric micelles for active drug targeting
    Marina Talelli, Cristianne J.F. Rijcken, Sabrina Oliveira, Roy van der Meel, Paul M.P. van Bergen en Henegouwen, Twan Lammers, Cornelus F. van Nostrum, Gert Storm, Wim E. Hennink · 2011 · Journal of Controlled Release
91. Influence of Nanotoxicity on Human Health and Environment: The Alternative Strategies
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92. Nanovector therapeutics
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93. Zwitterionic phosphorylcholine as a better ligand for gold nanorods cell uptake and selective photothermal ablation of cancer cells
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94. Ceramic nanoparticles: Recompense, cellular uptake and toxicity concerns
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95. Graphene Oxide Noncovalent Photosensitizer and Its Anticancer Activity In Vitro
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96. Multiplex Immunosensor Arrays for Electrochemical Detection of Cancer Biomarker Proteins
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97. Biomimetic carriers mimicking leukocyte plasma membrane to increase tumor vasculature permeability
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98. “One-for-All”-Type, Biodegradable Prussian Blue/Manganese Dioxide Hybrid Nanocrystal for Trimodal Imaging-Guided Photothermal Therapy and Oxygen Regulation of Breast Cancer
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99. Cancer nanotechnology: Enhancing tumor cell response to chemotherapy for hepatocellular carcinoma therapy
    Yongbing Sun, Wen Ma, Yuanyuan Yang, Mengxue He, Aimin Li, Lei Bai, Bin Yu, Zhiqiang Yu · 2019 · Asian Journal of Pharmaceutical Sciences
100. Silicon Nanoparticles as Hyperpolarized Magnetic Resonance Imaging Agents
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