The DOI matches its Crossref record; 118 of the 118 references it cites were found in a registry or an index.
Astrocyte Ca2+ signalling: an unexpected complexity
Open accessAbstract
Astrocyte Ca(2+) signalling has been proposed to link neuronal information in different spatial-temporal dimensions to achieve a higher level of brain integration. However, some discrepancies in the results of recent studies challenge this view and highlight key insufficiencies in our current understanding. In parallel, new experimental approaches that enable the study of astrocyte physiology at higher spatial-temporal resolution in intact brain preparations are beginning to reveal an unexpected level of compartmentalization and sophistication in astrocytic Ca(2+) dynamics. This newly revealed complexity needs to be attentively considered in order to understand how astrocytes may contribute to brain information processing.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“astrocyte interactions with synaptic circuits are multimodal and multiscale, occur under physiological conditions 2-5 and contribute to behavior 6-8 .”
From Astrocyte function from information processing to cognition and cognitive impairment (2019) · cites this paper as [5]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Ultrasensitive fluorescent proteins for imaging neuronal activity
Chen, T.-W., Wardill, T. J., Sun, Y., Pulver, S. R., Renninger, S. L., Baohan, A., Schreiter, E. R., Kerr, R. A., Orger, M. B., Jayaraman, V., et al. (2013) · Nature · doi:10.1038/nature12354 · Cited by 6,474
Calcium signalling: dynamics, homeostasis and remodelling
Berridge, M. J., Bootman, M. D., & Roderick, H. L. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1155 · Cited by 5,719
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
Miyawaki, A., Llopis, J. L., Heim, R., McCaffery, J. M., Adams, J. A., Ikura, M., & Tsien, R. Y. (1997) · Nature · doi:10.1038/42264 · Cited by 3,250
Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators
Tian, L., Hires, S. A., Mao, T., Huber, D., Chiappe, M. E., Chalasani, S. H., Petreanu, L., Akerboom, J., McKinney, S. A., Schreiter, E. R., et al. (2009) · Nature Methods · doi:10.1038/nmeth.1398 · Cited by 1,967
Calcium oscillations increase the efficiency and specificity of gene expression
Dolmetsch, R. E., Xu, K., & Lewis, R. S. (1998) · Nature · doi:10.1038/31960 · Cited by 1,896
Astrocytes, from brain glue to communication elements: the revolution continues
Volterra, A., & Meldolesi, J. (2005) · Nature reviews. Neuroscience · doi:10.1038/nrn1722 · Cited by 1,837
Self-citationTripartite synapses: astrocytes process and control synaptic information
Perea, G., Navarrete, M., & Araque, A. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2009.05.001 · Cited by 1,820
Glutamate-mediated astrocyte–neuron signalling
Parpura, V., Basarsky, T. A., Liu, F., Jeftinija, K., Jeftinija, S., & Haydon, P. G. (1994) · Nature · doi:10.1038/369744a0 · Cited by 1,768
Protoplasmic Astrocytes in CA1 Stratum Radiatum Occupy Separate Anatomical Domains
Bushong, E. A., Martone, M. E., Jones, Y. Z., & Ellisman, M. H. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-01-00183.2002 · Cited by 1,578
Grienberger, C., & Konnerth, A. (2012) · Neuron · doi:10.1016/j.neuron.2012.02.011 · Cited by 1,459
Long-term potentiation depends on release of d-serine from astrocytes
Henneberger, C., Papouin, T., Oliet, S. H. R., & Rusakov, D. A. (2010) · Nature · doi:10.1038/nature08673 · Cited by 1,389
Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging
Akerboom, J., Chen, T., Wardill, T. J., Tian, L., Marvin, J. S., Mutlu, S., Calderón, N. C., Esposti, F., Borghuis, B. G., Sun, X. R., et al. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.2601-12.2012 · Cited by 1,289
Astrocytic Purinergic Signaling Coordinates Synaptic Networks
Pascual, O., Casper, K. B., Kubera, C., Zhang, J., Revilla-Sanchez, R., Sul, J.-Y., Takano, H., Moss, S. J., McCarthy, K., & Haydon, P. G. (2005) · Science · doi:10.1126/science.1116916 · Cited by 1,280
Sensitivity of CaM Kinase II to the Frequency of Ca 2+ Oscillations
De Koninck, P., & Schulman, H. (1998) · Science · doi:10.1126/science.279.5348.227 · Cited by 1,269
Microdomains of Intracellular Ca2+: Molecular Determinants and Functional Consequences
Rizzuto, R., & Pozzan, T. (2005) · Physiological Reviews · doi:10.1152/physrev.00004.2005 · Cited by 1,234
Prostaglandins stimulate calcium-dependent glutamate release in astrocytes
Bezzi, P., Carmignoto, G., Pasti, L., Vesce, S., Rossi, D., Rizzini, B. L., Pozzan, T., & Volterra, A. (1998) · Nature · doi:10.1038/34651 · Cited by 1,143
Self-citationA TECHNIQUE FOR ULTRACRYOTOMY OF CELL SUSPENSIONS AND TISSUES
Tokuyasu, K. T. (1973) · The Journal of Cell Biology · doi:10.1083/jcb.57.2.551 · Cited by 1,080
Fellin, T., Pascual, O., Gobbo, S., Pozzan, T., Haydon, P. G., & Carmignoto, G. (2004) · Neuron · doi:10.1016/j.neuron.2004.08.011 · Cited by 1,005
Emerging roles of astrocytes in neural circuit development
Clarke, L. E., & Barres, B. A. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3484 · Cited by 975
Glia-Derived d-Serine Controls NMDA Receptor Activity and Synaptic Memory
Panatier, A., Theodosis, D. T., Mothet, J.-P., Touquet, B., Pollegioni, L., Poulain, D. A., & Oliet, S. H. R. (2006) · Cell · doi:10.1016/j.cell.2006.02.051 · Cited by 934
Astrocytes Control Breathing Through pH-Dependent Release of ATP
Gourine, A. V., Kasymov, V., Marina, N., Tang, F., Figueiredo, M. F., Lane, S., Teschemacher, A. G., Spyer, K. M., Deisseroth, K. A., & Kasparov, S. (2010) · Science · doi:10.1126/science.1190721 · Cited by 856
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression
Li, W., Llopis, J., Whitney, M. A., Zlokarnik, G., & Tsien, R. Y. (1998) · Nature · doi:10.1038/31965 · Cited by 839
Neuronal activity triggers calcium waves in hippocampal astrocyte networks
Dani, J. W., Chernjavsky, A., & Smith, S. J. (1992) · Neuron · doi:10.1016/0896-6273(92)90271-e · Cited by 823
Pasti, L., Volterra, A., Pozzan, T., & Carmignoto, G. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-20-07817.1997 · Cited by 811
Self-citationGlutamate exocytosis from astrocytes controls synaptic strength
Jourdain, P., Bergersen, L. H., Bhaukaurally, K., Bezzi, P., Santello, M., Domercq, M., Matute, C., Tonello, F., Gundersen, V., & Volterra, A. (2007) · Nature Neuroscience · doi:10.1038/nn1849 · Cited by 806
Self-citationSulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
Nimmerjahn, A., Kirchhoff, F., Kerr, J. N. D., & Helmchen, F. (2004) · Nature Methods · doi:10.1038/nmeth706 · Cited by 784
Brain metabolism dictates the polarity of astrocyte control over arterioles
Gordon, G. R., Choi, H. B., Rungta, R. L., Ellis‐Davies, G. C. R., & MacVicar, B. A. (2008) · Nature · doi:10.1038/nature07525 · Cited by 770
Synaptic Islands Defined by the Territory of a Single Astrocyte
Halassa, M. M., Fellin, T., Takano, H., Dong, J.-H., & Haydon, P. G. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1419-07.2007 · Cited by 767
Integrated Brain Circuits: Astrocytic Networks Modulate Neuronal Activity and Behavior
Halassa, M. M., & Haydon, P. G. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135843 · Cited by 763
Calcium gradients and buffers in bovine chromaffin cells.
Neher, E., & Augustine, G. J. (1992) · The Journal of Physiology · doi:10.1113/jphysiol.1992.sp019127 · Cited by 753
Akerboom, J., Calderón, N. C., Tian, L., Wabnig, S., Prigge, M., Tolö, J., Gordus, A. G., Orger, M. B., Severi, K. E., Macklin, J. J., et al. (2013) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2013.00002 · Cited by 736
Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice
Kuchibhotla, K. V., Lattarulo, C. R., Hyman, B. T., & Bacskai, B. J. (2009) · Science · doi:10.1126/science.1169096 · Cited by 729
Astrocytes Potentiate Transmitter Release at Single Hippocampal Synapses
Perea, G., & Araque, A. (2007) · Science · doi:10.1126/science.1144640 · Cited by 727
Microdomains for neuron–glia interaction: parallel fiber signaling to Bergmann glial cells
Grosche, J., Matyash, V., Möller, T., Verkhratsky, A., Reichenbach, A., & Kettenmann, H. (1999) · Nature Neuroscience · doi:10.1038/5692 · Cited by 700
Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo
Wang, X., Lou, N., Xu, Q., Tian, G.-F., Peng, W. G., Han, X., Kang, J., Takano, T., & Nedergaard, M. (2006) · Nature Neuroscience · doi:10.1038/nn1703 · Cited by 685
Hippocampal AstrocytesIn SituRespond to Glutamate Released from Synaptic Terminals
Porter, J. T., & McCarthy, K. D. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-16-05073.1996 · Cited by 672
Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate
Bezzi, P., Gundersen, V., Galbete, J. L., Seifert, G., Steinhäuser, C., Pilati, E., & Volterra, A. (2004) · Nature Neuroscience · doi:10.1038/nn1246 · Cited by 671
Self-citationTuned Responses of Astrocytes and Their Influence on Hemodynamic Signals in the Visual Cortex
Schummers, J., Yu, H., & Sur, M. (2008) · Science · doi:10.1126/science.1156120 · Cited by 651
Astrocytes Are Endogenous Regulators of Basal Transmission at Central Synapses
Panatier, A., Vallée, J., Haber, M., Murai, K. K., Lacaille, J.-C., & Robitaille, R. (2011) · Cell · doi:10.1016/j.cell.2011.07.022 · Cited by 650
Spontaneous astrocytic Ca2+ oscillations in situ drive NMDAR-mediated neuronal excitation
Parri, H. R., Gould, T. M., & Crunelli, V. (2001) · Nature Neuroscience · doi:10.1038/90507 · Cited by 635
Hippocampal Astrocytes In Situ Respond to Glutamate Released from Synaptic Terminals
Porter, J. T., & McCarthy, K. D. (2021) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/s4kv-rg05 · Cited by 561
Ca2+ buffering and action potential-evoked Ca2+ signaling in dendrites of pyramidal neurons
Helmchen, F., Imoto, K., & Sakmann, B. (1996) · Biophysical Journal · doi:10.1016/s0006-3495(96)79653-4 · Cited by 559
Local Ca2+ detection and modulation of synaptic release by astrocytes
Di Castro, M. A., Chuquet, J., Liaudet, N., Bhaukaurally, K., Santello, M., Bouvier, D., Tiret, P., & Volterra, A. (2011) · Nature Neuroscience · doi:10.1038/nn.2929 · Cited by 529
Self-citationGlutamate-Dependent Neuroglial Calcium Signaling Differs Between Young and Adult Brain
Sun, W., McConnell, E., Paré, J., Xu, Q., Chen, M. J., Peng, W., Lovatt, D., Han, X., Smith, Y., & Nedergaard, M. (2013) · Science · doi:10.1126/science.1226740 · Cited by 523
Han, J., Kesner, P., Metna-Laurent, M., Duan, T., Xu, L., Georges, F., Koehl, M., Abrous, D. N., Mendizabal-Zubiaga, J., Grandes, P., et al. (2012) · Cell · doi:10.1016/j.cell.2012.01.037 · Cited by 514
TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3
Shigetomi, E., Tong, X., Kwan, K. Y., Corey, D. P., & Khakh, B. S. (2011) · Nature Neuroscience · doi:10.1038/nn.3000 · Cited by 491
Perea, G., & Araque, A. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3965-04.2005 · Cited by 488
Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes.
Navarrete, M., & Araque, A. (2010) · Neuron · doi:10.1016/j.neuron.2010.08.043 · Cited by 480
Mothet, J., Pollegioni, L., Ouanounou, G., Martineau, M., Fossier, P., & Baux, G. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408483102 · Cited by 461
A neuron–glia signalling network in the active brain
Bezzi, P., & Volterra, A. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00223-3 · Cited by 446
Self-citationCalcium Dynamics of Cortical Astrocytic Networks In Vivo
Hirase, H., Qian, L., Barthó, P., & Buzsáki, G. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020096 · Cited by 421
Hippocampal Short- and Long-Term Plasticity Are Not Modulated by Astrocyte Ca 2+ Signaling
Agulhon, C., Fiacco, T. A., & McCarthy, K. D. (2010) · Science · doi:10.1126/science.1184821 · Cited by 409
GABAergic network activation of glial cells underlies hippocampal heterosynaptic depression
Serrano, A., Haddjeri, N., Lacaille, J.-C., & Robitaille, R. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.5255-05.2006 · Cited by 398
Shigetomi, E., Bushong, E. A., Haustein, M. D., Tong, X., Jackson‐Weaver, O., Kracun, S., Xu, J. P., Sofroniew, M. V., Ellisman, M. H., & Khakh, B. S. (2013) · The Journal of General Physiology · doi:10.1085/jgp.201210949 · Cited by 396
Astrocytes Mediate In Vivo Cholinergic-Induced Synaptic Plasticity
Navarrete, M., Perea, G., de Sevilla, D. F., Gómez-Gonzalo, M., Núñez, A., Martín, E. D., & Araque, A. (2012) · PLoS Biology · doi:10.1371/journal.pbio.1001259 · Cited by 387
TNFα Controls Glutamatergic Gliotransmission in the Hippocampal Dentate Gyrus
Santello, M., Bezzi, P., & Volterra, A. (2011) · Neuron · doi:10.1016/j.neuron.2011.02.003 · Cited by 384
Self-citationAstrocyte Calcium Signaling Transforms Cholinergic Modulation to Cortical Plasticity In Vivo
Takata, N., Mishima, T., Hisatsune, C., Nagai, T., Ebisui, E., Mikoshiba, K., & Hirase, H. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.5289-11.2011 · Cited by 382
Characteristics of GABAB receptor binding sites on rat whole brain synaptic membranes
Bowery, N. G., Hill, D. R., & Hudson, A. L. (1983) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1983.tb09380.x · Cited by 381
Thomas, D., Tovey, S. C., Collins, T. J., Bootman, M. D., Berridge, M. J., & Lipp, P. (2000) · Cell Calcium · doi:10.1054/ceca.2000.0152 · Cited by 378
Katona, G., Szalay, G., Maák, P. A., Kaszás, A., Veress, M., Hillier, D., Chiovini, B., Vizi, E. S., Roska, B., & Rózsa, B. J. (2012) · Nature Methods · doi:10.1038/nmeth.1851 · Cited by 367
Petravicz, J., Fiacco, T. A., & McCarthy, K. D. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5572-07.2008 · Cited by 364
Vesicular Glutamate Transporter-Dependent Glutamate Release from Astrocytes
Montana, V., Ni, Y., Sunjara, V., Hua, X. J., & Parpura, V. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3770-03.2004 · Cited by 363
Astrocyte signaling controls spike timing–dependent depression at neocortical synapses
Min, R., & Nevian, T. (2012) · Nature Neuroscience · doi:10.1038/nn.3075 · Cited by 361
Fiacco, T. A., & McCarthy, K. D. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2859-03.2004 · Cited by 355
TREK-1 and Best1 Channels Mediate Fast and Slow Glutamate Release in Astrocytes upon GPCR Activation
Woo, D. H., Han, K.-S., Shim, J. W., Yoon, B., Kim, E., Bae, J. Y., Oh, S., Hwang, E. M., Marmorstein, A. D., Bae, Y. C., et al. (2012) · Cell · doi:10.1016/j.cell.2012.09.005 · Cited by 350
Nett, W., Oloff, S., & McCarthy, K. D. (2002) · Journal of Neurophysiology · doi:10.1152/jn.00268.2001 · Cited by 347
Shigetomi, E., Jackson‐Weaver, O., Huckstepp, R. T. R., O’Dell, T. J., & Khakh, B. S. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.5779-12.2013 · Cited by 322
Motor Behavior Activates Bergmann Glial Networks
Nimmerjahn, A., Mukamel, E. A., & Schnitzer, M. J. (2009) · Neuron · doi:10.1016/j.neuron.2009.03.019 · Cited by 317
Fiacco, T. A., Agulhon, C., Taves, S., Petravicz, J., Casper, K. B., Dong, X., Chen, J., & McCarthy, K. D. (2007) · Neuron · doi:10.1016/j.neuron.2007.04.032 · Cited by 316
Cytosolic Calcium Oscillations in Astrocytes May Regulate Exocytotic Release of Glutamate
Pasti, L., Zonta, M., Pozzan, T., Vicini, S., & Carmignoto, G. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-02-00477.2001 · Cited by 304
Astrocytes Modulate Neural Network Activity by Ca 2+ -Dependent Uptake of Extracellular K +
Wang, F., Smith, N., Xu, Q., Fujita, T., Baba, A., Matsuda, T., Takano, T., Bekar, L. K., & Nedergaard, M. (2012) · Science Signaling · doi:10.1126/scisignal.2002334 · Cited by 304
Characteristics of GABABreceptor binding sites on rat whole brain synaptic membranes
Bowery, N. G., Hill, D. R., & Hudson, A. L. (1997) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1997.tb06835.x · Cited by 291
Lavialle, M., Aumann, G., Anlauf, E., Pröls, F., Arpin, M., & Derouiche, A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1100957108 · Cited by 283
Verkhratsky, A., & Kirchhoff, F. (2007) · The Neuroscientist · doi:10.1177/1073858406294270 · Cited by 280
Imaging Calcium Concentration Dynamics in Small Neuronal Compartments
Yasuda, R., Nimchinsky, E. A., Scheuß, V., Pologruto, T. A., Oertner, T. G., Sabatini, B. L., & Svoboda, K. (2004) · Science s STKE · doi:10.1126/stke.2192004pl5 · Cited by 278
Shigetomi, E., Bowser, D. N., Sofroniew, M. V., & Khakh, B. S. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1717-08.2008 · Cited by 272
Ohkura, M., Sasaki, T., Sadakari, J., Gengyo‐Ando, K., Kagawa‐Nagamura, Y., Kobayashi, C., Ikegaya, Y., & Nakai, J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051286 · Cited by 267
Coupling of Neural Activity to Blood Flow in Olfactory Glomeruli Is Mediated by Astrocytic Pathways
Petzold, G. C., Albeanu, D. F., Sato, T. F., & Murthy, V. N. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.029 · Cited by 263
Simultaneous BOLD fMRI and fiber-optic calcium recording in rat neocortex
Schulz, K., Sydekum, E., Krueppel, R., Engelbrecht, C. J., Schlegel, F., Schroeter, A., Rudin, M., & Helmchen, F. (2012) · Nature Methods · doi:10.1038/nmeth.2013 · Cited by 245
Functional Fluorescent Ca2+ Indicator Proteins in Transgenic Mice under TET Control
Hasan, M. T., Friedrich, R. W., Euler, T., Larkum, M. E., Giese, G., Both, M., Duebel, J., Waters, J., Bujard, H., Griesbeck, O., et al. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020163 · Cited by 242
Astrocyte-Mediated Distributed Plasticity at Hypothalamic Glutamate Synapses
Gordon, G. R., Iremonger, K. J., Kantevari, S., Ellis‐Davies, G. C. R., MacVicar, B. A., & Bains, J. S. (2009) · Neuron · doi:10.1016/j.neuron.2009.10.021 · Cited by 234
Aguado, F., Espinosa‐Parrilla, J. F., Carmona, M. A., & Soriano, E. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-21-09430.2002 · Cited by 230
Astrocyte-mediated activation of neuronal kainate receptors
Liu, Q.-S., Xu, Q., Arcuino, G., Kang, J., & Nedergaard, M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0306731101 · Cited by 230
Imaging Neural Activity Using Thy1-GCaMP Transgenic Mice
Chen, Q., Cichon, J., Wang, W., Qiu, L., Lee, S.-J. R., Campbell, N. R., DeStefino, N. R., Goard, M. J., Fu, Z., Yasuda, R., et al. (2012) · Neuron · doi:10.1016/j.neuron.2012.07.011 · Cited by 222
Astrocytic regulation of cortical UP states
Poskanzer, K. E., & Yuste, R. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1112378108 · Cited by 221
Adrenergic calcium signaling in astrocyte networks within the hippocampal slice
Duffy, S. N., & MacVicar, B. A. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-08-05535.1995 · Cited by 216
Reorganization of cortical population activity imaged throughout long-term sensory deprivation
Margolis, D. J., Lütcke, H., Schulz, K., Haiss, F., Weber, B., Kügler, S., Hasan, M. T., & Helmchen, F. (2012) · Nature Neuroscience · doi:10.1038/nn.3240 · Cited by 203
Nucleus basalis-enabled stimulus-specific plasticity in the visual cortex is mediated by astrocytes
Chen, N., 杉原, 弘., Sharma, J., Perea, G., Petravicz, J., Le, C., & Sur, M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1206557109 · Cited by 186
Smith, I. F., & Parker, I. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0810799106 · Cited by 183
Imaging Neuronal Activity with Genetically Encoded Calcium IndicatorsPreprint
Tian, L., Hires, S. A., & Looger, L. L. (2012) · Cold Spring Harbor Protocols · doi:10.1101/pdb.top069609 · Cited by 175
Fast GCaMPs for improved tracking of neuronal activity
Sun, X. R., Badura, A., Pacheco, D. A., Lynch, L. A., Schneider, E. R., Taylor, M. P., Hogue, I. B., Enquist, L. W., Murthy, M., & Wang, S. S. ‐. (2013) · Nature Communications · doi:10.1038/ncomms3170 · Cited by 140
Agonist Binding and Gq-Stimulating Activities of the Purified Human P2Y1 Receptor
Waldo, G. L., & Harden, T. K. (2004) · Molecular Pharmacology · doi:10.1124/mol.65.2.426 · Cited by 133
Astrocytic Ca2+ signals are required for the functional integrity of tripartite synapses
Tanaka, M., Shih, P.-Y., Gomi, H., Yoshida, T., Nakai, J., Ando, R., Furuichi, T., Mikoshiba, K., Semyanov, A., & Itohara, S. (2013) · Molecular Brain · doi:10.1186/1756-6606-6-6 · Cited by 127
Calcium indicator loading of neurons using single-cell electroporation
Nevian, T., & Helmchen, F. (2007) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-007-0234-2 · Cited by 126
GABA uptake-dependent Ca 2+ signaling in developing olfactory bulb astrocytes
Doengi, M., Hirnet, D., Coulon, P., Pape, H., Deitmer, J. W., & Lohr, C. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809513106 · Cited by 125
Na + /Ca 2+ exchanger modulates kainate‐triggered Ca 2+ signaling in Bergmann glial cells in situ
Kirischuk, S., Kettenmann, H., & Verkhratsky, A. (1997) · The FASEB Journal · doi:10.1096/fasebj.11.7.9212080 · Cited by 124
Bergmann glia modulate cerebellar Purkinje cell bistability via Ca 2+ -dependent K + uptake
Wang, F., Xu, Q., Wang, W., Takano, T., & Nedergaard, M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120380109 · Cited by 120
The tripartite synapse Glia in Synaptic Transmission
Jellinger, K. A. (2003) · European Journal of Neurology · doi:10.1046/j.1468-1331.2003.05568.x · Cited by 116
Marchaland, J., Calì, C., Voglmaier, S. M., Li, H., Regazzi, R., Edwards, R. H., & Bezzi, P. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0040-08.2008 · Cited by 113
Steady or changing? Long-term monitoring of neuronal population activity
Lütcke, H., Margolis, D. J., & Helmchen, F. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2013.03.008 · Cited by 112
Cannabinoid receptor binding and agonist activity of amides and esters of arachidonic acid.
PINTO, J. C., Potié, F., Rice, K. C., Boring, D. L., Johnson, M. R., Evans, D. M., Wilken, G. H., Cantrell, C. H., & Howlett, A. C. (1994) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09729-9 · Cited by 109
Nash, M. S., Schell, M. J., Atkinson, P. J., Johnston, N. R., Nahorski, S. R., & Challiss, R. A. J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205622200 · Cited by 104
The tripartite synapse: glia in synaptic transmission
Volterra, A., Magistretti, P. J., & Haydon, P. G. (2002) · Infoscience (Ecole Polytechnique Fédérale de Lausanne) · Cited by 103
Self-citationPittà, M. D., Volman, V., Berry, H., Parpura, V., Volterra, A., & Ben‐Jacob, E. (2012) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2012.00098 · Cited by 96
Self-citationQuantitative two-photon Ca2+ imaging via fluorescence lifetime analysis
Wilms, C. D., Schmidt, H., & Eilers, J. (2006) · Cell Calcium · doi:10.1016/j.ceca.2006.03.006 · Cited by 81
Nitric Oxide Signals Parallel Fiber Activity to Bergmann Glial Cells in the Mouse Cerebellar Slice
Matyash, V., Filippov, V., Mohrhagen, K., & Kettenmann, H. (2001) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2001.1047 · Cited by 69
Neuroscience: Settling the great glia debate
Smith, K. (2010) · Nature · doi:10.1038/468160a · Cited by 68
Astrocytes as Regulators of Synaptic Function
Rusakov, D. A., Zheng, K., & Henneberger, C. (2011) · The Neuroscientist · doi:10.1177/1073858410387304 · Cited by 67
Glial Cells Decipher Synaptic Competition at the Mammalian Neuromuscular Junction
Darabid, H., Arbour, D., & Robitaille, R. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2935-12.2013 · Cited by 67
Arizono, M., Bannai, H., Nakamura, K. M., Niwa, F., Enomoto, M., Matsuura, T., Miyamoto, A., Sherwood, M. W., Nakamura, T., & Mikoshiba, K. (2012) · Science Signaling · doi:10.1126/scisignal.2002498 · Cited by 67
Genetic approaches to study glial cells in the rodent brain
Pfrieger, F. W., & Ślęzak, M. (2011) · Glia · doi:10.1002/glia.22283 · Cited by 47
Quantitative comparison of novel GCaMP-type genetically encoded Ca2+ indicators in mammalian neurons
Yamada, Y., & Mikoshiba, K. (2012) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2012.00041 · Cited by 45
Honsek, S. D., Walz, C., Kafitz, K. W., & Rose, C. R. (2012) · Hippocampus · doi:10.1002/hipo.20843 · Cited by 42
Matsui, K., & Jahr, C. E. (2006) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2006.04.001 · Cited by 26
Computer applications in water supply, vol. 1
Coulbeck, B., & Orr, C. (1988) · John Wiley & Sons, Inc. eBooks · Cited by 16
Two-Color STED Imaging of Synapses in Living Brain Slices
Tønnesen, J., & Nägerl, U. V. (2012) · Methods in molecular biology · doi:10.1007/978-1-62703-137-0_5 · Cited by 12
Calcium sensors reach new heights
Pastrana, É. (2013) · Nature Methods · doi:10.1038/nmeth.2628 · Cited by 3
Nolte (2001) · doi:10.1002/1098-1136(20010101)33:1
Research works printed but not linked: 1
- Volterra, A. in Neuroglia (eds Kettenmann, H. & Ransom, B. R.) 816–823 (Oxford Univ. Press, 2013).
Cited by
Sorted by citations
Verkhratsky, A., & Nedergaard, M. (2018) · Physiological Reviews · doi:10.1152/physrev.00042.2016 · Cited by 1,678
Astrocyte calcium signaling: the third wave
Bazargani, N., & Attwell, D. (2016) · Nature Neuroscience · doi:10.1038/nn.4201 · Cited by 998
Astrocyte function from information processing to cognition and cognitive impairment
Santello, M., Toni, N., & Volterra, A. (2019) · Nature Neuroscience · doi:10.1038/s41593-018-0325-8 · Cited by 737
Self-citationFunction and therapeutic value of astrocytes in neurological diseases
Lee, H.-G., Wheeler, M. A., & Quintana, F. J. (2022) · Nature Reviews Drug Discovery · doi:10.1038/s41573-022-00390-x · Cited by 662
Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration
Patani, R., Hardingham, G. E., & Liddelow, S. A. (2023) · Nature Reviews Neurology · doi:10.1038/s41582-023-00822-1 · Cited by 531
Metadata
- Authors
- Volterra, A., Liaudet, N., & Savtchouk, I.
- Affiliations
- University of Lausanne (CH)
- Corresponding author
- Volterra, Andrea
- Venue
- Nature Reviews Neuroscience
- Published
- 2014-04-17
- Volume
- 15
- Issue
- 5
- Pages
- 327-335
- ISSN
- 1471-003X (ISSN-L)
- 1471-0048
- OpenAlex
- W1972077052
- Cited by
- 446
- References
- 117
- Citations by year
- 2026: 15 · 2025: 32 · 2024: 27 · 2023: 32 · 2022: 27 · 2021: 43 · 2020: 44 · 2019: 52 · 2018: 50 · 2017: 37 · 2016: 38 · 2015: 43 · 2014: 6
- FWCI
- 4.66
- Type
- journal article
- Language
- en
- Open access
- green
- iris.unil.ch
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature reviews. Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- IRIS (submittedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
- SERVAL (Université de Lausanne) (submittedVersion, other-oa)
- Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (140999, 31003A)
- FP7 Ideas: European Research Council (340368)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- astrocytes, calcium signaling, calcium dynamics, synaptic function, brain information processing, astrocyte-neuron interaction, brain integration
- MeSH terms
- Animals, Astrocytes, Brain, Calcium, Humans, Synapses, Calcium Signaling
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
