A decade of exploring the cancer epigenome—biological and translational implications

Baylin, Stephen B., Jones, Peter A.·2011·Nature Reviews Cancer

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Items 601–700 of 1,001

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  2. Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma
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  3. Epigenetic modulation in cancer immunotherapy
    Stuart J. Gallagher, Elena Shklovskaya, Peter Hersey · 2017 · Current Opinion in Pharmacology
  4. Methylation patterns in serum DNA for early identification of disseminated breast cancer
    Martin Widschwendter, Iona Evans, Allison Jones, Shohreh Ghazali, Daniel Reisel, Andy Ryan, Aleksandra Gentry‐Maharaj, Michal Zikán, David Cibula, Johannes Eichner et al. · 2017 · Genome Medicine
  5. Clinical, Pathological, and Molecular Characteristics of CpG Island Methylator Phenotype in Colorectal Cancer: A Systematic Review and Meta-analysis
    Shailesh Advani, Pragati Gole Advani, Stacia M. DeSantis, Derek W. Brown, Helena M. VonVille, Michael S. Lam, Jonathan M. Loree, Amir Mehrvarz Sarshekeh, Jan Bressler, David S. López et al. · 2018 · Translational Oncology
  6. Melissa: Bayesian clustering and imputation of single-cell methylomes
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    AIFEG, Nora Sahnane, Francesca Magnoli, Barbara Bernasconi, Maria Grazia Tibiletti, Chiara Romualdi, Monica Pedroni, Maurizio Ponz de Leòn, Giulia Magnani, Luca Reggiani Bonetti et al. · 2015 · Clinical Epigenetics
  8. Intratumor heterogeneity in epigenetic patterns
    Yassen Assenov, David Brocks, Clarissa Gerhäuser · 2018 · Seminars in Cancer Biology
  9. Hyper-methylation of ABCG1 as an epigenetics biomarker in non-small cell lung cancer
    Thi-Oanh Tran, Luu Ho Thanh Lam, Nguyen Quoc Khanh Le · 2023 · Functional & Integrative Genomics
  10. Progress in epigenetic histone modification analysis by mass spectrometry for clinical investigations
    Özlem Önder, Simone Sidoli, Martin P Carroll, Benjamin Aaron Garcia · 2015 · Expert Review of Proteomics
  11. Epigenetic mechanisms and therapeutic targets of chemotherapy resistance in epithelial ovarian cancer
    Jane Borley, Robert Eldon Brown · 2015 · Annals of Medicine
  12. Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer
    Yuting Chen, Charles E. Breeze, Shao Zhen, Stephan Beck, Andrew Erich Teschendorff · 2016 · Epigenetics & Chromatin
  13. Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells
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  14. Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases
    Renate M. Hoogeveen, Matthias Nahrendorf, Niels Peter Riksen, Mihai Gheorghe Netea, Menno P.J. de Winther, Esther Lutgens, Børge Grønne Nordestgaard, Michel Neidhart, Erik S.G. Stroes, Alberico Luigi Catapano et al. · 2017 · European Heart Journal
  15. Integrative Epigenetic Analysis Reveals Therapeutic Targets to the DNA Methyltransferase Inhibitor Guadecitabine (SGI‐110) in Hepatocellular Carcinoma
    Minmin Liu, Lian Zhang, Hongtao Li, Toshinori Hinoue, Wanding Zhou, Hitoshi Ohtani, Anthony B. El-Khoueiry, John R. Daniels, Casey Lee O'Connell, Tanya Barauskas Dorff et al. · 2018 · Hepatology
  16. Histone Methyltransferase SETDB1 Promotes the Progression of Colorectal Cancer by Inhibiting the Expression of TP53
    Ke-Li Chen, Fengjiao Zhang, Jie Ding, Yonghao Liang, Zetao Zhan, Yizhi Zhan, Longhua Chen, Yi� Ding · 2017 · Journal of Cancer
  17. Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasiveness
    Gi-Cheon Kim, Ho‐Keun Kwon, Choong‐Gu Lee, Ravi Prakash Verma, Dipayan Rudra, Taemook Kim, Keunsoo Kang, Jong Hee Nam, Young Kim, Sin‐Hyeog Im · 2018 · Oncogenesis
  18. Transcriptional Selectivity of Epigenetic Therapy in Cancer
    Takahiro Sato, Matteo Cesaroni, Woonbok Chung, Shoghag B. Panjarian, Anthony Tran, Jozef Madžo, Yasuyuki Okamoto, Hanghang Zhang, Xiaowei Chen, Jaroslav Jelı́nek et al. · 2016 · Cancer Research
  19. Genome-wide DNA methylation profile identified a unique set of differentially methylated immune genes in oral squamous cell carcinoma patients in India
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  20. Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell Carcinoma
    Ali Mehdi, Yasser Riazalhosseini · 2017 · International Journal of Molecular Sciences
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  22. Differential Methylation and Acetylation as the Epigenetic Basis of Resveratrol’s Anticancer Activity
    Mohd Farhan, Mohammad Fahad Ullah, Mohd Faisal, Ammad Ahmad Farooqı, Uteuliyev Yerzhan Sabitaliyevich, Bernhard Biersack, Aamir Ahmad · 2019 · Medicines
  23. Small Molecule Control of Chromatin Remodeling
    Aidan Finley, Robert A. Copeland · 2014 · Chemistry & Biology
  24. Evodiamine-inspired dual inhibitors of histone deacetylase 1 (HDAC1) and topoisomerase 2 (TOP2) with potent antitumor activity
    Yahui Huang, Shuqiang Chen, Shanchao Wu, Guoqiang Dong, Chunquan Sheng · 2019 · Acta Pharmaceutica Sinica B
  25. Zebularine elevates STING expression and enhances cGAMP cancer immunotherapy in mice
    Junzhong Lai, Yajuan Fu, Shuoran Tian, Shanlu Huang, Xuan Luo, Lili Lin, Xing Zhang, Hanze Wang, Zhang Lin, Heng Zhao et al. · 2021 · Molecular Therapy
  26. Epigenetics and environment in breast cancer: New paradigms for anti-cancer therapies
    Chitra Thakur, Yiran Qiu, Yao Shi Fu, Zhuoyue Bi, Wenxuan Zhang, Haoyan Ji, Fei Chen · 2022 · Frontiers in Oncology
  27. DNA Methylation Profiles at Precancerous Stages Associated with Recurrence of Lung Adenocarcinoma
    Takashi Sato, Eri Arai, Takashi Kohno, Koji Tsuta, Shun-ichi Watanabe, Kenzo Soejima, Tomoko Betsuyaku, Yae Kanai · 2013 · PLoS ONE
  28. Quantification of 5-methylcytosine, 5-hydroxymethylcytosine and 5-carboxylcytosine from the blood of cancer patients by an enzyme-based immunoassay
    Basudev Chowdhury, Il‐Hoon Cho, Noah M. Hahn, Joseph Irudayaraj · 2014 · Analytica Chimica Acta
  29. A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival
    Shahzia Anjum, Evangelia-O Fourkala, Michal Zikán, Andrew Wong, Aleksandra Gentry‐Maharaj, Allison Jones, Rebecca Hardy, David Cibula, Diana J. Kuh, Ian J. Jacobs et al. · 2014 · Genome Medicine
  30. A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2′-Deoxycytidine
    Benjamin R. Leadem, Ioannis Kagiampakis, CATHERINE A. WILSON, Tommy K. Cheung, David P. Arnott, Patrick Trojer, Marie Classon, Hariharan Easwaran, Stephen B. Baylin · 2017 · Cancer Research
  31. The role of epigenetic therapies in colorectal cancer
    Marina Baretti, Nilofer Saba Azad · 2018 · Current Problems in Cancer
  32. The Crosstalk Between Epigenetic Mechanisms and Alternative RNA Processing Regulation
    Jian Zhang, Yizhe Zhang, Jing Jiang, Cheng‐Guo Duan · 2020 · Frontiers in Genetics
  33. TET-Mediated Epigenetic Regulation in Immune Cell Development and Disease
    Nikolas J. Tsiouplis, David Wesley Bailey, Lilly F. Chiou, Fiona Jane Wissink, Ageliki Tsagaratou · 2021 · Frontiers in Cell and Developmental Biology
  34. Cell-free DNA methylation markers for differential diagnosis of hepatocellular carcinoma
    Biyuan Luo, Fang Ma, Hao Liu, Jixiong Hu, Le Rao, Chunying Liu, Yongfang Jiang, Shuyu Kuang-Zeng, Xuan Lin, Chenyang Wang et al. · 2022 · BMC Medicine
  35. Methylated DNA Immunoprecipitation and High-Throughput Sequencing (MeDIP-seq) Using Low Amounts of Genomic DNA
    Mingtao Zhao, Jeffrey J. Whyte, Garrett M. Hopkins, Mark D. Kirk, Randall S. Prather · 2014 · Cellular Reprogramming
  36. Functional proteomics of the epigenetic regulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics for translational medicine
    Masaru Katoh · 2015 · Expert Review of Proteomics
  37. Mathematical model of adult stem cell regeneration with cross-talk between genetic and epigenetic regulation
    Jinzhi Lei, Simon A. Levin, Qing Hua Nie · 2014 · Proceedings of the National Academy of Sciences
  38. Anticancer Natural Compounds as Epigenetic Modulators of Gene Expression
    Edward A. Ratovitski · 2017 · Current Genomics
  39. A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from the TACL consortium
    Weili Sun, Timothy Junius Triche, Jemily Malvar, Paul S. Gaynon, Richard Sposto, Xiaojing Yang, Henrique Neves da Silva Bittencourt, Andrew E. Place, Yoav H. Messinger, Chris Fraser et al. · 2018 · Blood
  40. Rewiring of cisplatin-resistant bladder cancer cells through epigenetic regulation of genes involved in amino acid metabolism
    Austin Yeon, Sungyong You, Minhyung Kim, Amit Gupta, Myung Hee Park, Daniel J. Weisenberger, Gangning Liang, Jayoung Kim · 2018 · Theranostics
  41. Epigenetic Reprogramming of TGF-β Signaling in Breast Cancer
    Sudha Suriyamurthy, David A. Baker, Peter ten Dijke, Prasanna Vasudevan Iyengar · 2019 · Cancers
  42. Chemotherapy-Induced Distal Enhancers Drive Transcriptional Programs to Maintain the Chemoresistant State in Ovarian Cancer
    Stephen Shang, Jiekun Yang, Amir Anthony Jazaeri, Alexander James Duval, Turan Tufan, Natasha Lopes Fischer, Mouadh Benamar, Fadila Guessous, In-Young Lee, Robert M. Campbell et al. · 2019 · Cancer Research
  43. Deciphering DNA methylation signatures of pancreatic cancer and pancreatitis
    Francesco Natale, Maria Vivo, Geppino Falco, Tiziana Angrisano · 2019 · Clinical Epigenetics
  44. Aberrant DNA hypermethylation of SDHC: a novel mechanism of tumor development in Carney triad
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  45. Zinc Finger Readers of Methylated DNA
    Nicholas O. Hudson, Bethany A. Buck‐Koehntop · 2018 · Molecules
  46. Per- and Polyfluoroalkyl Substances, Epigenetic Age and DNA Methylation: A Cross-Sectional Study of Firefighters
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  47. Multiplex Digital Methylation‐Specific PCR for Noninvasive Screening of Lung Cancer
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  48. lnflammation-induced epigenetic switches in cancer
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  49. Epigenetics: The neglected key to minimize learning and memory deficits in Down syndrome
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  50. Discovery of an orally active subtype-selective HDAC inhibitor, chidamide, as an epigenetic modulator for cancer treatment
    Desi Pan, Qian‐Jiao Yang, Xin Fu, Song Shan, Jing-Zhong Zhu, Kun Zhang, Zhibin Li, Zhiqiang Ning, Xianping Lu · 2014 · MedChemComm
  51. F2RL3 methylation, lung cancer incidence and mortality
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  52. The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins?
    Andrea Scelfo, Andrea Piunti, Diego Pasini · 2014 · FEBS Journal
  53. Synergistic anti-breast cancer effect of a combined treatment with the methyl donorS-adenosyl methionine and the DNA methylation inhibitor 5-aza-2′-deoxycytidine
    Flora Chik, Ziv M. Machnes, Moshe Szyf A · 2013 · Carcinogenesis
  54. DNA methyltransferase inhibitors: an updated patent review (2012-2015)
    Pan Xu, Guang Hu, Cheng Luo, Zhongjie T. Liang · 2016 · Expert Opinion on Therapeutic Patents
  55. Epigenetic regulation of active Chinese herbal components for cancer prevention and treatment: A follow-up review
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  56. Epigenetic Changes in Chronic Inflammatory Diseases
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  57. Alterations of DNA methylome in human bladder cancer
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  58. Analysis of Helios gene expression and Foxp3 TSDR methylation in the newly diagnosed Rheumatoid Arthritis patients
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  59. Regulating Methylation at H3K27: A Trick or Treat for Cancer Cell Plasticity
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  60. The recently suggested intestinal cancer stem cell markerDCLK1is an epigenetic biomarker for colorectal cancer
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  61. Acute Hypersensitivity of Pluripotent Testicular Cancer-Derived Embryonal Carcinoma to Low-Dose 5-Aza Deoxycytidine Is Associated with Global DNA Damage-Associated p53 Activation, Anti-Pluripotency and DNA Demethylation
    Bijesh Kumar Biswal, Maroun J. Beyrouthy, Mary P. Hever-Jardine, David Armstrong, Craig R. Tomlinson, Brock C. Christensen, Carmen J. Marsit, Michael J. Spinella · 2012 · PLoS ONE
  62. SEPT9 and SHOX2 DNA methylation status and its utility in the diagnosis of colonic adenomas and colorectal adenocarcinomas
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  63. Genistein Prevents BRCA1 CpG Methylation and Proliferation in Human Breast Cancer Cells with Activated Aromatic Hydrocarbon Receptor
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  64. Methylation-mediated gene silencing as biomarkers of gastric cancer: A review
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  65. Reconciling Non-Genetic Plasticity with Somatic Evolution in Cancer
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  66. CBX7 suppresses urinary bladder cancer progression via modulating AKR1B10–ERK signaling
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  67. Epigenetic Dysregulations in Merkel Cell Polyomavirus-Driven Merkel Cell Carcinoma
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  71. Improving cancer immunotherapy with DNA methyltransferase inhibitors
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  73. Enzymology of Mammalian DNA Methyltransferases
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  74. LncRNA regulation: New frontiers in epigenetic solutions to drug chemoresistance
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  75. The Crossroads of Cancer Epigenetics and Immune Checkpoint Therapy
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  76. Methylomics and cancer: the current state of methylation profiling and marker development for clinical care
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  77. Chromatin modifications during repair of environmental exposure‐induced DNA damage: A potential mechanism for stable epigenetic alterations
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  78. PAX 1 / SOX 1 DNA methylation and cervical neoplasia detection: a Taiwanese Gynecologic Oncology Group ( TGOG ) study
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  80. A phase I, pharmacokinetic, and pharmacodynamic evaluation of the DNA methyltransferase inhibitor 5-fluoro-2′-deoxycytidine, administered with tetrahydrouridine
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  81. Histone modifications and a choice of variant: a language that helps the genome express itself
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  82. The Application of Genome-Wide 5-Hydroxymethylcytosine Studies in Cancer Research
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  83. Relationship between post-surgery detection of methylated circulating tumor DNA with risk of residual disease and recurrence-free survival
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  86. Arginine methylation of BRD4 by PRMT2/4 governs transcription and DNA repair
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  87. Epigenetic silencing of miR-708 enhances NF-κB signaling in chronic lymphocytic leukemia
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  88. Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents
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  89. Epigenetics and Oncology
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  90. The epigenetics of tumour initiation: cancer stem cells and their chromatin
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  91. DNA methylation intratumor heterogeneity in localized lung adenocarcinomas
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  93. S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cells
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  94. Counteraction of Oxidative Stress by Vitamin E Affects Epigenetic Regulation by Increasing Global Methylation and Gene Expression of MLH1 and DNMT1 Dose Dependently in Caco‐2 Cells
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  95. Requirement of the transcription factor YB-1 for maintaining the stemness of cancer stem cells and reverting differentiated cancer cells into cancer stem cells
    Fan Yang, Pei Cui, Lu Yu, Xiaobo Zhang · 2019 · Stem Cell Research & Therapy
  96. The Response of Living Organisms to Low Radiation Environment and Its Implications in Radiation Protection
    Mauro Belli, Luca Indovina · 2020 · Frontiers in Public Health
  97. Understanding the Mechanisms by Which Epigenetic Modifiers Avert Therapy Resistance in Cancer
    Quagliano, Anthony, Gopalakrishnapillai, Anilkumar, Barwe, Sonali P. · 2020 · Frontiers in Oncology
  98. Integration of High-Resolution Methylome and Transcriptome Analyses to Dissect Epigenomic Changes in Childhood Acute Lymphoblastic Leukemia
    Stephan Busche, Bing Ge, Ramon Oliveira Vidal, Jean-François Spinella, Virginie Saillour, Chantal Richer, Jasmine Healy, Shu‐Huang Chen, Arnaud Droit, Daniel Sinnett et al. · 2013 · Cancer Research
  99. Management of myelodysplastic syndromes after failure of response to hypomethylating agents
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  100. Chaetocin induces endoplasmic reticulum stress response and leads to death receptor 5-dependent apoptosis in human non-small cell lung cancer cells
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