HIV-1 capsid: the multifaceted key player in HIV-1 infection

Campbell, Edward M., Hope, Thomas J.·2015·Nature Reviews Microbiology

DOI 10.1038/nrmicro3503

Cited by (427)

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Mohamed Mahdi, Botond Lakatos, János András Mótyán, Gyula Hoffka, József Tőzsér · 2026 · PLoS Pathogens
Targeted Degradation of Capsid by Host-Hijacking PROTAC Overcomes Drug Resistance
Mei Wang, Zeyu Peng, Yi Zhou, Yuexi Ma, Jiacheng Gui, Shujing Xu, Xiangyi Jiang, Tianyu Tang, Xinyong Liu, Christophe C. Pannecouque et al. · 2026 · Journal of Medicinal Chemistry
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Hideki Saito, Eri Miyagi, Sandra Kao, Annie Dai, Mohammad Rashid, Darian T. Yang, Rajasree Chakraborty, Chandravanu Dash, Angela M. Gronenborn, Felipe Diaz‐Griffero et al. · 2026 · Journal of Virology
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Dr. Pasham Uma, Ch. Sreya Sri, Dr. R. L. Manisha, Muvvala Sudhakar · 2026 · International Journal of Research and Review
Capsid-Targeting Biologic Achieves Broad HIV-1 Neutralization with a High Barrier to Resistance
Florence M. Stel, Esther Willems, Ad C. van Nuenen, Brigitte Boeser‐Nunnink, Teunis B. H. Geijtenbeek, Neeltje A. Kootstra · 2026 · International Journal of Molecular Sciences
Structure-guided discovery of HIV-1 capsid inhibitors: From diverse binding sites to resistance-resilient antiviral strategies
Yuyan Li, Mei Wang, Lin Sun, Shujing Xu, Peng Zhan · 2026 · European Journal of Medicinal Chemistry
Baseline Lenacapavir Resistance and Capsid Variability in Bulgaria: A Next-Generation Sequencing Study of Newly Diagnosed HIV-1 Infections
Ivailo Alexiev, Aleksandra Partsuneva, Reneta Dimitrova, Asya Kostadinova, Anna Gancheva, Lyubomira Grigorova, Kristina Stoyanova, Maria Nikolova, Radoslava Emilova, Nina Yancheva et al. · 2026 · Pathogens
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BindingDB Entry 50016172: The Discovery of GSK3640254, a Next-Generation Inhibitor of HIV-1 Maturation.
BindingDB · 2023 · UC San Diego
BindingDB Entry 50016869: Contemporary Medicinal Chemistry Strategies for the Discovery and Development of Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors.
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BindingDB Entry 50019762: Discovery, Crystallographic Studies, and Mechanistic Investigations of Novel Phenylalanine Derivatives Bearing a Quinazolin-4-one Scaffold as Potent HIV Capsid Modulators.
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BindingDB Entry 50022810: Current status of the small molecule anti-HIV drugs in the pipeline or recently approved.
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BindingDB Entry 50003139: Discovery of phenylalanine derivatives as potent HIV-1 capsid inhibitors from click chemistry-based compound library.
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BindingDB Entry 50016600: Design, synthesis, and mechanistic investigations of phenylalanine derivatives containing a benzothiazole moiety as HIV-1 capsid inhibitors with improved metabolic stability.
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BindingDB Entry 50022844: "Pseudosubstrate Envelope"/Free Energy Perturbation-Guided Design and Mechanistic Investigations of Benzothiazole HIV Capsid Modulators with High Ligand Efficiency.
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BindingDB Entry 50007691: Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities.
BindingDB · 2021 · UC San Diego
Evaluation of capsid inhibitor resistance profiles and HIV-1 subtype distribution via near-full-length genome NGS in ART-naive HIV-1 patients in Guangxi, China
Peijiang Pan, Caichang Mo, Rongfeng Chen, 廖艳研, Bingyu Liang, Xiaomei Li, Qisi Su, Yuanting Li, Feirong Chen, Yifeng Huang et al. · 2026 · Journal of Antimicrobial Chemotherapy