Regenerating CNS myelin — from mechanisms to experimental medicines
Franklin, Robin J. M., ffrench-Constant, Charles·2017·Nature Reviews Neuroscience
Cited by (647)
Items 101–200 of 647
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- Evoked potentials as a biomarker of remyelinationMoones Heidari, Abigail B. Radcliff, Gillian J. McLellan, James N. Ver Hoeve, Kore Chan, Julie A. Kiland, Nicholas S. Keuler, Benjamin K. August, Dylan J. Sebo, Aaron S. Field et al. · 2019 · Proceedings of the National Academy of Sciences
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- Oligodendroglial ring finger protein Rnf43 is an essential injury-specific regulator of oligodendrocyte maturationJianqin Niu, Guangdan Yu, Xiaorui Wang, Wenlong Xia, Yuxin Wang, Kimberly K. Hoi, Feng Mei, Lan Xiao, Jonah R. Chan, Stephen P.J. Fancy · 2021 · Neuron
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- miR‐223 promotes regenerative myeloid cell phenotype and function in the demyelinated central nervous systemGalloway, Dylan A., Blandford, Stephanie N., Berry, Tangyne, Williams, John B., Stefanelli, Mark, Ploughman, Michelle, Moore, Craig S. · 2019 · Glia
- MiR-146a promotes oligodendrocyte progenitor cell differentiation and enhances remyelination in a model of experimental autoimmune encephalomyelitisJing Zhang, Zheng Gang Zhang, Mei Lü, Yi Zhang, Xia Shang, Michael Chopp · 2019 · Neurobiology of Disease
- Vascular endothelium deploys caveolin-1 to regulate oligodendrogenesis after chronic cerebral ischemia in miceYing Zhao, Wusheng Zhu, Ting Wan, Xiaohao Zhang, Yunzi Li, Zhenqian Huang, Pengfei Xu, Kangmo Huang, Ruidong Ye, Yi Xie et al. · 2022 · Nature Communications
- Current advancements in promoting remyelination in multiple sclerosisDavid Kremer, Rainer Akkermann, Patrick Küry, Ranjan Dutta · 2018 · Multiple Sclerosis Journal
- Promises and Limitations of Neural Stem Cell Therapies for Progressive Multiple SclerosisStefano Pluchino, Jayden A. Smith, Luca Peruzzotti‐Jametti · 2020 · Trends in Molecular Medicine
- Human Glial Progenitor Cells Effectively Remyelinate the Demyelinated Adult BrainMartha S. Windrem, Steven J. Schanz, Lisa Zou, Devin Chandler-Militello, Nicholas J. Kuypers, Maiken Nedergaard, Yuan Qiang Lu, John N. Mariani, Steven A. Goldman · 2020 · Cell Reports
- Endocannabinoid signaling in the central nervous systemCésar E. Martinez Ramirez, Gonzalo Ruiz‐Pérez, Todd M. Stollenwerk, Christina Behlke, Ashley Doherty, Cecilia J. Hillard · 2022 · Glia
- Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous systemVini Tiwari, Bharat Prajapati, Yaw Asare, Alkmini Damkou, Hao Ji, Lu Liu, Nawraa Naser, Garyfallia Gouna, Katarzyna B. Leszczyńska, Jakub Mieczkowski et al. · 2024 · Immunity
- EEF1A1 deacetylation enables transcriptional activation of remyelinationMert Duman, Adrien M. Vaquie, Gianluigi Nocera, Manfred Heller, Michael Stumpe, Devanarayanan Siva Sankar, Jörn Dengjel, Dies Meijer, Teppei Yamaguchi, Patrick Matthias et al. · 2020 · Nature Communications
- Transforming growth factor‐beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitorsBaror, Roey, Neumann, Björn, Segel, Michael, Chalut, Kevin J., Fancy, Stephen P. J., Schafer, Dorothy P., Franklin, Robin J. M. · 2019 · Glia
- Key role of the gut–microbiota–brain axis via the subdiaphragmatic vagus nerve in demyelination of the cuprizone-treated mouse brainXingming Wang, Akifumi Eguchi, Yong Hua Yang, Lijia Chang, Xiayun Wan, Jiajing Shan, Youge Qu, Li Ma, Chisato Mori, Jianjun Yang et al. · 2022 · Neurobiology of Disease
- FGF/FGFR Pathways in Multiple Sclerosis and in Its Disease ModelsRanjithkumar Rajendran, Gregor Böttiger, Christine Stadelmann, Srikanth Karnati, Martin Berghoff · 2021 · Cells
- Delayed Demyelination and Impaired Remyelination in Aged Mice in the Cuprizone ModelGingele, Stefan, Henkel, Florian, Heckers, Sandra, Moellenkamp, Thiemo M., Hümmert, Martin W., Skripuletz, Thomas, Stangel, Martin, Gudi, Viktoria · 2020 · Cells
- Inactivation of sphingosine-1-phosphate receptor 2 (S1PR2) decreases demyelination and enhances remyelination in animal models of multiple sclerosisMaryamsadat Seyedsadr, Oliver Weinmann, Ana Amorim, Benjamin Victor Ineichen, Matteo Egger, Javad Mirnajafi‐Zadeh, Burkhard Becher, Mohammad Javan, Martin E. Schwab · 2018 · Neurobiology of Disease
- Stem Cell Therapies for Progressive Multiple SclerosisJayden A. Smith, Alexandra M. Nicaise, Rosana-Bristena Ionescu, Regan Hamel, Luca Peruzzotti‐Jametti, Stefano Pluchino · 2021 · Frontiers in Cell and Developmental Biology
- The Implications of Microglial Regulation in Neuroplasticity-Dependent Stroke RecoveryChenye Qiao, Zongjian Liu, Shuyan Qie · 2023 · Biomolecules
- CXCL12 induces migration of oligodendrocyte precursor cells through the CXCR4‑activated MEK/ERK and PI3K/AKT pathwaysYongyang Tian, Hong Zhen Yin, Xi Deng, Beichuan Tang, Xianjun Ren, Tao Jiang · 2018 · Molecular Medicine Reports
- Mechanistic Target of Rapamycin Regulates the Oligodendrocyte Cytoskeleton during MyelinationAminat S. Musah, Tanya L. Brown, Marisa A. Jeffries, Quan Shang, H Hashimoto, Angelina V. Evangelou, Alison Kowalski, Mona Batish, Wendy B. Macklin, Teresa L. Wood · 2020 · Journal of Neuroscience
- Myeloid‐derived suppressor cells support remyelination in a murine model of multiple sclerosis by promoting oligodendrocyte precursor cell survival, proliferation, and differentiationCarolina Melero‐Jerez, Beatriz Fernández‐Gómez, Rafael Lebrón‐Galán, María Cristina Ortega, Irene Sánchez‐de Lara, Ana Cristina Ojalvo‐Sanz, Diego Clemente, Fernando de Castro · 2020 · Glia
- Human Endogenous Retrovirus as Therapeutic Targets in Neurologic DiseaseKaren Giménez-Orenga, Hervé Perron, Elisa Oltra · 2021 · Pharmaceuticals
- The role of neural stem cells in regulating glial scar formation and repairNicaise, Alexandra M., D’Angelo, Andrea, Ionescu, Rosana-Bristena, Krzak, Grzegorz, Willis, Cory M., Pluchino, Stefano · 2022 · Cell and Tissue Research
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- Teriflunomide promotes oligodendroglial differentiation and myelinationPeter Göttle, Anastasia Manousi, David Kremer, Laura Reiche, Hans‐Peter Hartung, Patrick Küry · 2018 · Journal of Neuroinflammation
- Purinergic receptors in multiple sclerosis pathogenesisMarı́a Domercq, A. Zabala, Carlos Matute · 2018 · Brain Research Bulletin
- Epidermal Growth Factor in the CNS: A Beguiling Journey from Integrated Cell Biology to Multiple Sclerosis. An Extensive Translational OverviewGiuseppe Scalabrino · 2020 · Cellular and Molecular Neurobiology
- Glial aging and its impact on central nervous system myelin regenerationKhalil S. Rawji, Björn Neumann, Robin J.M. Franklin · 2022 · Annals of the New York Academy of Sciences
- Buyang huanwu decoction promotes remyelination via miR-760-3p/GPR17 axis after intracerebral hemorrhageYang Wang, Zhe Yu, Menghan Cheng et al. · 2024 · Journal of Ethnopharmacology
- The Rules of Attraction in Central Nervous System MyelinationRafael Almeida · 2018 · Frontiers in Cellular Neuroscience
- Scaffold-mediated sequential drug/gene delivery to promote nerve regeneration and remyelination following traumatic nerve injuries.William Ong, C. Pinese, Sing Y. Chew · 2019 · Advanced Drug Delivery Reviews
- Neural Cell Membrane-Coated Nanoparticles for Targeted and Enhanced Uptake by Central Nervous System CellsNa Zhang, Junquan Lin, Sing Yian Chew · 2021 · ACS Applied Materials & Interfaces
- Regulatory Cells in Multiple Sclerosis: From Blood to BrainLeticia Calahorra, Celia Camacho-Toledano, Mari Paz Serrano‐Regal, María Cristina Ortega, Diego Clemente · 2022 · Biomedicines
- Pivotal role of innate myeloid cells in cerebral post-ischemic sterile inflammationJun Tsuyama, Akari Nakamura, Hiroaki Ooboshi, Akihiko Yoshimura, Takashi Shichita · 2018 · Seminars in Immunopathology
- In vivo silencing of miR‐125a‐3p promotes myelin repair in models of white matter demyelinationDavide Marangon, Enrica Boda, Roberta Parolisi, Camilla Negri, Corinna Giorgi, Francesca Montarolo, Simona Perga, Antonio Bertolotto, Annalisa Buffo, Maria P. Abbracchio et al. · 2020 · Glia
- Biomimicking Fiber Platform with Tunable Stiffness to Study Mechanotransduction Reveals Stiffness Enhances Oligodendrocyte Differentiation but Impedes Myelination through YAP‐Dependent RegulationWilliam Ong, Nicolas Marinval, Junquan Lin, Mui Hoon Nai, Yee Song Chong, Coline Pinese, Sreedharan Sajikumar, Chwee Teck Lim, Charles ffrench‐Constant, Marie E. Bechler et al. · 2020 · Small
- Multiple sclerosis iPS-derived oligodendroglia conserve their properties to functionally interact with axons and glia in vivoMozafari, Sabah, Starost, Laura, Manot-Saillet, Blandine, Garcia-Diaz, Beatriz, Xu, Yu Kang T., Roussel, Delphine, Levy, Marion J. F., Ottoboni, Linda, Kim, Kee-Pyo, Schöler, Hans R. et al. · 2020 · Science Advances
- Oligodendroglia heterogeneity in the human central nervous systemLuise A. Seeker, Anna Williams · 2021 · Acta Neuropathologica
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- Ageing impairs the regenerative capacity of regulatory T cells in mouse central nervous system remyelinationAlerie Guzman de la Fuente, Marie Dittmer, Elise Jasmijn Heesbeen, Nira de la Vega Gallardo, Jessica A. White, Andrew Young, Tiree McColgan, Amy Dashwood, Katie Mayne, Sonia Cabeza‐Fernández et al. · 2024 · Nature Communications
- Emerging Cellular and Molecular Strategies for Enhancing Central Nervous System (CNS) RemyelinationMohammad Abu-Rub, Robert H. Miller · 2018 · Brain Sciences
- A Scoping Review on Biomarkers of Endothelial Dysfunction in Small Vessel Disease: Molecular Insights from Human StudiesDaniela Jaime García, Audrey Chagnot, Joanna Marguerite Wardlaw, Axel Montagne · 2023 · International Journal of Molecular Sciences
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- Neuronal activity-dependent myelin repair after strokeWanyi Jia, Yasmine Kamen, Helena Pivoňková, Ragnhildur Thóra Káradóttir · 2019 · Neuroscience Letters
- Activation of FXR by ganoderic acid A promotes remyelination in multiple sclerosis via anti-inflammation and regeneration mechanismYue Jia, Dandan Zhang, Haoran Li, Shaolei Luo, Yuhuan Xiao, Han Li, Fuchun Zhou, Chuanyue Wang, Lei Feng, Gang Wang et al. · 2021 · Biochemical Pharmacology
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- Targeting P2X4 and P2X7 receptors in multiple sclerosisMarı́a Domercq, Carlos Matute · 2019 · Current Opinion in Pharmacology
- Progesterone and fetal-neonatal neuroprotectionMichaël Schumacher, Philippe Lière, Abdel M. Ghoumari · 2020 · Best Practice & Research Clinical Obstetrics & Gynaecology
- Neurodegeneration in Multiple Sclerosis: The Role of Nrf2-Dependent PathwaysPaloma P. Maldonado, Coram Guevara, Margrethe A. Olesen, Juan Andres Orellana, Rodrigo A. Quintanilla, Fernando C. Ortíz · 2022 · Antioxidants
- One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2Chanoumidou, Konstantina, Hernández-Rodríguez, Benjamín, Windener, Farina, Thomas, Christian, Stehling, Martin, Mozafari, Sabah, Albrecht, Stefanie, Ottoboni, Linda, Antel, Jack, Kim, Kee-Pyo et al. · 2021 · Stem Cell Reports
- The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelinationMcMurran, Christopher E., Guzman de la Fuente, Alerie, Penalva, Rosana, Ben Menachem-Zidon, Ofra, Dombrowski, Yvonne, Falconer, John, Gonzalez, Ginez A., Zhao, Chao, Krause, Fynn N., Young, Adam M. H. et al. · 2019 · Proceedings of the National Academy of Sciences
- Long-term in vivo three-photon imaging reveals region-specific differences in healthy and regenerative oligodendrogenesisMichael Andrew Thornton, Gregory L. Futia, Michael E. Stockton, Samuel A. Budoff, Alexandra N. Ramirez, Baris N. Ozbay, Omer Tzang, Karl Kilborn, Alon Poleg-Polsky, Diego Restrepo et al. · 2024 · Nature Neuroscience
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- Rescuing the negative impact of human endogenous retrovirus envelope protein on oligodendroglial differentiation and myelinationPeter Göttle, Moritz Förster, Joel Gruchot, David Kremer, Hans Peter Hartung, Hervé Perron, Patrick Küry · 2018 · Glia
- Increased Remyelination and Proregenerative Microglia Under Siponimod Therapy in Mechanistic ModelsMichael Dietrich, Christina Hecker, Elodie Martin, Dominique Langui, Michael Gliem, Bruno Stankoff, Catherine Lubetzki, Joel Gruchot, Peter Göttle, Andrea Issberner et al. · 2022 · Neurology Neuroimmunology & Neuroinflammation
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- Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelinationFrancisco J. Rivera, Alerie Guzman de la Fuente, Chao Zhao, Maria Elena Silva, Ginez A. González, Roman Wodnar, Martina Feichtner, Simona Lange, Oihana Errea, Eleni Priglinger et al. · 2019 · Glia
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- DCX+ neuronal progenitors contribute to new oligodendrocytes during remyelination in the hippocampusBarbara Klein, Heike Mrowetz, Christina Kreutzer, Peter Rotheneichner, Pia Zaunmair, Simona Lange, Roland Coras, Sébastien Couillard‐Després, Francisco J. Rivera, Ludwig Aigner · 2020 · Scientific Reports
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- TREM2 deficiency inhibits microglial activation and aggravates demyelinating injury in neuromyelitis optica spectrum disorderYun‐Fan You, Man Chen, Yue Tang, Wen-Xiang Yu, Xiao‐Wei Pang, Yun‐Hui Chu, Hang Zhang, Ke Shang, Gang Deng, Luo‐Qi Zhou et al. · 2023 · Journal of Neuroinflammation
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- Low-level laser therapy modulates demyelination in miceKatherine Chuere Nunes Duarte, Thaís Torres Soares, Angela Maria Paiva Magri, Lívia Assis Garcia, Luciana de Paula Le Sueur, Ana Cláudia Muniz Rennó, Gláucia Monteiro de Castro · 2018 · Journal of Photochemistry and Photobiology B Biology
- Myelin Pathology Beyond White Matter in Tuberous Sclerosis Complex (TSC) Cortical TubersAngelika Mühlebner, Jackelien van Scheppingen, Andrew de Neef, Anika Bongaarts, Till S. Zimmer, James Dominic Mills, Floor E. Jansen, Wim G.M. Spliet, Pavel Kršek, Josef Zámečnı́k et al. · 2020 · Journal of Neuropathology & Experimental Neurology
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- Targeting Fibronectin to Overcome Remyelination Failure in Multiple Sclerosis: The Need for Brain- and Lesion-Targeted Drug DeliveryPauline E. M. van Schaik, Inge S. Zuhorn, Wia Baron · 2022 · International Journal of Molecular Sciences
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- CRISPR-edited human ES-derived oligodendrocyte progenitor cells improve remyelination in rodentsWagstaff, Laura J., Bestard-Cuche, Nadine, Kaczmarek, Maja, Fidanza, Antonella, McNeil, Lorraine, Franklin, Robin J. M., Williams, Anna C. · 2024 · Nature Communications
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- Neural regeneration in the human central nervous system—from understanding the underlying mechanisms to developing treatments. Where do we stand today?Christopher Elnan Kvistad, Torbjørn Kråkenes, Sonia Gavasso, Lars Bø · 2024 · Frontiers in Neurology
- The fatty acid binding protein FABP7 is required for optimal oligodendrocyte differentiation during myelination but not during remyelinationSarah Foerster, Alerie Guzman de la Fuente, Yoshiteru Kagawa, Theresa Bartels, Yuji Owada, Robin J.M. Franklin · 2020 · Glia