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Cited by 2,112

The DOI matches its Crossref record; 182 of the 182 references it cites were found in a registry or an index.

MicroRNA biogenesis pathways in cancer

Open access
Lin, Shuibin, Gregory, Richard I.·2015·Nature Reviews Cancer

Abstract

MicroRNAs (miRNAs) are critical regulators of gene expression. Amplification and overexpression of individual 'oncomiRs' or genetic loss of tumour suppressor miRNAs are associated with human cancer and are sufficient to drive tumorigenesis in mouse models. Furthermore, global miRNA depletion caused by genetic and epigenetic alterations in components of the miRNA biogenesis machinery is oncogenic. This, together with the recent identification of novel miRNA regulatory factors and pathways, highlights the importance of miRNA dysregulation in cancer.

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Crossref · 10.1038/nrc3932

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Metadata

Authors
Lin, S., & Gregory, R. I.
Venue
Nature Reviews Cancer
Published
2015-05-22
Volume
15
Issue
6
Pages
321-333
ISSN
  • 1474-175X (ISSN-L)
  • 1474-1768
OpenAlex
W2105549148
Cited by
2,112
References
182
FWCI
18.44
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: MicroRNA biogenesis pathways in cancer. https://app.cochat.ai/papers/10.1038/nrc3932
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Lin, S., & Gregory, R. I. (2015). MicroRNA biogenesis pathways in cancer. Nature Reviews Cancer. https://doi.org/10.1038/nrc3932

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.