SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production
Bell, E L, Emerling, B M, Ricoult, S J H, Guarente, L·2011·Oncogene
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Items 201–300 of 438
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- Seeding for sirtuins: microseed matrix seeding to obtain crystals of human Sirt3 and Sirt2 suitable for soakingTobias Rumpf, S. Gerhardt, Oliver Einsle, Manfred Jung · 2015 · Acta Crystallographica Section F Structural Biology Communications
- Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of SIRT3 Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive PhenotypeXianghui Zou, Cesar Augusto Santa-Maria, Joseph O’Brien, David R. Gius, Yueming Zhu · 2016 · Antioxidants and Redox Signaling
- NAD+ in Cancer Prevention and Treatment: Pros and ConsBorut Poljšak · 2016 · Journal of Clinical & Experimental Oncology
- Mitochondrial Redox Metabolism: The Epicenter of Metabolism during Cancer ProgressionFeroza K. Choudhury · 2021 · Antioxidants
- The Many Faces of Sirtuins: Sirtuins and the Warburg effectLeonard Guarente · 2014 · Nature Medicine
- Cellular consequences of oxidative stress in riboflavin responsive multiple acyl-CoA dehydrogenation deficiency patient fibroblastsNanna Cornelius, Thomas J. Corydon, Nanna Vendelboe Gregersen, Rikke Katrine Jentoft Olsen · 2014 · Human Molecular Genetics
- Potential suppression of the high glucose and insulin-induced retinal neovascularization by Sirtuin 3 in the human retinal endothelial cellsXinbang Mao, Zhipeng You, Chen Wu, Jun Huang · 2016 · Biochemical and Biophysical Research Communications
- Role of Sirtuins in Tumor AngiogenesisLincy Edatt, Aswini Poyyakkara, Grace R. Raji, Vishnu Ramachandran, Sarojini Sharath Shankar, V.B. Sameer Kumar · 2020 · Frontiers in Oncology
- Gastrodin attenuates microglia activation through renin-angiotensin system and Sirtuin3 pathwayShun-Jin Liu, Xiaoyu Liu, Jinghui Li, Jing Guo, Fan Li, Yang Gui, Xiu-Hua Li, Li Yang, Chunyun Wu, Yun Yuan et al. · 2018 · Neurochemistry International
- Metabolic reprogramming: a bridge between aging and tumorigenesisDrapela, Stanislav, Ilter, Didem, Gomes, Ana P. · 2022 · Molecular Oncology
- Rewiring of mitochondrial metabolism in therapy-resistant cancers: permanent and plastic adaptationsKatherine E. Pendleton, Karen Wang, Gloria Vittone Echeverria · 2023 · Frontiers in Cell and Developmental Biology
- SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunctionPing He, Zhuoming Li, Zhongbao Yue, Hui Gao, Guoshuai Feng, Panxia Wang, Yi Huang, Wenwei Luo, Huiqi Hong, Liying Liang et al. · 2017 · Molecular and Cellular Endocrinology
- Metabolic Rewiring in Response to Biguanides Is Mediated by mROS/HIF-1a in Malignant LymphocytesHamidullah Khan, Ashish Anshu, A. Krishna Prasad, Sushmita Roy, Justin J. Jeffery, Wasakorn Kittipongdaja, David T. Yang, Stefan M. Schieke · 2019 · Cell Reports
- Role of SIRT3 in the regulation of redox balance during oral carcinogenesisI‐Chieh Chen, Wei‐Fan Chiang, Shyun-Yeu Liu, Pei‐Fen Chen, Hung‐Che Chiang · 2013 · Molecular Cancer
- Regulation of SIRT3 signal related metabolic reprogramming in gastric cancer byHelicobacter pylorioncoprotein CagADoyeon Lee, Dawoon Jung, Sung Sook Yu, Yeo Song Lee, Beom Ku Choi, Yong Chan Lee · 2017 · Oncotarget
- Chemical and Physiological Features of Mitochondrial AcylationAlison Epstein Ringel, Sarah A. Tucker, Marcia C. Haigis · 2018 · Molecular Cell
- The role of mammalian sirtuins in cancer metabolismCarlos Sebastián, Raúl Mostoslavsky · 2015 · Seminars in Cell and Developmental Biology
- SIRT3 Expression as a Biomarker for Better Prognosis in Gastric CancerKuo‐Hung Huang, Chia‐Chi Hsu, Wen‐Liang Fang, Chin‐Wen Chi, Ming‐Ta Sung, Hwa-Li Kao, Anna Fen–Yau Li, Pen‐Hui Yin, Muh‐Hwa Yang, Hsin‐Chen Lee · 2013 · World Journal of Surgery
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- SIRT3 is correlated with the malignancy of non-small cell lung cancerYanlu Xiong, Mingxing Wang, Jinbo Zhao, Lei Wang, Xiaofei Li, Zhipei Zhang, Lintao Jia, Yong Han · 2017 · International Journal of Oncology
- Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3Karina N. Gonzalez Herrera, Elma Zaganjor, Yoshinori Ishikawa, Jessica B. Spinelli, Haejin Yoon, Jia‐Ren Lin, F. Kyle Satterstrom, Alison Epstein Ringel, Stacy Mulei, Amanda Souza et al. · 2018 · Cell Reports
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- Sirtuins in metabolism, stemness and differentiationMarcelo Correia, Tânia Perestrelo, Ana Sofia Rodrigues, Marcelo F. Ribeiro, Sandro L. Pereira, Maria Inês Sousa, João Ramalho‐Santos · 2016 · Biochimica et Biophysica Acta (BBA) - General Subjects
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- The role of sirtuins in mitochondrial function and doxorubicin-induced cardiac dysfunctionVernon Wayne Dolinsky · 2017 · Biological Chemistry
- Dual Deletion of the Sirtuins SIRT2 and SIRT3 Impacts on Metabolism and Inflammatory Responses of Macrophages and Protects From EndotoxemiaTytti Heinonen, Eleonora Ciarlo, Ersilia Rigoni, Jean Regina, Didier Le Roy, Thierry Roger · 2019 · Frontiers in Immunology
- Increased mitochondrial content and function by resveratrol and select flavonoids protects against benzo[a]pyrene-induced bioenergetic dysfunction and ROS generation in a cell model of neoplastic transformationKosar Omidian, Hossein Rafiei, Brian Bandy · 2020 · Free Radical Biology and Medicine
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- Role of SIRT3 in Angiotensin II-induced human umbilical vein endothelial cells dysfunctionLiu, Hui, Chen, Tongshuai, Li, Na, Wang, Shujian, Bu, Peili · 2015 · BMC Cardiovascular Disorders
- TGR5 deficiency aggravates hepatic ischemic/reperfusion injury via inhibiting SIRT3/FOXO3/HIF-1ɑ pathwayQi Wang, Wei Song, Lei Li, Jiannan Qiu, Shun Zhou, Chengyu Shi, Yong Shi, Haoming Zhou, Ling Lü · 2020 · Cell Death Discovery
- Mitochondrial Sirtuins as Therapeutic Targets for Age-Related DisordersJuliann Shih, Gizem Dönmez · 2013 · Genes & Cancer
- Small-molecule inhibitors at the PSD-95/nNOS interface attenuate MPP+-induced neuronal injury through Sirt3 mediated inhibition of mitochondrial dysfunctionWei Ming Hu, Lai-Shun Guan, Xingbo Dang, Pengyu Ren, Yuelin Zhang · 2014 · Neurochemistry International
- Introduction: Sirtuins in Aging and DiseasesLeonard Guarente · 2013 · Methods in molecular biology
- Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cellsDelu Dong, Yuan Dong, Jiaying Fu, Shengyao Lu, Chunli Yuan, Meihui Xia, Liankun Sun · 2020 · Life Sciences
- Sirtuin Deacetylases as Therapeutic Targets in the Nervous SystemBrett C. Langley, Anthony A. Sauve · 2013 · Neurotherapeutics
- SIRT3 expression in hepatocellular carcinoma and its impact on proliferation and invasion of hepatoma cellsBo Zhang, Lei Qin, Cui-Jie Zhou, Ye-Lu Liu, Haixin Qian, Songbing He · 2013 · Asian Pacific Journal of Tropical Medicine
- SIRT3 mediates decrease of oxidative damage and prevention of ageing in porcine fetal fibroblastsXiaoxian Xie, Liangliang Wang, Binggong Zhao, Yangyang Chen, Jiaqi Li · 2017 · Life Sciences
- Glutamine, Glucose and other Fuels for CancerMaría Victoria Ruiz-Pérez, Francisca Sánchez‐Jiménez, Francisco José Alonso, Juan Segura, Javier Márquez, Miguel Ángel Medina · 2014 · Current Pharmaceutical Design
- Cancer‐associated fibroblast‐secreted miR ‐421 promotes pancreatic cancer by regulating the SIRT3 / H3K9Ac / HIF ‐1α axisBin Zhou, Jing‐Hao Lei, Qiang Wang, Teng‐Fei Qu, Lichao Cha, Hanxiang Zhan, Shanglong Liu, Xiao Hu, Chuandong Sun, Weidong Guo et al. · 2022 · The Kaohsiung Journal of Medical Sciences
- Estradiol via estrogen receptor beta influences ROS levels through the transcriptional regulation of SIRT3 in human seminoma TCam-2 cellsSalvatore Panza, Marta Santoro, Francesca De Amicis, Catia Morelli, Valentina Passarelli, Patrizia D’Aquila, Francesca Giordano, Erika Cione, Giuseppe Passarino, Dina Bellizzi et al. · 2017 · Tumor Biology
- Antioxidant and Cardioprotective Effects of EPA on Early Low-Severity Sepsis through UCP3 and SIRT3 Upholding of the Mitochondrial Redox PotentialThibault Léger, Kasra Azarnoush, Amidou Sissou Traoré, L. Cassagnes, Jean‐Paul Rigaudière, Chrystèle Jouve, Guilhem Pagés, Damien Bouvier, Vincent Sapin, Bruno Pereira et al. · 2019 · Oxidative Medicine and Cellular Longevity
- Effects of Sirt3‑autophagy and resveratrol activation on myocardial hypertrophy and energy metabolismHai‐Ning Wang, Jilin Li, Tan Xu, Huaiqi Yao, Guihua Chen, Jing Hu · 2020 · Molecular Medicine Reports
- Sirtuin 3 Deficiency Does Not Augment Hypoxia-Induced Pulmonary HypertensionGregory B. Waypa, Scott W. Osborne, Jeremy D. Marks, Sara K. Berkelhamer, Jyothisri Kondapalli, Paul T. Schumacker · 2013 · American Journal of Respiratory Cell and Molecular Biology
- The evaluation of potent antitumor activities of shikonin coumarin-carboxylic acid, PMMB232 through HIF-1α-mediated apoptosisHongwei Han, Chao-Sai Zheng, So Jeong Chu, Wenxue Sun, Lujing Han, Rongwu Yang, Jinliang Qi, Guihua Lu, Xiaoming Wang, Yonghua Yang · 2017 · Biomedicine & Pharmacotherapy
- Role of SIRT-3, p-mTOR and HIF-1α in Hepatocellular Carcinoma Patients Affected by Metabolic Dysfunctions and in Chronic Treatment with MetforminSerena De Matteis, Emanuela Scarpi, Anna Maria Granato, Umberto Vespasiani Gentilucci, Giuliano La Barba, Francesco Giuseppe Foschi, Erika Bandini, Martina Ghetti, Giorgia Marisi, Paola Cravero et al. · 2019 · International Journal of Molecular Sciences
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- Sirtuin biology and relevance to diabetes treatmentXiaocheng Charlie Dong · 2012 · Diabetes Management
- PLGA‐PNIPAM Microspheres Loaded with the Gastrointestinal Nutrient NaB Ameliorate Cardiac Dysfunction by Activating Sirt3 in Acute Myocardial InfarctionPanke Cheng, Wen Zeng, Li Li, Da Huo, Lingqing Zeng, Ju Tan, Jingting Zhou, Jiansen Sun, Ge Liu, Yanzhao Li et al. · 2016 · Advanced Science
- PX-12-induced HeLa cell death is associated with oxidative stress and GSH depletionHye Rim Shin, Bo Ra You, Woo Hyun Park · 2013 · Oncology Letters
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- Mitochondrial sirtuin 3 and various cell death modalitiesMaria A. Yapryntseva, Polina V. Maximchik, Boris Zhivotovsky, Vladimir G. Gogvadze · 2022 · Frontiers in Cell and Developmental Biology
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- NAD metabolism in aging and cancerJohn W. R. Kincaid, Nathan A. Berger · 2020 · Experimental Biology and Medicine
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- Mitochondrial Acetylation and Genetic Models of Parkinson's DiseaseGeorg W. J. Auburger, Suzana Gispert, Marina Jendrach · 2014 · Progress in molecular biology and translational science
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- Alterations in Sod2-Induced Oxidative Stress Affect Endocrine Cancer ProgressionAmruta Ashtekar, Danielle J. Huk, Alexa Magner, Krista M. D. La Perle, Laura Boucai, Lawrence Steven Kirschner · 2018 · The Journal of Clinical Endocrinology & Metabolism
- The Complex Interplay between Metabolic Reprogramming and Epigenetic Alterations in Renal Cell CarcinomaAna Lameirinhas, Vera Miranda‐Gonçalves, Rui Henrique, Cármen Jerónimo · 2019 · Genes
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