Cited by 1,167Blood Pressure and Hypertension StudiesSodium Intake and HealthCardiovascular Health and Disease Prevention

The DOI matches its Crossref record; 214 of the 215 references it cites were found in a registry or an index.

Hypertension.

Open access

Oparil, Suzanne, Acelajado, Maria Czarina, Bakris, George L., Berlowitz, Dan R., Cífková, Renata, Dominiczak, Anna F., Grassi, Guido, Jordan, Jens, Poulter, Neil R., Rodgers, Anthony, Whelton, Paul K.·2018·Nature Reviews Disease Primers

DOI 10.1038/nrdp.2018.14PMC PMC6477925

Open this paper in CoChat — free account

Abstract

Systemic arterial hypertension is the most important modifiable risk factor for all-cause morbidity and mortality worldwide and is associated with an increased risk of cardiovascular disease (CVD). Fewer than half of those with hypertension are aware of their condition, and many others are aware but not treated or inadequately treated, although successful treatment of hypertension reduces the global burden of disease and mortality. The aetiology of hypertension involves the complex interplay of environmental and pathophysiological factors that affect multiple systems, as well as genetic predisposition. The evaluation of patients with hypertension includes accurate standardized blood pressure (BP) measurement, assessment of the patients' predicted risk of atherosclerotic CVD and evidence of target-organ damage, and detection of secondary causes of hypertension and presence of comorbidities (such as CVD and kidney disease). Lifestyle changes, including dietary modifications and increased physical activity, are effective in lowering BP and preventing hypertension and its CVD sequelae. Pharmacological therapy is very effective in lowering BP and in preventing CVD outcomes in most patients; first-line antihypertensive medications include angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, dihydropyridine calcium-channel blockers and thiazide diuretics.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1038/nrdp.2018.14

Cites

214 of 214 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., Mattheus, M., Devins, T., Johansen, O. E., Woerle, H. J., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1504720 · Cited by 12,315
Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies
(2002) · The Lancet · doi:10.1016/s0140-6736(02)11911-8 · Cited by 10,266
Global burden of hypertension: analysis of worldwide data
Kearney, P. M., Whelton, M., Reynolds, K., Muntner, P., Whelton, P. K., & He, J. (2005) · The Lancet · doi:10.1016/s0140-6736(05)17741-1 · Cited by 8,698
Self-citation
2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)
James, P. A., Oparil, S., Carter, B. L., Cushman, W. C., Dennison-Himmelfarb, C., Handler, J., Lackland, D. T., LeFevre, M. L., MacKenzie, T. D., Ogedegbe, O., et al. (2014) · JAMA · doi:10.1001/jama.2013.284427 · Cited by 7,950
Self-citation
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
Forouzanfar, M. H., Afshin, A., Alexander, L. T., Anderson, H. R., Bhutta, Z. A., Biryukov, S., Brauer, M., Burnett, R., Cercy, K., Charlson, F. J., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31679-8 · Cited by 7,698
Intravenous Fluids and Acute Kidney Injury
Ding, X., Cheng, Z., & Qian, Q. (2017) · Blood Purification · doi:10.1159/000452702 · Cited by 6,869
A Randomized Trial of Intensive versus Standard Blood-Pressure Control
The SPRINT Research Group (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1511939 · Cited by 6,325
A Clinical Trial of the Effects of Dietary Patterns on Blood Pressure
Appel, L. J., Moore, T. J., Obarzanek, E., Vollmer, W. M., Svetkey, L. P., Sacks, F. M., Bray, G. A., Vogt, T. M., Cutler, J. A., Windhauser, M. M., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704173361601 · Cited by 5,981
2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
Mancia, G., Fagard, R., Narkiewicz, K., Redón, J., Zanchetti, A., Böhm, M., Christiaens, T., Cifkova, R., De Backer, G., Dominiczak, A., et al. (2013) · Journal of Hypertension · doi:10.1097/01.hjh.0000431740.32696.cc · Cited by 5,655
Self-citation
Effects on Blood Pressure of Reduced Dietary Sodium and the Dietary Approaches to Stop Hypertension (DASH) Diet
Sacks, F. M., Svetkey, L. P., Vollmer, W. M., Appel, L. J., Bray, G. A., Harsha, D., Obarzanek, E., Conlin, P. R., Miller, E. R., Simons-Morton, D. G., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200101043440101 · Cited by 5,638

Flagged first, then by citations

Show all 215 references

1 of the 215 references couldn’t be matched to a known paper.

Research works printed but not linked: 3

Johnson, K. C. et al. Blood pressure measurement in the Systolic Blood Pressure Intervention Trial (SPRINT). Hypertension (in the press).
Whelton, P. K. Epidemiology and the Prevention of Hypertension. J. Clin. Hypertens. 6, 636–642 (2004). · DOI
American Diabetes Association. Standards of medical care in diabetes — 2017. Diabetes Care 40 (Suppl. 1), S1–S142 (2017).

Sorted by citations

Items 301–400 of 1,000

Evaluation of Pharmacokinetic Interactions Between the New SGLT2 Inhibitor SHR3824 and Valsartan in Healthy Chinese Volunteers
Huang, Y., Liu, R., Wang, Y., Liu, G., Wang, C., Chen, X., Jia, Y., & Shen, J. (2022) · Clinical Therapeutics · doi:10.1016/j.clinthera.2022.06.001 · Cited by 14
Deeper insight into the role of IL-17 in the relationship beween hypertension and intestinal physiology
Yang, Z., Wang, T., Wang, B., Gao, H., He, C., Shang, H., Lü, X., Wang, Y., & Xu, J. (2022) · Journal of Inflammation · doi:10.1186/s12950-022-00311-0 · Cited by 15
Protein Hydrolysates from Brewing By-Products as Natural Alternatives to ACE-Inhibitory Drugs for Hypertension Management
Ribeiro-Oliveira, R., Martins, Z. E., Faria, M. Â., Sousa, J. B., Ferreira, I. M. P. L. V. O., & Diniz, C. (2022) · Life · doi:10.3390/life12101554 · Cited by 14
Non-Invasive Ultrasound Modulation of Solitary Tract Nucleus Exerts a Sustainable Antihypertensive Effect in Spontaneously Hypertensive Rats
Cao, F., Zhang, J., Li, D., Wang, M., Lai, C., Xu, T., Bouakaz, A., Ren, P., Wan, M., Han, J., et al. (2022) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2022.3231343 · Cited by 14
Food-derived Bioactive Peptides with Angiotensin-Converting Enzyme Inhibiting Effect: A Systematic Review
Daza-Rodríguez, B., Martínez, A. R., Padilla, A. M., & Lázaro, J. P. M. (2023) · Journal of Pharmacology and Pharmacotherapeutics · doi:10.1177/0976500x231175217 · Cited by 14
Vascular multiple sclerosis: addressing the pathogenesis, genetics, pro-angiogenic factors, and vascular abnormalities, along with the role of vascular intervention
Prajjwal, P., Shree, A., Das, S., Inban, P., Ghosh, S., Senthil, A., Gurav, J., Kundu, M., Marsool, M. D. M., Gadam, S., et al. (2023) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000001177 · Cited by 14
VEGFC ameliorates salt-sensitive hypertension and hypertensive nephropathy by inhibiting NLRP3 inflammasome via activating VEGFR3-AMPK dependent autophagy pathway
Wu, Q., Meng, W., Zhu, B., Chen, X., Fu, J., Zhao, C., Liu, G., Luo, X., Lv, Y., Zhao, W., et al. (2023) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-023-04978-3 · Cited by 14
Zilebesiran: A Promising Antihypertensive Therapy Inhibiting Angiotensinogen Synthesis
Khan, R. S., & Frishman, W. H. (2024) · Cardiology in Review · doi:10.1097/crd.0000000000000645 · Cited by 14
Identification of novel hypertension biomarkers using explainable AI and metabolomics
Sekaran, K., & Zayed, H. (2024) · Metabolomics · doi:10.1007/s11306-024-02182-3 · Cited by 14
Angiotensin‐converting enzyme inhibitor and angiotensin II type 1 receptor blocker: Potential agents to reduce post‐surgical scar formation in humans
Hu, Y., Fang, Q., Wang, X., Zhao, W., Zheng, B., Zhang, D. K., & Tan, W. (2020) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.13458 · Cited by 14
Systemic arterial hypertension and cognition in adults: effects on executive functioning
Moraes, N. C., Muela, H. C. S., Memória, C. M., Costa‐Hong, V., Machado, M. F., Cecchini, M. A., Nitríni, R., Bortolotto, L. A., & Yassuda, M. S. (2020) · Arquivos de Neuro-Psiquiatria · doi:10.1590/0004-282x20200039 · Cited by 14
Ultrafine particles, blood pressure and adult hypertension: a population-based survey in Northeast China
Lin, L., Gao, M. C., Xiao, X., Knibbs, L. D., Morawska, L., Dharmage, S. C., Heinrich, J., Jalaludin, B. B., Lin, S., Guo, Y., et al. (2021) · Environmental Research Letters · doi:10.1088/1748-9326/ac1c28 · Cited by 14
APOE Genetic Polymorphism rs7412 T/T Genotype May Be a Risk Factor for Essential Hypertension among Hakka People in Southern China
Rao, H., Wu, H., Yu, Z., & Huang, Q. (2022) · International Journal of Hypertension · doi:10.1155/2022/8145896 · Cited by 14
Novel antihypertensive agents for resistant hypertension: what does the future hold?
Salvador, V. D., & Bakris, G. L. (2022) · Hypertension Research · doi:10.1038/s41440-022-01025-9 · Cited by 13
Self-citation
Screen-printed carbon electrode/natural silica-ceria nanocomposite for electrochemical aptasensor application
Zakiyyah, S. N., Eddy, D. R., Firdaus, M. L., Subroto, T., & Hartati, Y. W. (2022) · Journal of Electrochemical Science and Engineering · doi:10.5599/jese.1455 · Cited by 14
Evaluation of the Safety and Efficacy of Dual Therapy Perindopril/Amlodipine in the Management of Hypertension. A Systematic Review and Meta-Analysis
Mostafa, S., Shabana, H., Khalil, F., mancy, I. M. E., Zedan, H. A.-M., Elmoursi, A., Ramadan, I. G., Mohamed, S. E. D., Kassem, A., & Kamel, I. S. (2022) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-022-00544-3 · Cited by 14
Associations between Plasma Essential Metals Levels and the Risks of All-Cause Mortality and Cardiovascular Disease Mortality among Individuals with Type 2 Diabetes
Li, Z., Wang, R., Long, T., Xu, Y., Guo, H., Zhang, X., & He, M. (2023) · Nutrients · doi:10.3390/nu15051198 · Cited by 14
Early-Stage Dynamics in Vascular Endothelial Cells Exposed to Hydrostatic Pressure
Yoshino, D., & Sato, M. (2019) · Journal of Biomechanical Engineering · doi:10.1115/1.4044046 · Cited by 14
Heavy metals as environmental risk factors for cardiovascular diseases: from the perspective of the renin angiotensin aldosterone system and oxidative stress
Akther, J., Nabi, A. H. M. N., & Ebihara, A. (2019) · Reviews in Agricultural Science · doi:10.7831/ras.7.0_68 · Cited by 14
Targeting a systolic blood pressure of <130 mmHg is beneficial in adults with hypertension aged ≥75 years: a systematic review and meta-analysis
Nozato, Y., Nohara‐Shitama, Y., Kubozono, T., Akasaka, H., Takami, Y., Arima, H., Sakima, A., & Yamamoto, K. I. (2025) · Hypertension Research · doi:10.1038/s41440-025-02302-z · Cited by 13
Interactions between the intrarenal dopaminergic and the renin–angiotensin systems in the control of systemic arterial pressure
de Castro, P. A. S. V., José, P. A., & Silva, A. C. S. E. (2022) · Clinical Science · doi:10.1042/cs20220338 · Cited by 13
Dosing time optimization of antihypertensive medications by including the circadian rhythm in pharmacokinetic-pharmacodynamic models
Cortés‐Ríos, J., Hermida, R. C., & Rodriguez-Fernández, M. (2022) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1010711 · Cited by 13
Role of G-Proteins and GPCRs in Cardiovascular Pathologies
Kaur, G., Verma, S. K., Singh, D. K., & Singh, N. K. (2023) · Bioengineering · doi:10.3390/bioengineering10010076 · Cited by 19
The sustainable antihypertensive and target organ damage protective effect of transcranial focused ultrasound stimulation in spontaneously hypertensive rats
Li, D., Cao, F., Han, J., Wang, M., Lai, C., Zhang, J., Xu, T., Bouakaz, A., Wan, M., Ren, P., et al. (2023) · Journal of Hypertension · doi:10.1097/hjh.0000000000003407 · Cited by 13
Mitochondrial Damage and Hypertension: Another Dark Side of Sodium Excess
Afşar, B., & Afşar, R. E. (2023) · Current Nutrition Reports · doi:10.1007/s13668-023-00486-9 · Cited by 13
Association between plain water intake and risk of hypertension: longitudinal analyses from the China Health and Nutrition Survey
Li, S., Xiao, X., & Zhang, X. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1280653 · Cited by 19
Definition, prevalence, and economic impacts of hypertension on the elderly population
Lien, C.-W., Lee, Y., Lu, C., Chang, Y.-C., Lin, Y., Cheng, H., Chen, M. Y., Lee, L., Huang, C.-K., Lin, Y., et al. (2025) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2025.02.020 · Cited by 22
Association of metabolic syndrome with cardiovascular outcomes in hypertensive patients: a systematic review and meta-analysis
Liu, J., Chen, Y., Cai, K., & Gong, Y. (2021) · Journal of Endocrinological Investigation · doi:10.1007/s40618-021-01603-7 · Cited by 13
The hypothalamus and its role in hypertension
Goncharuk, V. D. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-819973-2.00023-x · Cited by 13
Relationship Between Occupational Noise and Hypertension in Modern Enterprise Workers: A Case–Control Study
Zhou, B., Lan, Y., Bi, Y., Li, C., Zhang, X., & Wu, X. (2022) · International Journal of Public Health · doi:10.3389/ijph.2022.1604997 · Cited by 13
Age‐related deficits in neuronal physiology and cognitive function are recapitulated in young mice overexpressing the L‐type calcium channel, CaV1 .3
Moore, S. J., Cazares, V. A., Temme, S. J., & Murphy, G. G. (2023) · Aging Cell · doi:10.1111/acel.13781 · Cited by 12
The effect of short-term perindopril and telmisartan treatment on circulating levels of anti-inflammatory cytokines in hypertensive patients
Gilowski, W., Krysiak, R. G., Marek, B., & Okopień, B. (2018) · Endokrynologia Polska · doi:10.5603/ep.a2018.0068 · Cited by 13
Multistate Markov model application for blood pressure transition among the Chinese elderly population: a quantitative longitudinal study
Zheng, X., Xiong, J., Zhang, Y., Xu, L., Zhou, L., Zhao, B., & Wang, Y. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-059805 · Cited by 13
Uncovering antiobesity-related hypertension targets and mechanisms of metformin, an antidiabetic medication
Yang, L., Yang, J., Xiao, L., Huang, W., Zhang, X., & Li, R. (2021) · Bioengineered · doi:10.1080/21655979.2021.1954581 · Cited by 12
Ellagic Acid prevents vascular dysfunction in small mesenteric arteries of ovariectomized hypertensive rats
da Silva, F. B., Romero, W. G., Rouver, W. D. N., Silva, K., de Almeida, S. A., Mengal, V., Peluso, A. A., Endlich, P. W., Bissoli, N. S., Claudio, E. R. G., et al. (2022) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2022.108995 · Cited by 12
Association of Urinary Strontium with Cardiovascular Disease Among the US Adults: A Cross-Sectional Analysis of the National Health and Nutrition Examination Survey
Wang, S., Sun, J., Gu, L., Wang, Y., Du, C., Wang, H., Ma, Y., & Wang, L. (2022) · Biological Trace Element Research · doi:10.1007/s12011-022-03451-9 · Cited by 12
Epigenetic Signatures in Arterial Hypertension: Focus on the Microvasculature
Mengozzi, A., Costantino, S., Mongelli, A., Mohammed, S. A., Gorica, E., Delfine, V., Masi, S., Virdis, A., Ruschitzka, F. T., & Paneni, F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054854 · Cited by 13
Major depressive disorder increased the risk of hypertension: A Mendelian randomization study
Zhang, X., & Li, C. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.03.144 · Cited by 16
The association between sleep duration and cardiometabolic risk among children and adolescents in the United States (US): A NHANES study
Morgan, T., Basalely, A. M., Singer, P. S., Castellanos, L., & Sethna, C. B. (2024) · Child Care Health and Development · doi:10.1111/cch.13273 · Cited by 14
Clinical and molecular insights into cardiovascular disease in psoriatic patients and the potential protective role of apremilast
Barbarroja, N., López‐Medina, C., Escudero‐Contreras, A., & de la Rosa, I. A. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1459185 · Cited by 12
Association of periodontitis with cardiovascular and all-cause mortality in hypertensive individuals: insights from a NHANES cohort study
Li, J., Yao, Y., Yin, W., Feng, S., Yan, P., Wang, L., Xiao, Z., Zhang, K., Tian, J., Wang, Z., et al. (2024) · BMC Oral Health · doi:10.1186/s12903-024-04708-6 · Cited by 12
Recent advancements in targeting the immune system to treat hypertension
Muralitharan, R. R., Marques, F. Z., & O’Donnell, J. A. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.177008 · Cited by 14
Antibiotic-induced gut dysbiosis: unraveling the gut-heart axis and its impact on cardiovascular health
Kaur, N., Kumar, P., Dhami, M., & Aran, K. R. (2025) · Molecular Biology Reports · doi:10.1007/s11033-025-10425-2 · Cited by 13
“Gut Microbiota as a Therapeutic Target for Hypertension: Challenges and Insights for Future Clinical Applications” “Gut Microbiota and Hypertension Therapy”
Mahgoup, E. M. (2025) · Current Hypertension Reports · doi:10.1007/s11906-025-01331-w · Cited by 14
Bioactive Peptides and Hydrolysates from Egg Proteins as a New Tool for Protection Against Cardiovascular Problems
Miguel, M., Vassallo, D. V., & Wiggers, G. A. (2020) · Current Pharmaceutical Design · doi:10.2174/1381612826666200327181458 · Cited by 12
Associations of Renin‐Angiotensin System Antagonist Medication Adherence and Economic Outcomes Among Commercially Insured US Adults: A Retrospective Cohort Study
Campbell, P. J., Axon, D. R., Taylor, A. M., Pickering, M. K., Black, H. L., Warholak, T. L., & Chinthammit, C. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.119.016094 · Cited by 13
Antioxidant Properties of Egg White Hydrolysate Prevent Mercury-Induced Vascular Damage in Resistance Arteries
Escobar, A. G., Rizzetti, D. A., Piagette, J. T., Peçanha, F. M., Vassallo, D. V., Miguel, M., & Wiggers, G. A. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.595767 · Cited by 12
Extra Virgin Olive Oil Phenols Vasodilate Rat Mesenteric Resistance Artery via Phospholipase C (PLC)-Calcium Microdomains-Potassium Channels (BKCa) Signals
D’Agostino, R., Barberio, L., Gatto, M., Tropea, T., Luca, M. D., & Mandalà, M. (2021) · Biomolecules · doi:10.3390/biom11020137 · Cited by 13
Proteomic and Structural Manifestations of Cardiomyopathy in Rat Models of Obesity and Weight Loss
Liśkiewicz, A., Marczak, Ł., Bogus, K., Liśkiewicz, D., Przybyła, M., & Lewin‐Kowalik, J. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.568197 · Cited by 12
Mining Important Herb Combinations of Traditional Chinese Medicine against Hypertension Based on the Symptom-Herb Network Combined with Network Pharmacology
Sun, Z., Xu, Y., An, W., Bi, S., Xu, S., Zhang, R., Cong, M., & Chen, S. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/5850899 · Cited by 12
Predicting High Blood Pressure Using DNA Methylome-Based Machine Learning Models
Nguyen, M., Le, H. L., Hwang, K., Hong, Y., & Kim, J. H. (2022) · Biomedicines · doi:10.3390/biomedicines10061406 · Cited by 12
Concurrent dietary intake to nitrate, thiocyanate, and perchlorate is negatively associated with hypertension in adults in the USA
Xu, D., Zhu, X., Xie, X., Huang, C., Fang, X., & Yin, T. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-23093-7 · Cited by 12
Mathematical modeling of antihypertensive therapy
Kutumova, E. O., Kiselev, I. N., Sharipov, R., Израйлевна, Л. Г., & Kolpakov, F. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.1070115 · Cited by 13
Diabetes, Hypertension, and Comorbidity among Bangladeshi Adults: Associated Factors and Socio-Economic Inequalities
Kundu, S., Rahman, M. A., Kabir, H., Banna, M. H. A., Hagan, J. E., Srem‐Sai, M., & Wang, L. (2022) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd10010007 · Cited by 12
Arterial hypertension in patients with takotsubo syndrome: prevalence, long-term outcome, and secondary preventive strategies: a report from the Takotsubo Italian Network register
Silverio, A., Bossone, E., Parodi, G., Scudiero, F., Maio, M. D., Vriz, O., Bellino, M., Zito, C., Provenza, G., Iuliano, G., et al. (2023) · European Journal of Preventive Cardiology · doi:10.1093/eurjpc/zwad237 · Cited by 12
Association Between Stress and Coping with DNA Methylation of Blood Pressure-Related Genes Among African American Women
Brown, K., Hui, Q., Huang, Y., Taylor, J. Y., Prescott, L., Barcelona, V., Crusto, C. A., & Sun, Y. V. (2019) · Chronic Stress · doi:10.1177/2470547019879088 · Cited by 14
Implication of Opioid Receptors in the Antihypertensive Effect of a Novel Chicken Foot-Derived Peptide
Mas‐Capdevila, A., Iglesias‐Carres, L., Arola‐Arnal, A., Aragonès, G., Muguerza, B., & Bravo, F. I. (2020) · Biomolecules · doi:10.3390/biom10070992 · Cited by 12
Impact of Sex and Pathophysiology on Optimal Drug Choice in Hypertensive Rats: Quantitative Insights for Precision Medicine
Ahmed, S., Sullivan, J. C., & Layton, A. T. (2020) · iScience · doi:10.1016/j.isci.2021.102341 · Cited by 11
A Computational Method for Learning Disease Trajectories From Partially Observable EHR Data
Oh, W., Steinbach, M. S., Castro, M. R., PETERSON, K. A., Kumar, V., Caraballo, P. J., & Simon, G. (2021) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2021.3089441 · Cited by 11
Effects of Three Traditional Chinese Fitness Exercises Combined with Antihypertensive Drugs on Patients with Essential Hypertension: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Dai, L., Jiang, Y., Wang, P., & Chen, K. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/2570472 · Cited by 14
Nutraceuticals in the Management of Cardiovascular Risk Factors: Where is the Evidence?
Russell, C., Keshavamurthy, S., & Saha, S. P. (2021) · Cardiovascular & Haematological Disorders - Drug Targets · doi:10.2174/1871529x21666211201104124 · Cited by 12
Effects of the Mindfulness-Based Blood Pressure Reduction (MB-BP) program on depression and neural structural connectivity
Polcari, J. J., Cali, R. J., Nephew, B. C., Lu, S., Rashkovskii, M., Wu, J., Saadeh, F., Loucks, E., & King, J. A. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.05.059 · Cited by 13
Factors associated with nonadherence to antihypertensive medication among middle-aged adults with hypertension: findings from the Taiwan National Health Interview Survey
Chou, C.-P., Chen, C., Huang, K.-S., Lin, S., Huang, C.-F., & Koo, M. (2020) · Journal of International Medical Research · doi:10.1177/0300060520936176 · Cited by 11
Atomistic simulations suggest dietary flavonoids from Beta vulgaris (beet) as promising inhibitors of human angiotensin-converting enzyme and 2-alpha-adrenergic receptors in hypertension
Adetunji, J. A., Ogunyemi, O. M., Gyebi, G. A., Adewumi, A. E., & Olaiya, C. O. (2023) · Bioinformatics Advances · doi:10.1093/bioadv/vbad133 · Cited by 12
Unilateral chemical ablation of the adrenal gland lowers blood pressure and alleviates target organ damage in spontaneously hypertensive rats
Wang, X., Luo, T., Yang, Y., Zhou, Y., Hou, J., & Wang, P. (2023) · Hypertension Research · doi:10.1038/s41440-023-01444-2 · Cited by 11
Hypertension combined with limitations in activities of daily living and the risk for cardiovascular disease
Li, Y., Jiang, M., Ren, X., Han, L., Zheng, X., & Wu, W. (2024) · BMC Geriatrics · doi:10.1186/s12877-024-04832-6 · Cited by 11
Hemodynamic Bedside Monitoring Instrument with Pressure and Optical Sensors: Validation and Modality Comparison
Kaisti, M., Panula, T., Sirkiä, J., Pänkäälä, M., Koivisto, T., Niiranen, T., & Kantola, I. M. (2024) · Advanced Science · doi:10.1002/advs.202307718 · Cited by 11
Mathematical modelling of the influence of ACE I/D polymorphism on blood pressure and antihypertensive therapy
Kutumova, E. O., Kovaleva, A. Y., Sharipov, R., Израйлевна, Л. Г., & Kolpakov, F. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e29988 · Cited by 12
The effect of Ba Duan Jin exercise intervention on cardiovascular disease: a meta-analysis of randomized controlled trials
Chen, J., Zhang, M., Wang, Y., Zhang, Z., Gao, S., & Zhang, Y. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1425843 · Cited by 14
Environmental chemical exposures and a machine learning-based model for predicting hypertension in NHANES 2003–2016
Guo, K., Ni, W., Du, L., Zhou, Y., Cheng, L., & Zhou, H. (2024) · BMC Cardiovascular Disorders · doi:10.1186/s12872-024-04216-z · Cited by 13
Evaluation of blood pressure control and associated factors among patients with hypertension in Iraq: a prospective cross-sectional study
Nassr, O. A., & Forsyth, P. (2019) · Journal of Pharmacy And Bioallied Sciences · doi:10.4103/jpbs.jpbs_82_19 · Cited by 11
Application of supercritical fluid chromatography for separation and quantitation of 15 co‐formulated binary anti‐hypertensive medications using a single elution protocol
Pandya, P. A., Shah, P. A., & Shrivastav, P. S. (2020) · Biomedical Chromatography · doi:10.1002/bmc.5035 · Cited by 11
Chronic Limb Remote Ischemic Conditioning may have an Antihypertensive Effect in Patients with Hypertension
Guo, W., Ren, C., Zhang, B., Zhao, W., Gao, Y., Yu, W., & Ji, X. (2021) · Aging and Disease · doi:10.14336/ad.2021.0604 · Cited by 11
Characterizing CD38 Expression and Enzymatic Activity in the Brain of Spontaneously Hypertensive Stroke-Prone Rats
Hannawi, Y., Ewees, M. G., Moore, J. T., & Zweier, J. L. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.881708 · Cited by 11
Effect of Dietary Fiber (Oat Bran) Supplement in Heart Rate Lowering in Patients with Hypertension: A Randomized DASH-Diet-Controlled Clinical Trial
Ju, Y., Zhang, C., Zhang, Z., Zhu, H., Liu, Y., Liu, T., Ojo, O., Qiu, J., & Wang, X. (2022) · Nutrients · doi:10.3390/nu14153148 · Cited by 14
Brain and cardiovascular-related changes are associated with aging, hypertension, and atrial fibrillation
Rim, D., Henderson, L. A., & Macefield, V. G. (2022) · Clinical Autonomic Research · doi:10.1007/s10286-022-00907-9 · Cited by 12
Circulating miR-29b decrease in response to sarcopenia in patients with cardiovascular risk factors in older Chinese
He, N., Zhang, Y., Zhang, Y., Feng, B., Zheng, Z., & Ye, H. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.1094388 · Cited by 11
The association between daily total physical activity and risk of cardiovascular disease among hypertensive patients: a 10-year prospective cohort study in China
Zhou, T., Su, J., Tao, R., Qin, Y., Zhou, J., Lu, Y., Hua, Y., Jin, J., Guo, Y., Chen, Z., et al. (2021) · BMC Public Health · doi:10.1186/s12889-021-10551-z · Cited by 11
Glutathione-related antioxidant defense system in patients with hypertensive retinopathy
Pavlovschi, E., Pantea, V., Borovic, D., & Tagadiuc, O. (2021) · Romanian Journal of Ophthalmology · doi:10.22336/rjo.2021.9 · Cited by 11
Moderate Physical Exercise Activates ATR2 Receptors, Improving Inflammation and Oxidative Stress in the Duodenum of 2K1C Hypertensive Rats
da Silva, A. C. A., Severo, J. S., dos Santos, B. L. B., Mendes, P. H. M., Nobre, L. M. S., de Oliveira, A. P., Ferreira, F. C. S., Medeiros, J. V. R., Lima‐Júnior, R. C. P., Havt, A., et al. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.734038 · Cited by 11
Cardiovascular implications in adolescent and young adult hypertension
Raina, R., Khooblall, A., Shah, R., Vijayvargiya, N., Khooblall, P., Sharma, B., Datla, N., Narang, A., Yerigeri, K., Melachuri, M. K., et al. (2022) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2305166 · Cited by 14
A new immune disease: systemic hypertension
Copur, S., Peltek, İ. B., Mutlu, A., Tanrıöver, C., & Kanbay, M. (2023) · Clinical Kidney Journal · doi:10.1093/ckj/sfad059 · Cited by 11
Changes in cardiac-driven perivascular fluid movement around the MCA in a pharmacological model of acute hypertension detected with non-invasive MRI
Evans, P., Sajic, M., Yu, Y., Harrison, I. F., Hosford, P. S., Smith, K. J., Lythgoe, M. F., Stuckey, D. J., & Wells, J. A. (2023) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x231209641 · Cited by 10
Unveiling the therapeutic potential of corn silk against hypertension: A critical review
Goyal, D., Jyoti, A., Kaur, M., Dhir, S., Rasane, P., Gunjal, M., Kaur, S., Ullah, R., Erċışlı, S., Choudhary, R., et al. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105020 · Cited by 10
Antihypertensive mechanism of the medicine food homology compound solution with high ACE inhibition rate based on network pharmacology and molecular docking
Xu, M., Ren, R., Zhang, Z., Li, X., Liu, L., Liu, H., Yu, X., & Masumuzzaman, M. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105077 · Cited by 10
Sleep timing and the prevalence of hypertension in middle-aged and older populations: the sleep heart health study
Zhao, S., Zhao, J., Wei, S., Wang, W., Wu, Y., & Yan, B. (2024) · BMC Psychiatry · doi:10.1186/s12888-024-06174-4 · Cited by 9
Etiopathogenesis of kidney disease in minority populations and an updated special focus on treatment in diabetes and hypertension
Umeukeje, E. M., Washington, J. T., & Nicholas, S. B. (2022) · Journal of the National Medical Association · doi:10.1016/j.jnma.2022.05.004 · Cited by 10
Biochemical Analysis of Urine Samples from Diabetic and Hypertensive Patients without Renal Dysfunction Using Spectrophotometry and Raman Spectroscopy Techniques Aiming Classification and Diagnosis
Vieira, E. E. D. S., Silveira, L., Carvalho, H. C., Bispo, J. A. M., Fernandes, F. B., & Fernandes, A. B. (2022) · Bioengineering · doi:10.3390/bioengineering9100500 · Cited by 10
Association between AGTR1 (c.1166 A>C) Polymorphisms and Kidney Injury in Hypertension.
Zeng, Y.-Y., Jiang, Y.-F., Huang, Z.-Y., Li, K., & Zhou, Y.-F. (2023) · Frontiers in Bioscience · doi:10.31083/j.fbl2807146 · Cited by 9
Ameliorative effect of mussel-derived ACE inhibitory peptides on spontaneous hypertension rats
You, Q., Sun, X., Chen, J., Yu, J., & Wei, Y. (2023) · European Journal of Nutrition · doi:10.1007/s00394-023-03222-9 · Cited by 10
Protective effects of kefir in the angiotensin II-dependent hypertension
Monteiro, B. L., Dias, A. T., Wanderkoke, S. D. C., Yokota, R., Casarini, D. E., Leal, M. A. S., Nogueira, B. V., Meyrelles, S. S., Campos‐Toimil, M., Campagnaro, B. P., et al. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104260 · Cited by 10
Sex Differences in Cumulative Exposure to Metabolic Risk Factors Before Hypertension Onset: The Cohort of the Tehran Lipid and Glucose Study
Ramezankhani, A., Azizi, F., Momenan, A. A., & Hadaegh, F. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.121.021922 · Cited by 10
Purinoceptor: a novel target for hypertension
Li, X., Zhu, L., Lv, J., & Cao, X. (2022) · Purinergic Signalling · doi:10.1007/s11302-022-09852-8 · Cited by 11
Adrenomedullin Improves Cardiac Remodeling and Function in Obese Rats with Hypertension
Qian, P., Wang, Q., Wang, F., Dai, H., Wang, H., Gao, Q., Zhou, Y., & Zhou, Y. (2022) · Pharmaceuticals · doi:10.3390/ph15060719 · Cited by 10
ROS Suppression by Egg White Hydrolysate in DOCA-Salt Rats—An Alternative Tool against Vascular Dysfunction in Severe Hypertension
Abreu, E. D. L., Moro, C. R., Kanaan, S. H. H., de Paula, R. B., Herrera, C. T., Costa, P. H. D., Peçanha, F. M., Vassallo, D. V., Rossoni, L. V., Miguel, M., et al. (2022) · Antioxidants · doi:10.3390/antiox11091713 · Cited by 10
Foot reflexology for reduction of blood pressure in hypertensive individual: A systematic review
Vijayakumar, V., Chidambaram, Y., Boopalan, D., Akila, A., Poonguzhali, S., Poornima, R., & Kuppusamy, M. (2023) · The Foot · doi:10.1016/j.foot.2023.101974 · Cited by 10
A Reappraisal of the Effects of L-type Ca2+ Channel Blockers on Store-Operated Ca2+ Entry and Heart Failure
Bird, G. S. J., D’Agostin, D. M., Alsanosi, S., Lip, S. Z. L., Padmanabhan, S., & Parekh, A. B. (2023) · Function · doi:10.1093/function/zqad047 · Cited by 10
A comprehensive review of phytochemistry, pharmacology and clinical applications of Uncariae Ramulus Cum Uncis
Zhang, Z., Li, Y., Wu, G., Li, Y., Zhang, D., & Wang, R. (2023) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2023.104638 · Cited by 9
Antibacterial and Angiotensin I-Converting Enzyme (ACE) Inhibition Activities of Essential Oil from Java Cardamom (Amomum compactum) Fruit
Darsih, C., Windarsih, A., Damayanti, E., Amiru, V. A., Indrianingsih, A. W., Marfuah, S., & Sujarwo, W. (2023) · Indian Journal of Microbiology · doi:10.1007/s12088-023-01080-x · Cited by 9
Acute Effects of Coffee Consumption on Blood Pressure and Endothelial Function in Individuals with Hypertension on Antihypertensive Drug Treatment: A Randomized Crossover Trial
de Castro, F. B. D. A. L., Castro, F. G., Cunha, M. R., Pacheco, S., Freitas‐Silva, O., Neves, M. F., & Klein, M. R. S. T. (2024) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-024-00622-8 · Cited by 10

Authors: Oparil, S., Acelajado, M. C., Bakris, G. L., Berlowitz, D. R., Cífková, R., Dominiczak, A. F., Grassi, G., Jordan, J., Poulter, N. R., Rodgers, A., & Whelton, P. K.
Affiliations: University of Alabama at Birmingham (US)
University of Chicago (US)
Boston University (US)
Charles University (CZ)
University of Glasgow (GB)
MultiMedica (IT)
University of Cologne (DE)
Imperial College London (GB)
The George Institute for Global Health (AU)
Tulane University (US)
Corresponding author: Oparil, Suzanne
ORCID: Oparil, Suzanne
Acelajado, Maria Czarina
Bakris, George L.
Berlowitz, Dan R.
Cífková, Renata
Dominiczak, Anna F.
Grassi, Guido
Jordan, Jens
Poulter, Neil R.
Rodgers, Anthony
Whelton, Paul K.
Venue: Nature Reviews Disease Primers
Publisher: Springer Science and Business Media LLC
Published: 2018-03-22
Volume: 4
Issue: 1
Pages: 18014-18014
ISSN: 2056-676X (ISSN-L)
DOI: 10.1038/nrdp.2018.14
PMC: PMC6477925
OpenAlex: W4211019091
Cited by: 1,167
References: 215
Citations by year: 2026: 142 · 2025: 182 · 2024: 177 · 2023: 193 · 2022: 195 · 2021: 158 · 2020: 71 · 2019: 34 · 2018: 14
FWCI: 12.91
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.springernature.com/gp/researchers/text-and-data-mining (tdm)
www.springernature.com/gp/researchers/text-and-data-mining (vor)
Locations: Nature Reviews Disease Primers (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
elib (German Aerospace Center) (acceptedVersion)
ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (acceptedVersion, cc-by-sa)
UNSWorks (University of New South Wales, Sydney, Australia) (submittedVersion, cc-by-nc-nd)
BOA (University of Milano-Bicocca) (submittedVersion)
Spiral (Imperial College London) (submittedVersion)
Funders: Pfizer
AstraZeneca
Sanofi
Arbor Pharmaceuticals
Novo Nordisk
Servier
H. Lundbeck A/S
National Institute of General Medical Sciences (P20GM109036)
National Institute of Diabetes and Digestive and Kidney Diseases (U01DK060963)
NIH Clinical Center
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
Keywords: systemic arterial hypertension, cardiovascular disease, hypertension risk factors, atherosclerotic cardiovascular disease risk, target organ damage, lifestyle modification, antihypertensive drugs, ACE inhibitors, angiotensin receptor blockers, calcium channel blockers, thiazide diuretics, genetic susceptibility
MeSH terms: Antihypertensive Agents, Calcium Channel Blockers, Cardiovascular Diseases, Diuretics, Humans, Hypertension, Quality of Life, Renin-Angiotensin System, Sympathetic Nervous System

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Hypertension.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks