The DOI matches its Crossref record; 118 of the 118 references it cites were found in a registry or an index.
Astrocyte Ca2+ signalling: an unexpected complexity
Open accessAbstract
Astrocyte Ca(2+) signalling has been proposed to link neuronal information in different spatial-temporal dimensions to achieve a higher level of brain integration. However, some discrepancies in the results of recent studies challenge this view and highlight key insufficiencies in our current understanding. In parallel, new experimental approaches that enable the study of astrocyte physiology at higher spatial-temporal resolution in intact brain preparations are beginning to reveal an unexpected level of compartmentalization and sophistication in astrocytic Ca(2+) dynamics. This newly revealed complexity needs to be attentively considered in order to understand how astrocytes may contribute to brain information processing.
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“astrocyte interactions with synaptic circuits are multimodal and multiscale, occur under physiological conditions 2-5 and contribute to behavior 6-8 .”
From Astrocyte function from information processing to cognition and cognitive impairment (2019) · cites this paper as [5]
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Ultrasensitive fluorescent proteins for imaging neuronal activity
Chen, T.-W., Wardill, T. J., Sun, Y., Pulver, S. R., Renninger, S. L., Baohan, A., Schreiter, E. R., Kerr, R. A., Orger, M. B., Jayaraman, V., et al. (2013) · Nature · doi:10.1038/nature12354 · Cited by 6,474
Calcium signalling: dynamics, homeostasis and remodelling
Berridge, M. J., Bootman, M. D., & Roderick, H. L. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1155 · Cited by 5,719
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
Miyawaki, A., Llopis, J. L., Heim, R., McCaffery, J. M., Adams, J. A., Ikura, M., & Tsien, R. Y. (1997) · Nature · doi:10.1038/42264 · Cited by 3,250
Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators
Tian, L., Hires, S. A., Mao, T., Huber, D., Chiappe, M. E., Chalasani, S. H., Petreanu, L., Akerboom, J., McKinney, S. A., Schreiter, E. R., et al. (2009) · Nature Methods · doi:10.1038/nmeth.1398 · Cited by 1,967
Calcium oscillations increase the efficiency and specificity of gene expression
Dolmetsch, R. E., Xu, K., & Lewis, R. S. (1998) · Nature · doi:10.1038/31960 · Cited by 1,896
Astrocytes, from brain glue to communication elements: the revolution continues
Volterra, A., & Meldolesi, J. (2005) · Nature reviews. Neuroscience · doi:10.1038/nrn1722 · Cited by 1,837
Self-citationTripartite synapses: astrocytes process and control synaptic information
Perea, G., Navarrete, M., & Araque, A. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2009.05.001 · Cited by 1,820
Glutamate-mediated astrocyte–neuron signalling
Parpura, V., Basarsky, T. A., Liu, F., Jeftinija, K., Jeftinija, S., & Haydon, P. G. (1994) · Nature · doi:10.1038/369744a0 · Cited by 1,768
Protoplasmic Astrocytes in CA1 Stratum Radiatum Occupy Separate Anatomical Domains
Bushong, E. A., Martone, M. E., Jones, Y. Z., & Ellisman, M. H. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-01-00183.2002 · Cited by 1,578
Grienberger, C., & Konnerth, A. (2012) · Neuron · doi:10.1016/j.neuron.2012.02.011 · Cited by 1,459
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- Volterra, A. in Neuroglia (eds Kettenmann, H. & Ransom, B. R.) 816–823 (Oxford Univ. Press, 2013).
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Verkhratsky, A., & Nedergaard, M. (2018) · Physiological Reviews · doi:10.1152/physrev.00042.2016 · Cited by 1,678
Astrocyte calcium signaling: the third wave
Bazargani, N., & Attwell, D. (2016) · Nature Neuroscience · doi:10.1038/nn.4201 · Cited by 998
Astrocyte function from information processing to cognition and cognitive impairment
Santello, M., Toni, N., & Volterra, A. (2019) · Nature Neuroscience · doi:10.1038/s41593-018-0325-8 · Cited by 737
Self-citationFunction and therapeutic value of astrocytes in neurological diseases
Lee, H.-G., Wheeler, M. A., & Quintana, F. J. (2022) · Nature Reviews Drug Discovery · doi:10.1038/s41573-022-00390-x · Cited by 662
Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration
Patani, R., Hardingham, G. E., & Liddelow, S. A. (2023) · Nature Reviews Neurology · doi:10.1038/s41582-023-00822-1 · Cited by 531
Metadata
- Authors
- Volterra, A., Liaudet, N., & Savtchouk, I.
- Affiliations
- University of Lausanne (CH)
- Corresponding author
- Volterra, Andrea
- Venue
- Nature Reviews Neuroscience
- Published
- 2014-04-17
- Volume
- 15
- Issue
- 5
- Pages
- 327-335
- ISSN
- 1471-003X (ISSN-L)
- 1471-0048
- OpenAlex
- W1972077052
- Cited by
- 446
- References
- 117
- Citations by year
- 2026: 15 · 2025: 32 · 2024: 27 · 2023: 32 · 2022: 27 · 2021: 43 · 2020: 44 · 2019: 52 · 2018: 50 · 2017: 37 · 2016: 38 · 2015: 43 · 2014: 6
- FWCI
- 4.66
- Type
- journal article
- Language
- en
- Open access
- green
- iris.unil.ch
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature reviews. Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- IRIS (submittedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
- SERVAL (Université de Lausanne) (submittedVersion, other-oa)
- Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (140999, 31003A)
- FP7 Ideas: European Research Council (340368)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- astrocytes, calcium signaling, calcium dynamics, synaptic function, brain information processing, astrocyte-neuron interaction, brain integration
- MeSH terms
- Animals, Astrocytes, Brain, Calcium, Humans, Synapses, Calcium Signaling
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