Evolving functions of endothelial cells in inflammation

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Furchgott, R. F., & Zawadzki, J. V. (1980) · Nature · doi:10.1038/288373a0 · Cited by 12,064

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

Micheau, O., & Tschopp, J. (2003) · Cell · doi:10.1016/s0092-8674(03)00521-x · Cited by 2,738

The immune response in atherosclerosis: a double-edged sword

Hansson, G. K., & Libby, P. (2006) · Nature reviews. Immunology · doi:10.1038/nri1882 · Cited by 2,220

Phenotypic Heterogeneity of the Endothelium

Aird, W. C. (2007) · Circulation Research · doi:10.1161/01.res.0000255691.76142.4a · Cited by 1,824

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

Caterina, R. D., Libby, P., Peng, H., Thannickal, V. J., Rajavashisth, T. B., Gimbrone, M. A., Shin, W. S., & Liao, J. K. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118074 · Cited by 1,781

Vascular Permeability Factor/Vascular Endothelial Growth Factor: A Critical Cytokine in Tumor Angiogenesis and a Potential Target for Diagnosis and Therapy

Dvorak, H. F. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.2002.10.088 · Cited by 1,600

Endothelial Cell-to-Cell Junctions: Molecular Organization and Role in Vascular Homeostasis

Bazzoni, G., & Dejana, E. (2004) · Physiological Reviews · doi:10.1152/physrev.00035.2003 · Cited by 1,384

Angiopoietin-1 protects the adult vasculature against plasma leakage

Thurston, G., Rudge, J. S., Ioffe, E., Zhou, H., Ross, L. H., Croll, S. D., Glazer, N. L., Holash, J. A., McDonald, D. M., & Yancopoulos, G. D. (2000) · Nature Medicine · doi:10.1038/74725 · Cited by 1,314

Phenotypic Heterogeneity of the Endothelium

Aird, W. C. (2007) · Circulation Research · doi:10.1161/01.res.0000255690.03436.ae · Cited by 1,288

Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis

Shibuya, M., & Claesson, L. (2005) · Experimental Cell Research · doi:10.1016/j.yexcr.2005.11.012 · Cited by 1,083

Blocking Mast Cell–Mediated Type I Hypersensitivity in Experimental Allergic Conjunctivitis by Monocyte Chemoattractant Protein-1/CCR2

Tominaga, T., Miyazaki, D., Sasaki, S.-I., Mihara, S., Komatsu, N., Yakura, K., & Inoue, Y. (2009) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.09-3637 · Cited by 26

Retinal dendritic cell recruitment, but not function, was inhibited in MyD88 and TRIF deficient mice

Heuss, N. D., Pierson, M. J., Montaniel, K. R. C., McPherson, S. W., Lehmann, U., Hussong, S. A., Ferrington, D. A., Low, W. C., & Gregerson, D. S. (2014) · Journal of Neuroinflammation · doi:10.1186/s12974-014-0143-1 · Cited by 26

Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1

Boily-Larouche, G., Iscache, A., Zijenah, L., Humphrey, J., Mouland, A., Ward, B., & Roger, M. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007211 · Cited by 32

Biological efficacy of a 600 mg loading dose of clopidogrel in ST-elevation myocardial infarction

Berbis, J., Laine, M., Arméro, S., Bessereau, J., Jacquin, L., Bonello, C., Camillieri, E., Barragan, P. T., Dignat‐George, F., Paganelli, F. F., et al. (2012) · Thrombosis and Haemostasis · doi:10.1160/th12-02-0125 · Cited by 25

Pharmacological Activation of Nrf2 by Rosolic Acid Attenuates Endoplasmic Reticulum Stress in Endothelial Cells

Amin, K. N., Rajagru, P., Sarkar, K., Munuswamy‐Ramanujam, G., Suzuki, T., Ali, D., & Ramkumar, K. M. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/2732435 · Cited by 25

Endothelial Dysfunction and SARS-CoV-2 Infection: Association and Therapeutic Strategies

Deng, H., Tang, T.-X., Chen, D., Tang, L., Yang, X., & Tang, Z. (2021) · Pathogens · doi:10.3390/pathogens10050582 · Cited by 26

Inflammatory activation of endothelial cells increases glycolysis and oxygen consumption despite inhibiting cell proliferation

Wik, J. A., Phung, D., Kolan, S. S., Haraldsen, G., Skålhegg, B. S., & Fosse, J. H. (2021) · FEBS Open Bio · doi:10.1002/2211-5463.13174 · Cited by 25

Danlou Tablets Inhibit Atherosclerosis in Apolipoprotein E-Deficient Mice by Inducing Macrophage Autophagy: The Role of the PI3K-Akt-mTOR Pathway

Liu, C., Chen, G., Chen, Y., Dang, Y., Nie, G., Wu, D., Li, J., Chen, Z., Yang, H., He, D., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.724670 · Cited by 25

Mucosal immunization with an adenoviral vector vaccine confers superior protection against RSV compared to natural immunity

Maier, C., Fuchs, J., Irrgang, P., Wißing, M. H., Beyerlein, J., Tenbusch, M., & Lapuente, D. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.920256 · Cited by 25

COVID-19 and the potential of Janus family kinase (JAK) pathway inhibition: A novel treatment strategy

Khaledi, M., Sameni, F., Yahyazade, S., Radandish, M., Owlia, P., Bagheri, N., Afkhami, H., Mahjoor, M., Esmaelpour, Z., Kohansal, M., et al. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.961027 · Cited by 25

Early vascular endothelial complications after hematopoietic cell transplantation: Role of the endotheliopathy in biomarkers and target therapies development

Moreno‐Castaño, A. B., Salas, M. Q., Palomo, M., Martínez-Sánchez, J., Rovira, M., Fernández‐Avilés, F., Martı́nez, C., Cid, J., Castro, P., Escolar, G., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1050994 · Cited by 30

Endothelial Autophagy Dysregulation in Diabetes

Salemkour, Y., & Lenoir, O. (2023) · Cells · doi:10.3390/cells12060947 · Cited by 28

Synthesizing a multifunctional polymer to construct the catalytically NO-generating coating for improving corrosion resistance and biocompatibility of the magnesium alloy stent materials

Chen, J., Liu, X., Hong, Q., Meng, L., Ji, Y., Wang, L., Zhang, Q., Lin, J., & Pan, C. (2023) · Progress in Organic Coatings · doi:10.1016/j.porgcoat.2023.108058 · Cited by 25

Dengue Virus‐Induced Inflammation of the Endothelium and the Potential Roles of Sphingosine Kinase‐1 and MicroRNAs

Aloia, A. L., Abraham, A. M., Bonder, C. S., Pitson, S. M., & Carr, J. M. (2015) · Mediators of Inflammation · doi:10.1155/2015/509306 · Cited by 25

Safflor yellow B suppresses angiotensin II-mediated human umbilical vein cell injury via regulation of Bcl-2/p22phox expression

Wang, C., He, Y., Yang, M., Sun, H., Zhang, S., & Wang, C. (2013) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2013.08.018 · Cited by 25

Endothelial cell tolerance to lipopolysaccharide challenge is induced by monophosphoryl lipid A

Stark, R. J., Choi, H., Koch, S. R., Fensterheim, B. A., Lamb, F. S., & Sherwood, E. R. (2015) · Clinical Science · doi:10.1042/cs20150592 · Cited by 25

The Role of Angiogenesis in the Pathogenesis of Psoriasis: Mechanisms and Clinical Implications

Guérard, S. (2014) · Journal of Clinical & Experimental Dermatology Research · doi:10.4172/2155-9554.s2-007 · Cited by 25

An interaction between BRG1 and histone modifying enzymes mediates lipopolysaccharide‐induced proinflammatory cytokines in vascular endothelial cells

Zhang, Y., Yuan, Y., Li, Z., Chen, H., Fang, M., Xiao, P., & Xu, Y. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28595 · Cited by 25

Heterogeneity of chemical composition of lipid droplets in endothelial inflammation and apoptosis

Pacia, M. Z., Sternak, M., Mateuszuk, Ł., Stojak, M., Kaczor, A., & Chłopicki, S. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2020.118681 · Cited by 25

Inflammation-Driven Nanohitchhiker Enhances Postoperative Immunotherapy by Alleviating Prostaglandin E2-Mediated Immunosuppression

Liu, Y., He, J., Li, M., Ren, K., & Zhao, Z. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c17357 · Cited by 24

MiR-34a regulates blood–tumor barrier function by targeting protein kinase Cε

Zhao, W., Wang, P., Ma, J., Liu, Y., Li, Z., Li, Z., Wang, Z., Chen, L., & Xue, Y. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e14-10-1474 · Cited by 24

The Emerging Role of COX-2, 15-LOX and PPARγ in Metabolic Diseases and Cancer: An Introduction to Novel Multi-target Directed Ligands (MTDLs)

Alaaeddine, R. A., Elzahhar, P. A., AlZaim, I., Abou-Kheir, W. G., Belal, A. S. F., & EL‐Yazbi, A. F. (2020) · Current Medicinal Chemistry · doi:10.2174/0929867327999200820173853 · Cited by 26

Renin-angiotensin system blocker and outcomes of COVID-19: a systematic review and meta-analysis

Lee, H. W., Yoon, C., Jang, E. J., & Lee, C. (2021) · Thorax · doi:10.1136/thoraxjnl-2020-215322 · Cited by 24

Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death

Zhang, L., Zou, L., Jiang, X., Cheng, S., Zhang, J., Qin, X., Qin, Z., Chen, C., & Zou, Z. (2021) · Nanotoxicology · doi:10.1080/17435390.2021.1919330 · Cited by 24

Angiocrine Regulation of Epithelial Barrier Integrity in Inflammatory Bowel Disease

Stürzl, M., Kunz, M., Krug, S. M., & Naschberger, E. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.643607 · Cited by 26

Relationship Between Endothelial and Angiogenesis Biomarkers Envisage Mortality in a Prospective Cohort of COVID-19 Patients Requiring Respiratory Support

Maldonado, F., Morales, D., Díaz-Papapietro, C., Valdés, C., Fernández, C., Valls, N., Lazo, M. T., Espinoza, C., González, R., Gutiérrez, R., et al. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.826218 · Cited by 24

Bioactive Based Nanocarriers for the Treatment of Viral Infections and SARS-CoV-2

Goyal, R., Bala, R., Sindhu, R. K., Zehravi, M., Madaan, R., Ramproshad, S., Mondal, B., Dey, A., Rahman, M. H., & Cavalu, S. D. (2022) · Nanomaterials · doi:10.3390/nano12091530 · Cited by 24

The Role of Dexmedetomidine in Tumor-Progressive Factors in the Perioperative Period and Cancer Recurrence: A Narrative Review

Cai, Q., Liu, G., Huang, L., Guan, Y., Wei, H., Dou, Z., Liu, D., Hu, Y., & Gao, M. (2022) · Drug Design Development and Therapy · doi:10.2147/dddt.s358042 · Cited by 24

T cell interaction with activated endothelial cells primes for tissue-residency

Wienke, J., Veldkamp, S. R., Struijf, E. M., Yengej, F. A. Y., van der Wal, M., van Royen‐Kerkhof, A., & van Wijk, F. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.827786 · Cited by 25

Therapeutic targeting of angiopoietins in tumor angiogenesis and cancer development

Thapa, K., Khan, H., Kaur, G., Kumar, P., & Singh, T. G. (2023) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2023.149130 · Cited by 27

Endothelial activation and damage as a common pathological substrate in different pathologies and cell therapy complications

Palomo, M., Moreno‐Castaño, A. B., Salas, M. Q., Escribano-Serrat, S., Rovira, M., Guillén, E., Fernandez, S., Ventosa-Capell, H., Youssef, L., Crispi, F., et al. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1285898 · Cited by 28

Genes Influenced by the Non-Muscle Isoform of Myosin Light Chain Kinase Impact Human Cancer Prognosis

Zhou, T., Wang, T., & Garcia, J. G. N. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094325 · Cited by 24

Taming endothelial activation with a microRNA

Fish, J. E., & Cybulsky, M. I. (2012) · Journal of Clinical Investigation · doi:10.1172/jci63818 · Cited by 24

VCAM-1 specific PEGylated SAINT-based lipoplexes deliver siRNA to activated endothelium in vivo but do not attenuate target gene expression

Leus, N. G. J., Morselt, H. W. M., Zwiers, P. J., Kowalski, P. S., Ruiters, M. H. J., Molema, G., & Kamps, J. A. A. M. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2014.04.041 · Cited by 24

Loss of Estrogen-Related Receptor Alpha Facilitates Angiogenesis in Endothelial Cells

Likhite, N., Yadav, V., Milliman, E. J., Sopariwala, D. H., Lorca, S., Narayana, N. P., Sheth, M., Reineke, E. L., Giguère, V., & Narkar, V. A. (2019) · Molecular and Cellular Biology · doi:10.1128/mcb.00411-18 · Cited by 24

Myeloid-Derived Suppressor Cells Are Involved in Lysosomal Acid Lipase Deficiency–Induced Endothelial Cell Dysfunctions

Zhao, T., Ding, X., Du, H., & Yan, C. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1301941 · Cited by 24

Total saponins from Albizia julibrissin inhibit vascular endothelial growth factor-mediated angiogenesis in vitro and in vivo

Cai, W., Li, Y., Yi, Q., Xie, F., Du, B., Feng, L., & Qiu, L. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.3228 · Cited by 24

Fractalkine (CX3CL1), GM‐CSF and VEGF‐a levels are reduced by statins in adult patients

Cimato, T. R., & Palka, B. (2014) · Clinical and Translational Medicine · doi:10.1186/2001-1326-3-14 · Cited by 22

Secreted immunoregulatory proteins in the skin

Nöske, K. (2017) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2017.10.008 · Cited by 23

Relation between Monocyte to High-Density Lipoprotein Cholesterol Ratio and Presence and Severity of Erectile Dysfunction

Kadihasanoglu, M., Karabay, E., Yucetas, U., Erkan, E., & Ozbek, E. (2018) · Aktuelle Urologie · doi:10.1055/s-0042-123163 · Cited by 23

Angio-3, a 10-residue peptide derived from human plasminogen kringle 3, suppresses tumor growth in mice via impeding both angiogenesis and vascular permeability

Venugopal, S., Kao, C., Chandna, R., Sulochana, K. N., Vivekanandan, S., Chen, M., Kini, R. M., & Ge, R. (2018) · Angiogenesis · doi:10.1007/s10456-018-9616-7 · Cited by 23

IAP inhibitor, Embelin increases VCAM-1 levels on the endothelium, producing lymphocytic infiltration and antitumor immunity

Nakajima, K., Ino, Y., Yamazaki–Itoh, R., Naito, C., Shimasaki, M., Takahashi, M., Esaki, M., Nara, S., Kishi, Y., Shimada, K., et al. (2020) · OncoImmunology · doi:10.1080/2162402x.2020.1838812 · Cited by 24

Understanding the Role of Blood Vessels in the Neurologic Manifestations of Coronavirus Disease 2019 (COVID-19)

Whitmore, H. A. B., & Kim, L. A. (2021) · American Journal Of Pathology · doi:10.1016/j.ajpath.2021.04.017 · Cited by 23

Immunometabolic bases of type 2 diabetes in the severity of COVID-19

Viurcos-Sanabria, R., & Escobedo, G. (2021) · World Journal of Diabetes · doi:10.4239/wjd.v12.i7.1026 · Cited by 24

Megakaryocyte Diversity in Ontogeny, Functions and Cell-Cell Interactions

Khatib-Massalha, E., & Méndez‐Ferrer, S. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.840044 · Cited by 26

The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Ameliorates Endothelial Inflammation and Microvascular Thrombosis in a Sepsis Mouse Model

Wang, S., Wang, X., Liu, C.-T., Chou, R., Chen, Z., Huang, P.-H., & Lin, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063065 · Cited by 23

Nectins and Nectin-like molecules drive vascular development and barrier function

Hermans, D., Rodriguez-Mogeda, C., Kemps, H., Bronckaers, A., de Vries, H. E., & Broux, B. (2023) · Angiogenesis · doi:10.1007/s10456-023-09871-y · Cited by 23

The Inflammatory Response to Double Stranded DNA in Endothelial Cells Is Mediated by NFκB and TNFα

Patel, S. J., Jindal, R., King, K. R., Tilles, A. W., & Yarmush, M. L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019910 · Cited by 23

Mast Cells and Ionizing Radiation Induce a Synergistic Expression of Inflammatory Genes in Endothelial Cells by a Mechanism Involving p38α MAP Kinase and (p65) NF-κB Activation

Blirando, K., Hneino, M., Martelly, I., Benderitter, M., Milliat, F., & François, A. (2012) · Radiation Research · doi:10.1667/rr3058.1 · Cited by 23

Integrin αDβ2 (CD11d/CD18) mediates experimental malaria-associated acute respiratory distress syndrome (MA-ARDS)

de Azevedo-Quintanilha, I. G., Vieira‐de‐Abreu, A., Ferreira, A. C., Nascimento, D. O., Siqueira, A. M., Campbell, R. A., Ferreira, T. P. T., Gutierrez, T. M., Ribeiro, G., Silva, P., et al. (2016) · Malaria Journal · doi:10.1186/s12936-016-1447-7 · Cited by 23

IP3 receptor signaling and endothelial barrier function

Sun, M., Geyer, M., & Komarova, Y. A. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2624-8 · Cited by 25

Integrated proteomic analysis of tumor necrosis factor α and interleukin 1β-induced endothelial inflammation

Béguin, E. P., van den Eshof, B. L., Hoogendijk, A. J., Nota, B., Mertens, K., Meijer, A. B., & van den Biggelaar, M. (2018) · Journal of Proteomics · doi:10.1016/j.jprot.2018.08.011 · Cited by 24

Endothelial NADPH Oxidase 4 Protects Against Angiotensin II-Induced Cardiac Fibrosis and Inflammation

Wang, M., Murdoch, C. E., Brewer, A. C., Ívetic, A., Evans, P. C., Shah, A. M., & Zhang, M. (2021) · ESC Heart Failure · doi:10.1002/ehf2.13228 · Cited by 23

Endothelial cells (ECs) for vascular tissue engineering: venous ECs are less thrombogenic than arterial ECs

Geenen, I. L., Molin, D. G. M., van den Akker, N. M. S., Jeukens, F., Spronk, H. M. H., Schurink, G. W. H., & Post, M. J. (2012) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.1642 · Cited by 23

The FOX transcription factors regulate vascular pathology diabetes and Tregs

Yang, X. F. (2009) · Frontiers in Bioscience-Scholar · doi:10.2741/s35 · Cited by 22

The blocking of uPAR suppresses lipopolysaccharide‐induced inflammatory osteoclastogenesis and the resultant bone loss through attenuation of integrin β3/Akt pathway

Kanno, Y., Ishisaki, A., Miyashita, M., & Matsuo, O. (2016) · Immunity, Inflammation and Disease · doi:10.1002/iid3.116 · Cited by 22

The endothelial glycocalyx—All the same? No, it is not

Suzuki, K., Miura, T., & Okada, H. (2023) · Acute Medicine & Surgery · doi:10.1002/ams2.896 · Cited by 22

Collagen concentration regulates neutrophil extravasation and migration in response to infection in an endothelium dependent manner

Calo, C. J., Patil, T., Palizzi, M. J., Wheeler, N., & Hind, L. E. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1405364 · Cited by 22

The proteomic landscape of in vitro cultured endothelial cells across vascular beds

Groten, S. A., Smit, E. R., van den Biggelaar, M., & Hoogendijk, A. J. (2024) · Communications Biology · doi:10.1038/s42003-024-06649-w · Cited by 22

Effects of Controlled Cortical Impact on the Mouse Brain Vasculome

Guo, S., Lok, J. M., Zhao, S., Leung, W., Som, A. T., Hayakawa, K., Wang, Q., Xing, C., Wang, X., Ji, X., et al. (2015) · Journal of Neurotrauma · doi:10.1089/neu.2015.4101 · Cited by 22

Cytoprotective pathways in the vascular endothelium. Do they represent a viable therapeutic target?

Mason, J. C. (2016) · Vascular Pharmacology · doi:10.1016/j.vph.2016.08.002 · Cited by 22

Clinical Characterization and Possible Pathological Mechanism of Acute Myocardial Injury in COVID-19

Li, S., Wang, J., Yan, Y., Zhang, Z., Gong, W., & Nie, S. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.862571 · Cited by 22

Endothelial Damage in Sepsis: The Importance of Systems Biology

Fernández‐Sarmiento, J., Schlapbach, L. J., Acevedo, L., Santana, C. R., Acosta‐Ampudia, Y., Diana, A., Monsalve, M., & Carcillo, J. A. (2022) · Frontiers in Pediatrics · doi:10.3389/fped.2022.828968 · Cited by 22

Human endothelial cells display a rapid tensional stress increase in response to tumor necrosis factor-α

Brandt, M., Gerke, V., & Betz, T. (2022) · PLoS ONE · doi:10.1371/journal.pone.0270197 · Cited by 21

Platelet-derived microRNA-223 attenuates TNF-α induced monocytes adhesion to arterial endothelium by targeting ICAM-1 in Kawasaki disease

Guo, M., Fan, S., Chen, Q., Jia, C., Qiu, M., Bu, Y., Tang, W. H., & Zhang, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.922868 · Cited by 22

Intestinal Injury Biomarkers Predict Mortality in Pediatric Severe Malaria

Sarangam, M. L., Namazzi, R., Datta, D., Bond, C., Vanderpool, C. P. B., Opoka, R. O., John, C. C., & Conroy, A. L. (2022) · mBio · doi:10.1128/mbio.01325-22 · Cited by 24

Transcriptomic profiling reveals sex-specific molecular signatures of adipose endothelial cells under obesogenic conditions

Rudnicki, M., Pislaru, A., Rezvan, O., Rullman, E., Fawzy, A., Nwadozi, E., Roudier, E. A., Gustafsson, T. P., & Haas, T. L. (2022) · iScience · doi:10.1016/j.isci.2022.105811 · Cited by 25

Inflammatory Activity of Epithelial Stem Cell Variants from Cystic Fibrosis Lungs Is Not Resolved by CFTR Modulators

Wang, S., Niroula, S., Hoffman, A., Khorrami, M., Khorrami, M., Yuan, F., Gasser, G. N., Choi, S. H., Liu, B., Li, J., et al. (2023) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202305-0818oc · Cited by 22

Endothelial dysfunction in neurodegenerative disease: Is endothelial inflammation an overlooked druggable target?

Ritson, M., Wheeler-Jones, C. P. D., & Stolp, H. B. (2024) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2024.578363 · Cited by 23

Chemical allergens stimulate human epidermal keratinocytes to produce lymphangiogenic vascular endothelial growth factor

Bae, O., Ahn, S.-Y., Jin, S. H., Hong, S. H., Lee, J., Kim, E. S., Jeong, T. C., Chun, Y., Lee, A., & Noh, M. (2015) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2015.01.008 · Cited by 22

Targeting the intragraft microenvironment and the development of chronic allograft rejection

Dormond, O., Dufour, M., Seto, T., Bruneau, S., & Briscoe, D. M. (2012) · Human Immunology · doi:10.1016/j.humimm.2012.07.334 · Cited by 22

Introduction: T Cell Trafficking in Inflammation and Immunity

Chimen, M., Apta, B. H. R., & McGettrick, H. M. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6931-9_6 · Cited by 22

EphA2 stimulates VCAM-1 expression through calcium-dependent NFAT1 activity

Funk, S. D., Finney, A. C., Yurdagul, A., Pattillo, C. B., & Orr, A. W. (2018) · Cellular Signalling · doi:10.1016/j.cellsig.2018.05.008 · Cited by 22

Acute effects of systemic inflammation upon the neuro-glial-vascular unit and cerebrovascular function

Brezzo, G., Simpson, J. E., Ameen‐Ali, K. E., Berwick, J., & Martin, C. J. (2020) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2020.100074 · Cited by 26

Nanotoxoids: Biomimetic Nanoparticle Vaccines against Infections

Guo, Z., Kubiatowicz, L. J., Fang, R. H., & Zhang, L. (2021) · Advanced Therapeutics · doi:10.1002/adtp.202100072 · Cited by 22

SREBP2 regulates the endothelial response to cytokines via direct transcriptional activation of KLF6

Fowler, J. W., Boutagy, N. E., Zhang, R., Horikami, D., Whalen, M., Romanoski, C. E., & Sessa, W. C. (2023) · Journal of Lipid Research · doi:10.1016/j.jlr.2023.100411 · Cited by 21

Regulation of inflammatory diseases via the control of mRNA decay

Yoshinaga, M., & Takeuchi, O. (2024) · Inflammation and Regeneration · doi:10.1186/s41232-024-00326-5 · Cited by 22

STING inhibitors and degraders: Potential therapeutic agents in inflammatory diseases

Wu, K., Xu, Y., Liu, P., Chen, K., & Zhao, Y. (2025) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2025.117632 · Cited by 25

Effects of substrate mechanics on angiogenic capacity and nitric oxide release in human endothelial cells

Jannatbabaei, A., Tafazzoli‐Shadpour, M., & Seyedjafari, E. (2020) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.14326 · Cited by 21

Gab2 (Grb2-Associated Binder2) Plays a Crucial Role in Inflammatory Signaling and Endothelial Dysfunction

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Carter, N. M., Mathiesen, A. H., Miller, N., Brown, M., Biancatelli, R. M. L. C., Catravas, J. D., & Dobrian, A. D. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.923081 · Cited by 21

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Albert, C., Bracaglia, L. G., Koide, A., DiRito, J. R., Lysyy, T., Harkins, L., Edwards, C. M., Richfield, O., Grundler, J., Zhou, K., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-33490-8 · Cited by 21

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Tanito, K., Nii, T., Yokoyama, Y., Oishi, H., Shibata, M., Hijii, S., Kaneko, R., Tateishi, C., Ito, S., Kishimura, A., et al. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.04.010 · Cited by 21

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Wang, D., Su, L., Poelstra, K. A., Grainger, D. W., van der Mei, H. C., Shi, L., & Busscher, H. J. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122576 · Cited by 22

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Tsolmongyn, B., Koide, N., Jambalganiin, U., Odkhuu, E., Naiki, Y., Komatsu, T., Yoshida, T., & Yokochi, T. (2013) · Immunology · doi:10.1111/imm.12147 · Cited by 21

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Gutierrez, L. S. (2008) · Biomarker Insights · doi:10.4137/bmi.s630 · Cited by 21

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Lee, Y. H., & Song, G. G. (2017) · Rheumatology International · doi:10.1007/s00296-017-3735-0 · Cited by 21

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Le, A. V., Hatachi, G., Beloiartsev, A., Ghaedi, M., Engler, A. J., Baevova, P., Niklason, L. E., & Calle, E. A. (2017) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.6b00784 · Cited by 21

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Wan, C., Xu, M., Huang, S., Wu, Q., Yuan, Y., Deng, W., & Tang, Q. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.8266 · Cited by 21

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Langholm, L. L., Rønnow, S. R., Sand, J. M. B., Leeming, D. J., Tal‐Singer, R., Miller, B. E., Vestbo, J., Karsdal, M. A., & Manon‐Jensen, T. (2020) · International Journal of COPD · doi:10.2147/copd.s235673 · Cited by 21

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Iqbal, K., Pierce, S. H., Kozai, K., Dhakal, P., Scott, R. L., Roby, K. F., Vyhlidal, C. A., & Soares, M. J. (2021) · Environmental Health Perspectives · doi:10.1289/ehp9256 · Cited by 20

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Turgeon, N. A., Kirk, A. D., & Iwakoshi, N. N. (2008) · Transplantation Reviews · doi:10.1016/j.trre.2008.08.001 · Cited by 21

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Butler, R., Bradford, D. R., & Rodgers, K. E. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.1006089 · Cited by 24

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Thomas, K., Rossaint, J., Ludwig, N., Mersmann, S., Kötting, N. M., Grenzheuser, J. C., Schemmelmann, L., Oguama, M., Margraf, A., Block, H., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-60174-w · Cited by 20

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Mo, J., Chen, Z., Xu, J., Wang, A., Dai, L., Cheng, A., Meng, X., Li, H., Wang, Y., on behalf of the CHANCE Investigators, et al. (2019) · Stroke · doi:10.1161/strokeaha.119.026845 · Cited by 20

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Lima, M. N., Freitas, R. J. R. X., Passos, B. A. B. R., Darze, A. M. G., Castro-Faria-Neto, H. C., & Maron‐Gutierrez, T. (2021) · NeuroImmunoModulation · doi:10.1159/000515557 · Cited by 19

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Adams, J. A., Uryash, A., & Lopez, J. R. (2022) · Biomedicines · doi:10.3390/biomedicines10123050 · Cited by 21

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Zenger, B., Rizzi, S. A., Steinberg, B. A., Ranjan, R., & Bunch, T. J. (2023) · Arrhythmia & Electrophysiology Review · doi:10.15420/aer.2022.29 · Cited by 21

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Al-Soudi, A., Kaaij, M. H., & Tas, S. W. (2017) · Autoimmunity Reviews · doi:10.1016/j.autrev.2017.07.008 · Cited by 162

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Pober, J. S., & Sessa, W. C. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a016345 · Cited by 317

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Ait‐Oufella, H., Mallat, Z., & Tedgui, A. (2011) · Springer eBooks · doi:10.1007/978-3-7091-0338-8_10 · Cited by 2