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Lack of Exercise Is a Major Cause of Chronic Diseases

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Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

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Integrative Biology of Exercise

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Running-induced systemic cathepsin B secretion is associated with memory function

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Thermogenic Activation Induces FGF21 Expression and Release in Brown Adipose Tissue

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Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding

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Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry

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A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice

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Exosome-dependent Trafficking of HSP70

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Delivery of Therapeutic Proteins

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IL-4 Acts as a Myoblast Recruitment Factor during Mammalian Muscle Growth

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Suppression of body fat accumulation in myostatin-deficient mice

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Exercise as an anti-inflammatory therapy for rheumatic diseases—Myokine regulation

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Interleukin-6 Is a Novel Factor Mediating Glucose Homeostasis During Skeletal Muscle Contraction

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Fast/Glycolytic Muscle Fiber Growth Reduces Fat Mass and Improves Metabolic Parameters in Obese Mice

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Revisiting the matricellular concept

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Cancer, Physical Activity, and Exercise

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A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise

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Irisin – a myth rather than an exercise-inducible myokine

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Challenges in deriving high-confidence protein identifications from data gathered by a HUPO plasma proteome collaborative study

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Evidence against a Beneficial Effect of Irisin in Humans

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Decorin

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Acute Exercise Induces FGF21 Expression in Mice and in Healthy Humans

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AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise.

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Systems proteomics of liver mitochondria function

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Deep Proteomics of Mouse Skeletal Muscle Enables Quantitation of Protein Isoforms, Metabolic Pathways, and Transcription Factors*

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Skeletal myocytes are a source of interleukin‐6 mRNA expression and protein release during contraction: evidence of fiber type specificity

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Exercise-induced muscle-derived cytokines inhibit mammary cancer cell growth

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Signaling Specificity of Interleukin-6 Action on Glucose and Lipid Metabolism in Skeletal Muscle

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The Structure of Irisin Reveals a Novel Intersubunit β-Sheet Fibronectin Type III (FNIII) Dimer

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IL-7 is expressed and secreted by human skeletal muscle cells

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Initial Quantitative Proteomic Map of 28 Mouse Tissues Using the SILAC Mouse

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Irisin and FNDC5 in retrospect

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The myokine decorin is regulated by contraction and involved in muscle hypertrophy

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Pharmacologic Effects of FGF21 Are Independent of the “Browning” of White Adipose Tissue

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Enhanced growth of tumors in SPARC null mice is associated with changes in the ECM

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Low skeletal muscle mass is a strong predictive factor for surgical complications and a prognostic factor in oral cancer patients undergoing mandibular reconstruction with a free fibula flap

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Musclin, A Myokine Induced by Aerobic Exercise, Retards Muscle Atrophy During Cancer Cachexia in Mice

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The Protective Effect of Exercise in Neurodegenerative Diseases: The Potential Role of Extracellular Vesicles

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Inhibition of Human Lung Cancer Cell Proliferation and Survival by Post-Exercise Serum Is Associated with the Inhibition of Akt, mTOR, p70 S6K, and Erk1/2

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Exercise Training Improves Memory Performance in Older Adults: A Narrative Review of Evidence and Possible Mechanisms

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Follistatin-like 1 as a Novel Adipomyokine Related to Insulin Resistance and Physical Activity

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Irisin: An anti-inflammatory exerkine in aging and redox-mediated comorbidities

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Role of exercise-induced hepatokines in metabolic disorders

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Impact of Sarcopenia on Outcomes of Autologous Head and Neck Free Tissue Reconstruction

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Rac1 muscle knockout exacerbates the detrimental effect of high‐fat diet on insulin‐stimulated muscle glucose uptake independently of Akt

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Muscle-Derived Cytokines Reduce Growth, Viability and Migratory Activity of Pancreatic Cancer Cells

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Untitled work

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