Regenerating CNS myelin — from mechanisms to experimental medicines
Franklin, Robin J. M., ffrench-Constant, Charles·2017·Nature Reviews Neuroscience
Cited by (647)
Items 601–647 of 647
- Preclinical gene therapy using recombinant AAV vectors in mouse models of two human diseasesYasemin Özgür Günes · 2022 · theses.fr (ABES)
- Rôle inattendu de la signalisation des androgènes dans le système nerveux central démyélinisé de la souris femelle : Identification de spécificités liées au sexe de l'animalAmina Zahaf · 2022 · theses.fr (ABES)
- Dommages de la substance blanche et impact de l'activité axonale sur l'invasion tumorale dans un modèle murin de glioblastomeQuentin Lemercier · 2024 · theses.fr (ABES)
- Contribution des neuroblastes dérivés de la zone sous ventriculaire à la régénération de la myéline dans le cerveau de souris adulte : impact des propriétés mécaniques des tissusMarie Falque · 2023 · theses.fr (ABES)
- Suivi de la naissance et de l'évolution du contenu myélinique dans les lésions de Sclérose En Plaques à l’aide d’approches d’apprentissage profond avec aprioris biomédicaux et des techniques d'imagerie avancéeThéodore Soulier · 2024 · theses.fr (ABES)
- Angiotensin II impairs the remyelination mediated by brain endothelial cell-derived exosomesYiwen Yuan, Suzhen Liang, Ao Guan, Jian Sun, Weiwei Shen, Qiang Dong, Min Guo, Mei Cui · 2026 · Acta Neuropathologica Communications
- P2X4 Drives Sex-Specific neuroprotection in autoimmune neuroinflammationPaloma Mata, Marina Bosch-Juan, Susana Luengo-Arias, Alejandro Montilla, Mariana Astiz, Arne Battefeld, Sara Carracedo, María Victoria Sánchez‐Gómez, Carlos Matute, Alberto Pérez‐Samartín et al. · 2026 · Brain Behavior and Immunity
- An improved method for high-purity isolation of oligodendrocytes from neonatal and adult mouse brainPeiyi Guo, Elisabet C. Mandon, Jie Wang, Morgan Mooney, Keith R. Reddig, Paula Vo, Madison C. Jerome, Anoushka Lotun, Jessica B. Spinelli, Guangping Gao et al. · 2026 · iScience
- Multiple sclerosis: The role of miRNAs and their implications in cellular pathwaysDoha El‐Sayed Ellakwa, Arwa Amer, Aya Ibrahim, Rana Aboeleneen, Al‐Hassan Soliman Wadan, Takwa E. Ellakwa · 2026 · Human Gene
- KDM2B ‐ PP1 Promotes Remyelination and Functional Recovery After Facial Nerve InjuryHuiyue Xu, Haoqing Yang, Yangyang Cao · 2026 · Journal of Oral Rehabilitation
- Adjunctive Non-Disease-Modifying Therapies in Multiple Sclerosis: Immunometabolic, Neuroprotective and Remyelination-Oriented ApproachesAgnieszka Damiza-Detmer, Andrzej R Glabinski · 2026 · International Journal of Molecular Sciences
- N-acetyl-L-leucine in Neurological Disorders: Mechanisms, Evidence, and Therapeutic PerspectivesMobeen Abid, Selina Akhtar, Hammad Amjad, Sabeeh Khawar Farooqui, Tasbiha Naz, Saad Shakil, Hamzah M. Alghzawi, Areesha Hafeez, Anja Vossenkaul, Chiara Brechbühl et al. · 2026 · The Cerebellum
- Microenvironmental Regulation of Central Nervous System Myelination and RemyelinationYuxuan Wang, Lingzhen Tan, Lin Lao, Xiaomeng Huang, Sheng Zhang, Sun H · 2026 · Journal of Integrative Neuroscience
- Effects of Sphingosine 1-phosphate Modulators on Central Remyelination: A Systematic Review of Animal ModelsHarley Vu, Nelson George, Junhua Xiao · 2026 · Cellular and molecular neurobiology
- GPR37 Modulates Remyelination Following Demyelinating InjuryRenana Hajbi Karasik, Anna Vainshtein, Rina Aharoni, Yael Eshed‐Eisenbach, Daniela Marazziti, Elior Peles, Hyun‐Jeong Yang · 2026 · Journal of Neuroscience
- Oligodendroglia as Active Immunomodulators in Demyelinating DiseasesJoohyun Park, So Yeong Cheon, Bhabotosh Barman, Fuzheng Guo · 2026 · Neuroscience Bulletin
- Efficacy of Tinospora cordifolia bioactives as agonists of Smoothened (Smo) receptor to promote oligodendroglial lineage induction for remyelination-based therapyShrey Dwivedi, Sneha Ranjan, Sangeeta Singh · 2026 · Journal of Molecular Graphics and Modelling
- Therapeutic Effects of Combined 6-Shogaol and Ibudilast on Neuroinflammation and Behavioral Deficits in a Cuprizone Mouse Model of Multiple SclerosisGadah Ali Alshahrany, Kholoud Ahmed Alyami, Noor Ahmed Alzahrani, Mohammad Zubair Alam, Badrah Saeed Ali Alghamdi, Ulfat M. Omar, Abeer A. Banjabi, Huda F. Alshaibi, Rana Jamalaldin Jambi, Kholoud M. Al-Otaibi et al. · 2026 · Pharmaceuticals
- Panax quinquefolius saponins promote remyelination via orchestrating HMGCS1-NPC1-MAL-mediated lipid metabolism and rebalancing JAK-STAT signaling in a cuprizone-induced demyelination modelJiali Huang, Le Sun, Lifeng Yue, Lijia Xu, H X Liu, Pei Ma, Pei‐Gen Xiao · 2026 · Journal of Ethnopharmacology
- Microglia-astrocyte crosstalk-driven metabolic-inflammatory imbalance and cerebrovascular frailty in exacerbating stroke injury during agingJiahui Hu, Menglu Wu, Yinbin Xu, Zifeng Dai, Yuefei Wu, Xiang Gao, Lifei Lian, Jingmi Wu, Yi Huang, Shengjun Zhou · 2026 · Experimental Neurology
- Eriochrome Cyanine R revisited: a standardized myelin stain protocol for thick sections of the central & peripheral nervous system across species, pathologies and disease modelsMaximiliano Torres, Fernando de Castro, Giselle Prunell · 2026 · Brain Structure and Function
- Endogenous Activation of mGlu5 Metabotropic Glutamate Receptors Is Required for Oligodendrocyte Maturation and Myelinogenesis in MiceRoxana Paula Ginerete, Roberta Facchinetti, Alessia Ceccherelli et al. · 2026 · Cells
- The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic ResistanceYuwei Li, Haitao Zhang, Jieya Zhou · 2026 · Advanced Science
- A novel small molecule remyelination therapy for multiple sclerosisYan Yang, Brain Bai, Lars J. S. Knutsen, Richard J. Hamlyn, Qiao‐Ling Cui, Jack Perry Antel, Wendy B. Macklin, Satish Medicetty, Bruce D. Trapp · 2026 · npj Drug Discovery.
- Steroid-dependent regulation of central nervous system remyelination: From gonadal hormones to chemokine signalingAbdel Moumen Ghoumari, Michaël Schumacher · 2026 · Neurobiology of Disease
- Neural Stem Cells in Multiple Sclerosis: A Comprehensive Review of Preclinical and Clinical Evidence for CNS Repair and Translational HurdlesElham Razzaghi, Arezo Azari, Ali Golchin, Aynaz Mihanfar · 2026 · Applied Biochemistry and Biotechnology
- Glia-Targeted TherapeuticsParisa Gazerani, Nielsen S Pereira, Marcos Fabio Henriques DosSantos · 2026 · Neuroglia
- GPR30 Functions as a Shared Inhibitory Signal for Both Pericyte‐Mediated Angiogenesis and Oligodendrocyte MyelinationSi-Wen Hui, Xing Gao, Bin Yu, Qi‐Jing Lei, Zhi-Yu Liu, Shuang-Ling Wu, Yong-Jie Cheng, Tao Chen, Lan Xiao, Tao Li et al. · 2026 · Glia
- Mechanisms and therapeutic potential of microglia-regulated remyelination in chronic cerebral hypoperfusionZherui Yang, Xiaoli Qin, Yunsha Zhang, Zixi Yan, Junjie Su, Shuo Kong, Guangxu Xiao, Shixin Xu · 2026 · Experimental Neurology
- Piezo1 channel: structure, mechanogating mechanism, functions, diseases and therapeutic strategyQixiang Wu, Ying Hu, Yuhan Wang, Fuqiang Zhu, Qiongyu Xu, Ling Xu, Jinguo Xu, Tao Xu · 2026 · Molecular Biomedicine
- Therapeutic targeting of G protein-coupled receptors in central nervous system disorders: from novel mechanisms to precision pharmacologyChicheng Zhou, ChunTing Zhu, Xueying Wang, Yang Yang, Jinhuan Wei · 2026 · European Journal of Pharmacology
- Crosstalk Between Oligodendrocyte Lineage Cells and CNS ‐Resident and Peripheral Immune Cells Governs Demyelination and Remyelination in Multiple SclerosisJoohyun Park, So Yeong Cheon, Fuzheng Guo · 2026 · Glia
- Maternal sleep deprivation reshapes offspring hippocampal development through a Trem2-centered microglial program revealed by single-nucleus and spatial transcriptomicsXiaobin Wu, Liuqing Yang, Yepeng Fan, Xiaohuan Li, Xiuyu Shi, Chunfang Dai, Yayan Pang, Jiaojiao Wang, Yupeng Cun, Zhifang Dong · 2026 · Molecular Psychiatry
- The shifting landscape of brain-wide myelination across the human lifespanSahar Ahmad, Khoi Minh Huynh, Guoye Lin, Pew‐Thian Yap · 2026 · Nature Communications
- Integrated analysis of single-cell transcriptome identifies a glial-neurovascular signaling trajectory in brain repair after ischemiaHanyou Liu, Zhenwei Li, Ruxu Geng, Lingui Gu, Xinjie Bao · 2026 · Biology Direct
- Rapid Generation of Functional Oligodendrocytes From Human Induced Pluripotent Stem Cells Through Small Molecule Guided DifferentiationIsabella Bienjonetti, Vincent Roy, Marie‐Josée Beaudet, Aurélie Louit, Laurie Martineau, François Berthod, Nicolas Dupré, François Gros‐Louis · 2026 · Journal of Neuroscience Research
- Effects of sphingosine-1-phosphate receptor modulators on remyelination in multiple sclerosis: evidence from in vitro experiments, animal models and human studiesVito A. G. Ricigliano · 2026 · Frontiers in Immunology
- Oligodendrocyte‐Targeted SGK1.1 Inhibition Alleviates White Matter Injury and Cognitive Impairment in Alzheimer's Disease via Modulation of HDAC2 PhosphorylationShiji Deng, Shenghan Gao, Chao Zhou, Zhen Lan, Huiya Li, Jiang Chen, Yuhao Xu, Jiashuo Li, Pinyi Liu, Siyuan Zhang et al. · 2026 · CNS Neuroscience & Therapeutics
- The transcription factor BCL11A restores differentiation potential to aged oligodendrocyte progenitor cellsTanay Ghosh, Roey Baror, Chao Zhao, Amar Sharma, Wing Hei Au, András Lakatos, Nick Goldman, Robin J.M. Franklin · 2026 · eLife
- Regulatory T cells as drivers of CNS remyelination: neuro-immune cross-talk and comparative insights from mammalian and zebrafish modelsDebasmita Baidya, Tandra Sarkar, Biman Kanti Ray, Subhra Prakash Hui · 2026 · International Reviews of Immunology
- Non-invasive visual theta entrainment modulates myelin-related and functional outcomes in an LPC-induced demyelination modelSamaneh Dehghan, Kolsoum Dehdar, Nooshin Ahmadirad, Sarina Abouei Mehrizi, Mohammad Reza Raoufy, Mohammad Javan · 2026 · PLoS ONE
- The dimorphic brain in ischemic stroke: How sex and age shape molecular pathophysiology and therapeutic responsivenessMaría Ángeles Peinado, Ángela Naranjo, Santos Blanco, Siles Eva, María Luisa del Moral, Raquel Hernández, Esther Martínez‐Lara · 2026 · Progress in Neurobiology
- Sephin1 preserves visual circuit function and retinogeniculate integrity during autoimmune inflammatory demyelinationGabrielle M. Mey, Maia Jin Classe, Jenna N. Staples, Yanan Chen, Sebastian Werneburg · 2026 · Research Square
- Rethinking the Oligodendrocyte Progenitor Cell: One Cell, Many FunctionsAlerie Guzman de la Fuente · 2026 · European Journal of Neuroscience
- Beyond Histamine Blockade: Clemastine Fumarate as a Promoter of Myelin Regeneration, Inflammatory Regulation, and Neuroimmune Modulation in CNS DisordersRohit Kumar Singh, Chandrayee Banerjee, Sidharth Mehan · 2026 · Journal of Neuroimmune Pharmacology
- Early myelin-associated histological and cellular findings following ketogenic diet or ketone ester treatment in a cuprizone/rapamycin mouse modelNima Alaeiilkhchi, Wen Zhou, Nasrin Jangjoo Ghalat, Kathleen Kolehmainen, Tyler Thomson, Anjana Rajendran, Jie Liu, Oscar Seira, Wolfram Tetzlaff · 2026 · Multiple Sclerosis and Related Disorders
- Untersuchung oligodendroglialer Zellen mit mikroskopischen MethodenYing Sun, Friederike Pfeiffer · 2026 · BIOspektrum