Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells

Liu, Z, Li, Q, Li, K, Chen, L, Li, W, Hou, M, Liu, T, Yang, J, Lindvall, C, Björkholm, M, Jia, J, Xu, D·2013·Oncogene
DOI 10.1038/onc.2012.441

Cited by (276)

Items 101–200 of 276

  1. Telomerase and hallmarks of cancer: An intricate interplay governing cancer cell evolution
    Naveen Kumar, Gautam Sethi · 2023 · Cancer Letters
  2. ASF1a inhibition induces p53-dependent growth arrest and senescence of cancer cells
    Yujiao Wu, Xidan Li, Jingya Yu, Magnus Björkholm, Dawei Xu · 2019 · Cell Death and Disease
  3. Ovarian Telomerase and Female Fertility
    Simon Toupance, Anne-Julie Fattet, Simon Nigel Thornton, Athanase Bénétos, Jean‐Louis Guéant, Isabelle Koscinski · 2021 · Biomedicines
  4. KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway
    Changlin Zhang, Chen Song, Tianze Liu, Ranran Tang, Miao Chen, Fan Gao, Binyi Xiao, Ge Qin, Fen Shi, Wenbin Li et al. · 2017 · Cell Death and Disease
  5. Enrichment of human osteosarcoma stem cells based on hTERT transcriptional activity
    Ling Yu, Shiqing Liu, Chun Zhang, Bo Zhang, Bruno M. Simões, Rachel Eyre, Yi Liang, Hui‐chao Yan, Zheng Wu, Weichun Guo et al. · 2013 · Oncotarget
  6. CDC5L Promotes hTERT Expression and Colorectal Tumor Growth
    Jia Li, Ningning Zhang, Rui Zhang, Longmei Sun, Wendan Yu, Wei Guo, Yingying Gao, Mei Li, Wei Liu, Pin Liang et al. · 2017 · Cellular Physiology and Biochemistry
  7. FN1 mRNA 3'-UTR supersedes traditional fibronectin 1 in facilitating the invasion and metastasis of gastric cancer through the FN1 3'-UTR-let-7i-5p-THBS1 axis
    Siwei Pan, Jiaming Zhu, Pengfei Liu, Qiaochu Wei, Siyu Zhang, Wen An, Yuxin Tong, Zhenguo Cheng, Funan Liu · 2023 · Theranostics
  8. Eribulin Mesylate Targets Human Telomerase Reverse Transcriptase in Ovarian Cancer Cells
    Satoko Yamaguchi, Yoshiko Maida, Mami Yasukawa, Tomoyasu Kato, Masayuki Yoshida, Kenkichi Masutomi · 2014 · PLoS ONE
  9. Fluorescence virus-guided capturing system of human colorectal circulating tumour cells for non-invasive companion diagnostics
    Kunitoshi Shigeyasu, Hiroshi Tazawa, Yuuri Hashimoto, Yoshiko Mori, Masahiko Nishizaki, Hiroyuki Kishimoto, Takeshi Nagasaka, Shinji Kuroda, Yasuo Urata, Ajay Goel et al. · 2014 · Gut
  10. Telomerase and CD4 T Cell Immunity in Cancer
    Magalie Dosset, Andrea Castro, Hannah K. Carter, Maurizio Zanetti · 2020 · Cancers
  11. Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of β-Catenin Target Genes
    Xiuming Liang, Xiaotian Yuan, Jingya Yu, Yujiao Wu, Kailin Li, Chao Sun, Shuyan Li, Li Shen, Feng Kong, Jihui Jia et al. · 2017 · EBioMedicine
  12. Shorter telomere length of white blood cells is associated with higher rates of aneuploidy among infertile women undergoing in vitro fertilization
    Brent M. Hanson, Xin Tao, Yiping Zhan, Julia G. Kim, Amber M. Klimczak, Nola S. Herlihy, Richard Thomas Scott, Emre U Seli · 2020 · Fertility and Sterility
  13. Telomerase Activation in Hematological Malignancies
    Joana Ropio, Jean‐Philippe Merlio, Paula Soares, Edith Chevret · 2016 · Genes
  14. Association of telomerase reverse transcriptase promoter mutations with clinicopathological features and prognosis of thyroid cancer: a meta-analysis
    Xingyun Su, Xiaoxia Jiang, Weibin Wang, Haiyong Wang, Xin Xu, Aihui Lin, Xiaodong Teng, Huiling Wu, Lisong Teng · 2016 · OncoTargets and Therapy
  15. Role of telomerase in the tumour microenvironment
    Ning Liu, Xuehua Guo, Junping Liu, Yu‐Sheng Cong · 2019 · Clinical and Experimental Pharmacology and Physiology
  16. hTERT promoter activity identifies osteosarcoma cells with increased EMT characteristics
    Ling Yu, Shiqing Liu, Weichun Guo, Chun Zhang, Bo Zhang, Hui‐chao Yan, Zheng Wu · 2013 · Oncology Letters
  17. Detection of circulating tumor cells in cervical cancer using a conditionally replicative adenovirus targeting telomerase‐positive cells
    Masahiro Takakura, Takeo MATSUMOTΟ, Mitsuhiro Nakamura, Yasunari Mizumoto, Subaru Myojo, Rena Yamazaki, Jyunpei Iwadare, Yukiko Bono, Orisaka Shunsuke, Takeshi Obata et al. · 2017 · Cancer Science
  18. TERT Promoter Mutations and Their Impact on Gene Expression Profile in Papillary Thyroid Carcinoma
    Dagmara Rusinek, Aleksandra Pfeifer, Marta Cieślicka, Małgorzata Kowalska, Agnieszka Pawlaczek, Jolanta Krajewska, Sylwia Szpak‐Ulczok, Tomasz Tyszkiewicz, Monika Halczok, Agnieszka Czarniecka et al. · 2020 · Cancers
  19. BMI-1 activation is crucial in hTERT-induced epithelial–mesenchymal transition of oral epithelial cells
    Bin Qiao, Zhifeng Chen, Fengchun Hu, Qian Tao, Alfred King-yin Lam · 2013 · Experimental and Molecular Pathology
  20. Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells
    Xinyu Ci, Bingnan Li, Xueping Ma, Feng Kong, Chengyun Zheng, Magnus Björkholm, Jihui Jia, Dawei Xu · 2015 · Oncotarget
  21. TERT rs2736100 genotypes are associated with differential risk of myeloproliferative neoplasms in Swedish and Chinese male patient populations
    Jenny Dahlström, Tiantian Liu, Xiaotian Yuan, Leonie Saft, Mehran Ghaderi, Ya Bin Wei, Catharina Lavebratt, Ping Li, Chengyun Zheng, Magnus Björkholm et al. · 2016 · Annals of Hematology
  22. Salinomycin Abolished STAT3 and STAT1 Interactions and Reduced Telomerase Activity in Colorectal Cancer Cells
    SEYUNG S. CHUNG, Debbie Adekoya, IKECHUKWU ENENMOH, Orette Clarke, Piwen Wang, MARIANNA SARKYSSIAN, Yong Wu, Jaydutt V. Vadgama · 2017 · Anticancer Research
  23. Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial
    Espen B. Ellingsen, Steven J O'Day, Artur Mezheyeuski, Agnieszka Gromadka, Trevor Clancy, Timothy S. Kristedja, Mohammed M. Milhem, Yousef Zakharia · 2023 · Clinical Cancer Research
  24. Telomerase reverse transcriptase potentially promotes the progression of oral squamous cell carcinoma through induction of epithelial-mesenchymal transition
    Tengda Zhao, FENGCHUN HU, Bin Qiao, Zhifeng Chen, Qian Tao · 2015 · International Journal of Oncology
  25. Means to the ends: The role of telomeres and telomere processing machinery in metastasis
    Nathaniel J Robinson, William P. Schiemann · 2016 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  26. Efficacy of GV1001 with gemcitabine/capecitabine in previously untreated patients with advanced pancreatic ductal adenocarcinoma having high serum eotaxin levels (KG4/2015): an open-label, randomised, Phase 3 trial
    Jung Hyun Jo, Yong‐Tae Kim, Ho Soon Choi, Ho Gak Kim, Hong Sik Lee, Young Woo Choi, Dong Uk Kim, Kwang Hyuck Lee, Eui Joo Kim, Joung‐Ho Han et al. · 2023 · British Journal of Cancer
  27. Telomerase and Telomeres Biology in Thyroid Cancer
    Benedetta Donati, Alessia Ciarrocchi · 2019 · International Journal of Molecular Sciences
  28. Telomerase reverse transcriptase inhibition stimulates cyclooxygenase 2 expression in cancer cells and synergizes with celecoxib to exert anti-cancer effects
    T Liu, Xiaohong Liang, Bingnan Li, Magnus Björkholm, Jihui Jia, Dawei Xu · 2013 · British Journal of Cancer
  29. RIF1 promotes human epithelial ovarian cancer growth and progression via activating human telomerase reverse transcriptase expression
    Yongbin Liu, Ying Mei, Jing Long, Yu Zhang, Dongli Hu, Hong‐Hao Zhou · 2018 · Journal of Experimental & Clinical Cancer Research
  30. Telomeres, telomerase, and cancer: mechanisms, biomarkers, and therapeutics
    Songting Shou, Ayidana Maolan, Di Zhang, Xiaochen Jiang, Fudong Liu, Yi Li, Xiyuan Zhang, En Geer, Zhenqing Pu, Baojin Hua et al. · 2025 · Experimental Hematology and Oncology
  31. New surprises from an old favourite: The emergence of telomerase as a key player in the regulation of cancer stemness
    Kerem Teralı, Açelya Yılmazer · 2015 · Biochimie
  32. Pin2 telomeric repeat factor 1-interacting telomerase inhibitor 1 (PinX1) inhibits nasopharyngeal cancer cell stemness: implication for cancer progression and therapeutic targeting
    Chaosheng Yu, Fang Chen, Xiaoqi Wang, Zhimou Cai, Mengxue Yang, Qingwen Zhong, Jialian Feng, Junzheng Li, Congxiang Shen, Zhong Wen · 2020 · Journal of Experimental & Clinical Cancer Research
  33. Role of Telomeres Shortening in Atherogenesis: An Overview
    Yegor E. Yegorov, Anastasia Vladimirovna Poznyak, Nikita Gennadievich Nikiforov, Antonina Vladimirovna Starodubova, Alexander Nikolaevich Orekhov · 2021 · Cells
  34. Many Functions of Telomerase Components: Certainties, Doubts, and Inconsistencies
    Ion Udroiu, Jessica Marinaccio, Antonella Sgura · 2022 · International Journal of Molecular Sciences
  35. PinX1: structure, regulation and its functions in cancer
    Hailong Li, Jun Ho Song, Hongmei Yong, Pingfu Hou, Yansu Chen, Wenbo Song, Jin Bai, Junnian Zheng · 2016 · Oncotarget
  36. NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer
    Feng Xu, Xiangdong Xu, Xiangsheng Xiao, Kun Zou, Wendan Yu, Jiali Wu, Ranran Tang, Yue Gao, Jiaojiao Hao, Xinrui Zhao et al. · 2017 · Cell Death and Disease
  37. TERT Promoter Hypermethylation in Gastrointestinal Cancer: A Potential Stool Biomarker
    Li Liu, Cheng Liu, Omid Fotouhi, Yidong Fan, Kun Wang, Chuanyou Xia, Benkang Shi, Guangyong Zhang, Kexin Wang, Feng Kong et al. · 2017 · The Oncologist
  38. Ablation of human telomerase reverse transcriptase (hTERT) induces cellular senescence in gastric cancer through a galectin-3 dependent mechanism
    Sun-Hyuk La, Seok-Jun Kim, Hyeok-Gu Kang, Han‐Woong Lee, Kyung‐Hee Chun · 2016 · Oncotarget
  39. NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma
    Vilde Drageset Haakensen, Anna K. Nowak, Espen B. Ellingsen, Saima Jamil Farooqi, Maria Moksnes Bjaanæs, Henrik Horndalsveen, Tine McCulloch, Oscar Grundberg, S. Cedrés, Åslaug Helland · 2021 · Journal of Translational Medicine
  40. A Critical YAP in Malignancy of HCC Is Regulated by Evodiamine
    Un-Jung Yun, Su-Jin Bae, Yu-Rim Song, Young Woo Kim · 2022 · International Journal of Molecular Sciences
  41. Resveratrol attenuates norepinephrine-induced ovarian cancer invasiveness through downregulating hTERT expression
    Seung Hwa Kim, Kyung Hwa Cho, Yu Na Kim, Bo Young Jeong, Chang Gyo Park, Gang Min Hur, Hoi Young Lee · 2015 · Archives of Pharmacal Research
  42. Helicobacter pylori ‐activated gastric fibroblasts induce epithelial‐mesenchymal transition of gastric epithelial cells in vitro in a TGF‐β‐dependent manner
    Gracjana Krzysiek-Mączka, Tomasz Wróbel, Aneta Targosz, Urszula Szczyrk, Małgorzata Strzałka, Agata Ptak‐Belowska, Jarosław Czyż, Tomasz Brzozowski · 2019 · Helicobacter
  43. RNA expression profiling reveals PRAME, a potential immunotherapy target, is frequently expressed in solitary fibrous tumors
    Wei-Lien Wang, Nalan Gökgöz, Bana Samman, Irene Louise Andrulis, Jay Steven Wunder, Elizabeth G. Demicco · 2020 · Modern Pathology
  44. Epithelial to mesenchymal transition (EMT) in metaplastic breast cancer and phyllodes breast tumors
    Ιωάννα Ακρίδα, Francesk Mulita, Kerasia‐Maria Plachouri, Nikolaos Benetatos, Ioannis C. Maroulis, Helen H. Papadaki · 2023 · Medical Oncology
  45. TERT , HRAS , and EIF1AX Mutations in a Patient with Follicular Adenoma
    Michael C. Topf, Zixuan Wang, Madalina Tuluc, Edmund A. Pribitkin · 2018 · Thyroid
  46. Implications of telomerase reverse transcriptase in tumor metastasis
    Yongkang Zou, Yu‐Sheng Cong, Junzhi Zhou · 2020 · BMB Reports
  47. MYC-dependent downregulation of telomerase by FLT3 inhibitors is required for their therapeutic efficacy on acute myeloid leukemia
    Xiaolu Zhang, Bingnan Li, Jingya Yu, Jenny Dahlström, Anh Nhi Tran, Magnus Björkhom, Dawei Xu · 2017 · Annals of Hematology
  48. Application of a telomerase-based circulating tumor cell (CTC) assay in bladder cancer patients receiving postoperative radiation therapy
    Melody Ju, Gary D. Kao, David Steinmetz, Sanjay Chandrasekaran, Stephen J. O’Keefe, Thomas J. Guzzo, John Paul Christodouleas, Stephen M. Hahn, Jay F. Dorsey · 2014 · Cancer Biology & Therapy
  49. Telomeres and Telomerase in Cutaneous Squamous Cell Carcinoma
    Alessandra Ventura, Cristina Pellegrini, Ludovica Cardelli, Tea Rocco, Valeria Ciciarelli, Ketty Peris, Maria Concetta Fargnoli · 2019 · International Journal of Molecular Sciences
  50. Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination
    Espen B. Ellingsen, Gergana Bounova, Iliana Kyriaki Kerzeli, Irantzu Anzar, Donjetë Simnica, Elin Aamdal, Tormod Kyrre Guren, Trevor Clancy, Artur Mezheyeuski, Else Marit Inderberg et al. · 2022 · Journal of Translational Medicine
  51. TERT promoter mutations and methylation for telomerase activation in urothelial carcinomas: New mechanistic insights and clinical significance
    Tiantian Liu, Shihong Li, Chuanyou Xia, Dawei Xu · 2023 · Frontiers in Immunology
  52. shRNA-mediated silencing of hTERT suppresses proliferation and promotes apoptosis in osteosarcoma cells
    Ping Chen, W-L Gu, M-Z Gong, J Wang, D-Q Li · 2017 · Cancer Gene Therapy
  53. The role of telomerase and viruses interaction in cancer development, and telomerase-dependent therapeutic approaches
    Ali Salimi Jeda, Fariba Badrzadeh, Maryam Esghaei, Asghar Abdoli · 2021 · Cancer Treatment and Research Communications
  54. Therapeutic potential of cancer stem cells
    Chunguang Yang, Kunlin Jin, Yangping Tong, William Chi Shing Cho · 2015 · Medical Oncology
  55. Differential telomerase expression in idiopathic pulmonary fibrosis and non-small cell lung cancer
    Katerina M. Antoniou, Katerina D Samara, Ismini Lasithiotaki, George A. Margaritopoulos, Giannoula Soufla, Irini Lambiri, Ioannis Giannarakis, Ioannis Drositis, Demetrios A. Spandidos, Nikolaos M. Siafakas · 2013 · Oncology Reports
  56. Ultrasonographic prediction of highly aggressive telomerase reverse transcriptase (TERT) promoter-mutated papillary thyroid cancer
    Tae Hyuk Kim, Chang‐Seok Ki, Soo Yeon Hahn, Young Lyun Oh, Hye Won Jang, Sun Wook Kim, Jae Hoon Chung, Jung Hee Shin · 2017 · Endocrine
  57. Human telomerase reverse transcriptase is a novel target of Hippo‐YAP pathway
    Qian Zhang, Ning Liu, Junjie Bai, Qi Zhou, Jian Mao, Lu Xu, Jiang Liu, Haibin Wei, Chengcheng Ren, Xiaoying Wu et al. · 2020 · The FASEB Journal
  58. SPT6 recruits SND1 to co‐activate human telomerase reverse transcriptase to promote colon cancer progression
    Chaoliang Diao, Ping Guo, Wenjing Yang, Yao Sun, Yina Liao, Yue Yan, Anshi Zhao, Xin Cai, Jiaojiao Hao, Sheng Chuan Hu et al. · 2020 · Molecular Oncology
  59. Positive association of long telomeres with the invasive capacity of hepatocellular carcinoma cells
    Eunkyong Ko, Guhung Jung · 2014 · Biochemical and Biophysical Research Communications
  60. hTERT promotes tumor progression by enhancing TSPAN13 expression in osteosarcoma cells
    Rishi Kumar Jaiswal, Pramod Kumar, Manoj Kumar, Pramod Kumar Yadava · 2018 · Molecular Carcinogenesis
  61. Proton pump inhibitor pantoprazole inhibits gastric cancer metastasis via suppression of telomerase reverse transcriptase gene expression
    Bin Zhang, Tingsheng Ling, Panduo Zhaxi, Yu Qing Cao, Liping Qian, Dian Zhao, Wei Kang, Weijie Zhang, Lei Wang, Guifang Xu et al. · 2019 · Cancer Letters
  62. Mechanisms of TERT Reactivation and Its Interaction with BRAFV600E
    Young Shin Song, Young Joo Park · 2020 · Endocrinology and Metabolism
  63. TGF-β1 pathway affects the protein expression of many signaling pathways, markers of liver cancer stem cells, cytokeratins, and TERT in liver cancer HepG2 cells
    Xinhong Wang, Ming-Na Liu, Xun Sun, Chun-Huan Xu, Jing Liu, Jing Chen, Ruiling Xu, Baoxin Li · 2015 · Tumor Biology
  64. Correction to: MYC-dependent downregulation of telomerase by FLT3 inhibitors is required for their therapeutic efficacy on acute myeloid leukemia
    Xiaolu Zhang, Bingnan Li, Jingya Yu, Jenny Dahlström, Anh Nhi Tran, Magnus Björkholm, Dawei Xu · 2018 · Annals of Hematology
  65. A positive feedback loop between Wnt/β‐catenin signaling and hTERT regulates the cancer stem cell‐like traits in radioresistant nasopharyngeal carcinoma cells
    Kai-Hua Chen, Li Chen, Ling Li, Song Qu, Binbin Yu, Yongchu Sun, Fangzhu Wan, Xishan Chen, Renba Liang, Xiaodong Zhu · 2020 · Journal of Cellular Biochemistry
  66. Human Telomerase Reverse Transcriptase Promotes the Epithelial to Mesenchymal Transition in Lung Cancer Cells by Enhancing c-MET Upregulation
    Ram Raj Prasad, Deepak Kumar Mishra, Manoj Kumar, Pramod Kumar Yadava · 2021 · Heliyon
  67. Telomerase activity in the occurrence and progression of oral squamous cell carcinoma
    Yuji Miyazaki, Noriaki Yoshida, Tadashige Nozaki, Harumi Inoue, Kentaro Kikuchi, Kaoru Kusama · 2015 · Journal of Oral Science
  68. Astragaloside IV suppresses transforming growth factor-β1-induced epithelial–mesenchymal transition through inhibition of Wnt/β-catenin pathway in glioma U251 cells
    Jinming Han, Xiaohan Shen, Yong Zhang, Suying Wang, Lei-Jie Zhou · 2020 · Bioscience Biotechnology and Biochemistry
  69. The telomerase gene polymorphisms, but not telomere length, increase susceptibility to primary glomerulonephritis/end stage renal diseases in females
    Qing Sun, Junli Liu, Guanghui Cheng, Mingkai Dai, Jiaxi Liu, Zhenqiang Qi, Jingjie Zhao, Wei Li, Feng Kong, Gang Liu et al. · 2020 · Journal of Translational Medicine
  70. Advancements in the Diagnosis, Treatment, and Risk Stratification of Non-Muscle Invasive Bladder Cancer
    Shayan Smani, Julien DuBois, Kai Sun Zhao, Ryan Sutherland, Syed N. Rahman, Peter A. Humphrey, DAVID G. HESSE, Wei Shen Tan, Darryl T. Martin, Soum D. Lokeshwar et al. · 2025 · Current Oncology Reports
  71. TERT promoter C228T mutation in neural progenitors confers growth advantage following telomere shortening in vivo
    Shunichiro Miki, Tomoyuki Koga, Andrew McKinney, Alison D. Parisian, Takahiro Tadokoro, Raghavendra Vadla, Martin Maršala, Robert F. Hevner, J Costello, Frank B. Furnari · 2022 · Neuro-Oncology
  72. The TERT locus genotypes of rs2736100-CC/CA and rs2736098-AA predict shorter survival in renal cell carcinoma
    Runzhuo Ma, Cheng Liu, Min Lu, Xiaotian Yuan, Guanghui Cheng, Feng Kong, Jian Guo Lu, Klas Strååt, Magnus Björkholm, Lulin Ma et al. · 2019 · Urologic Oncology Seminars and Original Investigations
  73. Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT
    Qian Yang, Wenhua Fan, Zongheng Zheng, Shiyong Lin, Congcong Liu, Ruozhu Wang, Wenyang Li, Yan Zuo, Yao Sun, Sheng Chuan Hu et al. · 2019 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  74. Telomerase reverse transcriptase promoter mutations in thyroid carcinomas: implications in precision oncology—a narrative review
    Xiaotian Yuan, Tiantian Liu, Dawei Xu · 2020 · Annals of Translational Medicine
  75. Genomic, epigenomic, and transcriptomic signatures for telomerase complex components: a pan‐cancer analysis
    Jing Wang, Mingkai Dai, Xiangling Xing, Xing Wang, Xin Qin, Tao Huang, Zhiqing Fang, Yidong Fan, Dawei Xu · 2022 · Molecular Oncology
  76. The association between the TERT rs2736100 AC genotype and reduced risk of upper tract urothelial carcinomas in a Han Chinese population
    Xiaotian Yuan, Yan Meng, Ping Li, Nan Ge, Feng Kong, Yang Liu, Magnus Björkholm, Shengtian Zhao, Dawei Xu · 2016 · Oncotarget
  77. Correlation of TERT and Stem Cell Markers in the Context of Human Breast Cancer
    Umar Wazir, MONA M.A.W. ORAKZAI, Tracey Amanda Martin, Wen G. Jiang, Kefah Mokbel · 2019 · Cancer Genomics & Proteomics
  78. Histone demethylase PHF8 promotes progression and metastasis of gastric cancer.
    Shuyan Li, Ao Sun, Xiuming Liang, Lin Ma, Li Shen, Tongyu Li, Lixin Zheng, Wenjing Shang, Wei Zhao, Jihui Jia · 2017 · PubMed Central
  79. Regulatory region mutations of TERT , PLEKHS1 and GPR126 genes as urinary biomarkers in upper tract urothelial carcinomas
    Xiangling Xing, Xiaotian Yuan, Tiantian Liu, Mingkai Dai, Yidong Fan, Cheng Liu, Klas Strååt, Magnus Björkholm, Dawei Xu · 2021 · Journal of Cancer
  80. AKT plays a crucial role in gastric cancer
    Takamitsu Sasaki, Yuichi Yamashita, Hiroki Kuniyasu · 2015 · Oncology Letters
  81. A telomerase with novel non-canonical roles: TERT controls cellular aggregation and tissue size in Dictyostelium
    Nasna Nassir, Geoffrey J. Hyde, Ramamurthy Baskar · 2019 · PLoS Genetics
  82. The non-reverse transcriptase activity of the human telomerase reverse transcriptase promotes tumor progression (Review)
    Yong Qin, Hong Yan Guo, Bo Tang, Shiming Yang · 2014 · International Journal of Oncology
  83. Telomerase inhibition regulates EMT mechanism in breast cancer stem cells
    Alican Kuşoğlu, Bakiye Göker Bağca, Neslihan Pınar Özateş, Cumhur Gündüz, Çığır Biray Avcı · 2020 · Gene
  84. Telomere and Telomerase in Carcinogenesis: Their Role as Prognostic Biomarkers
    Silvia Giunco, Enrica Rampazzo, Andrea Celeghin, Maria Raffaella Petrara, Anita De Rossi · 2015 · Current Pathobiology Reports
  85. Telomerase reverse transcriptase interference synergistically promotes tumor necrosis factor‑related apoptosis‑inducing ligand‑induced oral squamous cell carcinoma apoptosis and suppresses proliferation in�vitro and in�vivo
    Xin Zhao, Cuicui Zhang, Zhiliang Le, Suyun Zeng, Chaobin Pan, Jianjie Shi, Jianguang Wang, Xiaopeng Zhao · 2018 · International Journal of Molecular Medicine
  86. A global and physical mechanism of gastric cancer formation and progression
    Chong Yu, Hong Xu, Jin Wang · 2021 · Journal of Theoretical Biology
  87. TERT Promoter Mutations Increase Sense and Antisense Transcription from the TERT Promoter
    François Hafezi, Lisa Jaxel, Morgane Lemaire, Jonathan D. Turner, Danielle Perez-Bercoff · 2021 · Biomedicines
  88. Telomere - A Complex End of a Chromosome
    Marcelo Luis Larramendy · 2016 · InTech eBooks
  89. Synergistic effects of telomerase reverse transcriptase and regulator of telomere elongation helicase 1 on aggressiveness and outcomes in adrenocortical carcinoma
    Huiyang Yuan, Yujiao Wu, Jing Wang, Xin Qin, Yong-sheng Huang, Lei Yan, Yidong Fana, Jan Zedenius, C. Christofer Juhlin, Catharina Larsson et al. · 2022 · Biomedicine & Pharmacotherapy
  90. IDH mutation and cancer stem cell
    Yang Zhang, Yang Liu, Fengchao Lang, Chunzhang Yang · 2022 · Essays in Biochemistry
  91. The dynamics of telomere length in primary and metastatic colorectal cancer lesions
    Kroupa, Michal, Kubecek, Ondrej, Tomasova, Kristyna, Hanak, Petr, Krupova, Marketa, Cervena, Klara, Siskova, Anna, Rosendorf, Jachym, Hosek, Petr, Vodickova, Ludmila et al. · 2023 · Scientific Reports
  92. The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study
    Yuanqing Cai, Huijun Sun, Xingyu Song, Jianyu Zhao, Dong Xu, Mozhen Liu · 2023 · Aging
  93. Noncanonical functions of telomerase and telomeres in viruses‐associated cancer
    Sara Rasouli, Aleksandra Dakic, Qi‐En Wang, Darrion Mitchell, Dukagjin M. Blakaj, Nagireddy Putluri, Jenny Li, Xuefeng Liu · 2024 · Journal of Medical Virology
  94. Recent Progress and Potential of G4 Ligands in Cancer Immunotherapy
    Jiahui Lin, Zhu Gong, Yen‐Shen Lu, Jiongheng Cai, Junjie Zhang, Jia‐Heng Tan, Zhi‐Shu Huang, Shuobin Chen · 2025 · Molecules
  95. Human chromosome 3p21.3 carries TERT transcriptional regulators in pancreatic cancer
    Takuki Yagyu, Takahito Ohira, Ryutaro Shimizu, Masaki Morimoto, Yuki Murakami, Takehiko Hanaki, Kyoichi Kihara, Tomoyuki Matsunaga, Manabu Yamamoto, Naruo Tokuyasu et al. · 2021 · Scientific Reports
  96. hTERT gene polymorphism correlates with the risk and the prognosis of thyroid cancer
    Long Gong, Ying Xu, Ya-Qin Hu, Qiuju Ding, Chun-Hua Yi, Wei Huang, Ming Zhou · 2016 · Cancer Biomarkers
  97. The association of telomere maintenance and TERT expression with susceptibility to human papillomavirus infection in cervical epithelium
    Lina Wang, Li Wang, Guanghui Cheng, Mingkai Dai, Yunhai Yu, Guoxin Teng, Jingjie Zhao, Dawei Xu · 2022 · Cellular and Molecular Life Sciences
  98. Association Between the Telomerase rs2736098_TT Genotype and a Lower Risk of Chronic Hepatitis B and Cirrhosis in Chinese Males
    Guanghui Cheng, Xiaotian Yuan, Fang Wang, Qing Sun, Qian Xin, Kailin Li, Chao Sun, Zhao‐Min Lin, Yun Luan, Yiteng Xu et al. · 2017 · Clinical and Translational Gastroenterology
  99. Inhibiting the growth of melanoma cells via hTERT gene editing using CRISPR-dCas9-dnmt3a system
    Farbod Taghavi Rad, Bahar Naghavi Gargari, Saied Ghorbian, Zeinab Shirvani-Farsani, Rasoul Sharifi · 2022 · Gene
  100. Fumonisin B1 Inhibits Endoplasmic Reticulum Stress Associated-apoptosis After FoscanPDT Combined with C6-Pyridinium Ceramide or Fenretinide
    Nithin B. Boppana, Jacqueline M. Kraveka, Mehrdad Rahmaniyan, L I Li, Alicja E. Bielawska, Jacek Bielawski, Jason S. Pierce, Jeremy S. DeLor, Kezhong Zhang, Mladen Korbelik et al. · 2017 · Anticancer Research