A decade of exploring the cancer epigenome—biological and translational implications

Baylin, Stephen B., Jones, Peter A.·2011·Nature Reviews Cancer

DOI 10.1038/nrc3130

Cited by (1,001)

Items 101–200 of 1,001

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Bing Hu, Einar Castillo, Louise Harewood, Paola Ostano, Alexandre Reymond, Reinhard Dummer, Wassim Raffoul, Wolfram Hoetzenecker, Günther F.L. Hofbauer, Gian Paolo Dotto · 2012 · Cell
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Naixin Liang, Bingsi Li, Ziqi Jia, Chenyang Wang, Pancheng Wu, Tao Zheng, Yanyu Wang, Fujun Qiu, Yijun Wu, Jing Su et al. · 2021 · Nature Biomedical Engineering
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Paulina Anna Miziak, Marzena Teresa Baran, Ewa Błaszczak, Alicja Przybyszewska-Podstawka, Joanna Kałafut, Jolanta Smok-Kalwat, Magdalena Dmoszyńska‐Graniczka, Michał Kiełbus, Andrzej Stepulak · 2023 · Cancers
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Lochhead, Paul, Chan, Andrew T, Nishihara, Reiko, Fuchs, Charles S, Beck, Andrew H, Giovannucci, Edward, Ogino, Shuji · 2015 · Modern Pathology
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Albert Jeltsch, Renata Zofia Jurkowska · 2016 · Nucleic Acids Research
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Jorge Landgrave-Gómez, Octavio Fabián Mercado-Gómez, Rosalinda Guevara‐Guzmán · 2015 · Frontiers in Cellular Neuroscience
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Tongxin Ge, Xiang Gu, Renbing Jia, Shengfang Ge, Peiwei Chai, Ai Zhuang, Xianqun Fan · 2022 · 癌症：英文版
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Ben P. Williams, Daniela Pignatta, Steven Henikoff, Mary A. Gehring · 2015 · PLoS Genetics
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Nidal E. Muvarak, Khadiza Chowdhury, Limin Xia, Carine Robert, Eun Yong Choi, Yi Cai, Marina A. Bellani, Ying S. Zou, Zeba N. Singh, Vu H. Duong et al. · 2016 · Cancer Cell
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Jinfeng Liu, William Lee, Zhaoshi Jiang, Zhong‐Qiang Chen, Suchit Jhunjhunwala, Peter M. Haverty, Florian Gnad, Yinghui Guan, Houston Gilbert, Jeremy Stinson et al. · 2012 · Genome Research
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R. Beekman, V. Chapaprieta, N. Russiñol, Roser Vilarrasa-Blasi, Núria Verdaguer-Dot, J. Martens, M. Duran-Ferrer, M. Kulis, François Serra, Biola M. Javierre et al. · 2018 · Nature Medicine
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Jennifer Ma, Jeremy S. Setton, Nancy Y. Lee, Nadeem Riaz, Simon N. Powell · 2018 · Nature Communications
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Feng Liu, Gary C. Hon, Genaro R. Villa, Kristen M. Turner, Shiro Ikegami, Huijun Yang, Zhen Ye, Bin Li, Samantha Kuan, Ah Young Lee et al. · 2015 · Molecular Cell
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Chen Gu, Thomas J. Begley, Peter C. Dedon · 2014 · FEBS Letters
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Michelle J. Vaz, Stephen Y. Hwang, Ioannis Kagiampakis, Jillian A. Phallen, Ashwini Patil, Heather M. O’Hagan, Lauren M. Murphy, Cynthia A. Zahnow, Edward Gabrielson, Victor E. Velculescu et al. · 2017 · Cancer Cell
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Shah, Nakul M., Jang, H. Josh, Liang, Yonghao, Maeng, Ju Heon, Tzeng, Shin-Cheng, Wu, Angela, Basri, Noah L., Qu, Xuan, Fan, Changxu, Li, Amy et al. · 2023 · Nature Genetics
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