XV.—The Correlation between Relatives on the Supposition of Mendelian Inheritance.
Abstract
Several attempts have already been made to interpret the well-established results of biometry in accordance with the Mendelian scheme of inheritance. It is here attempted to ascertain the biometrical properties of a population of a more general type than has hitherto been examined, inheritance in which follows this scheme. It is hoped that in this way it will be possible to make a more exact analysis of the causes of human variability. The great body of available statistics show us that the deviations of a human measurement from its mean follow very closely the Normal Law of Errors, and, therefore, that the variability may be uniformly measured by the standard deviation corresponding to the square root of the mean square error. When there are two independent causes of variability capable of producing in an otherwise uniform population distributions with standard deviations σ 1 and σ 2 , it is found that the distribution, when both causes act together, has a standard deviation . It is therefore desirable in analysing the causes of variability to deal with the square of the standard deviation as the measure of variability. We shall term this quantity the Variance of the normal population to which it refers, and we may now ascribe to the constituent causes fractions or percentages of the total variance which they together produce. It is desirable on the one hand that the elementary ideas at the basis of the calculus of correlations should be clearly understood, and easily expres…
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- Authors
- Fisher, R. A.
- Corresponding author
- Fisher, R. A.
- Venue
- Transactions of the Royal Society of Edinburgh
- Publisher
- Cambridge University Press (CUP)
- Published
- 1919
- Volume
- 52
- Issue
- 2
- Pages
- 399-433
- ISSN
- 0080-4568 (ISSN-L)
- 2053-5945
- OpenAlex
- W2303043072
- Cited by
- 4,387
- References
- 0
- Citations by year
- 2026: 107 · 2025: 147 · 2024: 145 · 2023: 157 · 2022: 177 · 2021: 225 · 2020: 210 · 2019: 200 · 2018: 160 · 2017: 147 · 2016: 143 · 2015: 151 · 2014: 169 · 2013: 153 · 2012: 165
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Transactions of the Royal Society of Edinburgh (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and phenotypic traits in livestock
- Keywords
- Mendelian inheritance, human variability, variance components, heritability, normal distribution, standard deviation, biometry
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