The second wave of synthetic biology: from modules to systems

Stochastic Gene Expression in a Single Cell

Elowitz, M. B., Levine, A. J., Siggia, E. D., & Swain, P. S. (2002) · Science · doi:10.1126/science.1070919 · Cited by 5,441

Stability and Complexity in Model Ecosystems

May, R. M. (2001) · Princeton University Press eBooks · doi:10.1515/9780691206912 · Cited by 5,229

A synthetic oscillatory network of transcriptional regulators

Elowitz, M., & Leibler, S. (2000) · Nature · doi:10.1038/35002125 · Cited by 4,812

Construction of a genetic toggle switch in Escherichia coli

Gardner, T. S., Cantor, C. R., & Collins, J. J. (2000) · Nature · doi:10.1038/35002131 · Cited by 4,310

STABILITY AND COMPLEXITY IN MODEL ECOSYSTEMS

Schoener, T. W., & May, R. M. (1974) · Evolution · doi:10.1111/j.1558-5646.1974.tb00784.x · Cited by 3,989

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

Ro, D.-K., Paradise, E. M., Ouellet, M., Fisher, K. J., Newman, K. L., Ndungu, J. M., Ho, K. A., Eachus, R. A., Ham, T. S., Kirby, J., et al. (2006) · Nature · doi:10.1038/nature04640 · Cited by 2,805

Stability and Complexity in Model Ecosystems.

Schoener, T. W., & May, R. M. (1974) · Evolution · doi:10.2307/2407184 · Cited by 1,757

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

Martin, V. J. J., Pitera, D. J., Withers, S. T., Newman, J. D., & Keasling, J. D. (2003) · Nature Biotechnology · doi:10.1038/nbt833 · Cited by 1,720

PEST sequences and regulation by proteolysis

Rechsteiner, M., & Rogers, S. W. (1996) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(96)10031-1 · Cited by 1,707

Noise in eukaryotic gene expression

Blake, W. J., Kærn, M., Cantor, C. R., & Collins, J. J. (2003) · Nature · doi:10.1038/nature01546 · Cited by 1,636

Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications

Clauer, P. R., Nou, A., Toth, T., Yu, Q., Chemla, Y., Boo, A., Yoon, K. S., & Voigt, C. A. (2026) · Chemical Reviews · doi:10.1021/acs.chemrev.4c00687 · Cited by 21

A Robust Molecular Network Motif for Period-Doubling Devices

Samaniego, C. C., & Franco, E. (2017) · ACS Synthetic Biology · doi:10.1021/acssynbio.7b00222 · Cited by 19

Synthetic Gene Circuits: Design, Implement, and Apply

Lezia, A., Miano, A., & Hasty, J. (2021) · Proceedings of the IEEE · doi:10.1109/jproc.2021.3134169 · Cited by 19

Describing complex design practices with a cross-domain framework: learning from Synthetic Biology and Swarm Robotics

Chen, C., & Crilly, N. (2016) · Research in Engineering Design · doi:10.1007/s00163-016-0219-2 · Cited by 19

Constructing de Novo H2O2 Signaling via Induced Protein Proximity

Zeng, G., Zhang, R., Xuan, W., Wang, W., & Liang, F. (2015) · ACS Chemical Biology · doi:10.1021/acschembio.5b00170 · Cited by 19

Characterization of a designed synthetic autotrophic–heterotrophic consortia for fixing CO 2 without light

Hu, J., Xue, Y., Li, J., Wang, L., Zhang, S., Wang, Y., & Gao, M. (2016) · RSC Advances · doi:10.1039/c6ra13118b · Cited by 19

Synthetic biology strategies towards the development of new bioinspired technologies for medical applications

Rodrigues, J. L., Ferreira, D., & Rodrigues, L. R. (2016) · Elsevier eBooks · doi:10.1016/b978-0-08-100741-9.00016-4 · Cited by 18

Application of Synthetic Biology to Regenerative Medicine

Cachat, É., & Davies, J. A. (2011) · Journal of Bioengineering and Biomedical Sciences · doi:10.4172/2155-9538.s2-003 · Cited by 19

ROC’n’Ribo: Characterizing a Riboswitching Expression System by Modeling Single-Cell Data

Schneider, C. M., Bronstein, L., Diemer, J., Koeppl, H., & Suess, B. (2017) · ACS Synthetic Biology · doi:10.1021/acssynbio.6b00322 · Cited by 19

An analytical approach to bistable biological circuit discrimination using real algebraic geometry

Siegal‐Gaskins, D., Franco, E., Zhou, T., & Murray, R. M. (2015) · Journal of The Royal Society Interface · doi:10.1098/rsif.2015.0288 · Cited by 19

Fluigi

Huang, H., & Densmore, D. M. (2014) · ACM Journal on Emerging Technologies in Computing Systems · doi:10.1145/2660773 · Cited by 17

Pathway engineering via quorum sensing and sRNA riboregulators—Interconnected networks and controllers

Carter, K. K., Valdés, J. J., & Bentley, W. E. (2011) · Metabolic Engineering · doi:10.1016/j.ymben.2011.11.006 · Cited by 18

Robust Approaches for Genetic Regulatory Network Modeling and Intervention: A review of recent advances

Pal, R., Bhattacharya, S., & Caglar, M. U. (2011) · IEEE Signal Processing Magazine · doi:10.1109/msp.2011.942818 · Cited by 18

Biobricks and Crocheted Coral: Dispatches from the Life Sciences in the Age of Fabrication

Roosth, S. (2013) · Science in Context · doi:10.1017/s0269889712000324 · Cited by 18

Microbial synthetic biology for human therapeutics

Jain, A., Bhatia, P., & Chugh, A. (2012) · Systems and Synthetic Biology · doi:10.1007/s11693-012-9092-0 · Cited by 18

Modular Design of a Synthetic Payload Delivery Device

Huh, J. H., Kittleson, J. T., Arkin, A. P., & Anderson, J. C. (2013) · ACS Synthetic Biology · doi:10.1021/sb300107h · Cited by 18

Genetic Design via Combinatorial Constraint Specification

Bhatia, S. P., Smanski, M. J., Voigt, C. A., & Densmore, D. M. (2017) · ACS Synthetic Biology · doi:10.1021/acssynbio.7b00154 · Cited by 18

Fe3O4@chitosan Microspheres Coating as Cytoprotective Exoskeletons for the Enhanced Production of Butyric Acid With Clostridium tyrobutyricum Under Acid Stress

Liu, T., Jiang, C., Zhu, L., Jiang, L., & Huang, H. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00449 · Cited by 17

Flapjack: Data Management and Analysis for Genetic Circuit Characterization

Feliú, G. Y., Gómez, B. E., Berrocal, V. C., Silva, M. M., Núñez, I., Matúte, T., Arce, A., Vidal, G., Vitalis, C., Dahlin, J., et al. (2020) · ACS Synthetic Biology · doi:10.1021/acssynbio.0c00554 · Cited by 18

Modularization of genetic elements promotes synthetic metabolic engineering

Qi, H., Li, B., Zhang, W., Liu, D., & Yuan, Y. (2015) · Biotechnology Advances · doi:10.1016/j.biotechadv.2015.04.002 · Cited by 18

Designing de novo: interdisciplinary debates in synthetic biology

Delgado, A. M., & Porcar, M. (2013) · Systems and Synthetic Biology · doi:10.1007/s11693-013-9106-6 · Cited by 18

Advances in microbial heterologous production of flavonoids

Du, F., Fangkai, Z., Feifei, C., Anming, W., Qiuyan, W., Xiaopu, Y., & Shuling, W. (2011) · African Journal of Microbiology Research · doi:10.5897/ajmr11.394 · Cited by 18

A Data-Driven Framework for Identifying Nonlinear Dynamic Models of Genetic Parts

Krishnanathan, K., Anderson, S., Billings, S. A., & Kadirkamanathan, V. (2012) · ACS Synthetic Biology · doi:10.1021/sb300009t · Cited by 19

Nonequilibrium Thermodynamics in Biochemical Systems and Its Application

Zhang, D., & Ouyang, Q. (2021) · Entropy · doi:10.3390/e23030271 · Cited by 17

Self-organized collective cell behaviors as design principles for synthetic developmental biology

Hartmann, J., & Mayor, R. (2022) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2022.04.009 · Cited by 17

Genetic Parts and Enabling Tools for Biocircuit Design

Buson, F. X., Gao, Y., & Wang, B. (2024) · ACS Synthetic Biology · doi:10.1021/acssynbio.3c00691 · Cited by 19

Modelling hematopoiesis in health and disease

Peixoto, D., Dingli, D., & Pacheco, J. M. (2010) · Mathematical and Computer Modelling · doi:10.1016/j.mcm.2010.04.013 · Cited by 17

Approaches to chemical synthetic biology

Chiarabelli, C., Stano, P., Anella, F., Carrara, P., & Luisi, P. L. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.01.014 · Cited by 17

Continuous computation in engineered gene circuits

Goñi‐Moreno, Á., & Amos, M. (2012) · Biosystems · doi:10.1016/j.biosystems.2012.02.001 · Cited by 17

Probing the Input–Output Behavior of Biochemical and Genetic Systems

Ang, J., Ingalls, B., & McMillen, D. R. (2010) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/b978-0-12-381270-4.00010-x · Cited by 17

2ab assembly: a methodology for automatable, high-throughput assembly of standard biological parts

Leguía, M., Brophy, J. A. N., Densmore, D. M., Asante, A., & Anderson, J. C. (2013) · Journal of Biological Engineering · doi:10.1186/1754-1611-7-2 · Cited by 17

Deciphering Combinatorial Genetics

Wong, A. S. L., Choi, G. C. G., & Lu, T. K. (2016) · Annual Review of Genetics · doi:10.1146/annurev-genet-120215-034902 · Cited by 17

CSDB_GT: a new curated database on glycosyltransferases

Egorova, K. S., & Toukach, F. V. (2016) · Glycobiology · doi:10.1093/glycob/cww137 · Cited by 17

Using Synthetic Biology to Understand the Evolution of Gene Expression

Bayer, T. S. (2010) · Current Biology · doi:10.1016/j.cub.2010.06.049 · Cited by 18

Synthetic Biology: Perspectives on Risk Analysis, Governance, Communication, and ELSI

Trump, B. D., Cummings, C. L., Galaitsi, S., Kuzma, J., & Linkov, I. (2019) · Risk, systems and decisions · doi:10.1007/978-3-030-27264-7_1 · Cited by 16

Rational design of GDP‑d‑mannose mannosyl hydrolase for microbial l‑fucose production

Fu, C., Xu, X., Xie, Y., Liu, Y., Liu, M., Chen, A., Blamey, J. M., Shi, J., Zhao, S., & Sun, J. (2023) · Microbial Cell Factories · doi:10.1186/s12934-023-02060-y · Cited by 16

A comprehensive review of Microfluidic approaches in cell-free synthetic biology

Baranwal, A. K., & Maerkl, S. J. (2024) · Frontiers in Synthetic Biology · doi:10.3389/fsybi.2024.1397533 · Cited by 16

Orthogonal RNA replication enables directed evolution and Darwinian adaptation in mammalian cells

Ma, L., & Lin, Y. (2025) · Nature Chemical Biology · doi:10.1038/s41589-024-01783-2 · Cited by 16

Drug Discovery and Development via Synthetic Biology

Cobb, R. E., Luo, Y., Freestone, T. S., & Zhao, H. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-394430-6.00010-8 · Cited by 16

Logical and symbolic analysis of robust biological dynamics

Glass, L., & Siegelmann, H. T. (2010) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2010.09.005 · Cited by 15

Autonomous mobile bionanosensor networks for target tracking: A two-dimensional model

Okaie, Y., Nakano, T., Hara, T., & Nishio, S. (2014) · Nano Communication Networks · doi:10.1016/j.nancom.2014.05.003 · Cited by 16

Modeling and analyzing complex biological networks incooperating experimental information on both network topology and stable states

Zou, Y. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq333 · Cited by 15

Efflux Pump Control Alters Synthetic Gene Circuit Function

Diao, J., Charlebois, D. A., Nevozhay, D., Bódi, Z., Pál, C., & Balázsi, G. (2016) · ACS Synthetic Biology · doi:10.1021/acssynbio.5b00154 · Cited by 16

Carbohydrate active enzyme domains from extreme thermophiles: components of a modular toolbox for lignocellulose degradation

Botha, J., Mizrachi, E., Myburg, A. A., & Cowan, D. A. (2017) · Extremophiles · doi:10.1007/s00792-017-0974-7 · Cited by 16

A Dynamic Model of Resource Allocation in Response to the Presence of a Synthetic Construct

Nyström, A., Papachristodoulou, A., & Angel, A. (2018) · ACS Synthetic Biology · doi:10.1021/acssynbio.8b00015 · Cited by 17

Co-culturing fungus Penicillium citrinum and strain Citrobacter freundii improved nitrate removal and carbon utilization by promoting glyceride metabolism

Hu, L., Wang, Z., He, J., Lv, S., Zhou, B., Hrynsphan, D., Savitskaya, T., & Chen, J. (2022) · Bioresource Technology · doi:10.1016/j.biortech.2022.127563 · Cited by 16

Emergence of qualitative states in synthetic circuits driven by ultrasensitive growth feedback

Melendez-Alvarez, J. R., & Tian, X. (2022) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1010518 · Cited by 16

From a word to a world: the current situation in the interdisciplinary field of synthetic biology

Hu, X., & Rousseau, R. (2015) · PeerJ · doi:10.7717/peerj.728 · Cited by 16

First-hand, immersive full-body experiences with living cells through interactive museum exhibits

Lam, A. T., Ma, J., Barr, C., Lee, S. A., White, A. K., Yu, K. S., & Riedel-Kruse, I. H. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0272-2 · Cited by 16

Design, Fabrication, and Device Chemistry of a 3-Input-3-Output Synthetic Genetic Combinatorial Logic Circuit with a 3-Input AND Gate in a Single Bacterial Cell

Bonnerjee, D., Mukhopadhyay, S., & Bagh, S. (2019) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.9b00517 · Cited by 16

Guidelines for designing the antithetic feedback motif

Baetica, A.-A., Leong, Y. P., & Murray, R. M. (2020) · Physical Biology · doi:10.1088/1478-3975/ab8454 · Cited by 15

Biological 2-Input Decoder Circuit in Human Cells

Guinn, M. T., & Bleris, L. G. (2014) · ACS Synthetic Biology · doi:10.1021/sb4001596 · Cited by 16

Toggling a Genetic Switch Using Reinforcement LearningPreprint

Sootla, A., Strelkowa, N., Ernst, D., Barahona, M., & Stan, G.-B. V. (2013) · arXiv (Cornell University) · doi:10.48550/arxiv.1303.3183 · Cited by 16

Ecological firewalls for synthetic biology

Vidiella, B., & Solé, R. V. (2022) · iScience · doi:10.1016/j.isci.2022.104658 · Cited by 15

Synthetic Gene Circuits Combining CRISPR Interference and CRISPR Activation in E. coli : Importance of Equal Guide RNA Binding Affinities to Avoid Context-Dependent Effects

Barbier, I., Kusumawardhani, H., Chauhan, L., Harlapur, P., Jolly, M. K., & Schaerli, Y. (2023) · ACS Synthetic Biology · doi:10.1021/acssynbio.3c00375 · Cited by 17

The art of modeling gene regulatory circuits

Gómez-Schiavon, M., Montejano-Montelongo, I., Orozco-Ruiz, F. S., & Sotomayor-Vivas, C. (2024) · npj Systems Biology and Applications · doi:10.1038/s41540-024-00380-2 · Cited by 15

Advances in synthetic microbial ecosystems approach for studying ecological interactions and their influencing factors

Jiang, W., Wang, S., Gu, F., Yang, X., Qi, Q., & Liang, Q. (2025) · Engineering Microbiology · doi:10.1016/j.engmic.2025.100205 · Cited by 15

Bacterial computing with engineered populations

Amos, M., Axmann, I. M. I., Blüthgen, N., de la Cruz, F., Jaramillo, A., Rodríguez‐Patón, A., & Simmel, F. C. (2015) · Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences · doi:10.1098/rsta.2014.0218 · Cited by 15

Rational Engineering Principles in Synthetic Biology: A Framework for Quantitative Analysis and an Initial Assessment

Giese, B., Koenigstein, S., Wigger, H., Schmidt, J. C., & von Gleich, A. (2013) · Biological Theory · doi:10.1007/s13752-013-0130-2 · Cited by 15

Watch the clock—engineering biological systems to be on time

Aubel, D., & Fussenegger, M. (2010) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2010.09.003 · Cited by 15

Propellers and promoters: emerging engineering knowledge in aeronautics and synthetic biology

Schyfter, P. (2013) · Engineering Studies · doi:10.1080/19378629.2012.762651 · Cited by 15

Integrated process design for single‐cell analytical technologies

Love, J. C. (2010) · AIChE Journal · doi:10.1002/aic.12413 · Cited by 15

Processing DNA molecules as text

Shabi, U., Kaplan, S., Linshiz, G., Ben-Yehezkel, T., Buaron, H., Mazor, Y., & Shapiro, E. Y. (2010) · Systems and Synthetic Biology · doi:10.1007/s11693-010-9059-y · Cited by 15

Synthetic multicellularity

Maharbiz, M. M. (2012) · Trends in Cell Biology · doi:10.1016/j.tcb.2012.09.002 · Cited by 16

Cellular Computational Logic Using Toehold Switches

Choi, S., Lee, G., & Kim, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084265 · Cited by 16

Patterning and transferring hydrogel-encapsulated bacterial cells for quantitative analysis of synthetically engineered genetic circuits

Choi, W. S., Kim, M., Park, S., Lee, S. K., & Kim, T. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.09.069 · Cited by 15

An active intracellular device to prevent lethal disease outcomes in virus‐infected bacterial cells

Bagh, S., Mandal, M., Ang, J., & McMillen, D. R. (2010) · Biotechnology and Bioengineering · doi:10.1002/bit.22969 · Cited by 15

New Tools for Cost-Effective DNA Synthesis

Tang, N. C., Ma, S., & Tian, J. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-394430-6.00001-7 · Cited by 15

GUEST EDITORIAL: Synthetic biology: making biology into an engineering discipline

Schyfter, P., Frow, E., & Calvert, J. E. (2013) · Engineering Studies · doi:10.1080/19378629.2013.763647 · Cited by 15

Characterization of Cas9–Guide RNA OrthologsPreprint

Braff, J. L., Yaung, S. J., Esvelt, K. M., & Church, G. M. (2016) · Cold Spring Harbor Protocols · doi:10.1101/pdb.top086793 · Cited by 15

Biocircuitry and Living Programmable Materials: The Next Frontier in Synthetic Living Systems

Morones‐Ramírez, J. R. (2025) · ACS Materials Letters · doi:10.1021/acsmaterialslett.5c00238 · Cited by 14

Inbody mobile bionanosensor networks through non-diffusion-based molecular communication

Obuchi, T., Okaie, Y., Nakano, T., Hara, T., & Nishio, S. (2015) · International Conference on Communications · doi:10.1109/icc.2015.7248466 · Cited by 14

Emergence of Life from Multicomponent Mixtures of Chemicals: The Case for Experiments with Cycling Physicochemical Gradients

Spitzer, J. J. (2013) · Astrobiology · doi:10.1089/ast.2012.0924 · Cited by 14

Towards the rational design of synthetic cells with prescribed population dynamics

Dalchau, N., Smith, M. J., Martin, S., Brown, J. R., Emmott, S., & Phillips, A. (2012) · Journal of The Royal Society Interface · doi:10.1098/rsif.2012.0280 · Cited by 14

Computer-Aided Design for Synthetic Biology

Chandran, D., Bergmann, F., Sauro, H. M., & Densmore, D. M. (2011) · Springer eBooks · doi:10.1007/978-1-4419-6766-4_10 · Cited by 14

Challenges in the Application of Synthetic Biology Toward Synthesis of Commodity Products by Cyanobacteria via “Direct Conversion”

Du, W., Caicedo-Burbano, P., Hellingwerf, K. J., & dos Santos, F. B. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-0854-3_1 · Cited by 14

Identifiability and Reconstruction of Biochemical Reaction Networks from Population Snapshot Data

Eugenio Cinquemani, B. (2018) · Processes · doi:10.3390/pr6090136 · Cited by 14

Comparative analysis of three studies measuring fluorescence from engineered bacterial genetic constructs

Beal, J., Baldwin, G. S., Farny, N. G., Gershater, M. C., Haddock, T. L., Buckley-Taylor, R., Dwijayanti, A., Kiga, D., Lizarazo, M., Marken, J. P., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0252263 · Cited by 14

Synthetic biology landscape and community in Germany

Krink, N., Löchner, A. C., Cooper, H., Beisel, C. L., & Ventura, B. D. (2021) · Biotechnology Notes · doi:10.1016/j.biotno.2021.12.001 · Cited by 14

Modeling and performance evaluation of mobile bionanosensor networks for target tracking

Okaie, Y., Nakano, T., Hara, T., Hosoda, K., Hiraoka, Y., & Nishio, S. (2014) · International Conference on Communications · doi:10.1109/icc.2014.6883941 · Cited by 14

Frontiers of optofluidics in synthetic biology

Tan, C., Lo, S.-J., LeDuc, P. R., & Cheng, C. (2012) · Lab on a Chip · doi:10.1039/c2lc40828g · Cited by 14

Utilization of a calmodulin lysine methyltransferase co-expression system for the generation of a combinatorial library of post-translationally modified proteins

Magnani, R., Chaffin, B., Dick, E., Bricken, M. L., Houtz, R. L., & Bradley, L. H. (2012) · Protein Expression and Purification · doi:10.1016/j.pep.2012.09.012 · Cited by 14

Adapting to Adaptations: Behavioural Strategies that are Robust to Mutations and Other Organisational-Transformations

Egbert, M. D., & Pérez‐Mercader, J. (2016) · Scientific Reports · doi:10.1038/srep18963 · Cited by 14

Quantitative Characterization of Translational Riboregulators Using an in Vitro Transcription–Translation System

Senoussi, A., Wah, J. L. T., Shimizu, Y., Robert, J., Jaramillo, A., Findeiß, S., Axmann, I. M. I., & Estevez‐Torres, A. (2018) · ACS Synthetic Biology · doi:10.1021/acssynbio.7b00387 · Cited by 14

Towards a better metabolic engineering reference: the microbial chassis

Abram, K. Z., & Udaondo, Z. (2018) · Microbial Biotechnology · doi:10.1111/1751-7915.13363 · Cited by 14

Expanding biological control to bioelectronics with machine learning

Selberg, J. A., Jafari, M., Bradley, C., Gomez, M. M., & Rolandi, M. (2020) · APL Materials · doi:10.1063/5.0027226 · Cited by 14

Computational implementation of a tunable multicellular memory circuit for engineered eukaryotic consortia

Josep Sardanyés, A., Bonforti, A., Pueyo, N. C., Solé, R. V., & Macía, J. (2015) · Frontiers in Physiology · doi:10.3389/fphys.2015.00281 · Cited by 14

Host-aware RNA-based control of synthetic microbial consortiaPreprint

Boo, A., Mehta, H., Ledesma‐Amaro, R., & Stan, G.-B. V. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.05.15.540816 · Cited by 13

Crystals: animal, vegetable or mineral?

Hyde, S. (2015) · Interface Focus · doi:10.1098/rsfs.2015.0027 · Cited by 8

RNA-Based Sensor Systems for Affordable Diagnostics in the Age of Pandemics

Köksaldı, İ. Ç., Park, D.-W., Atilla, A., Kang, H., Kim, J., & Şeker, U. Ö. Ş. (2024) · ACS Synthetic Biology · doi:10.1021/acssynbio.3c00698 · Cited by 13

Gene circuit-based sensors

Guo, X., Li, M., & Zuo, X. (2024) · Fundamental Research · doi:10.1016/j.fmre.2024.06.011 · Cited by 14

A Microfluidic Biodisplay

Volpetti, F., Petrova, E., & Maerkl, S. J. (2017) · ACS Synthetic Biology · doi:10.1021/acssynbio.7b00088 · Cited by 13

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

van der Linden, A. J., Yelleswarapu, M., Pieters, P. A., Swank, Z., Huck, W. T. S., Maerkl, S. J., & de Greef, T. F. A. (2019) · Journal of Visualized Experiments · doi:10.3791/59655 · Cited by 13

Evolution in the Debian GNU/Linux software network: analogies and differences with gene regulatory networks

Villegas, P., Muñoz, M. A., & Bonachela, J. A. (2020) · Journal of The Royal Society Interface · doi:10.1098/rsif.2019.0845 · Cited by 13

Dichotomous feedback: a signal sequestration-based feedback mechanism for biocontroller design

Sootla, A., Delalez, N. J., Alexis, E., Norman, A., Steel, H., Wadhams, G. H., & Papachristodoulou, A. (2022) · Journal of The Royal Society Interface · doi:10.1098/rsif.2021.0737 · Cited by 13

Methods for and results from the study of design principles in molecular systems

Salvadó, B., Karathia, H., Usié, A., Vilaprinyó, E., Omholt, S. W., Albert Sorribas, B., & Alves, R. (2011) · Mathematical Biosciences · doi:10.1016/j.mbs.2011.02.005 · Cited by 13

Robustness Analysis, Prediction and Estimation for Uncertain Biochemical Networks

Streif, S., Kim, K. K., Rumschinski, P., Kishida, M., Shen, D. E., Findeisen, R., & Braatz, R. D. (2013) · IFAC Proceedings Volumes · doi:10.3182/20131218-3-in-2045.00190 · Cited by 13

Building Better Scientists through Cross-Disciplinary Collaboration in Synthetic Biology: A Report from the Genome Consortium for Active Teaching Workshop 2010

Wolyniak, M. J., Alvarez, C. J., Chandrasekaran, V., Grana, T. M., Holgado, A. M., Jones, C. J., Morris, R. W., Pereira, A. L., Stamm, J., Washington, T., et al. (2010) · CBE—Life Sciences Education · doi:10.1187/cbe.10-07-0097 · Cited by 13

Directed evolution of a synthetic RNA–protein module to create a new translational switch

Hara, T., Saito, H., & Inoue, T. (2013) · Chemical Communications · doi:10.1039/c3cc38688k · Cited by 13

Enzyme Sequestration as a Tuning Point in Controlling Response Dynamics of Signalling Networks

Feng, S., Ollivier, J. F., & Soyer, O. S. (2016) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1004918 · Cited by 13

Synthetic Biology: Programming Cells for Biomedical Applications

Hörner, M., Reischmann, N., & Weber, W. (2012) · Perspectives in biology and medicine · doi:10.1353/pbm.2012.0042 · Cited by 17

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Synthetic Biology – Engineering Biologically-based Devices and Systems

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