The keystone-pathogen hypothesis

Hajishengallis, George, Darveau, Richard P., Curtis, Michael A.·2012·Nature Reviews Microbiology

DOI 10.1038/nrmicro2873

Cited by (1,001)

Items 701–800 of 1,001

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Cristiane Gonçalves, Geisla Mary Silva Soares, Marcelo Faveri, Paula Juliana Pérez‐Chaparro, Eduardo Souza de Lobão Veras, Luciene Cristina Figueiredo, Gustavo Titonele Baccelli, Magda Feres · 2016 · Journal of Applied Oral Science
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The Subgingival Plaque Microbiome, Systemic Antibodies against Bacteria and Citrullinated Proteins following Periodontal Therapy
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Zsombor Prucsi, Agnieszka Zimny, Alicja Płonczyńska, Natalia Zubrzycka, Jan Potempa, Maja Sochalska · 2023 · International Journal of Molecular Sciences
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Lactobacillus helveticus SBT2171 upregulates the expression of β‐defensin and ameliorates periodontal disease caused by Porphyromonas gingivalis
Eiji Kobatake, Ryoki Kobayashi, Toshihide Kabuki, Tomoko Kurita‐Ochiai · 2019 · Microbiology and Immunology
Microbial Influences of Mucosal Immunity in Rheumatoid Arthritis
Timothy M. Wilson, Brandon J. Trent, Kristine A. Kuhn, Mary Kristen Demoruelle · 2020 · Current Rheumatology Reports
Porphyromonas gingivalis Conditioned Medium Induces Amyloidogenic Processing of the Amyloid-β Protein Precursor upon in vitro Infection of SH-SY5Y Cells
Shalini Kanagasingam, Christopher J. von Ruhland, Richard R. Welbury, Sasanka S. Chukkapalli, Sim K. Singhrao · 2022 · Journal of Alzheimer s Disease Reports
Parvimonas micra can translocate from the subgingival sulcus of the human oral cavity to colorectal adenocarcinoma
Kelly Conde‐Pérez, Elena Buetas, Pablo Aja‐Macaya, Elsa Martín‐De Arribas, Iago Iglesias‐Corrás, Noelia Trigo‐Tasende, Mohammed Nasser‐Ali, Lara S. Estévez, Soraya Rumbo‐Feal, Begoña Otero‐Alén et al. · 2023 · Molecular Oncology
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Oral microbiota–host interaction: the chief culprit of alveolar bone resorption
Jingyu Xu, Ling Yu, Surong Ye, Zitong Ye, Luyi Yang, Xiaoxi Xu · 2024 · Frontiers in Immunology
The Microbiome and Colorectal Neoplasia: Environmental Modifiers of Dysbiosis
Nancy D. Turner, Lauren Elizabeth Ritchie, Robert S. Bresalier, Robert S. Chapkin · 2013 · Current Gastroenterology Reports
Omics for Understanding the Gut‐Liver‐Microbiome Axis and Precision Medicine
Jag H. Khalsa, Linda C. Duffy, Gabriela Riscuta, Pamela E Starke-Reed, Van S. Hubbard · 2017 · Clinical Pharmacology in Drug Development
Gingipain of Porphyromonas gingivalis manipulates M1 macrophage polarization through C5a pathway
Yubo Hou, Haiyan Yu, Xinchan Liu, Gege Li, Jiahui Pan, Changyu Zheng, Weixian Yu · 2017 · In Vitro Cellular & Developmental Biology - Animal
The Distinct Immune-Stimulatory Capacities of Porphyromonas gingivalis Strains 381 and ATCC 33277 Are Determined by the fimB Allele and Gingipain Activity
Stephen R. Coats, Nutthapong Kantrong, Thao T. To, Sumita Jain, Caroline Attardo Genco, Jeffrey S. McLean, Richard P. Darveau · 2019 · Infection and Immunity
CXXC5 orchestrates Stat3/Erk/Akt signaling networks to modulate P. gingivalis-elicited autophagy in cementoblasts
Li Ma, Huan Liu, Xiaoxuan Wang, Chenxi Jiang, Siqi Yao, Yi Guo, Huiyi Wang, Zhengguo Cao · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Increased Interleukin-18 in the Gingival Tissues Evokes Chronic Periodontitis after Bacterial Infection
Kotaro Yoshinaka, Noriaki Shoji, Takashi Nishioka, Yumiko Sugawara, Tomoaki Hoshino, Shunji Sugawara, Takashi Sasano · 2014 · The Tohoku Journal of Experimental Medicine
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Gabriela Dabija‐Wolter, Sundus Saad Al‐Zubaydi, Marwan Mansoor Ali Mohammed, Vidar Bakken, Anne Isine Bolstad · 2018 · Clinical and Experimental Dental Research
Porphyromonas gingivalis infection may contribute to systemic and intracerebral amyloid-beta: implications for Alzheimer’s disease onset
Ingar Olsen, Sim K. Singhrao · 2020 · Expert Review of Anti-infective Therapy
Manipulation of Saliva-Derived Microcosm Biofilms To Resemble Dysbiotic Subgingival Microbiota
Yaling Jiang, Bernd Willem Brandt, Mark J. Buijs, Lei Cheng, Rob A. M. Exterkate, Wim Crielaard, Dongmei Deng · 2020 · Applied and Environmental Microbiology
Molecular analysis shows the presence of periodontal bacterial DNA in atherosclerotic plaques from patients with coronary artery disease
Amita Rao, Caroline D’Souza, K. Subramanyam, Praveen Rai, Biju Thomas, Mundayat Gopalakrishnan, Indrani Karunasagar, Ballamoole Krishna Kumar · 2021 · Indian Heart Journal
Oleoresins and naturally occurring compounds of Copaifera genus as antibacterial and antivirulence agents against periodontal pathogens
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Does Oral Endotoxin Contribute to Systemic Inflammation?
Camille Zenobia, Richard P. Darveau · 2022 · Frontiers in Oral Health
Oral Microbial Signatures of Tobacco Chewers and Oral Cancer Patients in India
Shriya Sawant, Jinesh A. Dugad, Deepak Parikh, Sathiyaraj Srinivasan, Harinder Singh · 2023 · Pathogens
Effects of water flossing on gingival inflammation and supragingival plaque microbiota: a 12-week randomized controlled trial
Xin Xu, Yishan Zhou, Chengcheng Liu, Леи Жао, Ling Zhang, Haolai Li, Yi Li, Xingqun Cheng · 2023 · Clinical Oral Investigations
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Structure of the lysine specific protease K gp from P orphyromonas gingivalis , a target for improved oral health
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In-vitro activity of taurolidine on single species and a multispecies population associated with periodontitis
Lilly Zollinger, Simone Schnyder, Sándor Nietzsche, Anton Sculean, Sigrun Eick · 2014 · Anaerobe
Neutrophil Mobilization by Surface-Glycan Altered Th17-Skewing Bacteria Mitigates Periodontal Pathogen Persistence and Associated Alveolar Bone Loss
Rajendra Prasad Settem, Kiyonobu Honma, Ashu Sharma · 2014 · PLoS ONE
The Oral Microbiome in Health and Disease
Ingar Olsen · 2015 · Springer eBooks
Inhibition of Sprouty2 polarizes macrophages toward an M2 phenotype by stimulation with interferon γ andPorphyromonas gingivalislipopolysaccharide
Ryo Atomura, Terukazu Sanui, Takao Fukuda, Urara Tanaka, Kyosuke Toyoda, Takaharu Taketomi, Kensuke Yamamichi, Hajime Akiyama, Fusanori Nishimura · 2016 · Immunity Inflammation and Disease
A Modified Glycosaminoglycan, GM-0111, Inhibits Molecular Signaling Involved in Periodontitis
Justin R. Savage, Abigail Pulsipher, Narayanam V. Rao, Thomas P. Kennedy, Glenn D. Prestwich, MARIA EMANUEL RYAN, Won Yong Lee · 2016 · PLoS ONE
Secretory leukocyte protease inhibitor regulates human periodontal ligament cell production of pro-inflammatory cytokines
Daniel Svensson, Alexandra Aidoukovitch, Emma Anders, Daniel Jönsson, Daniel Nebel, Bengt‐Olof Nilsson · 2017 · Inflammation Research
Porphyromonas gulae Activates Unprimed and Gamma Interferon-Primed Macrophages via the Pattern Recognition Receptors Toll-Like Receptor 2 (TLR2), TLR4, and NOD2
James A. Holden, Neil Martin O’brien-simpson, Jason C. Lenzo, Rebecca Orth, Ashley S. Mansell, Eric Charles Reynolds · 2017 · Infection and Immunity
Comparison of Oral Microbe Quantities from Tongue Samples and Subgingival Pockets
André Göhler, Stefanie Samietz, Carsten Oliver Schmidt, Thomas Kocher, Ivo Steinmetz, Birte Holtfreter · 2018 · International Journal of Dentistry
Periodontal Pathogens and Neuropsychiatric Health
Abhishek Wadhawan, Mark Allan Reynolds, Hina Makkar, Alison J. Scott, Eileen Potocki, Andrew J. Hoisington, Lisa A. Brenner, Aline Dagdag, Christopher A. Lowry, Yogesh Dwivedi et al. · 2020 · Current Topics in Medicinal Chemistry
Citrullination in periodontium is associated with Porphyromonas gingivalis
Alejandra Maldonado, Luca Pirracchio, Jean‐Claude Imber, Walter Bürgin, Burkhard Möller, Anton Sculean, Sigrun Eick · 2020 · Archives of Oral Biology
Localized microbially induced inflammation influences distant healthy tissues in the human oral cavity
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Metatranscriptome and Resistome of the Endodontic Microbiome
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Abish S. Stephen, Emma Millhouse, Leighann Sherry, Joseph Aduse‐Opoku, Shauna Culshaw, Gordon Ramage, David J. Bradshaw, Gary R. Burnett, Robert Patrick Allaker · 2016 · PLoS ONE
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Jinlian Tan, Pravin C. Patil, Frederick A. Luzzio, Donald R. Demuth · 2018 · Antimicrobial Agents and Chemotherapy
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Shokhan H. Azeez, Shanaz Mohammad Gaphor · 2019 · BioMed Research International
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C.W.I. Douglas, Kathryn L. Naylor, Chatchawal Phansopa, Andrew Michael Frey, Thomas Farmilo, Graham P. Stafford · 2014 · Advances in microbial physiology/Advances in Microbial Physiology
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Seda Arat, Aaron Spivak, Stephanie Van Horn, Elizabeth Thomas, Christopher Traini, Ganesh M. Sathe, George P. Livi, Karen A. Ingraham, Lori S. Jones, Kelly Marshall Aubart et al. · 2014 · Antimicrobial Agents and Chemotherapy
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Nan Jiang, Tianfan Cheng, Minji Wang, Gcf Chan, Lijian Jin, Hongyan Li, Hongzhe Sun · 2017 · Metallomics
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Marcin Okrój, Jan Potempa · 2019 · Frontiers in Immunology
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Carine Gomez, Pascal Chanez · 2016 · European Respiratory Journal
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Benjamin R. Belvin, Qin Gui, Justin A. Hutcherson, Janina P. Lewis · 2019 · Infection and Immunity
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Models of periodontal disease pathogenesis
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Iulia Cristina Micu, Alexandrina Muntean, Alexandra Roman, Ştefan‐Ioan Stratul, Emőke Páll, Andreea Ciurea, Andrada Șoancă, Marius Negucioiu, Lucian Barbu–Tudoran, Ada Gabriela Delean · 2023 · Antibiotics
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The role of programmed death receptor (PD‐)1/PD‐ligand (L)1 in periodontitis and cancer
Sabine Elisabeth. Groeger, Joerg Meyle · 2024 · Periodontology 2000
Role of OmpA2 surface regions ofPorphyromonas gingivalisin host-pathogen interactions with oral epithelial cells
Kathryn L. Naylor, Magdalena Widziołek, Stuart Hunt, Mary Conolly, Matthew G. Hicks, Prachi Stafford, Jan Potempa, Craig Murdoch, C.W.I. Douglas, Graham P. Stafford · 2016 · MicrobiologyOpen
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Asghar Z. Naqvi, Lin Mu, Hatice Hastürk, Thomas E. Van Dyke, Kenneth Jay Mukamal, J. Max Goodson · 2017 · Journal of Periodontology
Oral microbial community assembly under the influence of periodontitis
Hongju Chen, Shuting Peng, Lin Dai, Quan Zou, Bin Yi, Xianghong Yang, Zhanshan Sam Ma · 2017 · PLoS ONE
Effect of extracytoplasmic function sigma factors on autoaggregation, hemagglutination, and cell surface properties of Porphyromonas gingivalis
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Microbial Physiology of the Digestive Tract and Its Role in Inflammatory Bowel Diseases
Jeannette S. Messer, Eugene B. Chang · 2018 · Elsevier eBooks
Consequences of colonialism: A microbial perspective to contemporary Indigenous health
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O-Polysaccharide Plays a Major Role on the Virulence and Immunostimulatory Potential of Aggregatibacter actinomycetemcomitans During Periodontal Infection
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