The art and design of genetic screens: Drosophila melanogaster

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Items 101–200 of 547

1. Drosophila melanogaster as a model system for human brain cancers
   Renee D Read · 2011 · Glia
2. Genome-wide manipulations of Drosophila melanogaster with transposons, Flp recombinase, and ΦC31 integrase.
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3. Decoding sORF translation – from small proteins to gene regulation
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4. Mitochondrial dynamics and mitophagy in Parkinson's disease: A fly point of view
   Sophia von Stockum, Alice Nardin, Emilie Schrepfer, Elena Ziviani · 2015 · Neurobiology of Disease
5. Connecting genotypes, phenotypes and fitness: harnessing the power of CRISPR /Cas9 genome editing
   Jeremy M. Bono, Eugenia C. Olesnicky, Luciano Matias Matzkin · 2015 · Molecular Ecology
6. Developmental genetics with model organisms
   U. Irion, C. Nüsslein-Volhard · 2022 · Proceedings of the National Academy of Sciences of the United States of America
7. TAPDANCE: An automated tool to identify and annotate transposon insertion CISs and associations between CISs from next generation sequence data
   A. Sarver, Jesse Erdman, T. Starr, D. Largaespada, K. Silverstein · 2012 · BMC Bioinformatics
8. Genome-wide RNAi as a route to gene function in Drosophila.
   David Kuttenkeuler, M. Boutros · 2004 · Briefings in Functional Genomics & Proteomics
9. A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy
   Matera, Ivana, Watkins-Chow, Dawn E., Loftus, Stacie K., Hou, Ling, Incao, Arturo, Silver, Debra L., Rivas, Cecelia, Elliott, Eugene C., Baxter, Laura L., Pavan, William J. · 2008 · Human Molecular Genetics
10. A Short History and Description of Drosophila melanogaster Classical Genetics: Chromosome Aberrations, Forward Genetic Screens, and the Nature of Mutations
    T. Kaufman · 2017 · Genetics
11. Analysis of the cell cycle in zebrafish embryos.
    J. Shepard, H. Stern, K. Pfaff, J. Amatruda · 2004 · Methods in Cell Biology
12. Escaping the mouse trap: the selection of new Evo-Devo model species.
    M. Milinkovitch, Athanasia C. Tzika · 2007 · Journal of Experimental Zoology Part B: Molecular and Developmental Evolution
13. A Genetic Screen for Attenuated Growth Identifies Genes Crucial for Intraerythrocytic Development of Plasmodium falciparum
    Bharath Balu, N. Singh, S. Maher, J. Adams · 2010 · PLoS ONE
14. Regulation of the Hippo pathway in cancer biology
    Sungho Moon, So Yeon Park, Hyun Woo Park · 2018 · Cellular and Molecular Life Sciences
15. Environmental chemical mediated male reproductive toxicity: Drosophila melanogaster as an alternate animal model.
    A. Tiwari, P. Pragya, K. R. Ram, D. Chowdhuri · 2011 · Theriogenology
16. The Q-System: A Versatile Expression System for Drosophila
    Olena Riabinina, Christopher J. Potter · 2016 · Methods in molecular biology
17. At the crossroads of polarity, proliferation and apoptosis: the use of Drosophila to unravel the multifaceted role of endocytosis in tumor suppression
    Thomas Vaccari, D. Bilder · 2009 · Molecular Oncology
18. Model Organisms in the Fight against Muscular Dystrophy: Lessons from Drosophila and Zebrafish
    Emilie Auxerre-Plantié, Marta Migocka-Patrzałek, Małgorzata Daczewska, Krzysztof Jagla · 2015 · Molecules
19. Drosophila Cancer Models Identify Functional Differences Between Ret Fusions
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20. Analysis of Cell Proliferation, Senescence and Cell Death in Zebrafish Embryos
    Daniel Verduzco, J. Amatruda · 2011 · Methods in Cell Biology
21. Sterile Inflammation in Drosophila
    Zeeshan Shaukat, Dawei Liu, Stephen L. Gregory · 2015 · Mediators of Inflammation
22. Drosophila melanogaster as a model system for genetics of postnatal cardiac function
    Matthew J. Wolf, H. Rockman · 2008 · Drug Discovery Today : Disease Models
23. Functional analysis of the allatostatin-A type gene in the cricket Gryllus bimaculatus and the armyworm Spodoptera frugiperda
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24. Drosophila melanogaster as a powerful tool for studying insect toxicology.
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25. Systematic screening of a Drosophila ORF library in vivo uncovers Wnt/Wg pathway components.
    C. Schertel, Da-Shun Huang, Mikael Björklund, J. Bischof, Dingzi Yin, Rong-Xia Li, Yi Wu, Rong Zeng, Jia-Rui Wu, J. Taipale et al. · 2013 · Developmental Cell
26. Embryonic expression patterns of the Drosophila dystrophin-associated glycoprotein complex orthologs.
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27. Drosophila melanogaster: Deciphering Alzheimer's Disease.
    F. H. Tan, Ghows Azzam · 2017 · Malaysian Journal of Medical Sciences
28. Fukushima's biological impacts: the case of the pale grass blue butterfly.
    Wataru Taira, Chiyo Nohara, Atsuki Hiyama, J. Otaki · 2014 · Journal of Heredity
29. A gene delivery system for human cells mediated by both a cell-penetrating peptide and a piggyBac transposase.
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30. A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila
    Li Wang, Z. Tu, Feng-Zhu Sun · 2009 · BMC Genomics
31. piggyBac is an effective tool for functional analysis of the Plasmodium falciparum genome
    Bharath Balu, C. Chauhan, S. Maher, Douglas A. Shoue, J. Kissinger, Malcolm J. Jr Fraser, J. Adams · 2009 · BMC Microbiology
32. Yeast, Flies, Worms, and Fish in the Study of Human Disease
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33. CPEB1, a novel gene silenced in gastric cancer: a Drosophila approach
    J. Caldeira, Joana Simões-Correia, J. Paredes, M. Pinto, S. Sousa, G. Corso, D. Marrelli, F. Roviello, Paulo Pereira, D. Weil et al. · 2011 · Gut
34. Genetic variants of <i>Adam17</i> differentially regulate TGFβ signaling to modify vascular pathology in mice and humans
    Kawasaki, Kyoko, Freimuth, Julia, Meyer, Dominique S., Lee, Marie M., Tochimoto-Okamoto, Akiko, Benzinou, Michael, Clermont, Frederic F., Wu, Gloria, Roy, Ritu, Letteboer, Tom G. W. et al. · 2014 · Proceedings of the National Academy of Sciences
35. Genome-wide transposon screening and quantitative insertion site sequencing for cancer gene discovery in mice
    Mathias J. Friedrich, Lena Rad, I. Bronner, Alexander J. Strong, Wei Wang, Julia Weber, M. Mayho, H. Ponstingl, Thomas Engleitner, C. Grove et al. · 2017 · Nature Protocols
36. Zebrafish Genetic Models for Arrhythmia
    D. Milan, C. Macrae · 2008 · Progress in Biophysics and Molecular Biology
37. Model systems in drug discovery: chemical genetics meets genomics
    Pamela M. Carroll, Brian Andrew Dougherty, Petra Ross‐Macdonald, Kailtin Browman, Kevin J. Fitzgerald · 2003 · Pharmacology & Therapeutics
38. Drosophila melanogaster as a versatile model organism to study genetic epilepsies: An overview
    Florian Fischer, R. Karge, Y. Weber, H. Koch, S. Wolking, Aaron Voigt · 2023 · Frontiers in Molecular Neuroscience
39. A method to measure myocardial calcium handling in adult Drosophila
    Na Lin, N. Badie, Lin Yu, Dennis M. Abraham, He-Ping Cheng, N. Bursac, H. Rockman, Matthew J. Wolf · 2011 · Circulation Research
40. RNAi phenotypes are influenced by the genetic background of the injected strain
    Peter Kitzmann, Jonas Schwirz, Christian Schmitt-Engel, Gregor Bucher · 2013 · BMC Genomics
41. EMS screens : from mutagenesis to screening and mapping.
    Christian Bökel · 2008 · Methods in molecular biology
42. The ancestral levels of transcription and the evolution of sexual phenotypes in filamentous fungi
    Frances Trail, Zheng Wang, Kayla Stefanko, Caitlyn Cubba, Jeffrey P. Townsend · 2017 · PLoS Genetics
43. Alzheimer's disease: the silver tsunami of the 21st century
    A. Sarkar, Madison N. Irwin, Aditi Singh, M. Riccetti, Ashutosh Kumar Singh · 2016 · Neural Regeneration Research
44. The zebrafish:scalable in vivo modeling for systems biology
    Rahul C. Deo, Calum A. MacRae · 2010 · WIREs Systems Biology and Medicine
45. Signaling and transcriptional control of pituitary development.
    Robert C. Burgess, V. Lunyak, M. Rosenfeld · 2002 · Current Opinion in Genetics and Development
46. What have we learned from Drosophila models of Parkinson’s disease?
    Ming Guo · 2010 · Progress in brain research
47. Murder on the Ovarian Express: A Tale of Non-Autonomous Cell Death in the Drosophila Ovary
    Diane Patricia Vig Lebo, Kimberly McCall · 2021 · Cells
48. Tracing neuronal circuits in transgenic animals by transneuronal control of transcription (TRACT)
    Ting-hao Huang, Peter J. Niesman, Deepshika Arasu, Donghyung Lee, A. L. De La Cruz, Antuca Callejas, Elizabeth J. Hong, C. Lois · 2017 · eLife
49. From fat fruitfly to human obesity
    Wanli W. Smith, Joseph M. Thomas, Jing-Nan Liu, Tianxia Li, T. Moran · 2014 · Physiology and Behavior
50. Drosophila NinaB and NinaD Act Outside of Retina to Produce Rhodopsin Chromophore
    Guie Gu, Jing Yang, Kathleen A. Mitchell, Joseph E. O’Tousa · 2004 · Journal of Biological Chemistry
51. Mechanisms of suppression: The wiring of genetic resilience
    Jolanda van Leeuwen, Carles Pons, Charles Boone, Brenda J. Andrews · 2017 · Bioessays
52. Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster
    Hangnoh Lee, Dong-Yeon Cho, Cale Whitworth, Robert C. Eisman, Melissa Phelps, John Roote, Thomas C. Kaufman, Kevin R Cook, Steven R. H. Russell, Teresa M. Przytycka et al. · 2016 · PLoS Genetics
53. Histamine Recycling Is Mediated by CarT, a Carcinine Transporter in Drosophila Photoreceptors
    Ying Xu, Futing An, J. Borycz, J. Borycz, I. Meinertzhagen, Tao Wang · 2015 · PLoS Genetics
54. Functional and genetic analysis of choroid plexus development in zebrafish
    Hannah E. Henson, Chaithanyarani Parupalli, Bensheng Ju, Michael R. Taylor · 2014 · Frontiers in Neuroscience
55. Anterior–Posterior Axis Specification in Drosophila Oocytes: Identification of Novel bicoid and oskar mRNA Localization Factors
    Chin-Wen Chang, Dmitry Nashchekin, Lucy Wheatley, Uwe Irion, Katja Dahlgaard, Tessa G. Montague, Jacqueline Hall, Daniel St Johnston · 2011 · Genetics
56. Genome-wide genetic screening with chemically mutagenized haploid embryonic stem cells
    Forment, Josep V, Herzog, Mareike, Coates, Julia, Konopka, Tomasz, Gapp, Bianca V, Nijman, Sebastian M, Adams, David J, Keane, Thomas M, Jackson, Stephen P · 2017 · Nature Chemical Biology
57. Development of the piggyBac transposable system for Plasmodium berghei and its application for random mutagenesis in malaria parasites
    Jannik Fonager, B. Franke-Fayard, J. Adams, J. Ramesar, Onny Klop, Shahid M. Khan, C. Janse, A. Waters · 2011 · BMC Genomics
58. Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises
    Luke McAlary, Yee Lian Chew, Jeremy Stephen Lum, Nicholas J. Geraghty, Justin J. Yerbury, Neil R. Cashman · 2020 · Frontiers in Cellular Neuroscience
59. Carbohydrate Metabolism in Drosophila: Reliance on the Disaccharide Trehalose
    Alejandro Reyes-DelaTorre, Ma. Teresa Peña-Rangel, J. Riesgo-Escovar · 2012 · InTech eBooks
60. Genetic modifiers interact with maternal determinants in vascular development of Tgfb1(-/-) mice.
    Yang Tang, M. McKinnon, L. Leong, Sarah Rusholme, Susana Wang, R. Akhurst · 2003 · Human Molecular Genetics
61. From genes to aging in Drosophila.
    S. Helfand, B. Rogina · 2003 · Advances in Genetics
62. “What You Need, Baby, I Got It”: Transposable Elements as Suppliers of Cis-Operating Sequences in Drosophila
    R. Moschetti, Antonio Palazzo, Patrizio Lorusso, L. Viggiano, René Massimiliano Marsano · 2020 · Biology
63. Inwardly Rectifying Potassium (Kir) Channels Represent a Critical Ion Conductance Pathway in the Nervous Systems of Insects
    Ruilu Chen, D. R. Swale · 2018 · Scientific Reports
64. Next generation mothers: Maternal control of germline development in zebrafish
    R. Dosch · 2015 · Critical reviews in biochemistry and molecular biology
65. Dorsal activity of maternal squint is mediated by a non-coding function of the RNA
    Shi-Min Lim, P. Kumari, Patrick C. Gilligan, H. Quach, S. Mathavan, Karuna Sampath · 2012 · Development
66. A Genome-Wide Enhancer Screen Implicates Sphingolipid Composition in Vacuolar ATPase Function in Saccharomyces cerevisiae
    Gregory C. Finnigan, Margret Ryan, Tom H. Stevens · 2011 · Genetics
67. Moving forward with chemical mutagenesis in the mouse
    Timothy P. O'Brien, W. Frankel · 2004 · Journal of Physiology
68. Parallel Genetic and Proteomic Screens Identify Msps as a CLASP–Abl Pathway Interactor in Drosophila
    Laura Anne Lowery, Haeryung Lee, Cecilia S. Lu, R. Murphy, R. Obar, Bo Zhai, M. Schedl, D. Van Vactor, Y. Zhan · 2010 · Genetics
69. Next-generation large-scale binary protein interaction network for Drosophila melanogaster
    Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard C. Binari, Donghui Yang‐Zhou, Kenneth H. Wan, Joel S. Bader et al. · 2023 · Nature Communications
70. Genetics in Light of Transcriptional Adaptation
    Zacharias Kontarakis, Didier Y. R. Stainier · 2020 · Trends in Genetics
71. The Trojan Female Technique for pest control: a candidate mitochondrial mutation confers low male fertility across diverse nuclear backgrounds in Drosophila melanogaster
    D. Dowling, D. Tompkins, N. Gemmell · 2015 · Evolutionary Applications
72. Microbial model communities: To understand complexity, harness the power of simplicity
    J. Bengtsson-Palme · 2020 · Computational and Structural Biotechnology Journal
73. Mammalian Models of Traumatic Brain Injury and a Place for Drosophila in TBI Research
    Ekta J. Shah, Katherine Gurdziel, Douglas Mark Ruden · 2019 · Frontiers in Neuroscience
74. RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens
    N. Temiz, B. Moriarity, Natalie K. Wolf, Jesse D. Riordan, A. Dupuy, D. Largaespada, A. Sarver · 2016 · Genome Research
75. Strategies for gene disruption in Drosophila
    Shih-Ching Lin, Yu-Yun Chang, Chih-Chiang Chan · 2014 · Cell & Bioscience
76. RUNX family members are covalently modified and regulated by PIAS1-mediated sumoylation
    J.-H. Kim, J-W Jang, Y.-S. Lee, J. Lee, Xin-Zi Chi, Y. Li, M.-K. Kim, D-M Kim, B.-S. Choi, Jiyeon Kim et al. · 2014 · Oncogenesis
77. Lessons From Sleeping Flies: Insights fromDrosophila melanogasteron the Neuronal Circuitry and Importance of Sleep
    Sheetal Potdar, Vasu Sheeba · 2013 · Journal of Neurogenetics
78. Identification of JAK/STAT pathway regulators—Insights from RNAi screens
    Patrick Müller, M. Boutros, M. Zeidler · 2008 · Seminars in Cell and Developmental Biology
79. Adipokine and fat body in flies: connecting organs.
    Eleonora Meschi, R. Delanoue · 2021 · Molecular and Cellular Endocrinology
80. Neuromuscular degeneration and locomotor deficit in a Drosophila model of mucopolysaccharidosis VII is attenuated by treatment with resveratrol
    Sudipta Bar, Mohit Prasad, Rupak Datta · 2018 · Disease Models & Mechanisms
81. Combining molecular docking and 3-D pharmacophore generation to enclose the in vivo antigenotoxic activity of naturally occurring aromatic compounds: myricetin, quercetin, rutin, and rosmarinic acid.
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82. What can flies tell us about copper homeostasis?
    Adam G. Southon, Richard Burke, James Camakaris · 2013 · Metallomics
83. A molecular model for sporadic human aneuploidy.
    W. D. Warren, Kylie L. Gorringe · 2006 · Trends in Genetics
84. A Guide to Genome-Wide In Vivo RNAi Applications in Drosophila.
    Aynur Kaya-Çopur, F. Schnorrer · 2016 · Methods in molecular biology
85. Unraveling Novel Mechanisms of Neurodegeneration Through a Large-Scale Forward Genetic Screen in Drosophila
    Samantha L. Deal, Shinya Yamamoto · 2019 · Frontiers in Genetics
86. Role of inward rectifier potassium channels in salivary gland function and sugar feeding of the fruit fly, Drosophila melanogaster.
    D. R. Swale, Zhi-Lin Li, F. Guerrero, Adalberto A. Pérez de León, L. Foil · 2017 · Pesticide Biochemistry and Physiology
87. System-dependent regulations of colour-pattern development: a mutagenesis study of the pale grass blue butterfly
    Masaki Iwata, Atsuki Hiyama, Joji M. Otaki · 2013 · Scientific Reports
88. Functional genomics of Plasmodium falciparum through transposon‐mediated mutagenesis
    Bharath Balu, J. Adams · 2006 · Cellular Microbiology
89. A Comparative Perspective on Wnt/β-Catenin Signalling in Cell Fate Determination
    Clare L. Garcin, Shukry James Habib · 2017 · Results and problems in cell differentiation
90. Searching for synergy in silico, in vitro and in vivo
    Nikolaus J. Sucher · 2014 · Synergy
91. Modifiers and mechanisms of multi-system polyglutamine neurodegenerative disorders: lessons from fly models
    Moushami Mallik, S. C. Lakhotia · 2010 · Journal of Genetics
92. Partial loss of GATA factor Pannier impairs adult heart function in Drosophila.
    Li Qian, R. Bodmer · 2009 · Human Molecular Genetics
93. 'Fly-ing' from rare to common neurodegenerative disease mechanisms
    Mengqi Ma, Matthew J. Moulton, Shenzhao Lu, Hugo Jozef Bellen · 2022 · Trends in Genetics
94. From gene to treatment: supporting rare disease translational research through model systems
    J. Hmeljak, M. Justice · 2019 · Disease Models & Mechanisms
95. Tet protein function during Drosophila development
    Fei Wang, S. Minakhina, Hiep Tran, Neha Changela, Joseph J Kramer, R. Steward · 2018 · PLoS ONE
96. Toward a complete Drosophila deficiency kit
    J. Roote, S. Russell · 2012 · Genome Biology
97. MicroRNA Transgene Overexpression Complements Deficiency-Based Modifier Screens in Drosophila
    S. Szuplewski, J. Kugler, Sing-Fee Lim, Pushpa Verma, Ya-Wen Chen, S. Cohen · 2012 · Genetics
98. Integrating Computational Biology and Forward Genetics in Drosophila
    Stein Aerts, Sven Vilain, Shu Hu, L. Tranchevent, Roland Barriot, Jie-Kun Yan, Yves Moreau, Bassem A. Hassan, Xiao-Jiang Quan · 2009 · PLoS Genetics
99. The emerging field of chemical genetics: potential applications for pesticide discovery.
    Terence A. Walsh · 2007 · Pest Management Science
100. Conserved family of glycerol kinase loci in Drosophila melanogaster.
     Julian A. Martinez Agosto, E. Mccabe · 2006 · Molecular Genetics and Metabolism