The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Common strategies for antigenic variation by bacterial, fungal and protozoan pathogens
Open accessAbstract
The complex relationships between infectious organisms and their hosts often reflect the continuing struggle of the pathogen to proliferate and spread to new hosts, and the need of the infected individual to control and potentially eradicate the infecting population. This has led, in the case of mammals and the pathogens that infect them, to an 'arms race', in which the highly adapted mammalian immune system has evolved to control the proliferation of infectious organisms and the pathogens have developed correspondingly complex genetic systems to evade this immune response. We review how bacterial, protozoan and fungal pathogens from distant evolutionary lineages have evolved surprisingly similar mechanisms of antigenic variation to avoid eradication by the host immune system and can therefore maintain persistent infections and ensure their transmission to new hosts.
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Evidence for the Involvement of VAR2CSA in Pregnancy-associated Malaria
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Cited by
Peeling, R. W., Mabey, D., Kamb, M. L., Chen, X.-S., Radolf, J. D., & Benzaken, A. S. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.73 · Cited by 664
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Stucki, D., Brites, D., Jeljeli, L., Coscolla, M., Liu, Q., Trauner, A., Fenner, L., Rutaihwa, L., Borrell, S., Luo, T., et al. (2016) · Nature Genetics · doi:10.1038/ng.3704 · Cited by 423
(2015) · Advances in Parasitology · doi:10.1016/bs.apar.2015.02.004 · Cited by 162
Frazer, C., Staples, M. I., Kim, Y., Hirakawa, M., Dowell, M. A., Johnson, N. V., Hernday, A. D., Ryan, V. H., Fawzi, N. L., Finkelstein, I. J., et al. (2020) · Nature Microbiology · doi:10.1038/s41564-020-0760-7 · Cited by 56
Metadata
- Authors
- Deitsch, K. W., Lukehart, S. A., & Stringer, J. R.
- Venue
- Nature Reviews Microbiology
- Published
- 2009-06-08
- Volume
- 7
- Issue
- 7
- Pages
- 493-503
- ISSN
- 1740-1526 (ISSN-L)
- 1740-1534
- OpenAlex
- W1964020301
- Cited by
- 375
- References
- 5
- FWCI
- 1.21
- Type
- journal article
- Language
- en
- Open access
- green
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