SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production

Bell, E L, Emerling, B M, Ricoult, S J H, Guarente, L·2011·Oncogene

Cited by (438)

Items 101–200 of 438

  1. Acute hypoxia produces a superoxide burst in cells
    Pablo Hernansanz‐Agustín, Alicia Izquierdo-Álvarez, Francisco J. Sánchez-Gómez, Elena M. Ramos, Tamara Villa-Piña, Santiago Lamas, Anna Y. Bogdanova, Antonio Martı́nez-Ruiz · 2014 · Free Radical Biology and Medicine
  2. Sirtuin deacylases: a molecular link between metabolism and immunity
    Nicolas Preyat, Oberdan Léo · 2013 · Journal of Leukocyte Biology
  3. Sirtuins, metabolism, and DNA repair
    Jee-Eun Choi, Raúl Mostoslavsky · 2014 · Current Opinion in Genetics & Development
  4. Metabolic regulation by SIRT3: implications for tumorigenesis
    Lydia W.S. Finley, Marcia C. Haigis · 2012 · Trends in Molecular Medicine
  5. The Roles of Sirtuin Family Proteins in Cancer Progression
    Erhu Zhao, Jianbing Hou, Xiaoxue Ke, Muhammad Nadeem Abbas, Saima Kausar, Lei Zhang, Hongjuan Cui · 2019 · Cancers
  6. Metabolism and Epigenetic Interplay in Cancer: Regulation and Putative Therapeutic Targets
    Vera Miranda‐Gonçalves, Ana Lameirinhas, Rui Henrique, Cármen Jerónimo · 2018 · Frontiers in Genetics
  7. Chromatin as an oxygen sensor and active player in the hypoxia response
    Andrew Melvin, Sónia Rocha · 2011 · Cellular Signalling
  8. SIRT3 interactions with FOXO3 acetylation, phosphorylation and ubiquitinylation mediate endothelial cell responses to hypoxia
    Tseng, Anne H.-H., Wu, Li-Hong, Shieh, Shyan-Shu, Wang, Danny Ling · 2014 · Biochemical Journal
  9. Emerging role of ferroptosis in breast cancer: New dawn for overcoming tumor progression
    Shiyao Sui, Shouping Xu, Da Pang · 2021 · Pharmacology & Therapeutics
  10. The roles of sirtuins family in cell metabolism during tumor development
    Shunqin Zhu, Zhen Dong, Xiaoxue Ke, Jianbing Hou, Erhu Zhao, Kui Zhang, Feng Wang, Liqun Yang, Zhonghuai Xiang, Hongjuan Cui · 2018 · Seminars in Cancer Biology
  11. A nexus for cellular homeostasis: the interplay between metabolic and signal transduction pathways
    Gomes, Ana P, Blenis, John · 2015 · Current Opinion in Biotechnology
  12. Mitochondrial sirtuins: Emerging roles in metabolic regulations, energy homeostasis and diseases
    Priyanka Parihar, Isha Solanki, Mohammad Lukman Mansuri, Mordhwaj S. Parihar · 2014 · Experimental Gerontology
  13. Mitochondrial toxicity of tobacco smoke and air pollution
    Jessica L. Fetterman, Melissa J. Sammy, Scott W. Ballinger · 2017 · Toxicology
  14. Hypoxia-inducible factor as a therapeutic target for cardioprotection
    Sang‐Ging Ong, Derek John Hausenloy · 2012 · Pharmacology & Therapeutics
  15. SIRT1, metabolism and cancer
    John R. P. Knight, Jo Milner · 2011 · Current Opinion in Oncology
  16. Detection of mitochondria-generated reactive oxygen species in cells using multiple probes and methods: Potentials, pitfalls, and the future
    Gang Cheng, Monika Zielonka, Brian P. Dranka, Suresh N. Kumar, Charles R. Myers, Brian Bennett, Alexander M. Garces, Luiz Gabriel Dias Duarte Machado, David Thiébaut, Olivier Ouari et al. · 2018 · Journal of Biological Chemistry
  17. Epigenetic modifications in colorectal cancer: Molecular insights and therapeutic challenges
    George Vaiopoulos, Kalliopi Ch. Athanasoula, Athanasios G. Papavassiliou · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  18. The effects of aging, physical training, and a single bout of exercise on mitochondrial protein expression in human skeletal muscle
    Bori, Zoltan, Zhao, Zhongfu, Koltai, Erika, Fatouros, Ioannis G., Jamurtas, Athanasios Z., Douroudos, Ioannis I., Terzis, Gerasimos, Chatzinikolaou, Athanasios, Sovatzidis, Apostolos, Draganidis, Dimitrios et al. · 2012 · Experimental Gerontology
  19. Sirt3, Mitochondrial ROS, Ageing, and Carcinogenesis
    Seong‐Hoon Park, Özkan Özden, Haiyan Jiang, Yong I. Cha, J. Daniel Pennington, Nükhet Aykin‐Burns, Douglas R. Spitz, David R. Gius, Hyunseok Kim · 2011 · International Journal of Molecular Sciences
  20. Global Profiling of Metabolic Adaptation to Hypoxic Stress in Human Glioblastoma Cells
    Paulina Kucharzewska, Helena C. Christianson, Mattias Belting · 2015 · PLoS ONE
  21. High-altitude hypoxia induced reactive oxygen species generation, signaling, and mitigation approaches
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  22. Sirtuins' control of autophagy and mitophagy in cancer
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  23. Sirt3 inhibits hepatocellular carcinoma cell growth through reducing Mdm2-mediated p53 degradation
    Yuanyuan Zhang, Liming Zhou · 2012 · Biochemical and Biophysical Research Communications
  24. Nutrient Sensing and the Oxidative Stress Response
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  25. SIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells
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  26. NQO1 in protection against oxidative stress
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  27. Arsenic Induces Insulin Resistance in Mouse Adipocytes and Myotubes Via Oxidative Stress-Regulated Mitochondrial Sirt3-FOXO3a Signaling Pathway
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  28. Hypoxic preconditioning combined with curcumin promotes cell survival and mitochondrial quality of bone marrow mesenchymal stem cells, and accelerates cutaneous wound healing via PGC-1α/SIRT3/HIF-1α signaling
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  29. Loss of SIRT3 Provides Growth Advantage for B Cell Malignancies
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  30. The role of sirtuins in modulating redox stressors
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  31. Molecular mechanisms of oxidative stress in stroke and cancer
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    L Wei, Yuxin Zhou, C Qiao, T Ni, Zhihua Li, Qidong You, Qinglong Guo, Na Lu · 2015 · Cell Death and Disease
  33. SIRT3: As Simple As It Seems?
    David B. Lombard, Bernadette M. M. Zwaans · 2013 · Gerontology
  34. Metformin and insulin impact on clinical outcome in patients with advanced hepatocellular carcinoma receiving sorafenib: Validation study and biological rationale
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  38. Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3
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  40. The reduced concentration of citrate in cancer cells: An indicator of cancer aggressiveness and a possible therapeutic target
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  41. SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis.
    Seong‐Hoon Park, Yuming Zhu, Özkan Özden, Hyun Seok Kim, Haiyan Jiang, Chu‐Xia Deng, David R. Gius, Athanassios Vassilopoulos · 2012 · PubMed
  42. Sirtuins and the Metabolic Hurdles in Cancer
    Natalie J. German, Marcia C. Haigis · 2015 · Current Biology
  43. Emerging role of SIRT3 in mitochondrial dysfunction and cardiovascular diseases
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  44. Subcellular compartmentalization of NAD+ and its role in cancer: A sereNADe of metabolic melodies
    Yi Zhu, Jiaqi Liu, Joun Park, Priyamvada Rai, Rong Grace Zhai · 2019 · Pharmacology & Therapeutics
  45. Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming
    Bernadette M. M. Zwaans, David B. Lombard · 2014 · Disease Models & Mechanisms
  46. Mitochondrial Redox Signaling and Tumor Progression
    Yuxin Chen, Haiqing Zhang, Huanjiao Jenny Zhou, Weidong Ji, Min Wang · 2016 · Cancers
  47. Epigenetic regulation of hypoxia‐responsive gene expression: Focusing on chromatin and DNA modifications
    Ya‐Ping Tsai, Kou‐Juey Wu · 2013 · International Journal of Cancer
  48. Melatonin inhibits Warburg-dependent cancer by redirecting glucose oxidation to the mitochondria: a mechanistic hypothesis
    Russel Joseph Reiter, Ramaswamy Sharma, Qiang Ma, Sergio Rosales‐Corral, Luiz Gustavo de Almeida Chuffa · 2020 · Cellular and Molecular Life Sciences
  49. A comprehensive review of Sirtuins: With a major focus on redox homeostasis and metabolism
    Shahab Shahgaldi, Fatemeh Rezaei Kahmini · 2021 · Life Sciences
  50. SIRT3 a Major Player in Attenuation of Hepatic Ischemia‐Reperfusion Injury by Reducing ROS via Its Downstream Mediators: SOD2, CYP‐D, and HIF‐1α
    Gaurav Katwal, Dilip Baral, Xiaoli Fan, Weiyang He, Xinjiang Zhang, Ling Li, Yan Xiong, Qifa Ye, Yanfeng Wang · 2018 · Oxidative Medicine and Cellular Longevity
  51. Redox signalling and mitochondrial stress responses; lessons from inborn errors of metabolism
    Rikke Katrine Jentoft Olsen, Nanna Cornelius, Niels Gregersen · 2015 · Journal of Inherited Metabolic Disease
  52. Sirtuins, Metabolism, and Cancer
    Bárbara Martínez-Pastor, Raúl Mostoslavsky · 2012 · Frontiers in Pharmacology
  53. Melatonin-mediated upregulation of Sirt3 attenuates sodium fluoride-induced hepatotoxicity by activating the MT1-PI3K/AKT-PGC-1α signaling pathway
    Chao Song, Jiamin Zhao, Beibei Fu, Dan Li, Tingchao Mao, Wei Peng, Haibo Wu, Yong Zhang · 2017 · Free Radical Biology and Medicine
  54. SIRT3 Overexpression Inhibits Growth of Kidney Tumor Cells and Enhances Mitochondrial Biogenesis
    Huan Liu, Siying Li, Xiaohui Liu, Yuling Chen, Haiteng Deng · 2018 · Journal of Proteome Research
  55. The alteration of hypoxia inducible factor-1 (HIF-1) and its target genes in mood disorder patients
    Tomohiko Shibata, Hirotaka Yamagata, Shusaku Uchida, Koji Otsuki, Teruyuki Hobara, Fumihiro Higuchi, Naoko Abe, Yoshifumi Watanabe · 2013 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  56. SIRT3 and SIRT4 are mitochondrial tumor suppressor proteins that connect mitochondrial metabolism and carcinogenesis
    Yueming Zhu, Yufan Yan, Daniel R. Principe, Xianghui Zou, Athanassios Vassilopoulos, David R. Gius · 2014 · Cancer & Metabolism
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  59. Sirtuins in Cancer: a Balancing Act between Genome Stability and Metabolism
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