The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Effect of Diet and Exercise, Alone or Combined, on Weight and Body Composition in Overweight‐to‐Obese Postmenopausal Women
Open accessAbstract
Lifestyle interventions for weight loss are the cornerstone of obesity therapy, yet their optimal design is debated. This is particularly true for postmenopausal women; a population with a high prevalence of obesity yet toward whom fewer studies are targeted. We conducted a year‐long, 4‐arm randomized trial among 439 overweight‐to‐obese postmenopausal sedentary women to determine the effects of a calorie‐reduced, low‐fat diet (D), a moderate‐intensity, facility‐based aerobic exercise program (E), or the combination of both interventions (D+E), vs. a no‐lifestyle‐change control (C) on change in body weight and composition. The group‐based dietary intervention had a weight‐reduction goal of ≥10%, and the exercise intervention consisted of a gradual escalation to 45‐min aerobic exercise 5 day/week. Participants were predominantly non‐Hispanic whites (85%) with a mean age of 58.0 ± 5.0 years, a mean BMI of 30.9 ± 4.0 kg/m 2 and an average of 47.8 ± 4.4% body fat. Baseline and 12‐month weight and adiposity measures were obtained by staff blinded to participants' intervention assignment. Three hundred and ninety nine women completed the trial (91% retention). Using an intention‐to‐treat analysis, average weight loss at 12 months was −8.5% for the D group (P < 0.0001 vs. C), −2.4% for the E group (P = 0.03 vs. C), and −10.8% for the D+E group (P < 0.0001 vs. C), whereas the C group experienced a nonsignificant −0.8% decrease. BMI, waist circumference, and % body fat were also similarly reduced. Among postmenopausal women, lifestyle‐change involving diet, exercise, or both combined over 1 year improves body weight and adiposity, with the greatest change arising from the combined intervention.
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Cites
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
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Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet
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“Providing group-based nutrition education along with exercise likely outweighs the costs of health consequences that come from untreated obesity, assuming these changes can be sustained over the long-term (43,44).”
BackgroundThe Look AHEAD Study: A Description of the Lifestyle Intervention and the Evidence Supporting It
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One-year weight losses in the Look AHEAD study: factors associated with success
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Cited by
Obesity and Cancer: A Current Overview of Epidemiology, Pathogenesis, Outcomes, and Management
Pati, S., Irfan, W., Jameel, A., Ahmed, S., & Shahid, R. K. (2023) · Cancers · doi:10.3390/cancers15020485 · Cited by 677
The Effects of Exercise and Physical Activity on Weight Loss and Maintenance
Swift, D. L., McGee, J. E., Earnest, C. P., Carlisle, E., Nygard, M., & Johannsen, N. M. (2018) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2018.07.014 · Cited by 536
Obesity, adiposity, and dyslipidemia: a consensus statement from the National Lipid Association
Bays, H. E., Toth, P. P., Kris-Etherton, P. M., Abate, N., Aronne, L. J., Brown, W. V., Gonzalez-Campoy, J. M., Jones, S. R., Kumar, R., La Forge, R., et al. (2013) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2013.04.001 · Cited by 521
Ma, C., Avenell, A., Bolland, M., Hudson, J., Stewart, F., Robertson, C., Sharma, P., Fraser, C., & MacLennan, G. (2017) · BMJ · doi:10.1136/bmj.j4849 · Cited by 464
Effects of intermittent fasting on body composition and clinical health markers in humans
Tinsley, G. M., & La Bounty, P. M. (2015) · Nutrition Reviews · doi:10.1093/nutrit/nuv041 · Cited by 382
Metadata
- Authors
- Foster‐Schubert, K. E., Alfano, C. M., Duggan, C. R., Xiao, L., Campbell, K. L., Kong, A., Bain, C. E., Wang, C., Blackburn, G. L., & McTiernan, A.
- Venue
- Obesity
- Publisher
- Wiley
- Published
- 2012-08
- Volume
- 20
- Issue
- 8
- Pages
- 1628-1638
- ISSN
- 1930-7381 (ISSN-L)
- 1930-739X
- OpenAlex
- W2002336468
- Cited by
- 452
- References
- 11
- FWCI
- 22.64
- Type
- journal article
- Language
- en
- Open access
- green
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- Foster‐Schubert, K. E., Alfano, C. M., Duggan, C. R., Xiao, L., Campbell, K. L., Kong, A., Bain, C. E., Wang, C., Blackburn, G. L., & McTiernan, A. (2012). Effect of Diet and Exercise, Alone or Combined, on Weight and Body Composition in Overweight‐to‐Obese Postmenopausal Women. Obesity. https://doi.org/10.1038/oby.2011.76
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