The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Urinary tract infections: epidemiology, mechanisms of infection and treatment options
Open accessAbstract
Urinary tract infections (UTIs) are a severe public health problem and are caused by a range of pathogens, but most commonly by Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis and Staphylococcus saprophyticus. High recurrence rates and increasing antimicrobial resistance among uropathogens threaten to greatly increase the economic burden of these infections. In this Review, we discuss how basic science studies are elucidating the molecular details of the crosstalk that occurs at the host–pathogen interface, as well as the consequences of these interactions for the pathophysiology of UTIs. We also describe current efforts to translate this knowledge into new clinical treatments for UTIs.
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Cites
The rise of the Enterococcus: beyond vancomycin resistance
Arias, C. A., & Murray, B. E. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2761 · Cited by 1,776
Detection of Intracellular Bacterial Communities in Human Urinary Tract Infection
Rosen, D. A., Hooton, T. M., Stamm, W. E., Humphrey, P. A., & Hultgren, S. J. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040329 · Cited by 651
Self-citationShared and distinct mechanisms of iron acquisition by bacterial and fungal pathogens of humans
Caza, M., & Kronstad, J. W. (2013) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2013.00080 · Cited by 306
Garcia, E. C., Brumbaugh, A. R., & Mobley, H. L. T. (2011) · Infection and Immunity · doi:10.1128/iai.01222-10 · Cited by 256
Mucosal Immunization with Iron Receptor Antigens Protects against Urinary Tract Infection
Alteri, C. J., Hagan, E. C., Sivick, K. E., Smith, S. N., & Mobley, H. L. T. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000586 · Cited by 201
Valdebenito, M., Crumbliss, A. L., Winkelmann, G., & Hantke, K. (2006) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2006.06.003 · Cited by 145
Cited by
Sharma, S., Mohler, J., Mahajan, S. D., Schwartz, S. A., Bruggemann, L., & Aalinkeel, R. (2023) · Microorganisms · doi:10.3390/microorganisms11061614 · Cited by 993
Fiore, E., Van Tyne, D., & Gilmore, M. S. (2019) · Microbiology Spectrum · doi:10.1128/microbiolspec.gpp3-0053-2018 · Cited by 503
Multi-drug-resistant Gram-negative bacteria causing urinary tract infections: a review
Mazzariol, A., Bazaj, A., & Cornaglia, G. (2017) · Journal of Chemotherapy · doi:10.1080/1120009x.2017.1380395 · Cited by 325
The role of lipopolysaccharide-induced cell signalling in chronic inflammation
Page, M. J., Kell, D. B., & Pretorius, E. (2022) · Chronic Stress · doi:10.1177/24705470221076390 · Cited by 315
Colibactin: More Than a New Bacterial Toxin
Faïs, T., Delmas, J., Barnich, N., Bonnet, R., & Dalmasso, G. (2018) · Toxins · doi:10.3390/toxins10040151 · Cited by 227
Metadata
- Authors
- Flores-Mireles, A. L., Walker, J. N., Caparon, M., & Hultgren, S. J.
- Venue
- Nature Reviews Microbiology
- Published
- 2015-04-08
- Volume
- 13
- Issue
- 5
- Pages
- 269-284
- ISSN
- 1740-1526 (ISSN-L)
- 1740-1534
- OpenAlex
- W2031240692
- Cited by
- 4,213
- References
- 6
- FWCI
- 27.04
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Flores-Mireles, A. L., Walker, J. N., Caparon, M., & Hultgren, S. J. (2015). Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nature Reviews Microbiology. https://doi.org/10.1038/nrmicro3432
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
