The DOI matches its Crossref record; 147 of the 147 references it cites were found in a registry or an index.
Planar cell polarity in development and disease
Open accessAbstract
Planar cell polarity (PCP) is an essential feature of animal tissues, whereby distinct polarity is established within the plane of a cell sheet. Tissue-wide establishment of PCP is driven by multiple global cues, including gradients of gene expression, gradients of secreted WNT ligands and anisotropic tissue strain. These cues guide the dynamic, subcellular enrichment of PCP proteins, which can self-assemble into mutually exclusive complexes at opposite sides of a cell. Endocytosis, endosomal trafficking and degradation dynamics of PCP components further regulate planar tissue patterning. This polarization propagates throughout the whole tissue, providing a polarity axis that governs collective morphogenetic events such as the orientation of subcellular structures and cell rearrangements. Reflecting the necessity of polarized cellular behaviours for proper development and function of diverse organs, defects in PCP have been implicated in human pathologies, most notably in severe birth defects.
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Cites
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Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation
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Dishevelled controls cell polarity during Xenopus gastrulation
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Self-citationCell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium of Drosophila
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Principles of planar polarity in animal development
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The role of RhoA in tissue polarity and Frizzled signalling
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Cited by
Programmed and self-organized flow of information during morphogenesis
Collinet, C., & Lecuit, T. (2021) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-00318-6 · Cited by 322
Endocytosis in the context-dependent regulation of individual and collective cell properties
Sigismund, S., Lanzetti, L., Scita, G., & Di Fiore, P. P. (2021) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-021-00375-5 · Cited by 132
Regulation of cell polarity by cell adhesion receptors
Ebnet, K., Kummer, D., Steinbacher, T., Singh, A., Nakayama, M., & Matis, M. (2018) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2017.07.032 · Cited by 52
Metadata
- Authors
- Butler, M. T., & Wallingford, J. B.
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2017-03-15
- Volume
- 18
- Issue
- 6
- Pages
- 375-388
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W2599641104
- Cited by
- 580
- References
- 147
- FWCI
- 3.40
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
