Parsing the Polarity Code

Macara, Ian G.·2004·Nature Reviews Molecular Cell Biology

DOI 10.1038/nrm1332

Cited by (340)

Items 101–200 of 340

Defective expression of polarity protein PAR-3 gene (PARD3) in esophageal squamous cell carcinoma
Keika Zen, K Yasui, Yasuyuki Gen, Osamu Dohi, Naoto Wakabayashi, Shoji Mitsufuji, Yoshito Itoh, Yoh Zen, Yasuni Nakanuma, Masafumi Taniwaki et al. · 2009 · Oncogene
Cell-Cell Adhesion in the Cnidaria: Insights Into the Evolution of Tissue Morphogenesis
Craig R. Magie, Mark Q. Martindale · 2008 · Biological Bulletin
Analysis of detergent-resistant membranes of Helicobacter pylori infected gastric adenocarcinoma cells reveals a role for MARK2/Par1b in CagA-mediated disruption of cellular polarity
Zaher Zeaiter, David Cohen, Anne Müsch, Fábio Bagnoli, Antonello Covacci, Markus Stein · 2008 · Cellular Microbiology
The MAGUK Protein MPP7 Binds to the Polarity Protein hDlg1 and Facilitates Epithelial Tight Junction Formation
Volker M. Stucke, Evy Timmerman, Joel S. Vandekerckhove, Kris Gevaert, Alan Hall · 2007 · Molecular Biology of the Cell
Clinical reviews in allergy and immunology
Donald Y.M. Leung, Dennis K. Ledford, Michael E. Wechsler, Patricia C. Fulkerson, Bruce Scott Bochner, Gail M. Gauvreau, Gerald J. Gleich, Tim Henkel, Roland Kolbeck, Sameer K. Mathur et al. · 2012
Non-canonical Wnt signaling regulates cell polarity in female reproductive tract development via van gogh-like 2
Alysia L. vandenBerg, David A. Sassoon · 2009 · Development
The polarity‐inducing kinase Par‐1 controls Xenopus gastrulation in cooperation with 14‐3‐3 and aPKC
Morioh Kusakabe, Eisuke Nishida · 2004 · The EMBO Journal
Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly
Xinyu Chen, Ian G. Macara · 2006 · The Journal of Cell Biology
Structure of a Cell Polarity Regulator, a Complex between Atypical PKC and Par6 PB1 Domains
Yoshinori Hirano, Sosuke Yoshinaga, Ryu Takeya, Nobuo N. Suzuki, Masataka Horiuchi, Motoyuki Kohjima, Hideki Sumimoto, Fuyuhiko Inagaki · 2004 · Journal of Biological Chemistry
Tumor Necrosis Factor Alpha and Inflammation Disrupt the Polarity Complex in Intestinal Epithelial Cells by a Posttranslational Mechanism
Anastasia Mashukova, Flavia A. Wald, Pedro J. I. Salas · 2010 · Molecular and Cellular Biology
Complex Polarity: Building Multicellular Tissues Through Apical Membrane Traffic
Álvaro Román‐Fernández, David M. Bryant · 2016 · Traffic
PAR3 acts as a molecular organizer to define the apical domain of chick neuroepithelial cells
Cristina Afonso, Domingos Henrique · 2006 · Journal of Cell Science
Junctional adhesion molecule-A participates in the formation of apico-basal polarity through different domains
Daniela Rehder, Sandra Iden, Ines Nasdala, Joachim Wegener, Maria-Katharina Meyer zu Brickwedde, Dietmar Vestweber, Klaus Ebnet · 2006 · Experimental Cell Research
The apical/basal-polarity determinant Scribble cooperates with the PCP core factor Stbm/Vang and functions as one of its effectors
Courbard, Jean-Remy, Djiane, Alexandre, Wu, Jun, Mlodzik, Marek · 2009 · Developmental Biology
Regulation of membrane trafficking in polarized epithelial cells
Heike Fölsch · 2008 · Current Opinion in Cell Biology
PATJ regulates directional migration of mammalian epithelial cells
Kunyoo Shin, Qian Wang, Ben L. Margolis · 2007 · EMBO Reports
The Tangled Web of Non-Canonical Wnt Signalling in Neural Migration
Charlotte Clark, C. Cathrin Nourse, Helen M. Cooper · 2012 · Neurosignals
Atypical Protein Kinase C Phosphorylates Par6 and Facilitates Transforming Growth Factor β-Induced Epithelial-to-Mesenchymal Transition
Adrian Gunaratne, Boun Thai, Gianni M. Di Guglielmo · 2012 · Molecular and Cellular Biology
CED-10/Rac1 Mediates Axon Guidance by Regulating the Asymmetric Distribution of MIG-10/Lamellipodin
Christopher C. Quinn, Douglas S. Pfeil, William G. Wadsworth · 2008 · Current Biology
A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development
Hirotaka Tao, Miyuki Shimizu, Ryo Kusumoto, Katsuhiko Ono, Sumihare Noji, Hideyo Ohuchi · 2005 · Development
Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling
Yiguo Wang, Dan Du, Longhou Fang, Guang Yang, Chenyi Zhang, Rong Zeng, Axel Ullrich, Friedrich Lottspeich, Zhengjun Chen · 2006 · The EMBO Journal
HEF1-Aurora A Interactions: Points of Dialog between the Cell Cycle and Cell Attachment Signaling Networks
Elena N. Pugacheva, Erica A. Golemis · 2006 · Cell Cycle
Physiological functions of junctional adhesion molecules (JAMs) in tight junctions
Christian Hartmann, Ysabel Alessa Schwietzer, Tetsuhisa Otani, Mikio Furuse, Klaus Ebnet · 2020 · Biochimica et Biophysica Acta (BBA) - Biomembranes
Differential methylation is associated with non-syndromic cleft lip and palate and contributes to penetrance effects
Lucas Alvizi, Xiayi Ke, Luciano Abreu Brito, Rimante Seselgyte, Gudrun E. Moore, Philip Stanier, Maria Rita Passos‐Bueno · 2017 · Scientific Reports
Linking epithelial polarity and carcinogenesis by multitasking Helicobacter pylori virulence factor CagA
Masanori Hatakeyama · 2008 · Oncogene
Localized PEM mRNA and Protein Are Involved in Cleavage-Plane Orientation and Unequal Cell Divisions in Ascidians
Takefumi Negishi, Tatsuki Takada, Narudo Kawai, Hiroki Nishida · 2007 · Current Biology
Polarity proteins and Rho GTPases cooperate to spatially organise epithelial actin-based protrusions
Μάριος Γεωργίου, Buzz Baum · 2010 · Journal of Cell Science
Dynein-mediated apical localization of crumbs transcripts is required for Crumbs activity in epithelial polarity
Zhouhua Li, Liwei Wang, Thomas S. Hays, Yu Cai · 2008 · The Journal of Cell Biology
Junctional adhesion molecule-A: functional diversity through molecular promiscuity
Tim Steinbacher, Daniel Kummer, Klaus Ebnet · 2017 · Cellular and Molecular Life Sciences
Dual Role of Cdc42 in Spindle Orientation Control of Adherent Cells
Masaru Mitsushima, Fumiko Toyoshima, Eisuke Nishida · 2009 · Molecular and Cellular Biology
Computer modelling in combination with in vitro studies reveals similar binding affinities of Drosophila Crumbs for the PDZ domains of Stardust and DmPar-6
Özlem Kempkens, Emmanuelle Médina, Gregorio J. Fernandez-Ballester, Susann Özüyaman, André Le Bivic, Luis G. Serrano, Elisabeth Knust · 2006 · European Journal of Cell Biology
PAR-1 Phosphorylates Mind Bomb to Promote Vertebrate Neurogenesis
Olga Ossipova, Jérôme Ezan, Sergei Y. Sokol · 2009 · Developmental Cell
Cell cycle entry triggers a switch between two modes of Cdc42 activation during yeast polarization
Kristen Witte, Devin Strickland, Michael Glotzer · 2017 · eLife
Shp2 promotes metastasis of prostate cancer by attenuating the PAR3/PAR6/aPKC polarity protein complex and enhancing epithelial-to-mesenchymal transition
Kai Zhang, H Zhao, Zhongzhong Ji, C Zhang, P Zhou, L Wang, Qiuyi Chen, Jia Wang, P Zhang, Zhaolin Chen et al. · 2015 · Oncogene
Helicobacter pylori CagA Causes Mitotic Impairment and Induces Chromosomal Instability
Mayumi Umeda, Naoko Murata‐Kamiya, Yasuhiro Saito, Yusuke Ohba, Masayuki Takahashi, Masanori Hatakeyama · 2009 · Journal of Biological Chemistry
The aPKC–PAR-6–PAR-3 cell polarity complex localizes to the centrosome attracting body, a macroscopic cortical structure responsible for asymmetric divisions in the early ascidian embryo
Solenn Patalano, Gérard Prulière, François Prodon, Alexandre Paix, Philippe Dru, Christian Sardet, Janet M. Chenevert · 2006 · Journal of Cell Science
Reinterpreting polarity and cancer: The changing landscape from tumor suppression to tumor promotion
Yasuhiro Saito, Ridhdhi Desai, Senthil K. Muthuswamy · 2018 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Regulation of Par6 by extracellular signals
Rohit Bose, Jeffrey L. Wrana · 2006 · Current Opinion in Cell Biology
Cutting Edge: Atypical PKCs Regulate T Lymphocyte Polarity and Scanning Behavior
Eliana Real, Sophie Faure, Emmanuel Donnadieu, Jérôme Delon · 2007 · The Journal of Immunology
Downregulation of Par-3 expression and disruption of Par complex integrity by TGF-β during the process of epithelial to mesenchymal transition in rat proximal epithelial cells
Xiang‐Yang Wang, Jing Nie, Qin Zhou, Wei Liu, Fengxin Zhu, Wei Chen, Haiping Mao, Ning Luo, Xiuqing Dong, Xueqing Yu · 2007 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
A Genomewide Screen for Suppressors of par-2 Uncovers Potential Regulators of PAR Protein-Dependent Cell Polarity in Caenorhabditis elegans
Jean-Claude Labbé, Anne Pacquelet, Thomas Marty, Monica Gotta · 2006 · Genetics
Tight Junctions and the Intestinal Barrier
Thomas Y. Ma, James Melvin Anderson, Jerrold R. Turner · 2012 · Elsevier eBooks
Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood–retinal barrier dysfunction
Paul M. Titchenell, Cheng-Mao Lin, Jason M. Keil, Jeffrey M. Sundstrom, Charles D. Smith, David A. Antonetti · 2012 · Biochemical Journal
PAR-3 defines a central subdomain of the cortical actin cap in mouse eggs
Francesca E. Duncan, Stuart B. Moss, Richard M. Schultz, Carmen J. Williams · 2005 · Developmental Biology
Regulation of myosin activation during cell–cell contact formation by Par3-Lgl antagonism: entosis without matrix detachment
Wan, Qingwen, Liu, Jing, Zheng, Zhen, Zhu, Huabin, Chu, Xiaogang, Dong, Zheng, Huang, Shuang, Du, Quansheng · 2012 · Molecular Biology of the Cell
A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands
Cosmas C. Giallourakis, Zhifang Cao, Todd J. Green, Heather Wachtel, Xiaohui S. Xie, Marco A. Lopez-Ilasaca, Mark J. Daly, John David Rioux, Ramnik J. Xavier · 2006 · Genome Research
TGF-β-induced MiR-491-5p Expression Promotes Par-3 Degradation in Rat Proximal Tubular Epithelial Cells
Qin Zhou, Jinjin Fan, Xuebing Ding, Wenxing Peng, Xueqing Yu, Yujie Chen, Jing Nie · 2010 · Journal of Biological Chemistry
The Centrosomal E3 Ubiquitin Ligase FBXO31-SCF Regulates Neuronal Morphogenesis and Migration
Mayur Vadhvani, Nicola Schwedhelm‐Domeyer, Chaitali Mukherjee, Judith Stegmüller · 2013 · PLoS ONE
Cortical capture of microtubules and spindle polarity in budding yeast - where's the catch?
Stephen M. Huisman, Marisa Segal · 2005 · Journal of Cell Science
ErbB receptors and cell polarity: New pathways and paradigms for understanding cell migration and invasion
Michael E. Feigin, Senthil K. Muthuswamy · 2008 · Experimental Cell Research
Claudin-1 Protein Expression is a Prognostic Marker of Patient Survival in Renal Cell Carcinomas
Florian Rudolf Fritzsche, Beibei Oelrich, Manfred Johannsen, Ilka Kristiansen, Holger Moch, Klaus Jung, Glen Kristiansen · 2008 · Clinical Cancer Research
Regulation of cell polarity by cell adhesion receptors
Ebnet, Klaus, Kummer, Daniel, Steinbacher, Tim, Singh, Amrita, Nakayama, Masanori, Matis, Maja · 2018 · Seminars in Cell & Developmental Biology
Antagonistic Effects of Doublecortin and MARK2/Par-1 in the Developing Cerebral Cortex
Tamar Sapir, Anat Shmueli, Talia Levy, Thomas Timm, Michael Elbaum, Eva‐Maria Mandelkow, Orly Reiner · 2008 · Journal of Neuroscience
Host Cell Polarity Proteins Participate in Innate Immunity to Pseudomonas aeruginosa Infection
Cindy S. Tran, Yoni Eran, Travis R. Ruch, David M. Bryant, Anirban Datta, Paul Brakeman, Arlinet Kierbel, Torsten Wittmann, Ross J. Metzger, Keith E. Mostov et al. · 2014 · Cell Host & Microbe
Involvement of Girdin in the Determination of Cell Polarity during Cell Migration
Kei Ohara, Atsushi Enomoto, Takuya Kato, Takahiko Hashimoto, Mayu Isotani-Sakakibara, Naoya Asai, Maki Takagishi, Liang Weng, Masanori Nakayama, Takashi Watanabe et al. · 2012 · PLoS ONE
Atypical protein kinase C (aPKCζ and aPKCλ) is dispensable for mammalian hematopoietic stem cell activity and blood formation
Amitava Sengupta, Ángeles Durán, Eri Ishikawa, Maria Carolina Florian, Susan K. Dunn, Ashley M. Ficker, Michael Leitges, Hartmut Geiger, Maria Teresa Díaz-Meco, Jorge Moscat et al. · 2011 · Proceedings of the National Academy of Sciences
Cell fate regulation during preimplantation development: A view of adhesion-linked molecular interactions
Berna Sözen, Alp Can, Necdet Demır · 2014 · Developmental Biology
Planar Cell Polarity in the Inner Ear
Helen May‐Simera, Matthew W. Kelley · 2012 · Current topics in developmental biology/Current Topics in Developmental Biology
Par3 is essential for the establishment of planar cell polarity of inner ear hair cells
André Landin Malt, Zachary Dailey, Julia Holbrook-rasmussen, Yuqiong Zheng, Arielle Hogan, Quansheng Du, Xiaowei Lu · 2019 · Proceedings of the National Academy of Sciences
Mechanisms of CDC-42 activation during contact-induced cell polarization
Emily Chan, Jeremy Nance · 2013 · Journal of Cell Science
New insights into regulation and function of planar polarity in the inner ear
Basile Tarchini, Xiaowei Lu · 2019 · Neuroscience Letters
Polarity proteins as regulators of cell junction complexes: Implications for breast cancer
Dana Bazzoun, Sophie A. Lelièvre, Rabih Talhouk · 2013 · Pharmacology & Therapeutics
Establishment of epithelial polarity – GEF who's minding the GAP?
Siu P. Ngok, Wan‐Hsin Lin, Panos Z. Anastasiadis · 2014 · Journal of Cell Science
The Polarity Protein Par1b/EMK/MARK2 Regulates T Cell Receptor-Induced Microtubule-Organizing Center Polarization
Joseph Lin, Kirk K. Hou, Helen M. Piwnica-Worms, Andréy S. Shaw · 2009 · The Journal of Immunology
Different domains of C. elegans PAR-3 are required at different times in development
Bingsi Li, Heon Kim, Melissa A. Beers, Kenneth J. Kemphues · 2010 · Developmental Biology
Modeling the Establishment of PAR Protein Polarity in the One-Cell C. elegans Embryo
Filipe Tostevin, Martin Howard · 2008 · Biophysical Journal
Cell-autonomous and environmental contributions to the interstitial migration of T cells
Paulus Mrass, Janka Petravic, Miles P. Davenport, Wolfgang Weninger · 2010 · Seminars in Immunopathology
Asymmetric cell division of stem cells in the lung and other systems
Mohamed Y. Berika, Marwa E. Elgayyar, Ahmed H. K. El-Hashash · 2014 · Frontiers in Cell and Developmental Biology
aPKC enables development of zonula adherens by antagonizing centripetal contraction of the circumferential actomyosin cables
Masaru Kishikawa, Atsushi Suzuki, Shigeo Ohno · 2008 · Journal of Cell Science
ZOning out Tight Junctions
Kunyoo Shin, Ben L. Margolis · 2006 · Cell
Polycystic kidney disease: The complexity of planar cell polarity and signaling during tissue regeneration and cyst formation
Hester Happé, Emile de Heer, Dorien J.M. Peters · 2011 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Wnt signaling and neurite outgrowth: Insights and questions
Endo, Yoshimi, Rubin, Jeffrey S. · 2007 · Cancer Science
Rab5-mediated VE-cadherin internalization regulates the barrier function of the lung microvascular endothelium
Junjun Yang, Wei Yao, Guisheng Qian, Zhenghua Wei, Guangyu Wu, Guansong Wang · 2015 · Cellular and Molecular Life Sciences
PAR-3 and PAR-1 Inhibit LET-99 Localization to Generate a Cortical Band Important for Spindle Positioning inCaenorhabditis elegansEmbryos
Jui-Ching Wu, Lesilee S. Rose · 2007 · Molecular Biology of the Cell
Spatially defined Dsh–Lgl interaction contributes to directional tissue morphogenesis
Nicole Kaplan, Nicholas S. Tolwinski · 2010 · Journal of Cell Science
Tubulogenesis in a simple cell cord requires the formation of bi-apical cells through two discrete Par domains
Elsa Denker, Ivana Bočina, Di Jiang · 2013 · Development
Protein Scaffolds Control Localized Protein Kinase Cζ Activity
Irene S. Tobias, Alexandra C. Newton · 2016 · Journal of Biological Chemistry
How to make a static cytokinetic furrow out of traveling excitable waves
Andrew Boris Goryachev, Marcin Leda, Ann Louise Miller, George von Dassow, William M. Bement · 2016 · Small GTPases
DLG1 is an anchor for the E3 ligase MARCH2 at sites of cell–cell contact
Zhifang Cao, Alan S. Huett, Petric Kuballa, Cosmas C. Giallourakis, Ramnik J. Xavier · 2007 · Cellular Signalling
The Signaling Adaptor Gab1 Regulates Cell Polarity by Acting as a PAR Protein Scaffold
Ziqiang Yang, Bin Xue, Masataka Umitsu, Mitsuhiko Ikura, Senthil K. Muthuswamy, Benjamin G. Neel · 2012 · Molecular Cell
Two‐photon imaging of effector T‐cell behavior: lessons from a tumor model
Lai Guan Ng, Paulus Mrass, Ichiko Kinjyo, Steven L. Reiner, Wolfgang Weninger · 2008 · Immunological Reviews
Structural Insights into the Intrinsic Self-Assembly of Par-3 N-Terminal Domain
Yan Zhang, Wenjuan Wang, Jia Chen, Kai Zhang, Feng Gao, Bingquan Gao, Shuai Zhang, Mingdong Dong, Flemming Besenbacher, Weimin Gong et al. · 2013 · Structure
The Interaction of mPar3 with the Ubiquitin Ligase Smurf2 Is Required for the Establishment of Neuronal Polarity
Jens Christian Schwamborn, Mohammad R. Khazaei, Andreas W. Püschel · 2007 · Journal of Biological Chemistry · Retracted
Strategies for cell shape control in tip‐growing cells
Otger Campàs, Enrique Rojas, Jacques Dumais, L. Mahadevan · 2012 · American Journal of Botany
On the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN
Marina Mapelli, Cayetano González · 2012 · Open Biology
GSK3β affects apical–basal polarity and cell–cell adhesion by regulating aPKC levels
Pamela F. Colosimo, Xiaoping Liu, Nicole Kaplan, Nicholas S. Tolwinski · 2009 · Developmental Dynamics
Arg Kinase Regulates Epithelial Cell Polarity by Targeting β1-Integrin and Small GTPase Pathways
Ran Li, Ann Marie Pendergast · 2011 · Current Biology
Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1–induced collective directional migration and angiogenic sprouting
Malika Oubaha, Michelle I. Lin, Yoran Margaron, Dominic Filion, Emily Price, Leonard Ira Zon, Jean‐François Côté, Jean‐Philippe Gratton · 2012 · Blood
Nucleotide exchange factor ECT2 regulates epithelial cell polarity
Xiu Fen Liu, Shigeo Ohno, Toru Miki · 2006 · Cellular Signalling
Establishment of cell polarity by afadin during the formation of embryoid bodies
Hitomi Komura, Hisakazu Ogita, Wataru Ikeda, Akira Mizoguchi, Jun Miyoshi, Yoshimi Takai · 2007 · Genes to Cells
Subtype-specific roles of phospholipase C-β via differential interactions with PDZ domain proteins
Jung Kuk Kim, Seyoung Lim, Jinho Kim, Sanguk Kim, Jae Ho Kim, Sung Ho Ryu, Pann‐Ghill Suh · 2010 · Advances in Enzyme Regulation
Zinc transporter 2 interacts with vacuolar ATPase and is required for polarization, vesicle acidification, and secretion in mammary epithelial cells
Sooyeon Lee, Olivia C. Rivera, Shannon L. Kelleher · 2017 · Journal of Biological Chemistry
Polarized Subcellular Localization of JAK/STAT Components Is Required for Efficient Signaling
Sol Sotillos, Maria Teresa Díaz-Meco, Jorge Moscat, James Castelli‐Gair Hombría · 2008 · Current Biology
Tight Junctions and the Intestinal Barrier
Thomas Y. Ma, James Melvin Anderson · 2006 · Elsevier eBooks
Loss of Partitioning-Defective-3/Isotype-Specific Interacting Protein (Par-3/ASIP) in the Elongating Spermatid of RA175 (IGSF4A/SynCAM)-Deficient Mice
Eriko Fujita, Yuko Tanabe, Tomonori Hirose, Michel Aurrand‐Lions, Tadashi Kasahara, Beat A. Imhof, Shigeo Ohno, Takashi Momoi · 2007 · American Journal Of Pathology
Cell polarity emerges at first cleavage in sea urchin embryos
Lea M. Alford, Michelle M. Ng, David R. Burgess · 2009 · Developmental Biology
Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3
Tomoko Izaki, Sachiko Kamakura, Motoyuki Kohjima, Hideki Sumimoto · 2006 · Biochemical and Biophysical Research Communications
The Regulation of the Hippo Pathway by Intercellular Junction Proteins
Usama Sharif Ahmad, Jutamas Uttagomol, Hong Wan · 2022 · Life
A Modifier Screen for Bazooka/PAR-3 Interacting Genes in the Drosophila Embryo Epithelium
Wei Shao, Johnny Wu, Jeyla Chen, Donghoon M. Lee, Alisa Tishkina, Tony Harris · 2010 · PLoS ONE
G-protein-activated phospholipase C-β, new partners for cell polarity proteins Par3 and Par6
Yi Cai, Lewis J. Stafford, Brad Allen Bryan, Dianne Mitchell, Mingyao Liu · 2005 · Oncogene