The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Epistasis — the essential role of gene interactions in the structure and evolution of genetic systems
Open accessAbstract
Epistasis, or interactions between genes, has long been recognized as fundamentally important to understanding the structure and function of genetic pathways and the evolutionary dynamics of complex genetic systems. With the advent of high-throughput functional genomics and the emergence of systems approaches to biology, as well as a new-found ability to pursue the genetic basis of evolution down to specific molecular changes, there is a renewed appreciation both for the importance of studying gene interactions and for addressing these questions in a unified, quantitative manner.
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Citations
Cites
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Cited by
Meta-analysis of the heritability of human traits based on fifty years of twin studies
Polderman, T. J. C., Benyamin, B., de Leeuw, C. A., Sullivan, P. F., van Bochoven, A., Visscher, P. M., & Posthuma, D. (2015) · Nature Genetics · doi:10.1038/ng.3285 · Cited by 2,467
Detecting gene–gene interactions that underlie human diseases
Cordell, H. J. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2579 · Cited by 1,350
VanderWeele, T. J., & Knol, M. J. (2014) · Epidemiologic Methods · doi:10.1515/em-2013-0005 · Cited by 1,127
The genetic causes of convergent evolution
Stern, D. L. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3483 · Cited by 818
Empirical fitness landscapes and the predictability of evolution
de Visser, J. A. G. M., & Krug, J. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3744 · Cited by 715
Metadata
- Authors
- Phillips, P. C.
- Venue
- Nature Reviews Genetics
- Published
- 2008-11
- Volume
- 9
- Issue
- 11
- Pages
- 855-867
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W2094189284
- Cited by
- 1,575
- References
- 12
- FWCI
- 5.54
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
