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Harnessing the power of RADseq for ecological and evolutionary genomics

Open access
Andrews, Kimberly R., Good, Jeffrey M., Miller, Michael R., Luikart, Gordon, Hohenlohe, Paul A.·2016·Nature Reviews Genetics

Abstract

High-throughput techniques based on restriction site-associated DNA sequencing (RADseq) are enabling the low-cost discovery and genotyping of thousands of genetic markers for any species, including non-model organisms, which is revolutionizing ecological, evolutionary and conservation genetics. Technical differences among these methods lead to important considerations for all steps of genomics studies, from the specific scientific questions that can be addressed, and the costs of library preparation and sequencing, to the types of bias and error inherent in the resulting data. In this Review, we provide a comprehensive discussion of RADseq methods to aid researchers in choosing among the many different approaches and avoiding erroneous scientific conclusions from RADseq data, a problem that has plagued other genetic marker types in the past.

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Metadata

Authors
Andrews, K. R., Good, J. M., Miller, M. R., Luikart, G., & Hohenlohe, P. A.
Venue
Nature Reviews Genetics
Published
2016-01-05
Volume
17
Issue
2
Pages
81-92
ISSN
  • 1471-0056 (ISSN-L)
  • 1471-0064
OpenAlex
W2263977295
Cited by
1,489
References
6
FWCI
21.83
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Harnessing the power of RADseq for ecological and evolutionary genomics. https://app.cochat.ai/papers/10.1038/nrg.2015.28
The paper
Andrews, K. R., Good, J. M., Miller, M. R., Luikart, G., & Hohenlohe, P. A. (2016). Harnessing the power of RADseq for ecological and evolutionary genomics. Nature Reviews Genetics. https://doi.org/10.1038/nrg.2015.28

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