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Cited by 461

The DOI matches its Crossref record; 177 of the 177 references it cites were found in a registry or an index.

Genomic signatures of selection at linked sites: unifying the disparity among species

Open access
Cutter, Asher D., Payseur, Bret A.·2013·Nature Reviews Genetics

Abstract

Population genetics theory supplies powerful predictions about how natural selection interacts with genetic linkage to sculpt the genomic landscape of nucleotide polymorphism. Both the spread of beneficial mutations and the removal of deleterious mutations act to depress polymorphism levels, especially in low-recombination regions. However, empiricists have documented extreme disparities among species. Here we characterize the dominant features that could drive differences in linked selection among species — including roles for selective sweeps being 'hard' or 'soft' — and the concealing effects of demography and confounding genomic variables. We advocate targeted studies of closely related species to unify our understanding of how selection and linkage interact to shape genome evolution.

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Metadata

Authors
Cutter, A. D., & Payseur, B. A.
Venue
Nature Reviews Genetics
Published
2013-03-12
Volume
14
Issue
4
Pages
262-274
ISSN
  • 1471-0056 (ISSN-L)
  • 1471-0064
OpenAlex
W1978025281
Cited by
461
References
177
FWCI
4.56
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Genomic signatures of selection at linked sites: unifying the disparity among species. https://app.cochat.ai/papers/10.1038/nrg3425
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Cutter, A. D., & Payseur, B. A. (2013). Genomic signatures of selection at linked sites: unifying the disparity among species. Nature Reviews Genetics. https://doi.org/10.1038/nrg3425

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.