The Ever-Expanding Myokinome: Discovery Challenges and Therapeutic Implications

Cited by (279)

Items 101–200 of 279

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2. Relationship between diet/exercise and pharmacotherapy to enhance the GLP‐1 levels in type 2 diabetes
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3. Acute administration of IL-6 improves indices of hepatic glucose and insulin homeostasis in lean and obese mice
   Willem T. Peppler, Logan K. Townsend, Grace Margaret-Eleanor Meers, Matthew R. Panasevich, Rebecca E. K. MacPherson, R. Scott Rector, David Charles Wright · 2018 · American Journal of Physiology-Gastrointestinal and Liver Physiology
4. Mitochondrial respiration variability and simulations in human skeletal muscle: The Gene SMART study
   Macsue Jacques, Jujiao Kuang, David John Bishop, Xu Yan, Javier Alvarez‐Romero, Fiona Munson, ANDREW P. GARNHAM, Ioannis D. Papadimitriou, Sarah Amandine Caroline Voisin, Nir Eynon · 2020 · The FASEB Journal
5. Irisin ameliorates diabetic kidney disease by restoring autophagy in podocytes
   Weiyan Lai, Dan Luo, Yin Li, Yuanqing Li, Qianqian Wang, Zhaoyong Hu, Zengchun Ye, Hui Peng · 2023 · The FASEB Journal
6. Mitochondrial Stress and Mitokines: Therapeutic Perspectives for the Treatment of Metabolic Diseases
   Benyuan Zhang, Joon Young Chang, Min Hee Lee, Sang Hyeon Ju, Hyon‐Seung Yi, Minho Shong · 2024 · Diabetes & Metabolism Journal
7. Three-dimensional contractile muscle tissue consisting of human skeletal myocyte cell line
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8. Skeletal Muscle Nrf2 Contributes to Exercise-Evoked Systemic Antioxidant Defense Via Extracellular Vesicular Communication
   Lie Gao, Hanjun Wang, Changhai Tian, Irving H. Zucker · 2021 · Exercise and Sport Sciences Reviews
9. Chronic exercise mitigates disease mechanisms and improves muscle function in myotonic dystrophy type 1 mice
   Alexander Manta, Derek William Stouth, Donald Xhuti, Leon Chi, Irena A. Rebalka, Jayne M. Kalmar, Thomas James Hawke, Vladimir Ljubicic · 2019 · The Journal of Physiology
10. An expanded repertoire of intensity-dependent exercise-responsive plasma proteins tied to loci of human disease risk
    James Sawalla Guseh, Timothy W. Churchill, Ashish Yeri, Claire T. Lo, Marcel G. Brown, Nicholas E. Houstis, Krishna G. Aragam, Daniel E. Lieberman, Anthony Rosenzweig, Aaron Leigh Baggish · 2020 · Scientific Reports
11. New Horizon: Exercise and a Focus on Tissue-Brain Cross Talk.
    Logan K. Townsend, R. MacPherson, D. Wright · 2021 · Journal of Clinical Endocrinology and Metabolism
12. Physical Exercise Restrains Cancer Progression through Muscle-Derived Factors
    Argyro Papadopetraki, M. Maridaki, F. Zagouri, M. Dimopoulos, M. Koutsilieris, A. Philippou · 2022 · Cancers
13. Physical activity and advanced cancer: evidence of exercise‐sensitive genes regulating prostate cancer cell proliferation and apoptosis
    Raphaela Schwappacher, Kristin Schink, Svetlana Sologub, Walburga Dieterich, Dejan Reljic, Oliver Friedrich, Hans Joachim Herrmann, Markus Friedrich Neurath, Yurdagül Zopf · 2020 · The Journal of Physiology
14. Resistance Training Diminishes the Expression of Exosome CD63 Protein without Modification of Plasma miR-146a-5p and cfDNA in the Elderly
    Brisamar Estébanez, Nishant P. Visavadiya, José António de Paz Fernández, MICHAEL A. WHITEHURST, Maria Jose Cuevas, Javier González‐Gallego, Chun‐Jung Huang · 2021 · Nutrients
15. Control of muscle satellite cell function by specific exercise‐induced cytokines and their applications in muscle maintenance
    Qian Guo, Qing Luo, Guanbin Song · 2024 · Journal of Cachexia Sarcopenia and Muscle
16. Exercise Training in Cancer Control and Treatment
    Jesper Frank Christensen, Casper Simonsen, Pernille Højman · 2019 · Comprehensive physiology
17. Dissociation of Bone Resorption and Formation in Spaceflight and Simulated Microgravity: Potential Role of Myokines and Osteokines?
    Patrick Lau, Laurence Vico, Jörn Rittweger · 2022 · Biomedicines
18. Sex-Specific Ventricular and Vascular Adaptations to Exercise
    Jill Nicole Barnes, Qi Fu · 2018 · Advances in experimental medicine and biology
19. Short‐term aerobic conditioning prior to resistance training augments muscle hypertrophy and satellite cell content in healthy young men and women
    Aaron C. Q. Thomas, Alex Brown, Aidan A. Hatt, Katherine Manta, Anamaria Costa‐Parke, Michael J. Kamal, Sophie Joanisse, Chris McGlory, Stuart M. Phillips, Dinesh Arun Kumbhare et al. · 2022 · The FASEB Journal
20. Revisiting skeletal myopathy and exercise training in heart failure: Emerging role of myokines
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21. Impact of Physical Activity on Cellular Metabolism Across Both Neurodegenerative and General Neurological Conditions: A Narrative Review
    Vicente Javier Clemente‐Suárez, Alejandro Rubio-Zarapuz, Pedro Belinchón-deMiguel, Ana Isabel Beltrán-Velasco, Alexandra Martín-Rodríguez, José Francisco Tornero-Aguilera · 2024 · Cells
22. Examination of the Myokine Response in Pregnant and Non-pregnant Women Following an Acute Bout of Moderate-Intensity Walking
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23. Meteorin-like protein overexpression ameliorates fulminant hepatitis in mice by inhibiting chemokine-dependent immune cell infiltration
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24. Effect of Forced Physical Activity on the Severity of Experimental Colitis in Normal Weight and Obese Mice. Involvement of Oxidative Stress and Proinflammatory Biomarkers
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25. Inhibition of ubiquitin‐specific protease 2 causes accumulation of reactive oxygen species, mitochondria dysfunction, and intracellular ATP decrement in C2C12 myoblasts
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26. Crosstalk between Bone and Muscles during Physical Activity
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27. Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition
    Serge Ducommun, Paulo R. Jannig, Igor Červenka, Marta Murgia, Melanie J. Mittenbühler, Ekaterina Chernogubova, José Maria Moreira Dias, Baptiste Jude, Jorge C. Correia, Jonathan G. Van Vranken et al. · 2024 · Molecular Metabolism
28. Contribution of High-Intensity Interval Exercise in the Fasted State to Fat Browning: Potential Roles of Lactate and β-Hydroxybutyrate
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29. Effect of skeletal muscle phenotype and gender on fasting-induced myokine expression in mice
    Weihua Jia, Nuoqi Wang, Lin Yin, Xi Chen, Biyu Hou, Guifen Qiang, Chi Bun Chan, Xiuying Yang, Guanhua Du · 2019 · Biochemical and Biophysical Research Communications
30. A Tead1-Apelin axis directs paracrine communication from myogenic to endothelial cells in skeletal muscle
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31. Exercise and Metabolic Health: The Emerging Roles of Novel Exerkines
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32. Muscle as an Endocrine Organ
    Grit Elster Legaard, Bente Klarlund Pedersen · 2018 · Elsevier eBooks
33. Myokines as mediators of exercise-induced cognitive changes in older adults: protocol for a comprehensive living systematic review and meta-analysis
    Wouter A. J. Vints, Evrim Gökçe, Antoine Langeard, Юлія Павлова, Özge Selin Çevik, Mohammad Mosaferi Ziaaldini, Jasemin Todri, Orges Lena, Giorgos K. Sakkas, Suzanne Jak et al. · 2023 · Frontiers in Aging Neuroscience
34. Exercise-Induced Myokines as Emerging Therapeutic Agents In Colorectal Cancer Prevention and Treatment
    Priya Roy, Sanjib Chowdhury, Hemant K. Roy · 2018 · Future Oncology
35. Molecular mechanisms and potential interventions during aging-associated sarcopenia
    Xiaoqin Luo, Jin Wang, Qingqing Ju, Tianyu Li, Xiuli Bi · 2024 · Mechanisms of Ageing and Development
36. Muscle-brain communication in pain: The key role of myokines
    Yuanyuan Wang, Zifeng Wu, Di Wang, Chaoli Huang, Jiali Xu, Cunming Liu, Chun Yang · 2021 · Brain Research Bulletin
37. The impact of sarcopenia on survival and treatment tolerance in patients with head and neck cancer treated with chemoradiotherapy
    Rita Bentahila, Philippe Giraud, Pierre Decazes, S. Kreps, Paula Nay, Augustin Chatain, Emmanuelle Fabiano, Catherine Durdux · 2022 · Cancer Medicine
38. Cell fibers promote proliferation of co-cultured cells on a dish
    Ai Shima, Akane Itou, Shoji Takeuchi · 2020 · Scientific Reports
39. Impact of Intrinsic Muscle Weakness on Muscle–Bone Crosstalk in Osteogenesis Imperfecta
    Victoria L. Gremminger, Charlotte L. Phillips · 2021 · International Journal of Molecular Sciences
40. Marked Increased Production of Acute Phase Reactants by Skeletal Muscle during Cancer Cachexia
    Isabelle S. Massart, Geneviève Paulissen, Audrey Loumaye, Pascale Lause, Sarah A. Pötgens, Morgane M. Thibaut, Estelle Balan, Louise Deldicque, Azeddine Atfi, Edouard J. Louis et al. · 2020 · Cancers
41. Effects of fasting on the expression pattern of FGFs in different skeletal muscle fibre types and sexes in mice
    Weihua Jia, Nuoqi Wang, Lin Yin, Xi Chen, Biyu Hou, Jinhua Wang, Guifen Qiang, Chi Bun Chan, Xiuying Yang, Guanhua Du · 2020 · Biology of Sex Differences
42. Myokines: Novel therapeutic targets for diabetic nephropathy
    Ming Yang, Shilu Luo, Jinfei Yang, Wei Chen, Liyu He, Di Liu, Li Zhao, Xi Wang · 2022 · Frontiers in Endocrinology
43. Effects of exercise or metformin on myokine concentrations in patients with breast and colorectal cancer: A phase II multi‐centre factorial randomized trial
    Justin C. Brown, Guillaume Spielmann, Shengping Yang, Stephanie L. E. Compton, Lee W. Jones, Melinda L. Irwin, Jennifer A. Ligibel, Jeffrey A. Meyerhardt · 2024 · Journal of Cachexia Sarcopenia and Muscle
44. The Regulation of the Metastatic Cascade by Physical Activity: A Narrative Review
    Sophie van Doorslaer de ten Ryen, Louise Deldicque · 2020 · Cancers
45. Mechanisms, assessment, and exercise interventions for skeletal muscle dysfunction post-chemotherapy in breast cancer: from inflammation factors to clinical practice
    Pei Zhong, Xizhuang Li, Jiehua Li · 2025 · Frontiers in Oncology
46. Comparative Analysis of Skeletal Muscle Transcriptional Signatures Associated With Aerobic Exercise Capacity or Response to Training in Humans and Rats
    Yildiz Kelahmetoglu, Paulo R. Jannig, Igor Červenka, Lauren G. Koch, Steven L. Britton, Jiajia Zhou, Huating Wang, Matthew M. Robinson, K. Sreekumaran Nair, Jorge Lira Ruas · 2020 · Frontiers in Endocrinology
47. Preclinical techniques to investigate exercise training in vascular pathophysiology
    Gurneet S. Sangha, Craig J. Goergen, Steven J. Prior, Sushant M. Ranadive, Alisa Morss Clyne · 2021 · American Journal of Physiology-Heart and Circulatory Physiology
48. Sarcopenic obesity in liver disease: Handling both sides of the penny
    Yangyang Hui, Binxin Cui, Xiaoyu Wang, Mingyu Sun, Yifan Li, Wanting Yang, Gaoyue Guo, Lihong Mao, Zihan Yu, Xiaofei Fan et al. · 2022 · Portal hypertension & cirrhosis
49. Redefining Tissue Crosstalk via Shotgun Proteomic Analyses of Plasma Extracellular Vesicles
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50. Infection and chronic disease activate a brain-muscle signaling axis that regulates muscle performance
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51. Myokine Regulation of Insulin Secretion: Impact of Inflammation and Type 2 Diabetes
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52. Alpha-linolenic acid and linoleic acid differentially regulate the skeletal muscle secretome of obese Zucker rats
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53. Exercise, exerkines and exercise mimetic drugs: Molecular mechanisms and therapeutics.
    Vedant Samant, Arati Prabhu · 2024 · Life Science
54. Effect of treatment with conditioned media derived from C2C12 myotube on adipogenesis and lipolysis in 3T3-L1 adipocytes
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55. The association of sarcopenia, possible sarcopenia and cognitive impairment: A systematic review and meta-analysis
    Jiahui Huang, Min Li, Qi Luo, Jing Li · 2025 · PLoS ONE
56. May the Force and Mass Be With You—Evidence-Based Contribution of Mechano-Biological Descriptors of Resistance Exercise
    Claudio Viecelli, David Aguayo · 2022 · Frontiers in Physiology
57. Changes Induced by Aging and Long-Term Exercise and/or DHA Supplementation in Muscle of Obese Female Mice
    Alejandro Martínez-Gayo, Elisa Félix‐Soriano, Neira Sáinź, Pedro González‐Muniesa, María Jesús Moreno-Aliaga · 2022 · Nutrients
58. Review of the health-promoting effects of exercise and the involvement of myokines.
    Kazuhiro Nishii, Naoki Aizu, Kouji Yamada · 2023 · PubMed Central
59. Impact of moderate exercise on fatty acid oxidation in pancreatic β-cells and skeletal muscle
    A. Langlois, Alexis V. Forterre, M. Pinget, Karim Bouzakri · 2021 · Journal of Endocrinological Investigation
60. Downhill hiking improves low-grade inflammation, triglycerides, body weight and glucose tolerance
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61. Decorin, an exercise-induced secretory protein, is associated with improved prognosis in breast cancer patients but does not mediate anti-tumorigenic tissue crosstalk in mice
    Marit Hjorth, Casey L. Egan, Guilherme Defante Telles, Martin Pál, David Gallego‐Ortega, Oliver K Fuller, Emma D. McLennan, Ryan D. Gillis, Tae Gyu Oh, George E.O. Muscat et al. · 2024 · Journal of sport and health science/Journal of Sport and Health Science
62. High-intensity leg cycling alters the molecular response to resistance exercise in the arm muscles
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63. Myotonic Dystrophy and Developmental Regulation of RNA Processing
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64. Exercise serum increases GLUT4 in human adipocytes
    Marcelo Flores‐Opazo, Arthe Raajendiran, Matthew J. Watt, Mark Hargreaves · 2019 · Experimental Physiology
65. Eugenol mimics exercise to promote skeletal muscle fiber remodeling and myokine IL-15 expression by activating TRPV1 channel
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66. Molecular origin and biological effects of exercise mimetics
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67. A feeding-induced myokine modulates glucose homeostasis
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68. Divergent multiomic acute exercise responses reveal the impact of sex as a biological variable
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69. Benchside to the bedside of frailty and cardiovascular aging: Main shared cellular and molecular mechanisms
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70. Why Physical Activity Should Be Considered in Clinical Trials for COVID-19 Vaccines: A Focus on Risk Groups
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71. Effects of voluntary wheel running on mitochondrial content and dynamics in rat skeletal muscle
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72. Exercise, Exerkines, and Sarcopenia
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73. Exercise as a therapeutic intervention for long-lasting and chronic diseases
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74. Contribution of organokines in the development of NAFLD/NASH associated hepatocellular carcinoma
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75. What Muscle Signals Mediate the Beneficial Effects of Exercise on Cognition?
    Eduardo Elias Benarroch · 2022 · Neurology
76. Restoration of pharyngeal dilator muscle force in dystrophin‐deficient (mdx) mice following co‐treatment with neutralizing interleukin‐6 receptor antibodies and urocortin 2
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77. GeneXX: an online tool for the exploration of transcript changes in skeletal muscle associated with exercise.
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78. A Phenomic Perspective on Factors Influencing Breast Cancer Treatment: Integrating Aging and Lifestyle in Blood and Tissue Biomarker Profiling
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79. Myokine Responses to Exercise in a Rat Model of Low/High Adaptive Potential
    Wesam F. Farrash, Bethan Eileen Phillips, Steven L. Britton, Nathan Qi, Lauren G. Koch, Daniel James Wilkinson, Kenneth Smith, Philip James Atherton · 2021 · Frontiers in Endocrinology
80. The Role of Extracellular Vesicles in Musculoskeletal Diseases
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81. Physiology and technology for the ICU in vivo
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82. Musculoskeletal Aging, Sarcopenia, and Cancer
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83. A comparison of the acute physiological responses to BODYPUMP™ versus iso-caloric and iso-time steady state cycling
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84. Exercise serum regulates uric acid transporters in normal rat kidney cells
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85. Effects of a Circuit Training Program on Myokine Levels in Insulin‐Resistant Women: A Randomised Controlled Trial
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86. Exercise Induced-Cytokines Response in Marathon Runners: Role of ACE I/D and BDKRB2 +9/-9 Polymorphisms
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87. Global scientific trends in research of epigenetic response to exercise: A bibliometric analysis
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88. An exercise-linked mediator of memory protection
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89. Effect of exercise on tumor markers – Is exercise anti-tumorigenic in humans?: A scoping review of preliminary clinical investigations
    Dong‐Woo Kang, Oscar Barnes, Matthew G. Vander Heiden, Christina Marie Dieli-Conwright · 2022 · Critical Reviews in Oncology/Hematology
90. Association of the sarcopenia index with cognitive impairment in a middle-aged to older patients with acute ischemic stroke or transient ischemic attack: A multicenter cohort study
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91. Can microbes increase exercise performance in athletes?
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92. Plasma irisin and the brain-derived neurotrophic factor levels in sedentary subjects: effect of 8-weeks lifestyle intervention
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93. Exercise as medicine for survivors of paediatric cancer
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94. A comprehensive model for the converging biologies that underpin the homeostatic sleep signal
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95. Combined serum CTRP7 and CTRP15 levels as a novel biomarker for insulin resistance and type 2 diabetes mellitus
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96. Roles of natural products on myokines expression and secretion in skeletal muscle atrophy.
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97. Oncostatin M, a muscle-secreted myokine, recovers high-glucose-induced impairment of Akt phosphorylation by Fos induction in hippocampal neuron cells
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98. Insulin Infusion Is Linked to Increased NPPC Expression in Muscle and Plasma C-type Natriuretic Peptide in Male Dogs
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99. Heart failure-related skeletal myopathy. Potential involvement of myokines
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100. Exercise-Induced Myokines in Obesity-Related Metabolic Disorders and Cardiovascular Protection: A Narrative Review
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