Regulation of the INK4b–ARF–INK4a tumour suppressor locus: all for one or one for all

Gil, Jesús, Peters, Gordon·2006·Nature Reviews Molecular Cell Biology

DOI 10.1038/nrm1987

Cited by (845)

Items 501–600 of 845

Association between 9p21 Genomic Markers and Ischemic Stroke Risk: Evidence Based on 21 Studies
Xiaoqing Ni, Jiawei Zhang · 2014 · PLoS ONE
Prognostic significance of the expression levels of the p16, p15, and p14 genes in dogs with high-grade lymphoma
Aki Fujiwara‐Igarashi, Yuko Goto‐Koshino, Masahiko Sato, Shingo Maeda, Hirotaka Igarashi, Masashi Takahashi, Yasuhito Fujino, Koichi Ohno, Hajime Tsujimoto · 2013 · The Veterinary Journal
Glypican-1 Stimulates Skp2 Autoinduction Loop and G1/S Transition in Endothelial Cells
Dianhua Qiao, Kristy K. Meyer, Andreas Friedl · 2011 · Journal of Biological Chemistry · Retracted
Sumoylation in Cellular Senescence and Aging
Lili Gong, Qian Sun, Di Li · 2017 · Current Molecular Medicine
Expression and regulation of long noncoding RNAs during the osteogenic differentiation of periodontal ligament stem cells in the inflammatory microenvironment
Qingbin Zhang, Li Chen, Shiman Cui, Yán Li, Qi Zhao, Wei Cao, Shixiang Lai, Sanjun Yin, Zhixiang Zuo, Jian Min Ren · 2017 · Scientific Reports
Expression of the p16INK4A/Cdkn2a Gene Is Prevalently Downregulated in Human Pheochromocytoma Tumor Specimens
Peter Muscarella, Mark Bloomston, Alexander Brewer, Anjali Mahajan, Wendy L. Frankel, Edwin Christopher Ellison, William Blair Farrar, Christopher M. Weghorst, Junan Li · 2008 · Gene Expression
TRIM28/KAP1 regulates senescence
Joana Santos, Jesús Gil · 2014 · Immunology Letters
Stem cell ageing: does it happen and can we intervene?
Ilaria Bellantuono, W. Nicol Keith · 2007 · Expert Reviews in Molecular Medicine
The functional role of cellular senescence during vascular calcification in chronic kidney disease
Yaping Fang, Yu Zhao, Jiayi Huang, Xin Yang, Yan Liu, Xiaoliang Zhang · 2024 · Frontiers in Endocrinology
T cell proliferation and adaptive immune responses are critically regulated by protein phosphatase 4
Fang‐Hsuean Liao, Wan‐Yi Hsiao, Yu‐Chun Lin, Yi-Chiao Chan, Ching‐Yu Huang · 2016 · Cell Cycle
5-aza-2′-deoxycytidine Inhibits the Proliferation of Lung Fibroblasts in Neonatal Rats Exposed to Hyperoxia
Shimeng Zhao, Meiling Cao, Hongmin Wu, Yu Hu, Xindong Xue · 2016 · Pediatrics & Neonatology
A distant, cis-acting enhancer drives induction of Arf by Tgfβ in the developing eye
Yanbin Zheng, Caitlin C. Devitt, Jing Liu, Jie Mei, Stephen X. Skapek · 2013 · Developmental Biology
Cellular Senescence: A Bridge Between Diabetes and Microangiopathy
Jiahui Liu, Buyu Guo, Qianqian Liu, Guomao Zhu, Yaqi Wang, Na Wang, Yichen Yang, Songbo Fu · 2024 · Biomolecules
Loss of p16: A Bouncer of the Immunological Surveillance?
Kelly E. Leon, Naveen Kumar Tangudu, Katherine M. Aird, Raquel Buj · 2021 · Life
JmjC‐domain containing histone demethylase 1B‐mediated p15Ink4b suppression promotes the proliferation of leukemic progenitor cells through modulation of cell cycle progression in acute myeloid leukemia
Satoki Nakamura, Lin Tan, Yasuyuki Nagata, Tomonari Takemura, Aya Asahina, Daisuke Yokota, Tomohiro Yagyu, Kiyoshi Shibata, Shinya Fujisawa, Kazunori Ohnishi · 2011 · Molecular Carcinogenesis
Hypermethylation of P 15 , P 16 , and E-cadherin genes in ovarian cancer
Said Salama Moselhy, Taha Kumosani, IH Kamal, J. Jalal, Hassan S Abdul Jabaar, Ashraf Dalol · 2013 · Toxicology and Industrial Health
La sénescence cellulaire
Jean‐Marc Brondello, Alexandre Prieur, Didier Philipot, Jean-Marc Lemaı̂tre, Guy Lenaers, Jacques Piette, Vjekoslav Dulić · 2012 · médecine/sciences
Long non-coding RNAs in prostate cancer: Biological and clinical implications
Rajdeep Das, Felix Yi-Chung Feng, Luke A. Selth · 2018 · Molecular and Cellular Endocrinology
Genes and pathways involved in senescence bypass identified by functional genetic screens
Eugenia Roupakia, Georgios S. Markopoulos, Evangelos Kolettas · 2021 · Mechanisms of Ageing and Development
HCV infection, IFN response and the coding and non-coding host cell genome
Elena Carnero, Puri Fortes · 2015 · Virus Research
Implication of p53-dependent cellular senescence related gene, TARSH in tumor suppression
Takeshi Wakoh, Natsuko Uekawa, Kunihiko Terauchi, Masataka Sugimoto, Akihito Ishigami, Junichi Shimada, Mitsuo Maruyama · 2009 · Biochemical and Biophysical Research Communications
SUMOylation, a multifaceted regulatory mechanism in the pancreatic beta cells
Na Li, Shu Zhang, Fei Xiong, Decio Laks Eizirik, Cong‐Yi Wang · 2020 · Seminars in Cell and Developmental Biology
Clinical Significance of P16 Gene Methylation in Lung Cancer
Yanjun Li, Tingting Zhang, Hui Zhang, Xiangdong Wang, Xiaozhuan Liu, Qihong Huang, Li Li · 2020 · Advances in experimental medicine and biology
LncRNAs as Regulators of Atherosclerotic Plaque Stability
Aleksa Petković, Sanja Erceg, Jelena Munjas, Ana Ninić, Sandra S. Vladimirov, Aleksandar Davidović, Luka Vukmirović, Marko Milanov, Dane Cvijanović, Tijana Mitić et al. · 2023 · Cells
Plant-Derived Epi-Nutraceuticals as Potential Broad-Spectrum Anti-Viral Agents
Rosita Gabbianelli, Ehud Shahar, Gaia de Simone, Chiara Rucci, Laura Bordoni, Giulia Feliziani, Fanrui Zhao, Marta Ferrati, Filippo Maggi, Eleonora Spinozzi et al. · 2023 · Nutrients
Bone Marrow p16INK4a-Deficiency Does Not Modulate Obesity, Glucose Homeostasis or Atherosclerosis Development
Kristiaan Wouters, Céline Cudejko, Marion J. Gijbels, Lucı́a Fuentes, Kadiombo Bantubungi, Jonathan Vanhoutte, Rébecca Dièvart, Charlotte Paquet, Emmanuel Bouchaert, Sarah Anissa Hannou et al. · 2012 · PLoS ONE
Higher incidence of death in multi-vessel coronary artery disease patients associated with polymorphisms in chromosome 9p21
Luciana Gioli‐Pereira, Paulo Caleb Júnior Lima Santos, Noely Evangelista Ferreira, Whady Armindo Hueb, José Eduardo Krieger, Alexandre C. Pereira · 2012 · BMC Cardiovascular Disorders
p19INK4d is involved in the cellular senescence mechanism contributing to heterochromatin formation
Silvina V. Sonzogni, María Florencia Ogara, Laura M. Belluscio, D. Castillo, María Élida Scassa, Eduardo Tomás Cánepa · 2014 · Biochimica et Biophysica Acta (BBA) - General Subjects
Knockout of Canopy 2 activates p16INK4a pathway to impair cardiac repair
Wenjuan Yin, Jian Guo, Chongyu Zhang, Faisal J. Alibhai, Shuhong Li, Filio Billia, Jun Wu, Terrence M. Yau, Richard D. Weisel, Ren‐Ke Li · 2019 · Journal of Molecular and Cellular Cardiology
From General Aberrant Alternative Splicing in Cancers and Its Therapeutic Application to the Discovery of an Oncogenic DMTF1 Isoform
Na Tian, Jialiang Li, Jinming Shi, Guangchao Sui · 2017 · International Journal of Molecular Sciences
Melatonin ameliorates glyphosate- and hard water-induced renal tubular epithelial cell senescence via PINK1-Parkin-dependent mitophagy
Lin Zhang, Fan Ding, Xuan Wu, Ruojing Wang, Yi Wan, Jianying Hu, Xiaoyan Zhang, Qing Wu · 2023 · Ecotoxicology and Environmental Safety
Senescence in cancer: Hallmarks, paradoxes, and therapeutic promise
Clemens Hinterleitner, Hailey V. Goldberg, Domhnall McHugh, Valentin J.A. Barthet, Aveline A. Filliol, Scott W. Lowe · 2026 · Cell
p53 as the main traffic controller of the cell signaling network
Sinto Sebastian · 2010 · Frontiers in bioscience
CDK4/6 Inhibitors in Pancreatobiliary Cancers: Opportunities and Challenges
Tatjana Arsenijevic, Katia Coulonval, Eric Raspé, Anne Demols, Pierre P. Roger, Jean‐Luc Van Laethem · 2023 · Cancers
Signaling Pathways in Cancer
D. Kalderon · 2008 · Humana Press eBooks
RUVBL2 is a novel repressor of ARF transcription
Chongwei Xie, Wenyu Wang, Fan Yang, Mian Wu, Yide Mei · 2012 · FEBS Letters
The landscape of DNA methylation in hepatocellular carcinoma
Yongfa Zheng, Xiaojie Lu, Xiaoyu Zhang, Bu‐Gao Guan · 2018 · Journal of Cellular Physiology
Oncoepigenomics: Making histone lysine methylation count
Daniel DeCarlo, Matthew Kyle Hadden · 2012 · European Journal of Medicinal Chemistry
Redistribution of EZH2 promotes malignant phenotypes by rewiring developmental programmes
Thomas Mortimer, Elanor N. Wainwright, Harshil Patel, Bernard M. Siow, Zane Jaunmuktane, Sebastian Brandner, Paola Scaffidi · 2019 · EMBO Reports
In VivoRegulation of E2F1 by Polycomb Group Genes inDrosophila
Jun‐Yuan Ji, Wayne O. Miles, Michael Korenjak, Yani Zheng, Nicholas J. Dyson · 2012 · G3 Genes Genomes Genetics
A Novel Approach for Determining Cancer Genomic Breakpoints in the Presence of Normal DNA
Yu‐Tsueng Liu, Dennis Anthony Carson · 2007 · PLoS ONE
B cell senescence promotes age‐related changes in oral microbiota
Hiroya Mizuno, Shimpei Kawamoto, Ken Uemura, Jeong Hoon Park, Nozomi Hori, Yumiko Okumura, Yusuke Konishi, Eiji Hara · 2024 · Aging Cell
Effects of the p16/cyclin D1/CDK4/Rb/E2F1 pathway on aberrant lung fibroblast proliferation in neonatal rats exposed to hyperoxia
Shimeng Zhao, Zhiguang Chen, Shuang Han, Hongmin Wu · 2021 · Experimental and Therapeutic Medicine
The role of BMI1 in endometrial cancer and other cancers
Yiting Zhao, Weili Yang, Kaifeng Zheng, Jun Chen, Xiaofeng Jin · 2022 · Gene
Increased gene dosage of the Ink4/Arf locus does not attenuate atherosclerosis development in hypercholesterolaemic mice
José J. Fuster, Pedro Molina-Sánchez, David Jovani-Sales, Ángela Vinué, Manuel Serrano, Vicente Andrés · 2011 · Atherosclerosis
Downregulated Expression of Chromobox Homolog 7 in Hepatocellular Carcinoma
Xiaonian Zhu, Mingqun Qin, Cong Li, Wen Zeng, Chunhua Bei, Chao Tan, Ying Zhang, Wenxiang Shi, Juan Kong, Yuanyuan Fu et al. · 2019 · Genetic Testing and Molecular Biomarkers
Quantitative analysis of CDKN2A methylation, mRNA, and p16INK4a protein expression in children and adolescents with Burkitt lymphoma: Biological and clinical implications
Marcela Cristina Robaina, Roberta Soares Faccion, Viviane Oliveira Arruda, Lídia Maria Magalhães de Rezende, Gisele M. Vasconcelos, Alexandre Gustavo Apa, Carlos E. Bacchi, Claudete Esteves Klumb · 2014 · Leukemia Research
Single nucleotide polymorphism rs1333049 on chromosome 9p21.3 is associated with Alzheimer's disease in Han Chinese
Jin‐Tai Yu, Yu Pu Yang, Wei Zhang, Zhong‐Chen Wu, Yang Li, Na Zhang, Lan Tan · 2010 · Clinica Chimica Acta
Non-coding RNA ANRIL and the number of plexiform neurofibromas in patients with NF1microdeletions
Tanja Mußotter, Lan Kluwe, Josef Högel, Rosa Nguyen, D.N. Cooper, Victor‐Felix Mautner, Hildegard Kehrer‐Sawatzki · 2012 · BMC Medical Genetics
Regulation of proliferation in developing human tooth germs by MSX homeodomain proteins and cyclin-dependent kinase inhibitor p19 INK4d
Darko Kero, Katarina Vukojević, Petra Stazić, Danijela Šundov, Snježana Mardešić, Mirna Saraga‐Babić · 2017 · Organogenesis
A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis
Paul Krimpenfort, Margriet Snoek, Jan-Paul Lambooij, Ji‐Ying Song, Robin H. van der Weide, Rajith Bhaskaran, Hans Teunissen, David J. Adams, Elzo de Wit, Anton J. M. Berns · 2019 · Nature Communications
SIRT6-PAI-1 axis is a promising therapeutic target in aging-related bone metabolic disruption
Alkebaier Aobulikasimu, Tao Liu, Jinying Piao, Shingo Sato, Hiroki Ochi, Atsushi Okawa, Kunikazu Tsuji, Yoshinori Asou · 2023 · Scientific Reports
Telomere dysfunction and cell cycle checkpoints in hematopoietic stem cell aging
Zhenyu Ju, Junling Zhang, Yingdai Gao, Tao Cheng · 2011 · International Journal of Hematology
Mechanism of cisplatin resistance in human urothelial carcinoma cells
Huimin Yu, Tsing-Cheng Wang · 2012 · Food and Chemical Toxicology
LncRNAs and Cardiovascular Disease
Elizabeth J. Hennessy · 2022 · Advances in experimental medicine and biology
Co-regulation of senescence-associated genes by oncogenic homeobox proteins and polycomb repressive complexes
Nadine Martin, Selina Raguz, Gopuraja Dharmalingam, Jesús Gil · 2013 · Cell Cycle
Paradoxical down-regulation of p16 mRNA with advancing age in Acute Myeloid Leukemia
Hendrik J.M. de Jonge, Carolien M. Woolthuis, Eveline S.J.M. de Bont, Gerwin A Huls · 2009 · Aging
The Yin-Yang of DNA Damage Response: Roles in Tumorigenesis and Cellular Senescence
Xiaoman Li, Hongde Xu, XU Chong-an, Meina Lin, Xiaoyu Song, Fei Yi, Yanling Feng, Kathleen A. Coughlan, William Cho, Sang Wun Kim et al. · 2013 · International Journal of Molecular Sciences
Evaluation of Prognostic Parameters to Identify Aggressive Penile Carcinomas
Jan Niklas Mink, Oybek Khalmurzaev, Alexey E. Pryalukhin, Carol Immanuel Geppert, Stefan Lohse, Kristof Bende, João Lobo, Rui Henrique, Hagen Loertzer, J. Steffens et al. · 2023 · Cancers
Activation of automethylated PRC2 by dimerization on chromatin
Paul Victor Sauer, Egor A. Pavlenko, Trinity Cookis, Linda C. Zirden, Juliane Renn, Ankush Singhal, Pascal Hunold, Michaela Nicole Hoehne, Olivia van Ray, Farnusch Kaschani et al. · 2024 · Molecular Cell
Pharmacological targeting of P300/CBP reveals EWS::FLI1-mediated senescence evasion in Ewing sarcoma
Erdong Wei, Ana Mitanoska, Quinn O'Brien, Kendall Porter, MacKenzie Molina, Haseeb Ahsan, Usuk Jung, Lauren J. Mills, Michael Kyba, Darko Bosnakovski · 2024 · Molecular Cancer
Simultaneous aberrations of single CDKN2A network components and a high Rb phosphorylation status can differentiate subgroups of primary cutaneous B-cell lymphomas
Kjell Matthias Kaune, Christine R. Neumann, Christian Hallermann, Florian Haller, Michael Peter Schön, Peter Middel · 2011 · Experimental Dermatology
Transcriptome analysis of signaling pathways targeted by Ellagic acid in hepatocellular carcinoma cells
Shuang Qiu, Zhong Chen, Bo Zhao, Guangyue Li, Jinhua Wang, Shah Jehan, Jialiang Li, Xudong Zhao, Dangdang Li, Guangchao Sui · 2021 · Biochimica et Biophysica Acta (BBA) - General Subjects
Evidence that P12, a specific variant of P16INK4A, plays a suppressive role in human pancreatic carcinogenesis
Ming Jye Poi, Thomas J. Knobloch, Chunhua Yuan, Ming‐Daw Tsai, Christopher M. Weghorst, Junan Li · 2013 · Biochemical and Biophysical Research Communications
Role of Enhancer of Zeste Homolog 2 Polycomb Protein and Its Significance in Tumor Progression and Cell Differentiation
Irene Marchesi, Luigi Bagell · 2013 · InTech eBooks
Novel Aspects in Acute Lymphoblastic Leukemia
Stefan H Faderl · 2011 · InTech eBooks
Detecting Senescence: Methods and Approaches
Elizabeth P. Crowe, Timothy Nacarelli, Alessandro Bitto, Chad A. Lerner, Christian Sell, Claudio A. Torres · 2014 · Methods in molecular biology
Menin Plays a Critical Role in the Regulation of the Antigen-Specific CD8+ T Cell Response upon Listeria Infection
Takeshi Yamada, Makoto Kanoh, Shogo Nabe, Toshiaki Yasuoka, Junpei Suzuki, Akira Matsumoto, Makoto Kuwahara, Saho Maruyama, Takuya Fujimoto, Ryo Sakisuka et al. · 2016 · The Journal of Immunology
Promoter methylation of RB1, P15, P16, and MGMT and their impact on the clinical course of pilocytic astrocytomas
Christoph Sippl, Steffi Urbschat, Yoo Kim, Sebastian Senger, Joachim Oertel, Ralf Ketter · 2017 · Oncology Letters
Significant association of SNP polymorphism in the tilapiaenhancer of polycomb homolog 1gene with salt tolerance
Xiao Hui Gu, Hao Lin, Jun Hong Xia · 2018 · Aquaculture Research
BMI1 Roles in Cancer Stem Cells and Its Association with MicroRNAs Dysregulation in Cancer: Emphasis on Colorectal Cancer
Mohammad Hasan Soheilifar, Abdolvahab Moshtaghian, Hamid Maadi, Fereshteh Izadi, Massoud Saidijam · 2018 · International Journal of Cancer Management
Translation of Cellular Senescence to Novel Therapeutics: Insights From Alternative Tools and Models
Nurcan Inci, Dilanur Kamali, Erdogan Oguzhan Akyildiz, Eda Tahir Turanlı, Perinur Bozaykut · 2022 · Frontiers in Aging
Novel insights on the positive correlation between sense and antisense pairs on gene expression
Subhadeep Das, Maria Paula Zea Rojas, Elizabeth J. Tran · 2024 · Wiley Interdisciplinary Reviews - RNA
CDK4/6 inhibitors for the treatment of advanced hormone receptor positive breast cancer and beyond: 2016 update
Ciara Catherine O'Sullivan · 2016 · Expert Opinion on Pharmacotherapy
Genetic Alteration Profiles and Clinicopathological Associations in Atypical Parathyroid Adenoma
Xinxin Mao, Yan Wu, Shuangni Yu, Jie Chen · 2021 · International Journal of Genomics
Cellular senescence and abdominal aortic aneurysm: From pathogenesis to therapeutics
Ding Wang, Xinyu Hao, Longyuan Jia, Yuchen Jing, Bo Jiang, Shijie Xin · 2022 · Frontiers in Cardiovascular Medicine
EGCG Prevents the Transcriptional Reprogramming of an Inflammatory and Immune-Suppressive Molecular Signature in Macrophage-like Differentiated Human HL60 Promyelocytic Leukemia Cells
Celia Kassouri, Sahily Rodriguez Torres, Narjara González Suárez, Stéphanie Duhamel, Borhane Annabi · 2022 · Cancers
Simultaneous Inactivation of the p16, p15 and p14 Genes Encoding Cyclin-Dependent Kinase Inhibitors in Canine T-Lymphoid Tumor Cells
Aki Fujiwara‐Igarashi, Yuko Goto‐Koshino, Hiroyuki Mochizuki, Shingo Maeda, Yasuhito Fujino, Koichi Ohno, Hajime Tsujimoto · 2013 · Journal of Veterinary Medical Science
hMTH1 is required for maintaining migration and invasion potential of human thyroid cancer cells
Katarzyna D. Arczewska, Anna Stachurska, Maria Wojewódzka, Kamila Karpińska, Marcin K. Kruszewski, Hilde Loge Nilsen, Barbara Czarnocka · 2018 · DNA repair
The Influence of Distinct Regulatory miRNAs of the p15/p16/RB1/E2F Pathway on the Clinical Progression of Glioblastoma Multiforme
Christoph Sippl, Fritz Teping, Ralf Ketter, Luisa Braun, Luisa M Tremmel, Walter Schulz‐Schaeffer, Joachim Oertel, Steffi Urbschat · 2019 · World Neurosurgery
β-elemene promotes the senescence of glioma cells through regulating YAP-CDK6 signaling.
Danlu Yang, Xingxing Xu, Xin Wang, Wenjin Feng, Xiya Shen, Jingjing Zhang, Huitao Liu, Changnan Xie, Qian Wu, Xuemeng Miao et al. · 2021 · PubMed Central
How to measure RNA expression in rare senescent cells expressing any specific protein such as p16Ink4a
Jessie C. Jeyapalan, John M. Sedivy · 2013 · Aging
Loss of the transcription repressor ZHX3 induces senescence-associated gene expression and mitochondrial-nucleolar activation
Tomoka Igata, Hiroshi Tanaka, Kan Etoh, Seonghyeon Hong, Naoki Tani, Tomoaki Koga, Mitsuyoshi Nakao · 2022 · PLoS ONE
To senesce or not to senesce: how primary human fibroblasts decide their cell fate after DNA damage
Gabriel Kollárovič, Maja Studencka‐Turski, Lyubomira Ivanova, Claudia Lauenstein, Kristina Heinze, Anastasiya Lapytsko, Soheil Rastgou Talemi, Ana Sofia Figueiredo, Jörg Schaber · 2016 · Aging
miRNA-26a expression influences the therapy response to carmustine wafer implantation in patients with glioblastoma multiforme
Christoph Sippl, Ralf Ketter, Luisa Braun, Fritz Teping, Louisa Schoeneberger, Yoo Jin Kim, Markus List, Arjang Nakhoda, Silke Wemmert, Joachim Oertel et al. · 2019 · Acta Neurochirurgica
Cellular senescence: Silent operator and therapeutic target in cancer
Deepika Ramu, Wei Shan Teoh, Jayshree L. Hirpara, Shazib Pervaiz · 2021 · IUBMB Life
Genetic diversity during the development of Barrett's oesophagus-associated adenocarcinoma: how, when and why?
Trevor A. Graham, Stuart A.C. McDonald · 2010 · Biochemical Society Transactions
Epigenetic Changes in Tumor Suppressor Genes, P15, P16, APC‐3 and E‐cadherin in Body Fluid
Meiling Chen, Julia Huei‐Mei Chang, Kun‐Tu Yeh, Ya‐Sian Chang, Jan‐Gowth Chang · 2007 · The Kaohsiung Journal of Medical Sciences
Regulation of CDKN2B expression by interaction of Arnt with Miz-1 - a basis for functional integration between the HIF and Myc gene regulatory pathways
Reidun Aesöy, Katarina Gradin, Kathrine Sivertsen Nordhus, Erling André Høivik, Jorge Lira Ruas, Lorenz Poellinger, Marit Bakke · 2014 · Molecular Cancer
Identification of De Novo Enhancers Activated by TGFβ to Drive Expression of CDKN2A and B in HeLa Cells
Yen‐Ting Liu, Lin Xu, Lynda B. Bennett, Jared C. Hooks, Jing Liu, Qinbo Zhou, Priscilla H. Liem, Yanbin Zheng, Stephen X. Skapek · 2019 · Molecular Cancer Research
Premature aging in chronic kidney disease: Decoding senescence biomarkers and therapeutic opportunities
Carlos Eduardo H. V. P. F. Braga, Jessyca Sousa de Brito, Marcia Maria Ribeiro, Karen Salve Coutinho‐Wolino, Bruna Regis, Bruna Calixto, Renata Cristina Bezerra Rodrigues, Angela Yee-Moon Wang, Peter Stenvinkel, Denise Mafra · 2025 · Biochimie
G1/S arrest: a key mechanism of cellular aging and replicative senescence
李向东, Xin Yan, Qi Chen, Sui Mai · 2026 · Biogerontology
Sustained activation of NF-κB through constitutively active IKKβ leads to senescence bypass in murine dermal fibroblasts
Masayuki Harada, Kanae Su-Harada, Takeshi Kimura, Koh Ono, Noboru Ashida · 2024 · Cell Cycle
Preclinical evaluation of CDK4 phosphorylation predicts high sensitivity of pleural mesotheliomas to CDK4 /6 inhibition
Sabine Paternot, Eric Raspé, Clément Meiller, Maxime Tarabichi, Jean‐Baptiste Assié, Frédérick Libert, Myriam Remmelink, Xavier Bisteau, Patrick Pauwels, Yuna Blum et al. · 2022 · Molecular Oncology
CDK4 phosphorylation status and rational use for combining CDK4/6 and BRAF/MEK inhibition in advanced thyroid carcinomas
Jaime Miguel Gomes Pita, Eric Raspé, Katia Coulonval, Myriam Decaussin‐Petrucci, Maxime Tarabichi, Geneviève Dom, Frédérick Libert, Ligia Craciun, Guy Andry, Laurence Wicquart et al. · 2023 · Frontiers in Endocrinology
Prognostic and predictive biomarkers in central nervous system tumours: the molecular state of play
Laveniya Satgunaseelan, Joanne S. Sy, Brindha Shivalingam, Hao‐Wen Sim, Kimberley L. Alexander, Michael E. Buckland · 2023 · Pathology
Tumor suppressor p16INK4A/Cdkn2a alterations in 7, 12‐dimethylbenz(a)anthracene (DMBA)‐induced hamster cheek pouch tumors
Junan Li, Blake M. Warner, Bruce C. Casto, Thomas J. Knobloch, Christopher M. Weghorst · 2008 · Molecular Carcinogenesis
Stemness of T cells and the hematopoietic stem cells: Fate, memory, niche, cytokines
Francesca B. Aiello, Laura Graciotti, Antonio Domenico Procopio, Jonathan R. Keller, Scott Kenneth Durum · 2013 · Cytokine & Growth Factor Reviews
Reprogramming of gastrointestinal cancer cells
Dyah Laksmi Dewi, Hideshi Ishii, Naotsugu Haraguchi, Shimpei Nishikawa, Yoshihiro Kano, Takahito Fukusumi, Katsuya Ohta, Susumu Miyazaki, Miyuki Ozaki, Daisuke Sakai et al. · 2011 · Cancer Science
Differential expression of cell-cycle regulatory proteins defines distinct classes of follicular lymphoma
Abdulmohsen Alhejaily, Brianne Wood, Cheryl J. Foster, Patricia L. Farmer, C. Blake Gilks, Julia A. Brettschneider, Andrew G. Day, Harriet E. Feilotter, Tara D. Baetz, David P. LeBrun · 2011 · Human Pathology