HIV-1 capsid: the multifaceted key player in HIV-1 infection

Campbell, Edward M., Hope, Thomas J.·2015·Nature Reviews Microbiology

DOI 10.1038/nrmicro3503

Cited by (427)

Items 301–400 of 427

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Dina Viktorovna Glazkova, Ф. А. Урусов, Elena Vladimirovna Bogoslovskaya, German Alexandrovich Shipulin · 2020 · Molecular Biology
Genetic factors influencing HIV infection: a review
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New Antiretrovirals for HIV and Antivirals for HBV
Scott E. Lazerwith, Dustin S. Siegel, R.M. McFadden, Michael Mish, Winston C. Tse · 2017 · Elsevier eBooks
Viruses and Viral Infections in Developing Countries
Snežana Jovanović-Ćupić, Muhammad Abubakar, Ayşe Önal, Muhammad Kashif Saleemi, Ana Božović, Milena Krajnović · 2019 · IntechOpen eBooks
Piperazine-based HIV-1 entry inhibitors: Massive in silico library design and screening for gp120 attachment inhibitors
Durbis J. Castillo‐Pazos, Antonio Romo‐Mancillas, Joaquín Barroso‐Flores · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
Bibliometric analysis and visualization of research trends on HIV-1 capsid inhibitors (2000–2022)
Lin Sun, Tongchao Zhang, Shujing Xu, Xujie Zhang, Peng Zhan, Xinyong Liu · 2023 · Frontiers in Pharmacology
Structural basis of lenacapavir-induced HIV-1 capsid defects during virion maturation
Hiroki Tanaka, Reina Morita, Tomomasa Oka, Minoru Fukushima, Shunsuke Kita, Mina Sasaki, Katsumi Maenaka, Shinichi Machida · 2026 · Nature Communications
Maternal embryonic leucine zipper kinase (MELK) optimally regulates the HIV-1 uncoating process
Takara Nishiyama, Toru Takada, Hiroaki Takeuchi, Shingo Iwami · 2022 · Journal of Theoretical Biology
A systematic bioinformatics approach for large-scale identification and characterization of host-pathogen shared sequences
Stephen A. James, Hui San Ong, Ranjeev Hari, Asif M. Khan · 2021 · BMC Genomics
Investigational drugs for HIV: trends, opportunities and key players
Ronald J. Overmars, Zoë Krullaars, Thibault Mésplède · 2023 · Expert Opinion on Investigational Drugs
From exploring cancer and virus targets to discovering active peptides through mRNA display
José Brango‐Vanegas, Michel Lopes Leite, Kamila Botelho Sampaio de Oliveira, Nicolau Brito da Cunha, Octávio Luiz Franco · 2023 · Pharmacology & Therapeutics
Three prime repair exonuclease 1 preferentially degrades the integration-incompetent HIV-1 DNA through favorable kinetics, thermodynamic, structural, and conformational properties
Prem Prakash, Purva Khodke, Muthukumar Balasubramaniam, Benem-Orom Davids, Thomas Hollis, Jamaine S. Davis, Jui Pandhare, Bajarang Vasant Kumbhar, Chandravanu Dash · 2024 · Journal of Biological Chemistry
Blockade of de novo dNTP biosynthesis pathway delays HIV-1 early life cycle kinetics and dynamics
Mohammad Anwar Siddique, Michael D. McRaven, Muhammad Shoaib Arif, Edward J. Allen, Charia McKee, Shravya Honne, Tahmina Sultana, Baek Kim, Ann M. Carias, João I. Mamede et al. · 2025 · mBio
Retroviral restriction: nature's own solution
Christopher E. Jones, Áine McKnight · 2016 · Current Opinion in Infectious Diseases
Nuclear Pore Complexes, Genome Organization and HIV-1 Infection
Francesca Di Nunzio · 2018 · Springer eBooks
Фактор рестрикции ретровирусов TRIM5α: механизм действия и перспективы использования в генной терапии ВИЧ-инфекции
Д. В. Глазкова, Ф. А. Урусов, Е. В. Богословская, German Alexandrovich Shipulin · 2020 · Molecular Biology
THE BIOLOGICAL SIGNIFICANCE OF SELENIUM AND ITS PLACE IN RNA VIRAL DISEASES
T.M. Guseynov, Rugiya Tairaga Guliyeva, F.R. Yakhyayeva · 2020 · Trace Elements in Medicine (Moscow)
Single-molecule 3D imaging of HIV cellular entry by liquid-phase electron tomography
Lingli Kong, Jianfang Liu, Meng Zhang, Zhuoyang Lu, Amy Ren, Jiankang Liu, Jinping Li, Gang Ren · 2022 · Research Square
Structure of a benzosulfonamide based inhibitor – 11l - bound to a disulfide stabilised HIV-1 capsid hexamer
Michael Barnett, Lin Sun, Shujing Xu, Xinyong Liu, Peng Zhan, David C. Goldstone · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
TSAR, “Thermal Shift Analysis in R”, identifies endogenous molecules that interact with HIV-1 capsid hexamers
William M. McFadden, Xinlin Gao, Zhijiang Ye, Xin Wen, Zachary C. Lorson, Huanchun Zheng, Jessica Fahim, Andres E. Castaner, Karen A. Kirby, Stefan G. Sarafianos · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
Rare-Event Sampling using a Reinforcement Learning-Based Weighted Ensemble Method
Darian T. Yang, Alex M. Goldberg, Lillian T. Chong · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
Pharmacokinetics and tolerability of the maturation inhibitor GSK3640254 coadministered with darunavir/ritonavir and/or etravirine in healthy adults
Ying Zhang, Samit R. Joshi, Parto Yazdani, Joyce Zhan, Bo Wen, Veronica Bainbridge, Alex Ballesteros‐Perez, Martin Gartland, Max Lataillade · 2023 · British Journal of Clinical Pharmacology
HIV Biology: Detailed Insight into Virion Structural Organization and Its Pathogenesis
Deeksha Agrawal, Kailash Chand, L. Preethi, Prudhvi Lal Bhukya, Muneesh Kumar Barman · 2024 · Springer eBooks
HIV-1 capsid interactions with Nuclear Pore Complex components support nuclear entry via affinity gradient
Ivo Melčák, Ryan L. Slack, Zachary C. Lorson, Andres Emanuelli Castaner, Krisztina Ambrus, Jonathan S. Winkjer, Karen A. Kirby, Robert A. Dick, Stefan G. Sarafianos · 2026 · Proceedings of the National Academy of Sciences
Anti-capsid nanobodies function as HIV-1 capsid inhibitors by intracellular capsid degradation
Florence M. Stel, Charlotte E. J. Verkuijlen, Esther Willems, Gillian Dekkers, Raimond Heukers, Neeltje A. Kootstra, Teunis B. H. Geijtenbeek · 2026 · Communications Biology
Lenacapavir binding to immature Gag induces giant virions and causes protease-dependent inhibition of viral release
Wright Andrews Ofotsu Amesimeku, Yoshihiro Nakata, Nami Monde, Hiromi Terasawa, Hirotaka Ode, Hiroyuki Sasaki, Consolata Elias Rukondo, Takeshi Matsui, Perpetual Nyame, Md. Jakir Hossain et al. · 2026 · Proceedings of the National Academy of Sciences
HIV-1 Capsid as a Target for Antiviral Therapy
Zhiqing Zhang, Feng Zhang · 2016 · Journal of AIDS & Clinical Research
A Comprehensive Review of the Safety and Efficacy of Lenacapavir in the Treatment of Human Immunodeficiency Virus
Rajesh Hadia, Sanyam Patidar, Sunil Kardani, Sunil Bhaurao Baile, Hemraj Singh Rajput, Rahul Trivedi, Rajesh A Maheshwari · 2024 · Journal of Young Pharmacists
Lenacapavir: a first-in-class HIV-1 capsid inhibitor for the treatment of multidrug-resistant HIV infections
Dang Ding, Dazhou Shi, Shujing Xu, Yang Zhou, Xiangyi Jiang, Xinyong Liu, Alexej Dick, Peng Zhan · 2024 · Elsevier eBooks
Nucleoporins in Retroviral Replication
Anne Monette, Andrew J. Mouland · 2018 · Elsevier eBooks
HIV and Retroviruses
Mark M. Painter, Kathleen L. Collins · 2019 · Elsevier eBooks
Coordination de la décapsidation et de l’import nucléaire de VIH-1 par la transportine-1
Juliette Fernandez, Nathalie Jane Arhel · 2020 · médecine/sciences
New Diagnostic Approaches to Viral Sexually Transmitted Infections
Manola Comar, Francesco De Seta, Nunzia Zanotta, Serena Del Bue, Pasquale Ferrante · 2020 · Springer eBooks
Viral core stability assay
Tyler Milston Renner, Kasandra Bélanger, Marc-André Langlois · 2018 · BIO-PROTOCOL
La capside du virus de l’immunodéficience humaine au centre d’un engouement sans précédent
Nathalie Jane Arhel · 2021 · médecine/sciences
Overlap Intensity: An ImageJ Macro for Analyzing the HIV-1 In Situ Uncoating Assay
Zachary Ingram, Hannah Matheney, Emma Wise, Courtney Weatherford, Amy E. Hulme · 2021 · Viruses
In vitro assembly of the Rous Sarcoma Virus capsid protein into hexamer tubes under physiological conditions
Soumeya Ali Jaballah, Graham D. Bailey, Ambroise Desfosses, Jaekyung Hyun, ALOK KUMAR MITRA, Richard L. Kingston · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
Vesiculovirus G protein-based stable cell lines for continuous lentiviral vector production
Maha Tijani · 2018 · UCL Discovery (University College London)
HIV-1: Tackling the Obstacles, Which Limit the Effectiveness of the CRISPR-Cas9 Gene Editing of the T Cell Co-Receptor, CCR5
Tatiana Hillman · 2019 · Preprints.org
In situ chromatin dynamics and HIV-1 nuclear trafficking
Zhen Hou, Yao Shen, Long Chen, Juan Shen, David Ian Stuart, Peijun Zhang · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
Structural, biophysical, and virological mechanistic characterization of HIV-1 capsid-targeting antivirals
Karen A. Kirby, William M. McFadden, Lin Wang, Haijuan Du, Huanchun Zhang, Andres Emanuelli Castaner, Zachary C. Lorson, Arvin Nafisi, Anastasia Selyutina, Charlotte Luchsinger et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
HIV-1-induced cell-cell fusion: Host regulation and consequences for viral spread
Menelaos Symeonides · 2016 · ScholarWorks -A service of University of Vermont Libraries (University of Vermont)
Qualitative Characteristics of HIV-1-Specific CD4+ T Cells Responses Associated With Broadly Neutralizing Antibody Response
Ika Nindya Kadariswantiningsih · 2016 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
Expression, Purification and Characterization of Hiv-1 Capsid Precursor Protein p41
Zhiqing Zhang, Lei Wang, Shimeng Bai, Jiaming Qiao, Honglin Shen, Fang Huang, Shuangquan Gao, Shaoyong Li, Shaowei Li, Ying Gu et al. · 2018 · The Protein Journal
Studies on HIV-1 Polymerase and Its Inhibitors
Satya P. Gupta, K. Balasubramanian · 2018 · Elsevier eBooks
Investigation of HIV cure strategies in vivo in BLT humanized mice
Perry Tsai · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
HIV-1: Tackling the Obstacles that Limit the Effectiveness of CRISPR-Cas9 Gene Editing of the T Cell Co-receptor CCR5
Tatiana Hillman · 2020 · Preprints.org
Labeling HIV-1 nucleic acids during infection and effect of MOV10 in HBV replication
Maritza Nieves Puray Chavez · 2018
Multiple Functions and Disordered Nature of Nucleocapsid Proteins of Retroviruses and Hepadnaviruses
Jean Luc Darlix, Hugues de ROCQUIGNY · 2020 · IntechOpen eBooks
In silico model of infection of a CD4(+) T-cell by a human immunodeficiency type 1 virus, and a mini-review on its molecular pathophysiology
Alfonso Vivanco-Lira, José-Raúl Nieto-Saucedo · 2021 · arXiv (Cornell University)
HIV-Associated Neurocognitive Disorder (HAND) Biomarker Identification: Significance Analysis of Microarrays and Two Persuasive Approaches with Random Forest
Hansapani Rodrigo, Bryan Martinez, Roberto De La Garza, Upal Basu Roy · 2020
Novel insights into plant vascular development: disclosing a mechanism to maintain thermospermine homeostasis in the xylem
Ana Milhinhos · 2013 · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
Nanomedicines encountering HIV dementia: A guiding star for neurotherapeutics
Siddhesh S. Jadhav, Nikhil Y. Yenorkar, Ruchika M. Bondre, Megha N. Karemore, Nikhil R. Bali · 2022 · Journal of Drug Delivery Science and Technology
Faculty Opinions recommendation of HIV-1 uncoats in the nucleus near sites of integration.
Brian Eley · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Faculty Opinions recommendation of Physical properties of the HIV-1 capsid from all-atom molecular dynamics simulations.
Chandra Shekhar Verma, Yaw Sing Tan · 2017 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
RNA structural studies : implications in HIV-1 replication and the origins of life
Thomas Gremminger · 2021
A Self-Packaging gRNA 1: Gag-Pol 15 Complex Creates Genetic Feedback and Enforces HIV Infectivity
Haley Durden, Ipsita Saha, Benjamin Preece, Brian MacArthur, Abby Petersen, Wiley Peppel, Rodrigo Gallegos, Saveez Saffarian · 2022 · SSRN Electronic Journal
Evaluación de la Clonalidad B en pacientes VIH positivos en distintos estadios clínicos de la enfermedad y su asociación con la infección por el virus del Epstein Barr
Carolina Celades · 2020
HIV-1 5'UTR RNA structures: connections to infectious lifecycle and potential therapeutic applications
Seth Staller · 2021
Informatically-informed biochemical characterization of aptamer-protein complexes
Paige R. Gruenke · 2022
Competitive HIV budding suggests that a self-packaging gRNA:Gag-Pol complex directs HIV assembly and enforces infectivity
Haley Durden, Ipsita Saha, Benjamin Preece, Brian MacArthur, Abby Petersen, Wiley Peppel, Rodrigo Gallegos, Saveez Saffarian · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
Envolvimento de miosinas na infecção por HIV-1 de células mieloides
Leticia Kogachi · 2022 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
Editorial: HIV/SIV basic research update
Akio Adachi, Takaaki Koma, Masako Nomaguchi · 2023 · Frontiers in Virology
Structural and biochemical studies of virus : host interactions in HIV-1
Amanda Paz Herrera · 2023
Label-free imaging of nuclear membrane for analysis of nuclear import of viral complexes
Andrew Ten Eyck, Yen-Cheng Chen, Levi B. Gifford, Dariana Torres-Rivera, Eva L. Dyer, Gregory B. Melikyan · 2023 · Journal of Virological Methods
Investigation of the interaction between antiretroviral drugs and the mucosal microbiome in African women.
Nomacusi Sibonganjalo Lindiwe Sibeko · 2022
Competitive assembly resolves the stoichiometry of essential proteins in infectious HIV-1 virions
Haley Durden, Benjamin Preece, Rodrigo Gallegos, Ipsita Saha, Brian MacArthur, Abby Petersen, Wiley Peppel, Saveez Saffarian · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
Ações de Nef de HIV-1 na maquinaria de tráfego intracelular para neutralizar o fator de restrição SERINC5
Érika Silva Czernisz · 2018 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
Estudo sobre o tráfego intracelular de Env do HIV-1 e a manutenção da infecciosidade viral
Estela A. Pereira · 2019 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
Law and Order of Colloidal Tectonics: From Molecules to Self-Assembled Colloids
Loı̈c Leclercq · 2024 · Molecules
From Hope to Cure: A Future Perspective on HIV Research
Jyotirmoy Banerjee, Nalin Pathak, Nomaan Mehdi · 2025 · International Journal of All Research Education & Scientific Methods
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Stephen A. James, Hui San Ong, Ranjeev Hari, Khan, Asif M. · 2021 · Figshare
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Tisa Biswas, Richard E. Sutton · 2025 · Biomolecules
Stoichiometric Binding of Cyclophilin‐A to The HIV‐1 Capsid Modulates Its Mechanoelastic Properties
Juan S. Rey, Alexander J. Bryer, Juan R. Perilla · 2026 · Small
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Romina Cabrera-Rodríguez, Anna Pons-Grífols, María Pernas, Concha Casado, Rodrigo Trujillo‐González, Iria Lorenzo-Sánchez, Iriome Reyes-Castañeda, Benjamin Trinité, Julià Blanco, Agustı́n Valenzuela-Fernández · 2026 · Cell Communication and Signaling
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Mélanie Bouvin-Pley · 2015 · theses.fr (ABES)
Contrôle traductionnel des facteurs de restriction APOBEC3G/F par la protéine Vif du VIH-1
Camille Libre · 2016 · theses.fr (ABES)
Caractérisation des fonctions cellulaires du facteur de restriction viral APOBEC3A
Mathilde Niocel · 2017 · theses.fr (ABES)
Imaging of intracellular trafficking of the HIV-1 nucleocapsid protein
Iryna Lysova · 2017 · theses.fr (ABES)
Structural rearrangements of the HIV-1 genomic RNA during maturation of the viral particle
Élodie Mailler · 2017 · theses.fr (ABES)
Functional implications of the nucleoporin Nup358/RanBP2 and transport receptors in adenoviral genome delivery
Irene Carlón-Andrés · 2017 · theses.fr (ABES)
Contribution à la recherche d'une stratégie d'immunisation visant à induire une réponse anti-VIH-1 largement neutralisante
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Caractérisation et conservation des mécanismes antiviraux des protéines IFITMs
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Implication des cellules Natural Killer dans la physiopathologie des infections chroniques VIH et VHC : application à des stratégies thérapeutiques
Olivier Lucar · 2017 · theses.fr (ABES)
Characterization and targeting the dynamic recognition of Trp37-G during the interaction of NCp7 protein of HIV-1 with nucleic acids
Rajhans Sharma · 2018 · theses.fr (ABES)
Identification of viral and host mechanisms that determine innate immune activation by the DNA sensor cGAS
Matteo Gentili · 2017 · theses.fr (ABES)
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Thomas Barbin · 2017 · theses.fr (ABES)
Nucleolar distribution of the HIV-1 nucleocapsid protein investigated by the super-resolution microscopy
Oleksandr Glushonkov · 2018 · theses.fr (ABES)
Infection des macrophages par le VIH-1 : facteurs moléculaires impliqués dans la production virale et dans le développement de bactéries opportunistes
Gabrielle Lê-Bury · 2018 · theses.fr (ABES)
Mécanistique de l'incorporation de la protéine Tat du VIH-1 dans les particules virales
Malvina Schatz · 2018 · theses.fr (ABES)
Étude de la dynamique des lymphocytes TFH et B au niveau de la rate et des ganglions mésentériques et impact d'un traitement anti-apoptotique sur la dynamique de ces populations et de la réponse humorale chez le macaque rhésus infecté par le VIS
Yasmina Fortier · 2019 · theses.fr (ABES)
Etude des propriétés fonctionnelles de la glycoprotéine d'enveloppe des variants transmis du VIH-1 et de leur évolution à l'échelle individuelle et populationnelle
Maxime Beretta · 2018 · theses.fr (ABES)
Translational inhibition of the restriction factor APOBEC3G (A3G) by the HIV-1 Vif protein : role of a uORF in the 5'-UTR of A3G mRNA and identification of cellular factors
Tanja Seissler · 2019 · theses.fr (ABES)
Définition in silico d'épitopes induisant une réponse T cytotoxique en fonction de la variabilité virale du VIH-1 et de l'immunogénétique des patients
Camille Tumiotto · 2018 · theses.fr (ABES)
Diversité du Virus de l'Immunodéficience Humaine 1 (VIH-1) et évolution de la sensibilité aux anti-corps neutralisants : analyses au niveau individuel et au niveau populationnel
Karl Stéfic · 2018 · theses.fr (ABES)
Activités multiples des inhibiteurs allostériques de l’interaction entre l’Intégrase du VIH-1 et son cofacteur LEDGF/p75
Damien Bonnard · 2017 · theses.fr (ABES)
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Marwa Khammassi · 2019 · theses.fr (ABES)
Molecular architecture and fate of HIV-1 pre-integration
Guillermo Blanco-Rodriguez · 2019 · theses.fr (ABES)
Etude fonctionnelle de l'interaction entre l'intasome du VIH-1 et le nucléosome : la queue d'histone H4 comme nouveau partenaire de l'intégration
Eric Mauro · 2018 · theses.fr (ABES)
Etude de la capacité d'échappement de la glycoprotéine d'enveloppe du VIH-1 à la restriction de l'infection médiée par la protéine IFITM3
Aurélie Drouin · 2020 · theses.fr (ABES)