Trophic macrophages in development and disease

Inflammation and cancer

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Obesity is associated with macrophage accumulation in adipose tissue

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Exploring the full spectrum of macrophage activation

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

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Immunobiology of Dendritic Cells

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Alternative activation of macrophages

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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

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Role of angiogenesis in tumor growth and metastasis

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Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

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The role of tumour‐associated macrophages in tumour progression: implications for new anticancer therapies

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Smoldering and polarized inflammation in the initiation and promotion of malignant disease

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The role of myeloid cells in the promotion of tumour angiogenesis

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Colony-Stimulating Factor 1 Promotes Progression of Mammary Tumors to Malignancy

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RANK is essential for osteoclast and lymph node development.

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Colony-stimulating factors in inflammation and autoimmunity

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A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors

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Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects

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The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cells.

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VEGF-Induced Adult Neovascularization: Recruitment, Retention, and Role of Accessory Cells

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The origin and function of tumor-associated macrophages

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Macrophages Regulate the Angiogenic Switch in a Mouse Model of Breast Cancer

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Direct Visualization of Macrophage-Assisted Tumor Cell Intravasation in Mammary Tumors

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Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse.

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Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain

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Role of tumor-associated macrophages in tumor progression and invasion

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Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology.

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Involvement of Granulocyte-Macrophage Colony-Stimulating Factor in Pulmonary Homeostasis

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Selective Ablation of Proliferating Microglial Cells Exacerbates Ischemic Injury in the Brain

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Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells

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Discovery of a Cytokine and Its Receptor by Functional Screening of the Extracellular Proteome

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Ablation of CD11c-Positive Cells Normalizes Insulin Sensitivity in Obese Insulin Resistant Animals

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“Re-educating” tumor-associated macrophages by targeting NF-κB

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Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats

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Macrophage diversity in renal injury and repair

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A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF- B and enhanced IRF-3/STAT1 activation)

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A macrophage colony-stimulating factor receptor–green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse

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The mononuclear phagocyte system

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Colony-stimulating factor-1 in immunity and inflammation

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Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse

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Osteopetrosis in mice lacking haematopoietic transcription factor PU.1

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Macrophages as APC and the Dendritic Cell Myth

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Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis

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Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis

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Tumor-Associated Macrophages Press the Angiogenic Switch in Breast Cancer

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Postnatal mammary gland development requires macrophages and eosinophils

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Satellite cells attract monocytes and use macrophages as a support to escape apoptosis and enhance muscle growth

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Macrophages Induce Invasiveness of Epithelial Cancer Cells Via NF-κB and JNK

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WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

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Metchnikoff and the phagocytosis theory

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Requirement of DNase II for Definitive Erythropoiesis in the Mouse Fetal Liver

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Macrophage contributions to ovarian function

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Uterine DCs are crucial for decidua formation during embryo implantation in mice

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Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines

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A potential role of macrophage activation in the treatment of cancer

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Tumor-Associated Macrophages in Breast Cancer

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Three pathways to mature macrophages in the early mouse yolk sac

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Targeting Tumor-Associated Macrophages and Inhibition of MCP-1 Reduce Angiogenesis and Tumor Growth in a Human Melanoma Xenograft

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The Macrophage Growth Factor CSF-1 in Mammary Gland Development and Tumor Progression

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Tie2-expressing monocytes: regulation of tumor angiogenesis and therapeutic implications

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Colony-Stimulating Factor-1 Blockade by Antisense Oligonucleotides and Small Interfering RNAs Suppresses Growth of Human Mammary Tumor Xenografts in Mice

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Activated macrophages promote Wnt signalling through tumour necrosis factor‐α in gastric tumour cells

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Macrophages promote collagen fibrillogenesis around terminal end buds of the developing mammary gland

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Microglia: phagocyte and glia cell

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Regulation of macrophage function in tumors: the multifaceted role of NF-κB

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Involvement of leukocytes and cytokines in the ovulatory process and corpus luteum function

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Colony-Stimulating Factor-1 Antibody Reverses Chemoresistance in Human MCF-7 Breast Cancer Xenografts

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Macrophage infiltration into adipose tissue may promote angiogenesis for adipose tissue remodeling in obesity

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Anti-Colony-Stimulating Factor-1 Antibody Staining in Primary Breast Adenocarcinomas Correlates With Marked Inflammatory Cell Infiltrates and Prognosis

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High-Density Gene Expression Analysis of Tumor-Associated Macrophages from Mouse Mammary Tumors

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Requirement of macrophages and eosinophils and their cytokines/chemokines for mammary gland development

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Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r–EGFP transgene reporter

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The colony-stimulating factors and collagen-induced arthritis: exacerbation of disease by M-CSF and G-CSF and requirement for endogenous M-CSF

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CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain

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Myeloid Development Is Selectively Disrupted in PU.1 Null Mice

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Myeloid lineage progenitors give rise to vascular endothelium

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Arteriogenesis depends on circulating monocytes and macrophage accumulation and is severely depressed in op/op mice

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Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1

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Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages

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