NLRs at the intersection of cell death and immunity

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Items 101–200 of 371

1. The inflammatory bowel disease (IBD) susceptibility genes NOD1 and NOD2 have conserved anti-bacterial roles in zebrafish
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2. Inflammasome-independent Role of Apoptosis-associated Speck-like Protein Containing a CARD (ASC) in T Cell Priming Is Critical for Collagen-induced Arthritis
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3. Specific Arabidopsis HSP90.2 alleles recapitulate RAR1 cochaperone function in plant NB-LRR disease resistance protein regulation
   David A. Hubert, Yijian He, Brian C. McNulty, Pablo Tornero, Jeffery L. Dangl · 2009 · Proceedings of the National Academy of Sciences
4. Highly diversified innate receptor systems and new forms of animal immunity
   Messier-Solek, Cynthia, Buckley, Katherine M., Rast, Jonathan P. · 2010 · Seminars in Immunology
5. Chemical probing reveals insights into the signaling mechanism of inflammasome activation
   Yi‐Nan Gong, Xiaoming Wang, Jiayi Wang, Zhenxiao Yang, Shan Li, Jieling Yang, Liping Liu, Xiaoguang Lei, Feng Shao · 2010 · Cell Research
6. A Yersinia Effector with Enhanced Inhibitory Activity on the NF-κB Pathway Activates the NLRP3/ASC/Caspase-1 Inflammasome in Macrophages
   Ying Zheng, Sarit Lilo, Igor E. Brodsky, Yue Zhang, Ruslan M. Medzhitov, Kenneth B. Marcu, James B. Bliska · 2011 · PLoS Pathogens
7. Chemokines Associated with Pathologic Responses to Orthopedic Implant Debris
   Nadim James Hallab, Joshua James Jacobs · 2017 · Frontiers in Endocrinology
8. Comparative analysis of barley leaf proteome as affected by drought stress
   Ahmed Ashoub, Tobias Beckhaus, Thomas Berberich, Michael Karas, Wolfgang Brüggemann · 2012 · Planta
9. Innate immunity to adenovirus: lessons from mice
   Atasheva, Svetlana, Yao, Jia, Shayakhmetov, Dmitry M. · 2019 · FEBS Letters
10. Protease propeptide structures, mechanisms of activation, and functions
    Lise Boon, Estefanía Ugarte-Berzal, Jennifer Vandooren, Ghislain Opdenakker · 2020 · Critical Reviews in Biochemistry and Molecular Biology
11. Mechanism of Bcl-2 and Bcl-X L inhibition of NLRP1 inflammasome: Loop domain-dependent suppression of ATP binding and oligomerization
    Benjamin Faustin, Ya Chen, Dayong Zhai, Gaëlle Le Negrate, Lydia Lartigue, Arnold C. Satterthwait, John C. Reed · 2009 · Proceedings of the National Academy of Sciences
12. Two-state selection of conformation-specific antibodies
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13. Genomic Clustering and Homology between HET-S and the NWD2 STAND Protein in Various Fungal Genomes
    Asen Daskalov, Mathieu Paoletti, Frédérique Ness, Sven J. Saupe · 2012 · PLoS ONE
14. Analysis of the ZAR1 Immune Complex Reveals Determinants for Immunity and Molecular Interactions
    Maël Baudin, Jana A. Hassan, Karl J. Schreiber, Jennifer D. Lewis · 2017 · PLANT PHYSIOLOGY
15. Renal macrophages and NLRP3 inflammasomes in kidney diseases and therapeutics
    Mohammad Islamuddin, Xue-Bin Qin · 2024 · Cell Death Discovery
16. CEACAM1 Negatively Regulates IL-1β Production in LPS Activated Neutrophils by Recruiting SHP-1 to a SYK-TLR4-CEACAM1 Complex
    Rongze Olivia. Lu, Hao Pan, John E. Shively · 2012 · PLoS Pathogens
17. NLRC5: a newly discovered MHC class I transactivator (CITA)
    Torsten B Meissner, Amy Li, Koichi S. Kobayashi · 2011 · Microbes and Infection
18. Current insights into the genetics of food allergy
    Kanika Kanchan, Selene M. Clay, Haritz Irizar, Supinda Bunyavanich, Rasika A. Mathias · 2021 · Journal of Allergy and Clinical Immunology
19. Modulation of Immune System by Kaposi’s Sarcoma-Associated Herpesvirus: Lessons from Viral Evasion Strategies
    Hye-Ra Lee, Kevin Brulois, LaiYee Wong, Jae Ung Jung · 2012 · Frontiers in Microbiology
20. Proceedings of the International Scientific and Practical Conference
    2023
21. Influenza A Virus NS1 Protein Inhibits the NLRP3 Inflammasome
    Woo-Chang Cheong, Hye-Ri Kang, Hyunyee Yoon, Suk‐Jo Kang, Jenny P.‐Y. Ting, Moon Jung Song · 2015 · PLoS ONE
22. The Transcription Factor IRF3 Triggers “Defensive Suicide” Necrosis in Response to Viral and Bacterial Pathogens
    Nelson Cesar Di Paolo, Konstantin Doronin, Lisa K. Baldwin, Thalia Papayannopoulou, Dmitry M. Shayakhmetov · 2013 · Cell Reports
23. Downregulation of IL-10 secretion by Treg cells in osteoarthritis is associated with a reduction in Tim-3 expression
    Shufeng Li, Jinliang Wan, William H. Anderson, Huaqiang Sun, Hu Zhang, Xianbo Peng, Zhaolong Yu, Teng Wang, Xinfeng Yan, Wendy Smith · 2016 · Biomedicine & Pharmacotherapy
24. Orthopedic Applications
    Nadim James Hallab, Joshua James Jacobs · 2020 · Elsevier eBooks
25. Methods for the proteomic identification of protease substrates
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26. The Interferon Stimulator Mitochondrial Antiviral Signaling Protein Facilitates Cell Death by Disrupting the Mitochondrial Membrane Potential and by Activating Caspases
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27. The NLRP12 Pyrin Domain: Structure, Dynamics, and Functional Insights
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28. Pyroptosis is involved in the inhibitory effect of FL118 on growth and metastasis in colorectal cancer
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29. The nucleic acid‐sensing inflammasomes
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30. Anthrax Lethal Toxin Induced Lysosomal Membrane Permeabilization and Cytosolic Cathepsin Release Is Nlrp1b/Nalp1b-Dependent
    Kathleen M. Averette, Matthew R. Pratt, Yanan Yang, Sara Bassilian, Julian P. Whitelegge, Joseph A. Loo, Tom W. Muir, Kenneth A. Bradley · 2009 · PLoS ONE
31. DAMPs ramp up drug toxicity
    Jacquelyn J. Maher · 2009 · Journal of Clinical Investigation
32. Tumor suppressor death-associated protein kinase is required for full IL-1β production
    Ya-Ting Chuang, Yu‐Chuan Lin, Kuan‐Hung Lin, Ting-Fang Chou, Wen‐Chih Kuo, Kaiting Yang, Pei‐Rung Wu, Ruey‐Hwa Chen, Adi Kimchi, Ming‐Zong Lai · 2010 · Blood
33. Graft-versus-Host Disease Is Independent of Innate Signaling Pathways Triggered by Pathogens in Host Hematopoietic Cells
    Hongmei Li, Catherine C. Matte-Martone, Hung Sheng Tan, Srividhya Venkatesan, Jennifer Madison McNiff, Anthony Jake Demetris, Dhanpat Jain, Fadi G. Lakkis, David M. Rothstein, Warren D. Shlomchik · 2010 · The Journal of Immunology
34. Immunomodulatory Effects of dsRNA and Its Potential as Vaccine Adjuvant
    Bo Jin, Tao Sun, Xiaohong Yu, Chao-Qun Liu, Ying-Xiang Yang, Ping Lu, Shan-feng Fu, Qiu Hui-Bin, Anthony E. T. Yeo · 2010 · BioMed Research International
35. EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1–TUFM protein complex
    Y Lei, Benjamin Kansy, Jing Li, L Cong, Y Liu, Sumita Trivedi, H Wen, Jenny P.-Y. Ting, Hongjiao Ouyang, Robert Louis Ferris · 2016 · Oncogene
36. CBL-interacting protein kinase 6 negatively regulates immune response to Pseudomonas syringae in Arabidopsis
    Atish Sardar, Ashis Kumar Nandi, Debasis Chattopadhyay · 2017 · Journal of Experimental Botany
37. The primate autoimmune encephalomyelitis model; a bridge between mouse and man
    Bert A. ‘t Hart, Yvette van Kooyk, Jeroen J.G. Geurts, Bruno Gran · 2015 · Annals of Clinical and Translational Neurology
38. Effect of betaine on hepatic insulin resistance through FOXO1-induced NLRP3 inflammasome
    Dae Hyun Kim, Seong Min Kim, Bonggi Lee, Eun Kyeong Lee, Ki Wung Chung, Kyoung Mi Moon, Hye Jin An, Kyung Mok Kim, Byung Pal Yu, Hae Young Chung · 2017 · The Journal of Nutritional Biochemistry
39. Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responses
    Silvia Lucena Lage, Carina de Lima Buzzo, Eduardo P. Amaral, Kely Catarine Matteucci, Liliana M. Massis, Marcelo Yudi Icimoto, Adriana K. Carmona, Maria Regina D’Império Lima, Mauricio Martins Rodrigues, Luís Carlos de Souza Ferreira et al. · 2013 · Proceedings of the National Academy of Sciences
40. Recognition of Virus Infection and Innate Host Responses to Viral Gene Therapy Vectors
    Dmitry M. Shayakhmetov, Nelson Cesar Di Paolo, Karen Louise Mossman · 2010 · Molecular Therapy
41. The Sw-5 Gene Cluster: Tomato Breeding and Research Toward Orthotospovirus Disease Control
    A. S. de Oliveira, L. S. Boiteux, Richard Kormelink, Renato O. Resende · 2018 · Frontiers in Plant Science
42. Comparative Immune Systems in Animals
    Shaochun Yuan, Xin Tao, Shengfeng Huang, Shangwu Chen, Anlong Xu · 2013 · Annual Review of Animal Biosciences
43. A Duplicated ESAT-6 Region of ESX-5 Is Involved in Protein Export and Virulence of Mycobacteria
    Swati Shah, Joe R. Cannon, Catherine Fenselau, Volker Briken · 2015 · Infection and Immunity
44. Cobalt Alloy Implant Debris Induces Inflammation and Bone Loss Primarily through Danger Signaling, Not TLR4 Activation: Implications for DAMP-ening Implant Related Inflammation
    Lauryn Samelko, Stefan Landgraeber, Kyron McAllister, Joshua James Jacobs, Nadim James Hallab · 2016 · PLoS ONE
45. Innate immune signalling at intestinal mucosal surfaces: a fine line between host protection and destruction
    Elke Cario · 2008 · Current Opinion in Gastroenterology
46. A Novel Pathway for Inducible Nitric-oxide Synthase Activation through Inflammasomes
    Carina de Lima Buzzo, Julia Cortina Campopiano, Liliana M. Massis, Silvia Lucena Lage, Alexandra A. Cassado, Rafael Leme-Souza, Larissa D. Cunha, Momtchilo Russo, Dario S. Zamboni, Gustavo Pessini Amarante-Mendes et al. · 2010 · Journal of Biological Chemistry
47. Three-dimensional Structure of the NLRP7 Pyrin Domain
    Anderson S. Pinheiro, Martina Proell, Clarissa Eibl, Rebecca Page, Robert Schwarzenbacher, Wolfgang Peti · 2010 · Journal of Biological Chemistry
48. Review: Toll-like receptors and NOD-like receptors in pulmonary antibacterial immunity
    Balamayooran Theivanthiran, Gayathriy Balamayooran, Samithamby Jeyaseelan · 2010 · Innate Immunity
49. ALDH2 Overexpression Alleviates High Glucose-Induced Cardiotoxicity by Inhibiting NLRP3 Inflammasome Activation
    Ruiping Cao, Dian Fang, Jiahui Wang, Ying Yu, Hongwei Ye, Pinfang Kang, Zhenghong Li, Hongju Wang, Qin Feng Gao · 2019 · Journal of Diabetes Research
50. Respective roles of TLR, RIG-I and NLRP3 in influenza virus infection and immunity: impact on vaccine design
    Takeshi Ichinohe · 2010 · Expert Review of Vaccines
51. Modulation of TLR2, TLR4, TLR5, NOD1 and NOD2 receptor gene expressions and their downstream signaling molecules following thermal stress in the Indian major carp catla (Catla catla)
    Madhubanti Basu, Mahismita Paichha, Banikalyan Swain, Saswati S. Lenka, Samarpal Singh, Rina Chakrabarti, Mrinal Samanta · 2015 · 3 Biotech
52. β2-glycoprotein I and oxidative inflammation in early atherogenesis: A progression from innate to adaptive immunity?
    Eiji Matsuura, Luis R. Lopez, Yehuda Shoenfeld, Paul R. J. Ames · 2012 · Autoimmunity Reviews
53. Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens
    S. Normand, N. Waldschmitt, Andreas Neerincx, R. J. Martínez-Torres, C. Chauvin, A. Couturier-Maillard, O. Boulard, L. Cobret, Fawaz Awad, L. Huot et al. · 2018 · Nature Communications
54. Ankrd17 positively regulates RIG‐I ‐like receptor ( RLR )‐mediated immune signaling
    Yetao Wang, Xiaomei Tong, Gang Li, Junhui Li, Min Deng, Xin Ye · 2012 · European Journal of Immunology
55. Autophagy, cell death, and cytokines in K. pneumoniae infection: therapeutic perspectives
    Sha Wei, Tingting Xu, Yuxin Chen, Kai Zhou · 2022 · Emerging Microbes & Infections
56. NLRP10 enhancesShigella-induced pro-inflammatory responses
    Katja Lautz, Anna Damm, Maureen Menning, Julia Wenger, Alexander C. Adam, Paola Zigrino, Elisabeth Kremmer, Thomas A. Kufer · 2012 · Cellular Microbiology
57. Dendritic cell altered states: what role for calcium?
    Russell D. Salter, Simon C. Watkins · 2009 · Immunological Reviews
58. Involvement of TLR2 and TLR4 in cell responses to Rickettsia akari
    Marco Quevedo-Díaz, Chang Hwa Song, Yanbao Xiong, Haiyan Chen, Larry M. Wahl, Suzana Radulović, Andrei E. Medvedev · 2010 · Journal of Leukocyte Biology
59. Distinct cathepsins control necrotic cell death mediated by pyroptosis inducers and lysosome-destabilizing agents
    Brojatsch, Jürgen, Lima, Heriberto, Palliser, Deborah, Jacobson, Lee S, Muehlbauer, Stefan M, Furtado, Raquel, Goldman, David L, Lisanti, Michael P, Chandran, Kartik · 2015 · Cell Cycle
60. The NLRP3 inflammasome, a target for therapy in diverse disease states
    Graham P. Cook, Sinisa Savic, Miriam Wittmann, Michael McDermott · 2010 · European Journal of Immunology
61. Propionibacterium acnes activates caspase‐1 in human neutrophils
    Berolla Sahdo, Eva Särndahl, Fredrik Elgh, Bo Söderquist · 2012 · Apmis
62. The Nucleotide-binding Leucine-rich Repeat (NLR) Family Member NLRX1 Mediates Protection against Experimental Autoimmune Encephalomyelitis and Represses Macrophage/Microglia-induced Inflammation
    Timothy K. Eitas, Wei-Chun Chou, Haitao Wen, Denis Gris, Gregory R. Robbins, W. June Brickey, Yoshitaka Oyama, Jenny P.‐Y. Ting · 2013 · Journal of Biological Chemistry
63. Association ofNLRP1genetic variants and mRNA overexpression with generalized vitiligo and disease activity in a Gujarat population
    Mitesh Dwivedi, Naresh C. Laddha, Mohmmad Shoab Mansuri, YogeshS Marfatia, Rasheedunnisa Begum · 2013 · British Journal of Dermatology
64. Mycobacterium tuberculosis Infection of Dendritic Cells Leads to Partially Caspase-1/11-Independent IL-1β and IL-18 Secretion but Not to Pyroptosis
    Hana Abdalla, Lalitha Srinivasan, Swati Shah, Katrin D. Mayer-Barber, Alan Sher, Fayyaz Shiraz Sutterwala, Volker Briken · 2012 · PLoS ONE
65. Clubroot in Brassica: recent advances in genomics, breeding, and disease management
    Jakir Hasan, Swati Megha, Habibur Rahman · 2021 · Genome
66. Molecular Drivers of Developmental Arrest in the Human Preimplantation Embryo: A Systematic Review and Critical Analysis Leading to Mapping Future Research
    Konstantinos Sfakianoudis, Evangelos Maziotis, Eleni Karantzali, Georgia Kokkini, Sokratis Grigoriadis, Amelia Pantou, Polina Giannelou, Konstantina Petroutsou, Christina Markomichali, Maria Fakiridou et al. · 2021 · International Journal of Molecular Sciences
67. YopJ-Induced Caspase-1 Activation in Yersinia-Infected Macrophages: Independent of Apoptosis, Linked to Necrosis, Dispensable for Innate Host Defense
    Ying Zheng, Sarit Lilo, Patricio Mena, James B. Bliska · 2012 · PLoS ONE
68. Understanding diversity of human innate immunity receptors: analysis of surface features of leucine-rich repeat domains in NLRs and TLRs
    Andrei Y. Istomin, Adam Godzik · 2009 · BMC Immunology
69. IL-1α and Complement Cooperate in Triggering Local Neutrophilic Inflammation in Response to Adenovirus and Eliminating Virus-Containing Cells
    Nelson Cesar Di Paolo, Lisa K. Baldwin, Eric Edward Irons, Thalia Papayannopoulou, Stephen Tomlinson, Dmitry M. Shayakhmetov · 2014 · PLoS Pathogens
70. Optimizing efficacy of mucosal vaccines
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71. Gut Microbiota, Inflammatory Bowel Disease, and Cancer: The Role of Guardians of Innate Immunity
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72. NBS-LRR Protein Pik-H4 Interacts with OsBIHD1 to Balance Rice Blast Resistance and Growth by Coordinating Ethylene-Brassinosteroid Pathway
    Hao Liu, Shuangyu Dong, Fengwei Gu, Wei Liu, Guili Yang, Ming Huang, Wuming Xiao, Yongzhu Liu, Tao Guo, Hui Wang et al. · 2017 · Frontiers in Plant Science
73. The Tandem CARDs of NOD2: Intramolecular Interactions and Recognition of RIP2
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74. NLRP2 controls age-associated maternal fertility
    Anna A. Kuchmiy, Jinke D’Hont, Tino Hochepied, Mohamed Lamkanfi · 2016 · The Journal of Experimental Medicine
75. Guanylate Binding Proteins Regulate Inflammasome Activation in Response to Hyperinjected Yersinia Translocon Components
    Erin E. Zwack, Eric M. Feeley, Amanda R. Burton, Baofeng Hu, Masahiro Yamamoto, Thirumala‐Devi Kanneganti, James B. Bliska, Jörn Coers, Igor E. Brodsky · 2017 · Infection and Immunity
76. Gene set correlation enrichment analysis for interpreting and annotating gene expression profiles
    Lan-Yun Chang, Meng-Zhan Lee, Yujia Wu, Wen-Kai Lee, Chia-Liang Ma, Jun-Mao Chang, Ciao-Wen Chen, Tzu-Chun Huang, Chia‐Hwa Lee, Jih‐Chin Lee et al. · 2023 · Nucleic Acids Research
77. Endoplasmic reticulum stress may activate NLRP3 inflammasomes via TXNIP in preeclampsia
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78. BMSC-derived exosomes alleviate smoke inhalation lung injury through blockade of the HMGB1/NF-κB pathway
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79. Cell death as part of innate immunity: Cause or consequence?
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80. Transcriptome profiling reveals differential expression of immune-related genes in gills of hybrid yellow catfish (Tachysurus fulvidraco ♀ × Pseudobagrus vachellii ♂) under hypoxic stress: Potential NLR-mediated immune response
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81. Hepatoprotection by Ginsenoside Rg1 in alcoholic liver disease
    Cheng Ning Yang, Xiaoqing He, Jinqiu Zhao, Wenxiang Huang · 2021 · International Immunopharmacology
82. Disease-Modifying Anti-rheumatic Drug Prescription Baihu-Guizhi Decoction Attenuates Rheumatoid Arthritis via Suppressing Toll-Like Receptor 4-mediated NLRP3 Inflammasome Activation
    Weijie Li, Xia Mao, Xiaoyue Wang, Yudong Liu, Kexin Wang, Congchong Li, Taixian Li, Yanqiong Zhang, Na Lin · 2021 · Frontiers in Pharmacology
83. Structural insights into the MDP binding and CARD-CARD interaction in zebrafish (Danio rerio) NOD2: a molecular dynamics approach
    Jitendra Maharana, Mahesh Chandra Patra, Bidhan Chandra De, Bikash Ranjan Sahoo, Bijay Kumar Behera, Sachinandan De, Sukanta Kumar Pradhan · 2014 · Journal of Molecular Recognition
84. MyD88-Dependent Signaling Contributes to Host Defense against Ehrlichial Infection
    Young‐Sang Koh, Jung‐Eun Koo, Amlan Biswas, Koichi S. Kobayashi · 2010 · PLoS ONE
85. NLRC5 mediates cell proliferation, migration, and invasion by regulating the Wnt/β-catenin signalling pathway in clear cell renal cell carcinoma
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86. NLRC5: A paradigm for NLRs in immunological and inflammatory reaction
    Yuting Wu, Tianlu Shi, Jun Li · 2019 · Cancer Letters
87. Genetic association of NALP1 with generalized vitiligo in Jordanian Arabs
    Asem M. Alkhateeb, Firas Al‐Qarqaz · 2010 · Archives of Dermatological Research
88. Inflammation research sails through the sea of immunology to reach immunometabolism
    Vijay Kumar · 2019 · International Immunopharmacology
89. Induction and Function of IFNβ During Viral and Bacterial Infection
    Uma M. Nagarajan · 2011 · Critical Reviews in Immunology
90. Non-alcoholic steatohepatitis in morbidly obese patients
    Albert Tran, Philippe Gual · 2013 · Clinics and Research in Hepatology and Gastroenterology
91. Using cell fate attractors to uncover transcriptional regulation of HL60 neutrophil differentiation
    Albert C. Huang, Limei Hu, Stuart Alan Kauffman, Wei Zhang, Ilya Shmulevich · 2009 · BMC Systems Biology
92. Looking for Pyroptosis‐Modulating miRNAs as a Therapeutic Target for Improving Myocardium Survival
    Seahyoung Lee, Eunhyun Choi, Min‐Ji Cha, Ki‐Chul Hwang · 2015 · Mediators of Inflammation
93. Hypoxic stress: impact on the modulation of TLR2, TLR4, NOD1 and NOD2 receptor and their down-stream signalling genes expression in catla (Catla catla)
    Madhubanti Basu, Mahismita Paichha, Saswati S. Lenka, Rina Chakrabarty, Mrinal Samanta · 2015 · Molecular Biology Reports
94. Identification and Classification of Differentially Expressed Genes and Network Meta-Analysis Reveals Potential Molecular Signatures Associated With Tuberculosis
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95. Bacterial death and TRADD-N domains help define novel apoptosis and immunity mechanisms shared by prokaryotes and metazoans
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96. Host cell death machinery as a target for bacterial pathogens
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97. Inflammasome-Independent NLRP3 Restriction of a Protective Early Neutrophil Response to Pulmonary Tularemia
    Sivakumar Periasamy, Hongnga T. Le, Ellen B. Duffy, Heather Chin, Jonathan A. Harton · 2016 · PLoS Pathogens
98. Uncoupling of Pyrin-only Protein 2 (POP2)-mediated Dual Regulation of NF-κB and the Inflammasome
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99. A genetic association study of NLRP2 and NLRP7 genes in idiopathic recurrent miscarriage
    Jyun-Yuan Huang, Mei‐Tsz Su, Sheng‐Hsiang Lin, Pao‐Lin Kuo · 2013 · Human Reproduction
100. NLRP7 contributes to in vitro decidualization of endometrial stromal cells
     Jyun-Yuan Huang, Pei‐Hsiu Yu, Yueh-Chun Li, Pao‐Lin Kuo · 2017 · Reproductive Biology and Endocrinology