SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production

Bell, E L, Emerling, B M, Ricoult, S J H, Guarente, L·2011·Oncogene

DOI 10.1038/onc.2011.37

Cited by (438)

Items 301–400 of 438

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Adjudin synergizes with paclitaxel and inhibits cell growth and metastasis by regulating the sirtuin 3–Forkhead box O3a axis in human small‐cell lung cancer
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Dzhuliia Sh. Dzhalilova, Olga V. Makarova · 2022 · Biochemistry (Moscow)
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Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice
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Khan Sadia, Mohammad Zahid Ashraf, Aastha Mishra · 2021 · Frontiers in Physiology
Sirtuins and Hypoxia in EMT Control
Michele Aventaggiato, Federica Barreca, Luigi Sansone, Laura Pellegrini, Matteo Antonio Russo, Marco Cordani, Marco Tafani · 2022 · Pharmaceuticals
Gene Expression Profiling Reveals Fundamental Sex-Specific Differences in SIRT3-Mediated Redox and Metabolic Signaling in Mouse Embryonic Fibroblasts
Robert Belužić, Ena Šimunić, Iva I. Podgorski, Marija Pinterić, Marijana Popović Hadžija, Tihomir Balog, Sandra Sobočanec · 2024 · International Journal of Molecular Sciences
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Forouzan Khodaei, Kiyanoosh Ahmadi, Hamze Kiyani, Mahmoud Hashemitabar, Mohsen Rezaei · 2018 · Europe PMC (PubMed Central)
The Prognostic and Clinicopathological Roles of Sirtuin-3 in Various Cancers
Fei‐Yuan Yu, Qian Xu, Dandan Wu, Andy T. Y. Lau, Yan‐Ming Xu · 2016 · PLoS ONE
Sirtuin 3-mediated delactylation of malic enzyme 2 disrupts redox balance and inhibits colorectal cancer growth
Chaoqun Li, Cun Ge, Qingwen Wang, Peng Teng, Heyuan Jia, Surui Yao, Zhaohui Huang · 2025 · Cellular Oncology
SIRT3 Regulates the ROS-FPR1/HIF-1α Axis under Hypoxic Conditions to Influence Lung Cancer Progression
Bo Huang, Jie Ding, Hongrong Guo, Hongjuan Wang, Jianqun Xu, Quan Zheng, LiJun Zhou · 2023 · Cell Biochemistry and Biophysics
SIRT2 inhibition activates hypoxia-inducible factor 1α signaling and mediates neuronal survival
Taku Kaitsuka, Masayuki Matsushita, Nobuko Matsushita · 2020 · Biochemical and Biophysical Research Communications
Uncovering SIRT3 and SHMT2-dependent pathways as novel targets for apigenin in modulating colorectal cancer: In vitro and in vivo studies
Nourhan M. Abdelmaksoud, Ahmed I. Abulsoud, Tamer M. Abdelghany, Shereen Saeid Elshaer, Sherine Maher Rizk, Mahmoud Ahmed Senousy, Nadine W. Maurice · 2024 · Experimental Cell Research
Regulation of Hypoxic Signaling and Oxidative Stress via the MicroRNA–SIRT2 Axis and Its Relationship with Aging-Related Diseases
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Molecular regulation of hypoxia through the lenses of noncoding RNAs and epitranscriptome
Safirul Islam, Chandrama Mukherjee · 2022 · Wiley Interdisciplinary Reviews - RNA
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I‐Chieh Chen, Hsin-Hsiu Huang, Pei‐Fen Chen, Hung‐Che Chiang · 2016 · Toxicological Sciences
A novel gene signature related to oxidative stress predicts the prognosis in clear cell renal cell carcinoma
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Acetylation and Phosphorylation in the Regulation of Hypoxia-Inducible Factor Activities: Additional Options to Modulate Adaptations to Changes in Oxygen Levels
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Luciferase-Based Reporter to Monitor the Transcriptional Activity of the SIRT3 Promoter
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Volney K. Friedrich, Meagan Rubel, Theodore G. Schurr · 2021 · American Journal of Human Biology
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Sirt3 deficiency promotes endothelial dysfunction and aggravates renal injury
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Luisa Carlotta Rossi, Cristiana Valle, Maria Teresa Carrı̀ · 2012 · International Journal of Cell Biology
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Hany N. Azzam, Marwa O. El-Derany, Sara A. Wahdan, Reham Mohamed Faheim, Gouda Kamel Helal, Ebtehal El‐Demerdash · 2022 · Scientific Reports
Myeloid Translocation Gene-16 Co-Repressor Promotes Degradation of Hypoxia-Inducible Factor 1
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Sirtuin1 attenuates acute liver failure by reducing reactive oxygen species via hypoxia inducible factor 1α
Pan Cao, Qian Chen, Chunxia Shi, Lu-Wen Wang, Zuojiong Gong · 2022 · World Journal of Gastroenterology
{2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic acid methyl ester (MIAM) inhibited human hepatocellular carcinoma growth through upregulation of Sirtuin-3 (SIRT3)
Ye Li, Wenjing Wang, Xiaoxue Xu, Shiyue Sun, Xian‐Jun Qu · 2014 · Biomedicine & Pharmacotherapy
Expression of SIRT3 in various glial cell types in the periventricular white matter in the neonatal rat brain after hypoxia
Xiuhua Li, Shun-Jin Liu, Xiaoyu Liu, Haiyu Zhao, Mao-Geng Yang, De-Xin Xu, Jing Guo, Jinghui Li, Juanjuan Li · 2018 · Tissue and Cell
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Swimming attenuates tumor growth in CT-26 tumor-bearing mice and suppresses angiogenesis by mediating the HIF-1α/VEGFA pathway
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{2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic Acid Methyl Ester Inhibited Hepatocellular Carcinoma Growth in Bel-7402 Cells and Its Resistant Variants by Activation of NOX4 and SIRT3
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Rashpal S. Dhillon, Jeffrey G. Richards · 2018 · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology
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한유선, 제갈명은, Young Jin Kim · 2019 · JoLS Journal of Life Sciences
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Igor B. Afanasʹev · 2012 · Current Signal Transduction Therapy
Sirtuins and Aging: is there a Role for Resveratrol?
Caterina Carollo, Alberto Firenze, Gregorio Caimi · 2016 · International Journal of Advanced Nutritional and Health Science
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Carles Cantó, Riekelt H. Houtkooper · 2016 · Springer eBooks
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Lorissa J. Smulan, Hardy Kornfeld, Amit Singhal · 2020 · Springer eBooks
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Surinder Kumar, William Giblin, David B. Lombard · 2021 · Elsevier eBooks
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Carcinogenic Compounds, 2-nitrofluorene and Clonidine Can Modulate the Level of Sirtuin mRNAs Expression in Human Adipose Tissue-derived Stem Cells
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