The FGF family: biology, pathophysiology and therapy

Beenken, Andrew, Mohammadi, Moosa·2009·Nature Reviews Drug Discovery
DOI 10.1038/nrd2792

Cites (281)

Items 201–280 of 280

  1. Suramin, an Active Drug for Prostate Cancer: Interim Observations in a Phase I Trial
    Mario A. Eisenberger, L. M. Reyno, D. I. Jodrell, V. J. Sinibaldi, Katherine H. R. Tkaczuk, R N Sridhara, Eleanor G. Zuhowski, Mark H. Lowitt, S. C. Jacobs, Merrill J. Egorin · 1993 · JNCI Journal of the National Cancer Institute
  2. Increased expression of keratinocyte growth factor messenger RNA associated with inflammatory bowel disease
    PW Finch, Victor E. Pricolo, A Wu, SD Finkelstein · 1996 · Gastroenterology
  3. Antidepressant-like effects of intracerebroventricular FGF2 in rats
    Turner, Cortney A., Gula, Edny L., Taylor, Larry P., Watson, Stanley J., Akil, Huda · 2008 · Brain Research
  4. FGF-23–Klotho signaling stimulates proliferation and prevents vitamin D–induced apoptosis
    Damian Medici, Mohammed Shawkat Razzaque, Stephelynn DeLuca, Trent L. Rector, Bo Hou, Kihwa Kang, Regina M. Goetz, Moosa Mohammadi, Makoto Kuro‐o, Bjorn Reino Olsen et al. · 2008 · The Journal of Cell Biology
  5. Homozygous mutations in fibroblast growth factor 3 are associated with a new form of syndromic deafness characterized by inner ear agenesis, microtia, and microdontia.
    M. Tekin, B. Hismi, S. Fitoz, H. Özdağ, F. Cengiz, A. Sırmacı, Idil Aslan, B. Inceoğlu, E. B. Yüksel-Konuk, S. Yilmaz et al. · 2007 · American Journal of Human Genetics
  6. Inhibition of Fibroblast Growth Factor 19 Reduces Tumor Growth by Modulating β-Catenin Signaling
    Rama Pai, Debra Y. Dunlap, Jing Qing, Iman Mohtashemi, Kathy Hötzel, Dorothy M. French · 2008 · Cancer Research
  7. Physiological Regulation and Disorders of Phosphate Metabolism -Pivotal Role of Fibroblast Growth Factor 23-
    Seiji Fukumoto · 2008 · Internal Medicine
  8. Signaling, Internalization, and Intracellular Activity of Fibroblast Growth Factor
    Antoni Więdłocha, Vigdis Sørensen · 2004 · Current topics in microbiology and immunology
  9. Repifermin (keratinocyte growth factor‐2) for the treatment of active ulcerative colitis: a randomized, double‐blind, placebo‐controlled, dose‐escalation trial
    William J. Sandborn, Bruce E. Sands, Douglas C. Wolf, John F. Valentine, Michael A. Safdi, Seymour Katz, Kim L. Isaacs, Lawrence D. Wruble, Jeffry Katz, Daniel H. Present et al. · 2003 · Alimentary Pharmacology & Therapeutics
  10. Brain malformation in syndromic craniosynostoses, a primary disorder of white matter: a review
    Charles Raybaud, Concezio Di Rocco · 2007 · Child s Nervous System
  11. Plasma Concentrations of Fibroblast Growth Factors 19 and 21 in Patients with Anorexia Nervosa
    I Dostálová, Petra Kaválková, D Haluzíková, Z Lacinová, Miloš Mráz, Hana Papežová, Martin Haluzı́k · 2008 · The Journal of Clinical Endocrinology & Metabolism
  12. Towards a Resolution of the Stoichiometry of the Fibroblast Growth Factor (FGF)?FGF Receptor?Heparin Complex
    Nicholas J. Harmer, Leopold L. Ilag, Barbara Mulloy, Luca Pellegrini, Carol V. Robinson, Tom L. Blundell · 2004 · Journal of Molecular Biology
  13. Involvement of the FGFR4 Arg388 allele in head and neck squamous cell carcinoma
    Sylvia Streit, Johannes Bange, Alexander Fichtner, Stephan Ihrler, Wolfgang J. Issing, Axel Ullrich · 2004 · International Journal of Cancer
  14. Intracoronary and Intravenous Administration of Basic Fibroblast Growth Factor: Myocardial and Tissue Distribution
    Roger J. Laham, Mehrdad Rezaee, Mark J. Post, Frank William Sellke, Rene A. Braeckman, David Hung, Michael Simons · 1999 · Drug Metabolism and Disposition
  15. Mutations within the FGF5 gene are associated with hair length in cats
    Cord Drögemüller, Silvia Rüfenacht, Brigitta Annette Wichert, Tosso Leeb · 2007 · Animal Genetics
  16. FGF21: A Missing Link in the Biology of Fasting
    Marc L. Reitman · 2007 · Cell Metabolism
  17. Altered expression of keratinocyte growth factor and its receptor in psoriasis.
    Paul W. Finch, F Murphy, Irma R. Cardinale, James G. Krueger · 1997 · Europe PMC (PubMed Central)
  18. Conversion of cysteine to serine residues alters the activity, stability, and heparin dependence of acidic fibroblast growth factor.
    Sagrario Ortega, Marie‐Therese Schaeffer, D.D. Soderman, Jerry DiSalvo, David L. Linemeyer, Guillermo Giménez‐Gallego, Kenneth A. Thomas · 1991 · Journal of Biological Chemistry
  19. The fibroblast growth factor-binding protein FGF-BP.
    Shaker Abuharbeid, F. Czubayko, A. Aigner · 2006 · International Journal of Biochemistry and Cell Biology
  20. Genetic Transmission of Tumoral Calcinosis: Autosomal Dominant with Variable Clinical Expressivity*
    Kenneth W. Lyles, Ernest Jefferson Burkes, George J. Ellis, KATHERINE J. LUCAS, Edward A. Dolan, Marc K. Drezner · 1985 · The Journal of Clinical Endocrinology & Metabolism
  21. PI-88: a novel inhibitor of angiogenesis
    Ragini Reiney Kudchadkar, Rene C. Gonzalez, Karl D. Lewis · 2008 · Expert Opinion on Investigational Drugs
  22. Heparin Derivatives as Angiogenesis Inhibitors
    Marco Presta, Daria Leali, Helena Stabile, Roberto Ronca, Maura Camozzi, L. Coco, Emanuela Moroni, Sandra Liekens, Marco Rusnati · 2003 · Current Pharmaceutical Design
  23. Sequential changes in the expression of genes involved in lipid metabolism in adipose tissue and liver in response to fasting
    Mariona Palou, Teresa Priego, Juana Sánchez, E. Villegas, Ana María Rodríguez, Andreu Palou, Catalina Picó · 2008 · Pflügers Archiv - European Journal of Physiology
  24. Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury
    Angela Panoskaltsis‐Mortari, Patricia A. Taylor, Jeffrey S. Rubin, Aykut Üren, Lisbeth A. Welniak, William J. Murphy, Catherine L. Farrell, David L. Lacey, Bruce R. Blazar · 2000 · Blood
  25. Growth Factors in Bladder Wound Healing
    Laurence S. Baskin, Ronald S. Sutherland, Axel A. Thomson, Heip-Thieu Nguyen, Daniel McBurney Morgan, Simon W. Hayward, Yun Kit Hom, Michael DiSandro, Gerald R. Cunha · 1997 · The Journal of Urology
  26. Intracoronary basic fibroblast growth factor enhances myocardial collateral perfusion in dogs
    M. A. Sharmini Rajanayagam, Matie Shou, Venugopal Thirumurti, Daisy F. Lazarous, Arshed Ali Quyyumi, Lino Manuel Martins Gonçalves, Jonathan A. Stiber, Stephen E. Epstein, Ellis F. Unger · 2000 · Journal of the American College of Cardiology
  27. Preferential neurotrophic activity of fibroblast growth factor‐20 for dopaminergic neurons through fibroblast growth factor receptor‐1c
    Shigeki Ohmachi, Tadahisa Mikami, Morichika Konishi, Ayumi Miyake, Nobuyuki Itoh · 2003 · Journal of Neuroscience Research
  28. Insights from Angiogenesis Trials Using Fibroblast Growth Factor for Advanced Arteriosclerotic Disease
    Rohit Khurana, Michael Simons · 2003 · Trends in Cardiovascular Medicine
  29. The long and the short of it: evidence that FGF5 is a major determinant of canine ‘hair’‐itability
    Donna J. E. Housley, Patrick J. Venta · 2006 · Animal Genetics
  30. Spinal Cord Repair With Acidic Fibroblast Growth Factor as a Treatment for a Patient With Chronic Paraplegia
    Henrich Cheng, Kwong‐Kum Liao, Su-Fen Liao, Tien‐Yow Chuang, Yang‐Hsin Shih · 2004 · Spine
  31. Fibroblast growth factor (FGF)-4 can induce proliferation of cardiac cushion mesenchymal cells during early valve leaflet formation
    Yukiko Sugi, Naoki Ito, Györgyi Szebenyi, Kioina Myers, John F. Fallon, Takashi Mikawa, Roger R. Markwald · 2003 · Developmental Biology
  32. Suramin inhibits bFGF-induced endothelial cell proliferation and angiogenesis in the chick chorioallantoic membrane
    Romano Danesi, S Del Bianchi, Paola Soldani, A Campagni, Renato V. La Rocca, CE Myers, Antonio Paparelli, Mario Del Tacca · 1993 · British Journal of Cancer
  33. FGF6 in myogenesis
    Anne‐Sophie Armand, Iman Laziz, Christophe Chanoine · 2006 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  34. Correction of hypertension by normalization of endothelial levels of fibroblast growth factor and nitric oxide synthase in spontaneously hypertensive rats.
    Pedro Cuevas, M García-Calvo, Fernando Carceller, Diana Reimers, Mercedes Zazo, B. Cuevas, Isabel Muñoz‐Willery, V Martínez-Coso, Santiago Lamas, Guillermo Giménez‐Gallego · 1996 · Proceedings of the National Academy of Sciences
  35. Fibroblast Growth Factor 9 Secretion Is Mediated by a Non-cleaved Amino-terminal Signal Sequence*
    Jean-Michel Revest, Laurence DeMoerlooze, C. Dickson · 2000 · Journal of Biological Chemistry
  36. Fibroblast growth factor receptor 4 predicts failure on tamoxifen therapy in patients with recurrent breast cancer
    Daniëlle Meijer, Anieta M. Sieuwerts, Maxime P. Look, Ton van Agthoven, John A. Foekens, Lambert C. J. Dorssers · 2008 · Endocrine Related Cancer
  37. FGF-16 is required for embryonic heart development.
    Shun-Yan Lu, F. Sheikh, P. Sheppard, A. Fresnoza, M. L. Duckworth, Karen A. Detillieux, P. Cattini · 2008 · Biochemical and Biophysical Research Communications - BBRC
  38. Testing clinical therapeutic angiogenesis using basic fibroblast growth factor (FGF‐2)
    Ronnier J. Aviles, Brian Herb Annex, Robert J. Lederman · 2003 · British Journal of Pharmacology
  39. An FGF-binding protein (FGF-BP) exerts its biological function by parallel paracrine stimulation of tumor cell and endothelial cell proliferation through FGF-2 release
    Achim Michael Aigner, Moritz Butscheid, Philip Kunkel, Eberhard Krause, Katrin Lamszus, Anton Wellstein, Frank Czubayko · 2001 · International Journal of Cancer
  40. A Soluble Form of Fibroblast Growth Factor Receptor 2 (FGFR2) with S252W Mutation Acts as an Efficient Inhibitor for the Enhanced Osteoblastic Differentiation Caused by FGFR2 Activation in Apert Syndrome
    Yukiho Tanimoto, Masahiko Yokozeki, Kenji Hiura, Kazuya Matsumoto, Hideki Nakanishi, Toshio Matsumoto, Pierre J. Marie, Keiji Moriyama · 2004 · Journal of Biological Chemistry
  41. Does FGF23 toxicity influence the outcome of chronic kidney disease?
    Mohammed Shawkat Razzaque · 2008 · Nephrology Dialysis Transplantation
  42. Phase I/II Randomized Trial Evaluating the Safety and Clinical Effects of Repifermin Administered to Reduce Mucositis in Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation
    César O. Freytes, Voravit Ratanatharathorn, Charles Taylor, Camille N. Abboud, Nancy Chesser, Alejandro Restrepo, Jorge I. Arango, Daniel J. Odenheimer · 2004 · Clinical Cancer Research
  43. The fibroblast growth factor system is downregulated following social defeat
    Turner, Cortney A., Calvo, Nelson, Frost, Douglas O., Akil, Huda, Watson, Stanley J. · 2008 · Neuroscience Letters
  44. Biochemotherapy for the treatment of metastatic malignant melanoma: A systematic review
    Caroline M. Hamm, Shailendra Verma, Teresa M. Petrella, Kate Bak, Manya L. Charette · 2008 · Cancer Treatment Reviews
  45. Analysis of Mutations in Fibroblast Growth Factor (FGF) and a Pathogenic Mutation in FGF Receptor (FGFR) Provides Direct Evidence for the Symmetric Two-End Model for FGFR Dimerization
    Omar A. Ibrahimi, Brian K. Yeh, Anna V. Eliseenkova, Fuming Zhang, Shaun K. Olsen, Makoto Igarashi, Stuart A. Aaronson, Robert J. Linhardt, Moosa Mohammadi · 2005 · Molecular and Cellular Biology
  46. Fibroblast Growth Factor Receptor and Platelet-Derived Growth Factor Receptor Abnormalities in Eosinophilic Myeloproliferative Disorders
    Nicholas C.P. Cross, Andreas Reiter · 2008 · Acta Haematologica
  47. The discovery of α-Klotho and FGF23 unveiled new insight into calcium and phosphate homeostasis
    Y. Nabeshima · 2008 · Cellular and Molecular Life Sciences
  48. Nontoxic Doses of Suramin Enhance Activity of Doxorubicin in Prostate Tumors
    Yilong Zhang, SaeHeum Song, Fan Yang, Jessie L.‐S. Au, M. Guillaume Wientjes · 2001 · Journal of Pharmacology and Experimental Therapeutics
  49. Sustained low levels of fibroblast growth factor-1 promote persistent microvascular network formation
    Shiri Uriel, Eric Michael Brey, Howard P. Greisler · 2006 · The American Journal of Surgery
  50. Induction of FGF-7 after kidney damage: a possible paracrine mechanism for tubule repair
    Takaharu Ichimura, Paul W. Finch, G. Zhang, M Kan, James L. Stevens · 1996 · American Journal of Physiology-Renal Physiology
  51. Phase II trial of suramin in patients with advanced renal cell carcinoma: treatment results, pharmacokinetics, and tumor growth factor expression.
    Robert John Motzer, David M. Nanus, Paul V. O’Moore, Howard I. Scher, Dean F. Bajorin, Victor E. Reuter, William P. Tong, J Iversen, Carl Louison, Anthony P. Albino · 1992 · PubMed
  52. FGF-FGFR signaling in vertebrate organogenesis.
    Shigeaki Kato, Keisuke Sekine · 1999 · PubMed
  53. Fibroblast growth factor-1 prevents myocardial apoptosis triggered by ischemia reperfusion injury.
    Pedro Cuevas, Diana Reimers, Fernando Carceller, V Martínez-Coso, Mariano Redondo‐Horcajo, Iñigo Sáenz de Tejada, Guillermo Giménez‐Gallego · 1997 · PubMed
  54. Pharmacokinetics and Pharmacodynamics of Recombinant FGF‐2 in a Phase I Trial in Coronary Artery Disease
    Mark Bush, Emil E. Samara, M.J. Whitehouse, CARL N. YOSHIZAWA, Deborah L. Novicki, Marilyn C. Pike, Roger J. Laham, Michael Simons, Nicolas A.F. Chronos · 2001 · The Journal of Clinical Pharmacology
  55. A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis.
    Shoji Ichikawa, Erik Allen Imel, Mary L. Kreiter, Xijie Yu, Donald S. Mackenzie, Andrea H. Sorenson, Regina M. Goetz, Moosa Mohammadi, Kenneth E. White, Michael J. Econs · 2007 · PubMed
  56. Clinical trials of antiangiogenic agents
    Michael Hawkins · 1995 · Current Opinion in Oncology
  57. Immunohistochemical analysis of keratinocyte growth factor and fibroblast growth factor 10 expression in psoriasis
    Daniela Kovacs, Mario Falchi, Giorgia Cardinali, Salvatore Raffa, M. Carducci, Carlo Cota, Ada Amantea, Maria Rosaria Torrisi, Mauro Picardo · 2005 · Experimental Dermatology
  58. Myocardial ischemia enhances the expression of acidic fibroblast growth factor in human pericardial fluid
    Atsushi Iwakura, Masatoshi Fujita, Masaki Ikemoto, Koji Hasegawa, Ryuji Nohara, S Sasayama, Shoichi Miyamoto, Ario Yamazato, Keiichi Tambara, Masashi Komeda · 2000 · Heart and Vessels
  59. FGF2 in asthmatic airway-smooth-muscle-cell hyperplasia
    Ynuk Bossé, Marek Rola‐Pleszczynski · 2007 · Trends in Molecular Medicine
  60. FGF-2 Dependent Angiogenesis is a Latent Phenotype in Basic Fibroblast Growth Factor Transgenic Mice
    D L Fulgham, S.-R. Widhalm, Stacey L. Martin, J. Douglas Coffin · 1999 · Endothelium
  61. Cell kinetic studies in the murine ventral tongue epithelium: mucositis induced by radiation and its protection by pretreatment with keratinocyte growth factor (KGF)
    Christopher S. Potten, Dawn Booth, N. J. Cragg, Gregory L. Tudor, Julie A. O'Shea, Catherine E. Booth, Frank Meineke, Dieter Barthel, Markus Loeffler · 2002 · Cell Proliferation
  62. FGFR3 Mutations in Benign Skin Tumors
    C. Hafner, T. Vogt, A. Hartmann · 2006 · Cell Cycle
  63. Nordihydroguaiaretic Acid Inhibits an Activated FGFR3 Mutant, and Blocks Downstream Signaling in Multiple Myeloma Cells
    April N. Meyer, Christopher W. McAndrew, D. Donoghue · 2008 · Cancer Research
  64. A neutralizing anti‐fibroblast growth factor (FGF) 8 monoclonal antibody shows anti‐tumor activity against FGF8b‐expressing LNCaP xenografts in androgen‐dependent and ‐independent conditions
    Kumiko Maruyama‐Takahashi, Naoki Shimada, Teruyoshi Imada, Yoshimi Maekawa‐Tokuda, Toshihiko Ishii, Jun Ouchi, Hideaki Kusaka, Hiromasa Miyaji, Shiro Akinaga, Akira Tanaka et al. · 2008 · The Prostate
  65. Antitumor activity of fibroblast growth factor receptor 3–specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis
    Jorge Luis Martinez-Torrecuadrada, Lawrence H. Cheung, Paula López-Serra, Rodrigo Barderas, Marta Cañamero, Sergio Ferreiro, Michael G. Rosenblum, José Ignacio Casal · 2008 · Molecular Cancer Therapeutics
  66. Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus β-Strand Interactions
    Vikash Kumar Dubey, Jihun Lee, Thayumanasamy Somasundaram, Sachiko I. Blaber, Michael Blaber · 2007 · Journal of Molecular Biology
  67. Effect of Recombinant Human Keratinocyte Growth Factor (rHuKGF) on the Immunopathogenesis of Intestinal Graft-Vs.-Host Disease Induced Without a Preconditioning Regimen
    Cynthia A. Ellison, Shannon A. Natuik, Jacqie M. M. Fischer, Alan R. McIntosh, Sheila A. Scully, Eric J. Bow, Dimitry M. Danilenko, Kent T. HayGlass, John G. Gartner · 2004 · Journal of Clinical Immunology
  68. The Effect of Palifermin on Chemotherapyand Radiation Therapy–Induced Mucositis: A Review of the Current Literature
    Anne Beaven, Thomas C. Shea · 2007 · Supportive Cancer Therapy
  69. Modulation of Metabolic Syndrome by Fibroblast Growth Factor 19 (FGF19)?
    Alison M. Strack, Robert Walter Myers · 2004 · Endocrinology
  70. Intravesical suramin: a novel agent for the treatment of superficial transitional-cell carcinoma of the bladder
    McClellan M. Walther, William Douglas Figg, William Marston Linehan · 1996 · World Journal of Urology
  71. A Neutralizing Anti–Fibroblast Growth Factor 8 Monoclonal Antibody Shows Potent Antitumor Activity against Androgen-Dependent Mouse Mammary Tumors In vivo
    Naoki Shimada, Toshihiko Ishii, Teruyoshi Imada, Katsumi Takaba, Yuka Sasaki, Kumiko Maruyama‐Takahashi, Yoshimi Maekawa‐Tokuda, Hideaki Kusaka, Shiro Akinaga, Akira Tanaka et al. · 2005 · Clinical Cancer Research
  72. Safety and tolerability of velafermin (CG53135-05) in patients receiving high-dose chemotherapy and autologous peripheral blood stem cell transplant
    Michael W. Schuster, Tsiporah B. Shore, John G. Harpel, June Greenberg, Bita Jalilizeinali, Scott Possley, Robert W. Gerwien, William F. Hahne, Yuan‐Di C. Halvorsen · 2007 · Supportive Care in Cancer
  73. Functional recovery of chronic complete idiopathic transverse myelitis after administration of neurotrophic factors
    P-H Lin, T-Y Chuang, Liao Kk, Henrich Cheng, Y-S Shih · 2005 · Spinal Cord
  74. Tumor-induced rickets: usefulness of MR gradient echo recall imaging for tumor localization
    Dorothy I. Shulman, Gregory V. Hahn, Richard M. Benator, Kenneth Washington, Kenneth E. White, Joshua Farber, Michael J. Econs · 2004 · The Journal of Pediatrics
  75. Spinal Cord Implantation with Acidic Fibroblast Growth Factor as a Treatment for Root Avulsion in Obstetric Brachial Plexus Palsy
    Pei-Hsin Lin, Henrich Cheng, Wen‐Cheng Huang, Tien‐Yow Chuang · 2005 · Journal of the Chinese Medical Association
  76. Cell kinetic studies in the murine ventral tongue epithelium: the effects of repeated exposure to keratinocyte growth factor
    Christopher S. Potten, Dawn Booth, N. J. Cragg, Julie A. O'Shea, Gregory L. Tudor, Catherine E. Booth · 2002 · Cell Proliferation
  77. Palifermin in allogeneic HSCT: many questions remain
    Walter J. F. M. van der Velden, Alexandra H. E. Herbers, Nicole M. A. Blijlevens · 2008 · Bone Marrow Transplantation
  78. Alferminogene tadenovec, an angiogenic FGF4 gene therapy for coronary artery disease.
    Aidan W. Flynn, Timothy O’Brien · 2008 · PubMed
  79. Therapeutic Angiogenesis Gains a Leg to Stand On
    Andreas Rück, Christer Sylvén · 2008 · Molecular Therapy
  80. Untitled work
    1999 · 10.1002/(sici)1098-1004(1999)14:2