Parsing the Polarity Code

Macara, Ian G.·2004·Nature Reviews Molecular Cell Biology

Cited by (340)

Items 201–300 of 340

  1. Overview of junctional complexes during mammalian early embryonic development
    Ceren Canse, Ecem Yıldırım, Aylin Yaba · 2023 · Frontiers in Endocrinology
  2. Par6 is phosphorylated by aPKC to facilitate EMT
    Adrian Gunaratne, Gianni M. Di Guglielmo · 2013 · Cell Adhesion & Migration
  3. The Snakeskin-Mesh Complex of Smooth Septate Junction Restricts Yorkie to Regulate Intestinal Homeostasis in Drosophila
    Hsi‐Ju Chen, Qi Li, Niraj K. Nirala, Yicktung Tony Ip · 2020 · Stem Cell Reports
  4. LIMK1 and LIMK2 regulate cortical development through affecting neural progenitor cell proliferation and migration
    Rui Mao, Rui Deng, Yan Wei, Lifang Han, Yanghong Meng, Wei Xie, Zhengping Jia · 2019 · Molecular Brain
  5. Cell polarity signalling at the birth of multicellularity: What can we learn from the first animals
    Bree A. Wright, Marc Kvansakul, Bernd Schierwater, Patrick Orson Humbert · 2022 · Frontiers in Cell and Developmental Biology
  6. Interactions between Cdc42 and the scaffold protein Scd2: requirement of SH3 domains for GTPase binding
    Edward R. Wheatley, Katrin Rittinger · 2005 · Biochemical Journal
  7. Autoactivation of small GTPases by the GEF–effector positive feedback modules
    Andrew Boris Goryachev, Marcin Leda · 2019 · F1000Research
  8. Phosphoinositide Binding by Par-3 Involved in Par-3 Localization
    Yosuke Horikoshi, Sayaka Hamada, Shigeo Ohno, Shiro Suetsugu · 2011 · Cell Structure and Function
  9. Ovarian cancer: Homeobox genes, autocrine/paracrine growth, and kinase signaling
    Bryan T. Hennessy, Gordon Brent Mills · 2006 · The International Journal of Biochemistry & Cell Biology
  10. The aPKCι blocking agent ATM negatively regulates EMT and invasion of hepatocellular carcinoma
    C. Q., Y Yang, Jiacheng Wang, G S Du, Qiong “John” Shen, Y Liu, J Zhang, Junbo Hu, Peng Zhu, W P Qi et al. · 2014 · Cell Death and Disease
  11. MARK2/Par-1 guides the directionality of neuroblasts migrating to the olfactory bulb
    Sheyla Mejia‐Gervacio, Kerren Murray, Tamar Sapir, Richard Belvindrah, Orly Reiner, Pierre‐Marie Lledo · 2011 · Molecular and Cellular Neuroscience
  12. The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell division
    Ewa Stypulkowski, Irfan Ahmed Asangani, Eric S. Witze · 2018 · Science Signaling
  13. Atypical Protein Kinase C and Par3 Are Required for Proteoglycan-Induced Axon Growth Inhibition
    Seong-il Lee, Weibing Zhang, Mayuri Ravi, Markus Weschenfelder, Martin Bastmeyer, Joel M. Levine · 2013 · Journal of Neuroscience
  14. aPKC restricts the basolateral determinant PtdIns(3,4,5)P3 to the basal region
    Shoukichi Takahama, Tomonori Hirose, Shigeo Ohno · 2008 · Biochemical and Biophysical Research Communications
  15. Raf‐1 levels determine the migration rate of primary endometrial stromal cells of patients with endometriosis
    Iveta Yotova, Ping Quan, Aulona Gaba, Nadja Leditznig, Petra Pateisky, Christine Kurz, Walter Tschugguel · 2012 · Journal of Cellular and Molecular Medicine
  16. Mark/Par-1 Marking the Polarity of Migrating Neurons
    Orly Reiner, Tamar Sapir · 2013 · Advances in experimental medicine and biology
  17. VE-cadherin interacts with cell polarity protein Pals1 to regulate vascular lumen formation
    B. Brinkmann, Tim Steinbacher, Christian Hartmann, Daniel Kummer, Denise Pajonczyk, Fatemeh Mirzapourshafiyi, Masanori Nakayama, Thomas Weide, Volker Gerke, Klaus Ebnet · 2016 · Molecular Biology of the Cell
  18. Par system components are asymmetrically localized in ectodermal epithelia, but not during early development in the sea anemone Nematostella vectensis
    Miguel Salinas‐Saavedra, Thomas Q Stephenson, Casey W. Dunn, Mark Q. Martindale · 2015 · EvoDevo
  19. Isoform‐specific interaction of Flamingo/Starry Night with excess Bazooka affects planar cell polarity in the Drosophila wing
    Isabel Wasserscheid, Ulrich Thomas, Elisabeth Knust · 2007 · Developmental Dynamics
  20. PAR-6, but not E-cadherin and β-integrin, is necessary for epithelial polarization in C. elegans
    Stephen E. Von Stetina, Susan E. Mango · 2015 · Developmental Biology
  21. C. elegans Brat homologs regulate PAR protein-dependent polarity and asymmetric cell division
    Vincent Hyenne, Marianne Desrosiers, Jean-Claude Labbé · 2008 · Developmental Biology
  22. Spatial‐temporal expressions of Crumbs and Nagie oko and their interdependence in zebrafish central nervous system during early development
    Jian Zou, Yi Wen, Xiaojun Yang, Xiangyun Wei · 2013 · International Journal of Developmental Neuroscience
  23. Aberrant expression of the polarity complex atypical PKC and non-muscle myosin IIA in active and inactive inflammatory bowel disease
    Flavia A. Wald, Radia Forteza, Runa Diwadkar-Watkins, Anastasia Mashukova, ROBERT C. DUNCAN, Maria Teresa Abreu, Pedro J. I. Salas · 2011 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  24. Cadherin‐Mediated Regulation of Tight Junctions in Stratifying Epithelia
    Christian Michels, Saeed Yadranji Aghdam, Carien M. Niessen · 2009 · Annals of the New York Academy of Sciences
  25. Structural insights into the aPKC regulatory switch mechanism of the human cell polarity protein lethal giant larvae 2
    Lior Almagor, Ivan S. Ufimtsev, Aruna Ayer, Jingzhi Li, William I. Weis · 2019 · Proceedings of the National Academy of Sciences
  26. lethal giant larvaeis required with thepargenes for the early polarization of theDrosophilaoocyte
    Pierre Fichelson, Marlène Jagut, Sophie Le Panse, Jean‐Antoine Lepesant, Jean‐René Huynh · 2010 · Development
  27. Translation of Molecular Order to the Macroscopic Level
    ALBERTO CIFERRI · 2015 · Chemical Reviews
  28. Rabs set the stage for polarity
    Sara S. Parker, Christopher M. Cox, Jean M. Wilson · 2017 · Small GTPases
  29. Epithelial junctions and polarity: complexes and kinases
    Michael J. Caplan, Patricia W. Seo-Mayer, Li Zhang · 2008 · Current Opinion in Nephrology & Hypertension
  30. Closing the GAP between Polarity and Vesicle Transport
    Ian G. Macara, Anne Spang · 2006 · Cell
  31. Substrate Stiffness Determines the Establishment of Apical-Basal Polarization in Renal Epithelial Cells but Not in Tubuloid-Derived Cells
    Maria J. Hagelaars, Fjodor A. Yousef Yengej, Marianne Christina Verhaar, Maarten B. Rookmaaker, Sandra Loerakker, Carlijn V. C. Bouten · 2022 · Frontiers in Bioengineering and Biotechnology
  32. Cell-to-Cell Heterogeneity in Cortical Tension Specifies Curvature of Contact Surfaces in Caenorhabditis elegans Embryos
    Masashi Fujita, Shuichi Onami · 2012 · PLoS ONE
  33. Mechanisms of cell polarity and aquaporin sorting in the nephron
    Bayram Edemir, Hermann Josef Pavenstädt, Eberhard Schlatter, Thomas Weide · 2011 · Pflügers Archiv - European Journal of Physiology
  34. Actin-Binding Proteins and Disease
    C.G. dos Remedios, Deepak Chhabra · 2008 · Springer eBooks
  35. p210Bcr−Abl desensitizes Cdc42 GTPase signaling for SDF-1α-directed migration in chronic myeloid leukemia cells
    Y -C Chang, S -C Tien, Hwei‐Fang Tien, H Zhang, Gary Bokoch, Z -F Chang · 2009 · Oncogene
  36. Phosphorylation-dependent binding of 14-3-3 to Par3β, a human Par3-related cell polarity protein
    Tomoko Izaki, Sachiko Kamakura, Motoyuki Kohjima, Hideki Sumimoto · 2005 · Biochemical and Biophysical Research Communications
  37. Cell Migration in Microfabricated 3D Collagen Microtracks is Mediated Through the Prometastatic Protein Girdin
    Aniqua Rahman-Zaman, Shuo Shan, Cynthia A. Reinhart‐King · 2017 · Cellular and Molecular Bioengineering
  38. Collective Migrations of Drosophila Embryonic Trunk and Caudal Mesoderm-Derived Muscle Precursor Cells
    Jingjing Sun, Frank Macabenta, Zsuzsa Ákos, Angelike Stathopoulos · 2020 · Genetics
  39. Aberrant phosphorylation inactivates Numb in breast cancer causing expansion of the stem cell pool
    Maria Grazia Filippone, Stefano Freddi, Silvia Zecchini, Silvia Restelli, Ivan Nicola Colaluca, Giovanni Bertalot, Salvatore Pece, Daniela Tosoni, Pier Paolo Di Fiore · 2022 · The Journal of Cell Biology
  40. Human cytomegalovirus immediate-early-gene expression disrupts embryogenesis in transgenic Drosophila
    R. Steinberg, Y. Shemer-Avni, Noa Adler, Shira Neuman-Silberberg · 2008 · Transgenic research
  41. Partial Functional Diversification ofDrosophila melanogasterSeptin GenesSep2andSep5
    Ryan S. O’Neill, Denise V. Clark · 2016 · G3 Genes Genomes Genetics
  42. CDC-42 Interactions with Par Proteins Are Critical for Proper Patterning in Polarization
    Sungrim Seirin‐Lee, Eamonn A. Gaffney, Adriana T. Dawes · 2020 · Cells
  43. Cell Polarity in the Anulus of the Human Intervertebral Disc
    Helen E. Gruber, Jane A. Ingram, Gretchen L. Hoelscher, H. James Norton, Edward N. Hanley · 2007 · Spine
  44. RNA Interference Techniques to Study Epithelial Cell Adhesion and Polarity
    Xinyu Chen, Ian G. Macara · 2006 · Methods in enzymology on CD-ROM/Methods in enzymology
  45. Therapeutic Effectiveness of Anticancer Agents Targeting Different Signaling Molecules Involved in Asymmetric Division of Cancer Stem Cell
    Priya Samanta, Arijit Bhowmik, Souradeep Biswas, Rupali Sarkar, Rituparna Ghosh, Shampa Pakhira, Mrinmoyee Mondal, Soummadeep Sen, Prosenjit Saha, Subhadip Hajra · 2023 · Stem Cell Reviews and Reports
  46. Progenitor Epithelium
    Leilani Marty‐Santos, Ondine B. Cleaver · 2015 · Journal of Histochemistry & Cytochemistry
  47. Ordered Multisite Phosphorylation of Lethal Giant Larvae by Atypical Protein Kinase C
    Chiharu Graybill, Kenneth E. Prehoda · 2014 · Biochemistry
  48. Force-Induced Polarized Mitosis of Endothelial and Smooth Muscle Cells in Arterial Remodeling
    Dorota Dajnowiec, Peter J. B. Sabatini, Thea Van Rossum, Jacky T.K. Lam, Ming Zhang, András Kapùs, B. Lowell Langille · 2007 · Hypertension
  49. Compartmentalization in T‐cell signalling: Membrane microdomains and polarity orchestrate signalling and morphology
    Sarah May Russell, Jane Oliaro · 2006 · Immunology and Cell Biology
  50. Capture, mutual inhibition and release mechanism for aPKC–Par6 and its multisite polarity substrate Lgl
    Christopher P. Earl, Mathias Cobbaut, André Barros-Carvalho, Marina E. Ivanova, David C. Briggs, Eurico Morais‐de‐Sá, Peter J. Parker, Neil Q. McDonald · 2025 · Nature Structural & Molecular Biology
  51. Upregulation of OASIS/CREB3L1 in podocytes contributes to the disturbance of kidney homeostasis
    Yoshiaki Miyake, Masanori Obana, Ayaha Yamamoto, Shunsuke Noda, Koki Tanaka, Hibiki Sakai, Narihito Tatsumoto, Chihiro Makino, Soshi Kanemoto, Go Shioi et al. · 2022 · Communications Biology
  52. Hepatocyte Growth Factor stimulated cell scattering requires ERK and Cdc42-dependent tight junction disassembly
    Akashi Togawa, Jeff Sfakianos, Shuta Ishibe, Sayuri Suzuki, Yoshihide Fujigaki, Masatoshi Kitagawa, Ira Mellman, Lloyd G. Cantley · 2010 · Biochemical and Biophysical Research Communications
  53. Par protein localization during the early development of Mnemiopsis leidyi suggests different modes of epithelial organization in the metazoa
    Miguel Salinas‐Saavedra, Mark Q. Martindale · 2020 · eLife
  54. PAR-1 and the microtubule-associated proteins CLASP2 and dynactin-p50 have specific localisation on mouse meiotic and first mitotic spindles
    Catherine A Moore, Magdalena Zernicka‐Goetz · 2005 · Reproduction
  55. The asymmetric cell division machinery in the spiral-cleaving egg and embryo of the marine annelid Platynereis dumerilii
    Aron Nakama, Hsien-Chao Chou, Stephan Schneider · 2017 · BMC Developmental Biology
  56. Apical-Basal Polarity Signaling Components, Lgl1 and aPKCs, Control Glutamatergic Synapse Number and Function
    John C. Scott, Sonal Thakar, Mao Ye, Huaping Qin, Helen Hejran, Su-Yee J. Lee, Ting Yu, Olga Klezovitch, Hongqiang Cheng, Yongxin Mu et al. · 2019 · iScience
  57. Role of Cell-Cell Junctions in Oesophageal Squamous Cell Carcinoma
    Qian-Rui Xu, Xiaohui Du, Tingting Huang, Yu-Chun Zheng, Yuling Li, Dan-Yi Huang, Hao‐Qiang Dai, En‐Min Li, Wang‐Kai Fang · 2022 · Biomolecules
  58. The Role of PB1 Domain Proteins in Endothelial Cell Dysfunction and Disease
    Ryan M. Burke, Bradford C. Berk · 2015 · Antioxidants and Redox Signaling
  59. ADF/Cofilin, Actin Dynamics, and Disease
    Michael T. Maloney, Andrew W. Kinley, Chi W. Pak, James R. Bamburg · 2008 · Springer eBooks
  60. CNTNAP2 is targeted to endosomes by the polarity protein PAR3
    Ruoqi Gao, Christopher P. Pratt, Sehyoun Yoon, María Dolores Martin‐de‐Saavedra, Marc P. Forrest, Peter Penzes · 2019 · European Journal of Neuroscience
  61. Dendritic spine plasticity as an underlying mechanism of neuropathic pain: Commentary on Tan et al.
    Ohannes K. Melemedjian, Theodore John Price · 2011 · Experimental Neurology
  62. Expression and functional characterization of a Rho-family small GTPase CDC42 from Trichinella spiralis
    Yurong Yang, Weiwen Qin, Guimei Tian, Wei Jian · 2010 · Parasitology Research
  63. Loss of PAR-3 protein expression is associated with invasion, lymph node metastasis, and poor survival in esophageal squamous cell carcinoma
    Tomoko Kitaichi, Kohichiroh Yasui, Yasuyuki Gen, Osamu Dohi, N. Iwai, Akira Tomie, Nobuhisa Yamada, Kei Terasaki, Atsushi Umemura, Taichiro Nishikawa et al. · 2017 · Human Pathology
  64. Development of novel agents for ovarian cancer
    Bryan T. Hennessy, Maurie M. Markman · 2009 · Update on Cancer Therapeutics
  65. Implication of Wnt signaling in neuronal polarization
    Guoying Yang, Zhen‐Ge Luo · 2010 · Developmental Neurobiology
  66. JAM-A and aPKC
    Klaus Ebnet · 2013 · Tissue Barriers
  67. Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1
    Thüring, Eva-Maria, Hartmann, Christian, Maddumage, Janesha C., Javorsky, Airah, Michels, Birgitta E., Gerke, Volker, Banks, Lawrence, Humbert, Patrick O., Kvansakul, Marc, Ebnet, Klaus · 2023 · Communications Biology
  68. Intragraft gene expression profile associated with the induction of tolerance by allochimeric MHC I in the rat heart transplantation model
    Wojciech Lisik, Yongquan Gong, Neelam Tejpal, T. Spencer Skelton, Eric G. Bremer, Małgorzata Kloc, Rafik Mark Ghobrial · 2009 · genesis
  69. Asymmetric and Unequal Cell Divisions in Ascidian Embryos
    Takefumi Negishi, Hiroki Nishida · 2017 · Results and problems in cell differentiation
  70. Ric-8A, a GEF for heterotrimeric G-proteins, controls cranial neural crest cell polarity during migration
    Juan Ignacio Leal, Soraya Villaseca, Andréa Beyer, Gabriela Toro-Tapia, Marcela Torrejón · 2018 · Mechanisms of Development
  71. Engineering Strategies to Move from Understanding to Steering Renal Tubulogenesis
    Maria J. Hagelaars, Laura Rijns, Patricia Y. W. Dankers, Sandra Loerakker, Carlijn V. C. Bouten · 2022 · Tissue Engineering Part B Reviews
  72. Nuclear localization of the zebrafish tight junction protein nagie oko
    Nana Bit‐Avragim, Stefan Rohr, Franziska Rudolph, Peter F. M. van der Ven, Dieter O. Fürst, Jenny Eichhorst, Burkhard Wiesner, Salim Abdelilah‐Seyfried · 2007 · Developmental Dynamics
  73. Polarity Determinants in Dendritic Spine Development and Plasticity
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  74. Regulation of aPKC activity by Nup358 dependent SUMO modification
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  75. Spermiation: Insights from Studies on the Adjudin Model
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  76. Inhibition of negative feedback for persistent epithelial cell–cell junction contraction by p21-activated kinase 3
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  77. CCM1 and the second life of proteins in adhesion complexes
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  78. RhoGDI1 regulates cell-cell junctions in polarized epithelial cells
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  79. A modifier screen in the Drosophila eye reveals that aPKC interacts with Glued during central synapse formation
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  80. Protein Kinase C Modulation Determines the Mesoderm/Extraembryonic Fate Under BMP4 Induction From Human Pluripotent Stem Cells
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  81. Methods in Cell Biology: Analysis of Cell Polarity in C. elegans Embryos
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  82. Vesicular sorting controls the polarity of expanding membranes in theC. elegansintestine
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  84. Cyclooxygenase-2 regulates HPS patient serum induced-directional collective HPMVEC migration via PKC/Rac signaling pathway
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  85. Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye
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  86. The double (strand break) life of Par-3
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  88. Cytokinesis and the establishment of early embryonic cell polarity
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  89. Prickle1‐driven basement membrane deposition of the iPSC ‐derived embryoid bodies is separable from the establishment of apicobasal polarity
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  93. Epithelial Cell Structure and Polarity
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  99. Diamond controls epithelial polarity through the dynactin‐dynein complex
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