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Cited by 668

The DOI matches its Crossref record; 186 of the 186 references it cites were found in a registry or an index.

The molecular basis for centromere identity and function

Open access
McKinley, Kara L., Cheeseman, Iain M.·2016·Nature Reviews Molecular Cell Biology

Abstract

The centromere is the region of the chromosome that directs its segregation in mitosis and meiosis. Although the functional importance of the centromere has been appreciated for more than 130 years, elucidating the molecular features and properties that enable centromeres to orchestrate chromosome segregation is an ongoing challenge. Most eukaryotic centromeres are defined epigenetically and require the presence of nucleosomes containing the histone H3 variant centromere protein A (CENP-A; also known as CENH3). Ongoing work is providing important molecular insights into the central requirements for centromere identity and propagation, and the mechanisms by which centromeres recruit kinetochores to connect to spindle microtubules.

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Crossref · 10.1038/nrm.2015.5

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Metadata

Authors
McKinley, K. L., & Cheeseman, I. M.
Venue
Nature Reviews Molecular Cell Biology
Published
2015-11-25
Volume
17
Issue
1
Pages
16-29
ISSN
  • 1471-0072 (ISSN-L)
  • 1471-0080
OpenAlex
W2175830921
Cited by
668
References
186
FWCI
3.06
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The molecular basis for centromere identity and function. https://app.cochat.ai/papers/10.1038/nrm.2015.5
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McKinley, K. L., & Cheeseman, I. M. (2016). The molecular basis for centromere identity and function. Nature Reviews Molecular Cell Biology. https://doi.org/10.1038/nrm.2015.5

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.