A decade of exploring the cancer epigenome—biological and translational implications
DOI 10.1038/nrc3130
Cited by (1,001)
Items 601–700 of 1,001
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- Progress in epigenetic histone modification analysis by mass spectrometry for clinical investigationsÖzlem Önder, Simone Sidoli, Martin P Carroll, Benjamin Aaron Garcia · 2015 · Expert Review of Proteomics
- Epigenetic mechanisms and therapeutic targets of chemotherapy resistance in epithelial ovarian cancerJane Borley, Robert Eldon Brown · 2015 · Annals of Medicine
- Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancerYuting Chen, Charles E. Breeze, Shao Zhen, Stephan Beck, Andrew Erich Teschendorff · 2016 · Epigenetics & Chromatin
- Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer CellsMatteo Forloni, Romi Gupta, Arvindhan Govindasamy Nagarajan, Lisha Sun, Yuying Dong, Valentina Pirazzoli, Maria I Toki, Anna Wurtz, Mary Ann Melnick, Susumu S. Kobayashi et al. · 2016 · Cell Reports
- Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseasesRenate M. Hoogeveen, Matthias Nahrendorf, Niels Peter Riksen, Mihai Gheorghe Netea, Menno P.J. de Winther, Esther Lutgens, Børge Grønne Nordestgaard, Michel Neidhart, Erik S.G. Stroes, Alberico Luigi Catapano et al. · 2017 · European Heart Journal
- Integrative Epigenetic Analysis Reveals Therapeutic Targets to the DNA Methyltransferase Inhibitor Guadecitabine (SGI‐110) in Hepatocellular CarcinomaMinmin Liu, Lian Zhang, Hongtao Li, Toshinori Hinoue, Wanding Zhou, Hitoshi Ohtani, Anthony B. El-Khoueiry, John R. Daniels, Casey Lee O'Connell, Tanya Barauskas Dorff et al. · 2018 · Hepatology
- Histone Methyltransferase SETDB1 Promotes the Progression of Colorectal Cancer by Inhibiting the Expression of TP53Ke-Li Chen, Fengjiao Zhang, Jie Ding, Yonghao Liang, Zetao Zhan, Yizhi Zhan, Longhua Chen, Yi� Ding · 2017 · Journal of Cancer
- Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasivenessGi-Cheon Kim, Ho‐Keun Kwon, Choong‐Gu Lee, Ravi Prakash Verma, Dipayan Rudra, Taemook Kim, Keunsoo Kang, Jong Hee Nam, Young Kim, Sin‐Hyeog Im · 2018 · Oncogenesis
- Transcriptional Selectivity of Epigenetic Therapy in CancerTakahiro Sato, Matteo Cesaroni, Woonbok Chung, Shoghag B. Panjarian, Anthony Tran, Jozef Madžo, Yasuyuki Okamoto, Hanghang Zhang, Xiaowei Chen, Jaroslav Jelı́nek et al. · 2016 · Cancer Research
- Genome-wide DNA methylation profile identified a unique set of differentially methylated immune genes in oral squamous cell carcinoma patients in IndiaBaidehi Basu, Joyeeta Chakraborty, Aditi Chandra, Atul Katarkar, Jadav Baldevbhai, Debjit Dhar Chowdhury, Jay Gopal Ray, Keya Chaudhuri, Raghunath Chatterjee · 2017 · Clinical Epigenetics
- Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell CarcinomaAli Mehdi, Yasser Riazalhosseini · 2017 · International Journal of Molecular Sciences
- ZNF677 Suppresses Akt Phosphorylation and Tumorigenesis in Thyroid CancerYujun Li, Qi Yang, Haixia Guan, Bingyin Shi, Meiju Ji, Peng Hou · 2018 · Cancer Research
- Differential Methylation and Acetylation as the Epigenetic Basis of Resveratrol’s Anticancer ActivityMohd Farhan, Mohammad Fahad Ullah, Mohd Faisal, Ammad Ahmad Farooqı, Uteuliyev Yerzhan Sabitaliyevich, Bernhard Biersack, Aamir Ahmad · 2019 · Medicines
- Small Molecule Control of Chromatin RemodelingAidan Finley, Robert A. Copeland · 2014 · Chemistry & Biology
- Evodiamine-inspired dual inhibitors of histone deacetylase 1 (HDAC1) and topoisomerase 2 (TOP2) with potent antitumor activityYahui Huang, Shuqiang Chen, Shanchao Wu, Guoqiang Dong, Chunquan Sheng · 2019 · Acta Pharmaceutica Sinica B
- Zebularine elevates STING expression and enhances cGAMP cancer immunotherapy in miceJunzhong Lai, Yajuan Fu, Shuoran Tian, Shanlu Huang, Xuan Luo, Lili Lin, Xing Zhang, Hanze Wang, Zhang Lin, Heng Zhao et al. · 2021 · Molecular Therapy
- Epigenetics and environment in breast cancer: New paradigms for anti-cancer therapiesChitra Thakur, Yiran Qiu, Yao Shi Fu, Zhuoyue Bi, Wenxuan Zhang, Haoyan Ji, Fei Chen · 2022 · Frontiers in Oncology
- DNA Methylation Profiles at Precancerous Stages Associated with Recurrence of Lung AdenocarcinomaTakashi Sato, Eri Arai, Takashi Kohno, Koji Tsuta, Shun-ichi Watanabe, Kenzo Soejima, Tomoko Betsuyaku, Yae Kanai · 2013 · PLoS ONE
- Quantification of 5-methylcytosine, 5-hydroxymethylcytosine and 5-carboxylcytosine from the blood of cancer patients by an enzyme-based immunoassayBasudev Chowdhury, Il‐Hoon Cho, Noah M. Hahn, Joseph Irudayaraj · 2014 · Analytica Chimica Acta
- A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survivalShahzia Anjum, Evangelia-O Fourkala, Michal Zikán, Andrew Wong, Aleksandra Gentry‐Maharaj, Allison Jones, Rebecca Hardy, David Cibula, Diana J. Kuh, Ian J. Jacobs et al. · 2014 · Genome Medicine
- A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2′-DeoxycytidineBenjamin R. Leadem, Ioannis Kagiampakis, CATHERINE A. WILSON, Tommy K. Cheung, David P. Arnott, Patrick Trojer, Marie Classon, Hariharan Easwaran, Stephen B. Baylin · 2017 · Cancer Research
- The role of epigenetic therapies in colorectal cancerMarina Baretti, Nilofer Saba Azad · 2018 · Current Problems in Cancer
- The Crosstalk Between Epigenetic Mechanisms and Alternative RNA Processing RegulationJian Zhang, Yizhe Zhang, Jing Jiang, Cheng‐Guo Duan · 2020 · Frontiers in Genetics
- TET-Mediated Epigenetic Regulation in Immune Cell Development and DiseaseNikolas J. Tsiouplis, David Wesley Bailey, Lilly F. Chiou, Fiona Jane Wissink, Ageliki Tsagaratou · 2021 · Frontiers in Cell and Developmental Biology
- Cell-free DNA methylation markers for differential diagnosis of hepatocellular carcinomaBiyuan Luo, Fang Ma, Hao Liu, Jixiong Hu, Le Rao, Chunying Liu, Yongfang Jiang, Shuyu Kuang-Zeng, Xuan Lin, Chenyang Wang et al. · 2022 · BMC Medicine
- Methylated DNA Immunoprecipitation and High-Throughput Sequencing (MeDIP-seq) Using Low Amounts of Genomic DNAMingtao Zhao, Jeffrey J. Whyte, Garrett M. Hopkins, Mark D. Kirk, Randall S. Prather · 2014 · Cellular Reprogramming
- Functional proteomics of the epigenetic regulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics for translational medicineMasaru Katoh · 2015 · Expert Review of Proteomics
- Mathematical model of adult stem cell regeneration with cross-talk between genetic and epigenetic regulationJinzhi Lei, Simon A. Levin, Qing Hua Nie · 2014 · Proceedings of the National Academy of Sciences
- Anticancer Natural Compounds as Epigenetic Modulators of Gene ExpressionEdward A. Ratovitski · 2017 · Current Genomics
- A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from the TACL consortiumWeili Sun, Timothy Junius Triche, Jemily Malvar, Paul S. Gaynon, Richard Sposto, Xiaojing Yang, Henrique Neves da Silva Bittencourt, Andrew E. Place, Yoav H. Messinger, Chris Fraser et al. · 2018 · Blood
- Rewiring of cisplatin-resistant bladder cancer cells through epigenetic regulation of genes involved in amino acid metabolismAustin Yeon, Sungyong You, Minhyung Kim, Amit Gupta, Myung Hee Park, Daniel J. Weisenberger, Gangning Liang, Jayoung Kim · 2018 · Theranostics
- Epigenetic Reprogramming of TGF-β Signaling in Breast CancerSudha Suriyamurthy, David A. Baker, Peter ten Dijke, Prasanna Vasudevan Iyengar · 2019 · Cancers
- Chemotherapy-Induced Distal Enhancers Drive Transcriptional Programs to Maintain the Chemoresistant State in Ovarian CancerStephen Shang, Jiekun Yang, Amir Anthony Jazaeri, Alexander James Duval, Turan Tufan, Natasha Lopes Fischer, Mouadh Benamar, Fadila Guessous, In-Young Lee, Robert M. Campbell et al. · 2019 · Cancer Research
- Deciphering DNA methylation signatures of pancreatic cancer and pancreatitisFrancesco Natale, Maria Vivo, Geppino Falco, Tiziana Angrisano · 2019 · Clinical Epigenetics
- Aberrant DNA hypermethylation of SDHC: a novel mechanism of tumor development in Carney triadFlorian Haller, Evgeny A. Moskalev, Fabio Rueda Faucz, Sarah Barthelmesz, Stefan Wiemann, Matthias Bieg, Guillaume Assié, Jerome Yves Bertherat, Inga‐Marie Schaefer, Claudia Otto et al. · 2015 · Endocrine Abstracts
- Zinc Finger Readers of Methylated DNANicholas O. Hudson, Bethany A. Buck‐Koehntop · 2018 · Molecules
- Per- and Polyfluoroalkyl Substances, Epigenetic Age and DNA Methylation: A Cross-Sectional Study of FirefightersJaclyn M. Goodrich, Miriam M. Calkins, Alberto Juan Caban-Martinez, Todd A. Stueckle, Casey C. Grant, Antonia M. Calafat, Amy Nematollahi, Alesia M. Jung, Judith M. Graber, Timothy G. Jenkins et al. · 2021 · Epigenomics
- Multiplex Digital Methylation‐Specific PCR for Noninvasive Screening of Lung CancerYang Zhao, Christine M. O’Keefe, Kuangwen Hsieh, Leslie Cope, Sonali C. Joyce, Thomas R. Pisanic, James Gordon Herman, Tza‐Huei Wang · 2023 · Advanced Science
- lnflammation-induced epigenetic switches in cancerMatjaž Rokavec, Meryem Gülfem Öner, Heiko Hermeking · 2015 · Cellular and Molecular Life Sciences
- Epigenetics: The neglected key to minimize learning and memory deficits in Down syndromeAlain D. Dekker, Peter Paul De Deyn, Marianne G. Rots · 2014 · Neuroscience & Biobehavioral Reviews
- Discovery of an orally active subtype-selective HDAC inhibitor, chidamide, as an epigenetic modulator for cancer treatmentDesi Pan, Qian‐Jiao Yang, Xin Fu, Song Shan, Jing-Zhong Zhu, Kun Zhang, Zhibin Li, Zhiqiang Ning, Xianping Lu · 2014 · MedChemComm
- F2RL3 methylation, lung cancer incidence and mortalityYan Zhang, Ben Schöttker, José Manuel Ordóñez-Mena, Bernd Holleczek, Rongxi Yang, Barbara Burwinkel, Katja Butterbach, Hermann Brenner · 2015 · International Journal of Cancer
- The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins?Andrea Scelfo, Andrea Piunti, Diego Pasini · 2014 · FEBS Journal
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- Alterations of DNA methylome in human bladder cancerAhmad Besarati Nia, Myles Cockburn, Stella Tommasi · 2013 · Epigenetics
- Analysis of Helios gene expression and Foxp3 TSDR methylation in the newly diagnosed Rheumatoid Arthritis patientsParisa Zafari, Kheirollah Yari, Shayan Mostafaei, Nasrin Iranshahi, Shirin Assar, Adel Fekri, Mahdi Taghadosi · 2018 · Immunological Investigations
- Regulating Methylation at H3K27: A Trick or Treat for Cancer Cell PlasticityProvas Das, Joseph H. Taube · 2020 · Cancers
- The recently suggested intestinal cancer stem cell markerDCLK1is an epigenetic biomarker for colorectal cancerHege Marie Vedeld, Rolf Inge Skotheim, Ragnhild A. Lothe, Guro Elisabeth Lind · 2014 · Epigenetics
- Acute Hypersensitivity of Pluripotent Testicular Cancer-Derived Embryonal Carcinoma to Low-Dose 5-Aza Deoxycytidine Is Associated with Global DNA Damage-Associated p53 Activation, Anti-Pluripotency and DNA DemethylationBijesh Kumar Biswal, Maroun J. Beyrouthy, Mary P. Hever-Jardine, David Armstrong, Craig R. Tomlinson, Brock C. Christensen, Carmen J. Marsit, Michael J. Spinella · 2012 · PLoS ONE
- SEPT9 and SHOX2 DNA methylation status and its utility in the diagnosis of colonic adenomas and colorectal adenocarcinomasAlexander Semaan, Anne van Ellen, Sebastian Meller, Dominik Bergheim, Vittorio Branchi, Philipp Lingohr, Diane Goltz, Jörg C. Kalff, Glen Kristiansen, Hanno Matthaei et al. · 2016 · Clinical Epigenetics
- Genistein Prevents BRCA1 CpG Methylation and Proliferation in Human Breast Cancer Cells with Activated Aromatic Hydrocarbon ReceptorDonato F. Romagnolo, Micah G. Donovan, Andreas J. Papoutsis, Tom C. Doetschman, Ornella I. Selmin · 2017 · Current Developments in Nutrition
- Methylation-mediated gene silencing as biomarkers of gastric cancer: A reviewJun Nakamura · 2014 · World Journal of Gastroenterology
- Reconciling Non-Genetic Plasticity with Somatic Evolution in CancerSui Huang · 2021 · Trends in cancer
- CBX7 suppresses urinary bladder cancer progression via modulating AKR1B10–ERK signalingZhengnan Huang, Yi‐Lin Yan, Zhen Yuan Zhu, Jiakuan Liu, Xiao Hong He, Sumiya Dalangood, Meiqian Li, Mingyue Tan, Jinming Cai, Pengfei Tang et al. · 2021 · Cell Death and Disease
- Epigenetic Dysregulations in Merkel Cell Polyomavirus-Driven Merkel Cell CarcinomaJohn Charles Rotondo, Chiara Mazziotta, Carmen Lanzillotti, Mauro G. Tognon, Fernanda Martini · 2021 · International Journal of Molecular Sciences
- Targeting epigenetic modulators using PROTAC degraders: Current status and future perspectiveThomas Webb, Conner Craigon, Alessio Ciulli · 2022 · Bioorganic & Medicinal Chemistry Letters
- Evaluation of INK4A promoter methylation using pyrosequencing and circulating cell-free DNA from patients with hepatocellular carcinomaGengming Huang, Joseph D. Krocker, Jason L. Kirk, Shehzad Nawaz Merwat, Hyunsu Ju, Roger D. Soloway, Lucas R. Wieck, Albert Li, Anthony O. Okorodudu, John R. Petersen et al. · 2014 · Clinical Chemistry and Laboratory Medicine (CCLM)
- Epigenetic determinants of ovarian clear cell carcinoma biologyKen D Yamaguchi, Zhiqing Huang, Noriomi Matsumura, Masaki Mandai, Takako Okamoto, Tsukasa Baba, Ikuo Konishi, Andrew Berchuck, Susan K. Murphy · 2013 · International Journal of Cancer
- Improving cancer immunotherapy with DNA methyltransferase inhibitorsMohammad H. Saleh, Lei Wang, Michael S. Goldberg · 2015 · Cancer Immunology Immunotherapy
- Gender Differences in Adipocyte Metabolism and Liver Cancer ProgressionOtto Ka-Wing Cheung, Alfred S.L. Cheng · 2016 · Frontiers in Genetics
- Enzymology of Mammalian DNA MethyltransferasesRenata Zofia Jurkowska, Albert Jeltsch · 2016 · Advances in experimental medicine and biology
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- A phase I, pharmacokinetic, and pharmacodynamic evaluation of the DNA methyltransferase inhibitor 5-fluoro-2′-deoxycytidine, administered with tetrahydrouridineEdward M. Newman, Robert J. Morgan, Shivaani Kummar, Jan Hendrik Beumer, M. Suzette Blanchard, Christopher Ruel, Anthony B. El-Khoueiry, Mary I. Carroll, Jessie Hou, Chun Li et al. · 2015 · Cancer Chemotherapy and Pharmacology
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- The Application of Genome-Wide 5-Hydroxymethylcytosine Studies in Cancer ResearchJohn P. Thomson, Richard R. Meehan · 2016 · Epigenomics
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- Order Matters: The Order of Somatic Mutations Influences Cancer EvolutionDavid G. Kent, Anthony R. Green · 2017 · Cold Spring Harbor Perspectives in Medicine
- INHBB Is a Novel Prognostic Biomarker Associated with Cancer‐Promoting Pathways in Colorectal CancerJinpeng Yuan, Aosi Xie, Qiangjian Cao, Xinxin Li, Juntian Chen · 2020 · BioMed Research International
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- Epigenetic silencing of miR-708 enhances NF-κB signaling in chronic lymphocytic leukemiaConstance Regina Baer, Christopher C. Oakes, Amy S. Ruppert, Rainer Claus, Soo-Zin Kim-Wanner, Daniel Mertens, Thorsten Zenz, Stephan Stilgenbauer, John C. Byrd, Christoph Plass · 2015 · International Journal of Cancer
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- S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cellsYan Wang, Zhong Sheng Sun, Moshe Szyf A · 2017 · Oncotarget
- Counteraction of Oxidative Stress by Vitamin E Affects Epigenetic Regulation by Increasing Global Methylation and Gene Expression of MLH1 and DNMT1 Dose Dependently in Caco‐2 CellsKatja Zappe, Angelika Pointner, Olivier J. Switzeny, Ulrich Magnet, Elena Tomeva, Jutta Heller, George Mare, Karl‐Heinz Wagner, Siegfried Knasmüller, Alexander G. Haslberger · 2018 · Oxidative Medicine and Cellular Longevity
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- Understanding the Mechanisms by Which Epigenetic Modifiers Avert Therapy Resistance in CancerQuagliano, Anthony, Gopalakrishnapillai, Anilkumar, Barwe, Sonali P. · 2020 · Frontiers in Oncology
- Integration of High-Resolution Methylome and Transcriptome Analyses to Dissect Epigenomic Changes in Childhood Acute Lymphoblastic LeukemiaStephan Busche, Bing Ge, Ramon Oliveira Vidal, Jean-François Spinella, Virginie Saillour, Chantal Richer, Jasmine Healy, Shu‐Huang Chen, Arnaud Droit, Daniel Sinnett et al. · 2013 · Cancer Research
- Management of myelodysplastic syndromes after failure of response to hypomethylating agentsÁngela Gil Pérez, Guillermo Montalban Bravo · 2019 · Therapeutic Advances in Hematology
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