Cited by 401Genomics and Phylogenetic StudiesGenetic diversity and population structureEnvironmental DNA in Biodiversity Studies

How genomics can help biodiversity conservation

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Theissinger, Kathrin, Fernandes, Carlos, Formenti, Giulio, Bista, Iliana, Berg, Paul R., Bleidorn, Christoph, Bombarely, Aureliano, Crottini, Angelica +125 more·2023·Trends in Genetics

Abstract

The availability of public genomic resources can greatly assist biodiversity assessment, conservation, and restoration efforts by providing evidence for scientifically informed management decisions. Here we survey the main approaches and applications in biodiversity and conservation genomics, considering practical factors, such as cost, time, prerequisite skills, and current shortcomings of applications. Most approaches perform best in combination with reference genomes from the target species or closely related species. We review case studies to illustrate how reference genomes can facilitate biodiversity research and conservation across the tree of life. We conclude that the time is ripe to view reference genomes as fundamental resources and to integrate their use as a best practice in conservation genomics.

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Authors
Theissinger, K., Fernandes, C., Formenti, G., Bista, I., Berg, P. R., Bleidorn, C., Bombarely, A., Crottini, A., Gallo, G. R., Godoy, J. A., Jentoft, S., Malukiewicz, J., Mouton, A., Oomen, R. A., Paez, S., Palsbøll, P. J., Pampoulie, C., Ruiz-López, M. J., Secomandi, S., Svardal, H., Theofanopoulou, C., de Vries, J., Waldvogel, A.-M., Zhang, G., Jarvis, E. D., Bálint, M., Ciofi, C., Waterhouse, R. M., Mazzoni, C. J., Höglund, J., Aghayan, S. A., Alioto, T. S., Almudi, I., Alvarez, N., Alves, P. C., Amorim do Rosario, I. R., Antunes, A., Arribas, P., Baldrian, P., Bertorelle, G., Böhne, A., Bonisoli-Alquati, A., Boštjančić, L. L., Boussau, B., Breton, C. M., Buzan, E., Campos, P. F., Carreras, C., Castro, L. F. C., Chueca, L. J., Čiampor, F., Conti, E., Cook-Deegan, R., Croll, D., Cunha, M. V., Delsuc, F., Dennis, A. B., Dimitrov, D., Faria, R., Favre, A., Fedrigo, O. D., Fernández, R., Ficetola, G. F., Flot, J.-F., Gabaldón, T., Agius, D. R., Giani, A. M., Gilbert, M. T. P., Grebenc, T., Guschanski, K., Guyot, R., Hausdorf, B., Hawlitschek, O., Heintzman, P. D., Heinze, B., Hiller, M., Husemann, M., Iannucci, A., Irisarri, I., Jakobsen, K. S., Klinga, P., Kloch, A., Kratochwil, C. F., Kusche, H., Layton, K. K. S., Leonard, J. A., Lerat, E., Liti, G., Manousaki, T., Marques-Bonet, T., Matos-Maraví, P., Matschiner, M., Maumus, F., Mc Cartney, A. M., Meiri, S., Melo-Ferreira, J., Mengual, X., Monaghan, M. T., Montagna, M., Mysłajek, R. W., Neiber, M. T., Nicolas, V., Novo, M., Ozretić, P., Palero, F., Pârvulescu, L., Pascual, M., Paulo, O. S., Pavlek, M., Pegueroles, C., Pellissier, L., Pesole, G., Primmer, C. R., Riesgo, A., Rüber, L., Rubolini, D., Salvi, D., Seehausen, O., Seidel, M., Studer, B., Theodoridis, S., Thines, M., Urban, L., Vasemägi, A., Vella, A., Vella, N., Vernes, S. C., Vernesi, C., Vieites, D. R., Wheat, C. W., Wörheide, G., Wurm, Y., & Zammit, G.
Affiliations
  • Senckenberg Biodiversity and Climate Research Centre (DE)
  • University of Lisbon (PT)
  • Rockefeller University (US)
  • Naturalis Biodiversity Center (NL)
  • University of Oslo (NO)
  • University of Göttingen (DE)
  • University of Milan (IT)
  • Universidade do Porto (PT)
  • Estación Biológica de Doñana (ES)
  • German Primate Center (DE)
  • University of Liège (BE)
  • University of Groningen (NL)
  • Marine and Freshwater Research Institute (IS)
  • University of Antwerp (BE)
  • City University of New York (US)
  • University of Cologne (DE)
  • University of Copenhagen (DK)
  • SIB Swiss Institute of Bioinformatics (CH)
  • Berlin Center for Genomics in Biodiversity Research (DE)
  • Uppsala University (SE)
  • Laboratoire de Biométrie et Biologie Evolutive (FR)
  • Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
Corresponding author
Höglund, Jacob
ORCID
Venue
Trends in Genetics
Publisher
Elsevier BV
Published
2023-07
Volume
39
Issue
7
Pages
545-559
ISSN
0168-9525 (ISSN-L)
OpenAlex
W4321019193
Cited by
401
References
150
Citations by year
2026: 117 · 2025: 132 · 2024: 120 · 2023: 32
FWCI
10.68
Type
journal article
Language
en
Open access
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  • ETH Zürich Research Collection
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Funders
Biotechnology and Biological Sciences Research Council (BB/T015683/1)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
  • Physical Sciences › Environmental Science › Ecology › Environmental DNA in Biodiversity Studies
Keywords
conservation genomics, biodiversity conservation, reference genome, biodiversity assessment, species restoration, genomic resources, tree of life
MeSH terms
Conservation of Natural Resources, Genome, Genomics, Biodiversity

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