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Role of ABL family kinases in cancer: from leukaemia to solid tumours
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Dasatinib, the compound used to inhibit SRC in most of the authors' assays, is a notoriously promiscuous compound with many potential targets.
“dasatinib, the compound used to inhibit SRC in most of our assays, is a notoriously promiscuous compound with many potential targets (Greuber et al., 2013).”
From A Landscape of Therapeutic Cooperativity in KRAS Mutant Cancers Reveals Principles for Controlling Tumor Evolution (2017) · cites this paper as Greuber et al., 2013
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Cerami, E., Gao, J., Dogrusoz, U., Gross, B. E., Sumer, S. O., Aksoy, B. A., Jacobsen, A., Byrne, C. J., Heuer, M. L., Larsson, E., et al. (2012) · Cancer Discovery · doi:10.1158/2159-8290.cd-12-0095 · Cited by 17,455
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Quyn, A. J., Appleton, P. L., Carey, F. A., Steele, R. J. C., Barker, N., Clevers, H., Ridgway, R. A., Sansom, O. J., & Näthke, I. S. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2009.12.007 · Cited by 242
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Metadata
- Authors
- Greuber, E. K., Smith-Pearson, P., Wang, J., & Pendergast, A. M.
- Venue
- Nature Reviews Cancer
- Published
- 2013-07-11
- Volume
- 13
- Issue
- 8
- Pages
- 559-571
- ISSN
- 1474-175X
- 1474-1768
- PMC
- PMC3935732
- Cited by
- 432
- References
- 10
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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