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Cited by 272

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

Open access
Polikanov, Yury S, Melnikov, Sergey V, Söll, Dieter, Steitz, Thomas A·2015·Nature Structural & Molecular Biology

Abstract

We report crystal structures of the Thermus thermophilus ribosome at 2.3- to 2.5-Å resolution, which have enabled modeling of rRNA modifications. The structures reveal contacts of modified nucleotides with mRNA and tRNAs or protein pY, and contacts within the ribosome interior stabilizing the functional fold of rRNA. Our work provides a resource to explore the roles of rRNA modifications and yields a more comprehensive atomic model of a bacterial ribosome.

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Metadata

Authors
Polikanov, Y. S., Melnikov, S. V., Söll, D., & Steitz, T. A.
Venue
Nature Structural & Molecular Biology
Published
2015-03-16
Volume
22
Issue
4
Pages
342-344
ISSN
  • 1545-9985 (ISSN-L)
  • 1545-9993
OpenAlex
W2129874158
Cited by
272
References
3
FWCI
8.62
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly. https://app.cochat.ai/papers/10.1038/nsmb.2992
The paper
Polikanov, Y. S., Melnikov, S. V., Söll, D., & Steitz, T. A. (2015). Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly. Nature Structural & Molecular Biology. https://doi.org/10.1038/nsmb.2992

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.