Parsing the Polarity Code

Tight junction proteins

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par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed

Guo, S., & Kemphues, K. J. (1995) · Cell · doi:10.1016/0092-8674(95)90082-9 · Cited by 1,113 · see citing works

Integrin-Mediated Activation of Cdc42 Controls Cell Polarity in Migrating Astrocytes through PKCζ

Etienne‐Manneville, S., & Hall, A. K. (2001) · Cell · doi:10.1016/s0092-8674(01)00471-8 · Cited by 1,025 · see citing works

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

Joberty, G., Petersen, C., Gao, L., & Macara, I. G. (2000) · Nature Cell Biology · doi:10.1038/35019573 · Cited by 928 · see citing works

Cooperative Regulation of Cell Polarity and Growth by Drosophila Tumor Suppressors

Bilder, D. H., Li, M., & Perrimon, N. (2000) · Science · doi:10.1126/science.289.5476.113 · Cited by 916 · see citing works

MARK, a Novel Family of Protein Kinases That Phosphorylate Microtubule-Associated Proteins and Trigger Microtubule Disruption

Drewes, G., Ebneth, A., Preuss, U., Mandelkow, E.-M., & Mandelkow, E. (1997) · Cell · doi:10.1016/s0092-8674(00)80208-1 · Cited by 878 · see citing works

Identification of genes required for cytoplasmic localization in early C. elegans embryos

Kemphues, K. J., Priess, J. R., Morton, D. G., & Cheng, N. N. (1988) · Cell · doi:10.1016/s0092-8674(88)80024-2 · Cited by 859 · see citing works

Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity

Etienne-Manneville, S., & Hall, A. (2003) · Nature · doi:10.1038/nature01423 · Cited by 835 · see citing works

A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

Lin, D., Edwards, A. S., Fawcett, J. P., Mbamalu, G., Scott, J. D., & Pawson, T. (2000) · Nature Cell Biology · doi:10.1038/35019582 · Cited by 743 · see citing works

Sticky Business

Pérez‐Moreno, M., Jamora, C., & Fuchs, E. V. (2003) · Cell · doi:10.1016/s0092-8674(03)00108-9 · Cited by 717 · see citing works

Localization of apical epithelial determinants by the basolateral PDZ protein Scribble

Bilder, D., & Perrimon, N. (2000) · Nature · doi:10.1038/35001108 · Cited by 716 · see citing works

Divergent Signals and Cytoskeletal Assemblies Regulate Self-Organizing Polarity in Neutrophils

Xu, J., Wang, F., Keymeulen, A. V., Herzmark, P., Straight, A. F., Kelly, K., Takuwa, Y., Sugimoto, N., Mitchison, T. J., & Bourne, H. R. (2003) · Cell · doi:10.1016/s0092-8674(03)00555-5 · Cited by 687 · see citing works

A Conserved Binding Motif Defines Numerous Candidate Target Proteins for Both Cdc42 and Rac GTPases

Burbelo, P. D., Drechsel, D. N., & Hall, A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.49.29071 · Cited by 617 · see citing works

Nectin and afadin: novel organizers of intercellular junctions

Takai, Y., & Nakanishi, H. (2002) · Journal of Cell Science · doi:10.1242/jcs.00167 · Cited by 602 · see citing works

Hippocampal Neuronal Polarity Specified by Spatially Localized mPar3/mPar6 and PI 3-Kinase Activity

Shi, S.-H., Jan, L. Y., & Jan, Y.-N. (2003) · Cell · doi:10.1016/s0092-8674(02)01249-7 · Cited by 600 · see citing works

Rac1 and Cdc42 Capture Microtubules through IQGAP1 and CLIP-170

Fukata, M., Watanabe, T., Noritake, J., Nakagawa, M., Yamaga, M., Kuroda, S., Matsuura, Y., Iwamatsu, A., Perez, F., & Kaibuchi, K. (2002) · Cell · doi:10.1016/s0092-8674(02)00800-0 · Cited by 600 · see citing works

mDia mediates Rho-regulated formation and orientation of stable microtubules

Palazzo, A. F., Cook, T. A., Alberts, A. S., & Gundersen, G. G. (2001) · Nature Cell Biology · doi:10.1038/35087035 · Cited by 582 · see citing works

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl

Betschinger, J., Mechtler, K., & Knoblich, J. A. (2003) · Nature · doi:10.1038/nature01486 · Cited by 567 · see citing works

Epithelial cell polarity and cell junctions in Drosophila.

Tepass, U., Tanentzapf, G., Ward, R. E., & Fehon, R. (2001) · Annual Review of Genetics · doi:10.1146/annurev.genet.35.102401.091415 · Cited by 554 · see citing works

Signal Transduction in Neuronal Migration

Wong, K., Ren, X.-R., Huang, Y.-Z., Xie, Y., Liu, G., Saito, H., Tang, H., Wen, L., Brady‐Kalnay, S. M., Mei, L., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00530-x · Cited by 550 · see citing works

Cdc42: An Essential Rho-Type GTPase Controlling Eukaryotic Cell Polarity

Johnson, D. I. (1999) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.63.1.54-105.1999 · Cited by 534 · see citing works

A Role for Cdc42 in Macrophage Chemotaxis

Allen, W. E., Zicha, D., Ridley, A. J., & Jones, G. E. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.141.5.1147 · Cited by 528 · see citing works

An Atypical PKC Directly Associates and Colocalizes at the Epithelial Tight Junction with ASIP, a Mammalian Homologue of Caenorhabditis elegans Polarity Protein PAR-3

Izumi, Y., Hirose, T., Tamai, Y., Hirai, S.-I., Nagashima, Y., Fujimoto, T., Tabuse, Y., Kemphues, K. J., & Ohno, S. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.143.1.95 · Cited by 505 · see citing works

Direct interaction of two polarity complexes implicated in epithelial tight junction assembly

Hurd, T. W., Gao, L., Roh, M. H., Macara, I. G., & Margolis, B. L. (2003) · Nature Cell Biology · doi:10.1038/ncb923 · Cited by 487 · see citing works

CLASPs Are CLIP-115 and -170 Associating Proteins Involved in the Regional Regulation of Microtubule Dynamics in Motile Fibroblasts

Akhmanova, A. S., Hoogenraad, C. C., Drabek, K., Stepanova, T., Dortland, B. R., Verkerk, T., Vermeulen, W., Burgering, B. M. T., Zeeuw, C. I. D., Grosveld, F. G., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00288-4 · Cited by 481 · see citing works

Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils

Wang, F., Herzmark, P., Weiner, O. D., Srinivasan, S., Servant, G., & Bourne, H. R. (2002) · Nature Cell Biology · doi:10.1038/ncb810 · Cited by 471 · see citing works

Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts

Wodarz, A., Ramrath, A., Kuchinke, U., & Knust, E. (1999) · Nature · doi:10.1038/990128 · Cited by 451 · see citing works

Atypical Protein Kinase C Is Involved in the Evolutionarily Conserved Par Protein Complex and Plays a Critical Role in Establishing Epithelia-Specific Junctional Structures

Suzuki, A., Yamanaka, T., Hirose, T., Manabe, N., Mizuno, K., Shimizu, M., Akimoto, K., Izumi, Y., Ohnishi, T., & Ohno, S. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.6.1183 · Cited by 441 · see citing works

Integrated activity of PDZ protein complexes regulates epithelial polarity

Bilder, D., Schober, M., & Perrimon, N. (2003) · Nature Cell Biology · doi:10.1038/ncb897 · Cited by 435 · see citing works

Asymmetrically distributed PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos

Etemad-Moghadam, B., Guo, S., & Kemphues, K. J. (1995) · Cell · doi:10.1016/0092-8674(95)90187-6 · Cited by 427 · see citing works

DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila

Petronczki, M. P., & Knoblich, J. A. (2000) · Nature Cell Biology · doi:10.1038/35050550 · Cited by 419 · see citing works

Intercellular junctions and cellular polarity: the PAR–aPKC complex, a conserved core cassette playing fundamental roles in cell polarity

Ohno, S. (2001) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(00)00264-7 · Cited by 418 · see citing works

Drosophila PAR-1 and 14-3-3 Inhibit Bazooka/PAR-3 to Establish Complementary Cortical Domains in Polarized Cells

Benton, R., & Johnston, D. S. (2003) · Cell · doi:10.1016/s0092-8674(03)00938-3 · Cited by 410 · see citing works

CLIP-170 Highlights Growing Microtubule Ends In Vivo

Perez, F., Diamantopoulos, G. S., Stalder, R., & Kreis, T. E. (1999) · Cell · doi:10.1016/s0092-8674(00)80656-x · Cited by 397 · see citing works

armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila.

Müller, H. A., & Wieschaus, E. (1996) · The Journal of cell biology · doi:10.1083/jcb.134.1.149 · Cited by 384 · see citing works

Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts

Schöber, M., Schaefer, M., & Knoblich, J. A. (1999) · Nature · doi:10.1038/990135 · Cited by 383 · see citing works

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42.

Stowers, L., Yelon, D. L., Berg, L. J., & Chant, J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.11.5027 · Cited by 381 · see citing works

Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans

Tabuse, Y., Izumi, Y., Piano, F., Kemphues, K. J., Miwa, J., & Ohno, S. (1998) · Development · doi:10.1242/dev.125.18.3607 · Cited by 376 · see citing works

Directional Sensing Requires Gβγ-Mediated PAK1 and PIXα-Dependent Activation of Cdc42

Li, Z. A., Hannigan, M. O., Mo, Z., Liu, B., Lü, W., Wu, Y., Smrcka, A. V., Wu, G., Li, L., Liu, M., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00559-2 · Cited by 373 · see citing works

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl

Plant, P. J., Fawcett, J. P., Lin, D. C. C., Holdorf, A. D., Binns, K. L., Kulkarni, S., & Pawson, T. J. (2003) · Nature Cell Biology · doi:10.1038/ncb948 · Cited by 372 · see citing works

Analysis of partner of inscuteable, a Novel Player of Drosophila Asymmetric Divisions, Reveals Two Distinct Steps in Inscuteable Apical Localization

Yu, F., Morin, X., Cai, Y., Yang, X., & Chia, W. N. (2000) · Cell · doi:10.1016/s0092-8674(00)80676-5 · Cited by 370 · see citing works

Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization

Tanentzapf, G., & Tepass, U. (2003) · Nature Cell Biology · doi:10.1038/ncb896 · Cited by 367 · see citing works

Claudin-based barrier in simple and stratified cellular sheets

Tsukita, S., & Furuse, M. (2002) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(02)00362-9 · Cited by 363 · see citing works

Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity

Yamanaka, T., Horikoshi, Y., Sugiyama, Y., Ishiyama, C., Suzuki, A., Hirose, T., Iwamatsu, A., Shinohara, A., & Ohno, S. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00244-6 · Cited by 359 · see citing works

The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost

Roh, M. H., Makarova, O. V., Liu, C.-J., Shin, K., Lee, S., Laurinec, S., Goyal, M., Wiggins, R. C., & Margolis, B. L. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200109010 · Cited by 356 · see citing works

Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization

Palazzo, A. F., Joseph, H. L., Chen, Y., Dujardin, D., Alberts, A. S., Pfister, K. K., Vallee, R. B., & Gundersen, G. G. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00475-4 · Cited by 339 · see citing works

Temporal and Spatial Regulation of Chemotaxis

Iijima, M., Huang, Y. E., & Devreotes, P. N. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00292-7 · Cited by 338 · see citing works

A protein complex containing Inscuteable and the Gα-binding protein Pins orients asymmetric cell divisions in Drosophila

Schaefer, M., Shevchenko, A., Shevchenko, A., & Knoblich, J. A. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00401-2 · Cited by 337 · see citing works

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

Ohshiro, T., Yagami, T., Zhang, C., & Matsuzaki, F. (2000) · Nature · doi:10.1038/35046087 · Cited by 333 · see citing works

Heterotrimeric G Proteins Direct Two Modes of Asymmetric Cell Division in the Drosophila Nervous System

Schaefer, M., Petronczki, M. P., Dorner, D., Forte, M. A., & Knoblich, J. A. (2001) · Cell · doi:10.1016/s0092-8674(01)00521-9 · Cited by 323 · see citing works

PAR‐6 regulates aPKC activity in a novel way and mediates cell‐cell contact‐induced formation of the epithelial junctional complex

Yamanaka, T., Horikoshi, Y., Suzuki, A., Sugiyama, Y., Kitamura, K., Maniwa, R., Nagai, Y., Yamashita, A., Hirose, T., Ishikawa, H., et al. (2001) · Genes to Cells · doi:10.1046/j.1365-2443.2001.00453.x · Cited by 306 · see citing works

A role for Drosophila LKB1 in anterior–posterior axis formation and epithelial polarity

Martin, S. G., & Johnston, D. S. (2003) · Nature · doi:10.1038/nature01296 · Cited by 293 · see citing works

PAR-6 is a conserved PDZ domain-containing protein that colocalizes with PAR-3 in Caenorhabditis elegans embryos

Hung, T.-J., & Kemphues, K. J. (1999) · Development · doi:10.1242/dev.126.1.127 · Cited by 285 · see citing works

Translation of Polarity Cues into Asymmetric Spindle Positioning in Caenorhabditis elegans Embryos

Colombo, K., Grill, S. W., Kimple, R. J., Willard, F. S., Siderovski, D. P., & Gönczy, P. (2003) · Science · doi:10.1126/science.1084146 · Cited by 285 · see citing works

Positional cloning of heart and soul reveals multiple roles for PKCλ in zebrafish organogenesis

Horne‐Badovinac, S., Lin, D., Waldron, S., Schwarz, M., Mbamalu, G., Pawson, T. J., Jan, Y. N., Stainier, D. Y. R., & Abdelilah‐Seyfried, S. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00458-4 · Cited by 283 · see citing works

Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases

Cuenca, A. A., Schetter, A. J., Aceto, D., Kemphues, K. J., & Seydoux, G. (2003) · Development · doi:10.1242/dev.00284 · Cited by 281 · see citing works

Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity

Bachmann, A., Schneider, M., Theilenberg, E., Grawe, F., & Knust, E. (2001) · Nature · doi:10.1038/414638a · Cited by 279 · see citing works

A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCζ signaling and cell transformation

Qiu, R., Abo, A., & Martin, G. S. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00535-2 · Cited by 276 · see citing works

A non-muscle myosin required for embryonic polarity in Caenorhabditis elegans

Guo, S., & Kemphues, K. J. (1996) · Nature · doi:10.1038/382455a0 · Cited by 264 · see citing works

Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorhabditis elegans embryos

Gotta, M., & Ahringer, J. (2001) · Nature Cell Biology · doi:10.1038/35060092 · Cited by 264 · see citing works

A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization

Du, Q., Stukenberg, P. T., & Macara, I. G. (2001) · Nature Cell Biology · doi:10.1038/ncb1201-1069 · Cited by 262 · see citing works

PARsing Embryonic Polarity

Kemphues, K. J. (2000) · Cell · doi:10.1016/s0092-8674(00)80844-2 · Cited by 251 · see citing works

Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits

Kimple, R. J., Kimple, M. E., Betts, L., Sondek, J., & Siderovski, D. P. (2002) · Nature · doi:10.1038/416878a · Cited by 243 · see citing works

LIS1, CLIP-170's Key to the Dynein/Dynactin Pathway

Coquelle, F. M., Caspi, M., Cordelières, F. P., Dompierre, J., Dujardin, D., Koifman, C., Martin, P., Hoogenraad, C. C., Akhmanova, A. S., Galjart, N., et al. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.9.3089-3102.2002 · Cited by 240 · see citing works

Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts

Hong, Y., Stronach, B. E., Perrimon, N., Jan, L. Y., & Jan, Y. N. (2001) · Nature · doi:10.1038/414634a · Cited by 239 · see citing works

Asymmetrically Distributed C. elegans Homologs of AGS3/PINS Control Spindle Position in the Early Embryo

Gotta, M., Yan, D., Peterson, Y. K., Lanier, S. M., & Ahringer, J. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00371-3 · Cited by 239 · see citing works

The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry

Watts, J. L., Morton, D. G., Bestman, J. E., & Kemphues, K. J. (2000) · Development · doi:10.1242/dev.127.7.1467 · Cited by 236 · see citing works

A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C. elegansPreprint

Srinivasan, D. G., Fisk, R. M., Xu, H., & van den Heuvel, S. (2003) · Genes & Development · doi:10.1101/gad.1081203 · Cited by 231 · see citing works

CDC-42 controls early cell polarity and spindle orientation in C. elegans

Gotta, M., Abraham, M. C., & Ahringer, J. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00142-7 · Cited by 225 · see citing works

The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells

Roh, M. H., Fan, S., Liu, C., & Margolis, B. L. (2003) · Journal of Cell Science · doi:10.1242/jcs.00500 · Cited by 220 · see citing works

Regulated protein–protein interaction between aPKC and PAR‐3 plays an essential role in the polarization of epithelial cells

Tamai-Nagai, Y., Mizuno, K., Hirose, T., Suzuki, A., & Ohno, S. (2002) · Genes to Cells · doi:10.1046/j.1365-2443.2002.00590.x · Cited by 192 · see citing works

Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1)

Makarova, O., Roh, M. H., Liu, C., Laurinec, S., & Margolis, B. L. (2003) · Gene · doi:10.1016/s0378111902010843 · Cited by 190 · see citing works

Assembly of Epithelial Tight Junctions Is Negatively Regulated by Par6

Gao, L., Joberty, G., & Macara, I. G. (2002) · Current Biology · doi:10.1016/s0960-9822(01)00663-7 · Cited by 188 · see citing works

Mammalian Homolog of Drosophila Tumor Suppressor Lethal (2) Giant Larvae Interacts with Basolateral Exocytic Machinery in Madin-Darby Canine Kidney Cells

Müsch, A., Cohen, D., Yeaman, C. A., Nelson, W. J., Rodriguez-Boulan, E. J., & Brennwald, P. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.01-10-0496 · Cited by 186 · see citing works

nagie oko, encoding a MAGUK-family protein, is essential for cellular patterning of the retina

Wei, X., & Malicki, J. J. (2002) · Nature Genetics · doi:10.1038/ng883 · Cited by 181 · see citing works

The Carboxyl Terminus of Zona Occludens-3 Binds and Recruits a Mammalian Homologue of Discs Lost to Tight Junctions

Roh, M. H., Liu, C., Laurinec, S., & Margolis, B. L. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201177200 · Cited by 181 · see citing works

Structure of Cdc42 in a complex with the GTPase‐binding domain of the cell polarity protein, Par6

Garrard, S. M., Capaldo, C., Gao, L., Rosen, M. K., Macara, I. G., & Tomchick, D. R. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg110 · Cited by 179 · see citing works

hINADl/PATJ, a Homolog of Discs Lost, Interacts with Crumbs and Localizes to Tight Junctions in Human Epithelial Cells

Lemmers, C., Médina, E., Delgrossi, M.-H., Michel, D., Arsanto, J., & Bivic, A. L. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202196200 · Cited by 173 · see citing works

Involvement of ASIP/PAR-3 in the promotion of epithelial tight junction formation

Hirose, T., Izumi, Y., Nagashima, Y., Tamai-Nagai, Y., Kurihara, H., Sakai, T., Suzuki, Y., Yamanaka, T., Suzuki, A., Mizuno, K., et al. (2002) · Journal of Cell Science · doi:10.1242/jcs.115.12.2485 · Cited by 162 · see citing works

Zonula adherens formation in Caenorhabditis elegans requires dlg-1, the homologue of the Drosophila gene discs large

Bossinger, O., Klebes, A., Segbert, C., Theres, C., & Knust, E. (2001) · Developmental Biology · doi:10.1006/dbio.2000.0113 · Cited by 161 · see citing works

CDC-42 regulates PAR protein localization and function to control cellular and embryonic polarity in C. elegans

Kay, A. J., & Hunter, C. P. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00141-5 · Cited by 159 · see citing works

A Conserved Oligomerization Domain in Drosophila Bazooka/PAR-3 Is Important for Apical Localization and Epithelial Polarity

Benton, R., & Johnston, D. S. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00508-6 · Cited by 157 · see citing works

Phosphorylation-Dependent Binding of 14-3-3 to the Polarity Protein Par3 Regulates Cell Polarity in Mammalian Epithelia

Hurd, T. W., Fan, S., Liu, C.-J., Kweon, H. K., Håkansson, K., & Margolis, B. L. (2003) · Current Biology · doi:10.1016/j.cub.2003.11.020 · Cited by 154 · see citing works

The Caenorhabditis elegans par-5 Gene Encodes a 14-3-3 Protein Required for Cellular Asymmetry in the Early Embryo

Morton, D. G., Shakes, D. C., Nugent, S. L., Dichoso, D., Wang, W., Golden, A., & Kemphues, K. J. (2002) · Developmental Biology · doi:10.1006/dbio.2001.0489 · Cited by 152 · see citing works

The mammalian homologue of the <i>Caenorhabditis elegans</i> polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1

Johansson, A.-S., Driessens, M., & Aspenström, P. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.18.3267 · Cited by 146 · see citing works

LGN Blocks the Ability of NuMA to Bind and Stabilize Microtubules

Du, Q., Taylor, L. J., Compton, D. A., & Macara, I. G. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01298-8 · Cited by 145 · see citing works

Selective Interaction of AGS3 with G-proteins and the Influence of AGS3 on the Activation State of G-proteins

Bernard, M. L., Peterson, Y. K., Chung, P., Jourdan, J., & Lanier, S. M. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m005291200 · Cited by 145 · see citing works

Asymmetric cell division in the Drosophila nrevous system

Jan, Y. N., & Jan, L. Y. (2001) · Nature reviews. Neuroscience · doi:10.1038/35097516 · Cited by 134 · see citing works

Cdc42-dependent Modulation of Tight Junctions and Membrane Protein Traffic in Polarized Madin-Darby Canine Kidney Cells

Rojas, R., Ruiz, W. G., Leung, S.-M., Jou, T., & Apodaca, G. L. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.8.2257 · Cited by 133 · see citing works

Self-association of PAR-3-mediated by the Conserved N-terminal Domain Contributes to the Development of Epithelial Tight Junctions

Mizuno, K., Suzuki, A., Hirose, T., Kitamura, K., Kutsuzawa, K., Futaki, M., Amano, Y., & Ohno, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303593200 · Cited by 131 · see citing works

LKB1 (XEEK1) regulates Wnt signalling in vertebrate development

Ossipova, O., Bardeesy, N. M., DePinho, R. A., & Green, J. B. A. (2003) · Nature Cell Biology · doi:10.1038/ncb1048 · Cited by 130 · see citing works

Cell Polarity and the Cytoskeleton in theCaenorhabditis ElegansZygote

Schneider, S., & Bowerman, B. A. (2003) · Annual Review of Genetics · doi:10.1146/annurev.genet.37.110801.142443 · Cited by 129 · see citing works

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The NF2 Tumor Suppressor, Merlin, Regulates Epidermal Development through the Establishment of a Junctional Polarity Complex

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High-Glucose Inhibits Human Fibroblast Cell Migration in Wound Healing via Repression of bFGF-Regulating JNK Phosphorylation

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The PAR-6 Polarity Protein Regulates Dendritic Spine Morphogenesis through p190 RhoGAP and the Rho GTPase

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LIM Kinase-mediated Cofilin Phosphorylation during Mitosis Is Required for Precise Spindle Positioning

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