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Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
Open accessAbstract
Cholangiocarcinomas are a heterogeneous group of bile duct cancers and the second most common primary liver tumour worldwide. In this Consensus statement, the newly formed European Network for the Study of Cholangiocarcinoma (ENS-CCA) detail the classification, pathophysiology and underlying mechanisms, and current therapies for cholangiocarcinoma, as well as future perspectives. Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies with features of biliary tract differentiation. CCA is the second most common primary liver tumour and the incidence is increasing worldwide. CCA has high mortality owing to its aggressiveness, late diagnosis and refractory nature. In May 2015, the “European Network for the Study of Cholangiocarcinoma” (ENS-CCA: www.enscca.org or www.cholangiocarcinoma.eu ) was created to promote and boost international research collaboration on the study of CCA at basic, translational and clinical level. In this Consensus Statement, we aim to provide valuable information on classifications, pathological features, risk factors, cells of origin, genetic and epigenetic modifications and current therapies available for this cancer. Moreover, future directions on basic and clinical investigations and plans for the ENS-CCA are highlighted.
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Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma
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Metadata
- Authors
- Banales, J. M., Cardinale, V., Carpino, G., Marzioni, M., Andersen, J. B., Invernizzi, P., Lind, G. E., Folseraas, T., Forbes, S. J., Fouassier, L., Geier, A., Calvisi, D. F., Mertens, J. C., Trauner, M., Benedetti, A., Maroni, L., Vaquero, J., Macias, R. I. R., Raggi, C., Perugorria, M. J., Gaudio, E., Boberg, K. M., Marin, J. J. G., & Alvaro, D.
- Venue
- Nature Reviews Gastroenterology & Hepatology
- Published
- 2016-04-20
- Volume
- 13
- Issue
- 5
- Pages
- 261-280
- ISSN
- 1759-5045 (ISSN-L)
- 1759-5053
- OpenAlex
- W2337387091
- Cited by
- 1,376
- References
- 10
- FWCI
- 21.08
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Banales, J. M., Cardinale, V., Carpino, G., Marzioni, M., Andersen, J. B., Invernizzi, P., Lind, G. E., Folseraas, T., Forbes, S. J., Fouassier, L., Geier, A., Calvisi, D. F., Mertens, J. C., Trauner, M., Benedetti, A., Maroni, L., Vaquero, J., Macias, R. I. R., Raggi, C., . . . Alvaro, D. (2016). Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA). Nature Reviews Gastroenterology & Hepatology. https://doi.org/10.1038/nrgastro.2016.51
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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