Persistent depressive symptoms, HPA-axis hyperactivity, and inflammation: the role of cognitive-affective and somatic symptoms

Diagnostic and Statistical Manual of Mental Disorders

American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369

The CES-D Scale: A Self-Report Depression Scale for Research in the General Population

Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267

Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies

Lang, U. E., & Borgwardt, S. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350094 · Cited by 8,526

From inflammation to sickness and depression: when the immune system subjugates the brain

Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2297 · Cited by 7,395

Physiology and neurobiology of stress and adaptation: central role of the brain

McEwen, B. S. (2007) · Physiological Reviews · doi:10.1152/physrev.00041.2006 · Cited by 5,429

Screening for Depression in Well Older Adults: Evaluation of a Short Form of the CES-D

Andresen, E. M., Malmgren, J. A., Carter, W. B., & Patrick, D. L. (1994) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(18)30622-6 · Cited by 5,403

A Meta-Analysis of Cytokines in Major Depression

Dowlati, Y., Herrmann, N., Swardfager, W., Liu, H., Sham, L., Reim, E. K., & Lanctôt, K. L. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.033 · Cited by 4,729

Screening for depression in well older adults: evaluation of a short form of the CES-D (Center for Epidemiologic Studies Depression Scale).

Andresen, E. M., Malmgren, J. A., Carter, W. B., & Patrick, D. L. (1994) · PubMed · Cited by 4,426

Depression

Malhi, G. S., & Mann, J. J. (2018) · The Lancet · doi:10.1016/s0140-6736(18)31948-2 · Cited by 4,099

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

Miller, A. H., Maletic, V., & Raison, C. L. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.11.029 · Cited by 3,848

Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management

Berk, M., Köhler‐Forsberg, O., Turner, M., Penninx, B. W. J. H., Wrobel, A., Firth, J., Loughman, A., Reavley, N. J., McGrath, J. J., Momen, N. C., et al. (2023) · World Psychiatry · doi:10.1002/wps.21110 · Cited by 336

Psychological comorbidity in gastrointestinal diseases: Update on the brain-gut-microbiome axis

Person, H., & Keefer, L. (2021) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.110209 · Cited by 158

The social ecology of childhood and early life adversity

Lopez, M., Ruiz, M. O., Rovnaghi, C. R., Tam, G. K.-Y., Hiscox, J., Gotlib, I. H., Barr, D. A., Carrión, V. G., & Anand, K. J. S. (2021) · Pediatric Research · doi:10.1038/s41390-020-01264-x · Cited by 200

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Johnson, D., Thurairajasingam, S., Letchumanan, V., Chan, K., & Lee, L. (2021) · Nutrients · doi:10.3390/nu13051728 · Cited by 117

Biomarkers of post-covid depression

Lorkiewicz, P., & Waszkiewicz, N. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10184142 · Cited by 102

Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder

Green, C., Shen, X., Stevenson, A. J., Conole, E. L. S., Harris, M. A., Barbu, M. C., Hawkins, E. L., Adams, M. J., Hillary, R. F., Lawrie, S. M., et al. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.11.024 · Cited by 103

The long-term association of adverse childhood experiences with C-reactive protein and hair cortisol: Cumulative risk versus dimensions of adversity

Iob, E., Lacey, R. E., & Steptoe, A. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.12.019 · Cited by 95

Is depression the missing link between inflammatory mediators and cancer?

Polityńska, B., Pokorska, O., Wojtukiewicz, A. M., Sawicka, M., Mysliwiec, M., Honn, K. V., Tucker, S. C., & Wojtukiewicz, M. Z. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108293 · Cited by 83

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Iob, E., Lacey, R. E., & Steptoe, A. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.07.045 · Cited by 70

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Chung, D. D., Pinson, M. R., Bhenderu, L. S. S., Lai, M. S., Patel, R. A., & Miranda, R. C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168785 · Cited by 81

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Liu, Y., Duan, L., Shen, Q., Ma, Y., Chen, Y., Xu, L., Wu, Y., & Zhang, T. (2024) · Scientific Reports · doi:10.1038/s41598-024-60326-w · Cited by 68

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Johnston, J. N., Kadriu, B., Allen, J., Gilbert, J. R., Henter, I. D., & Zarate, C. A. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109422 · Cited by 73

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Lee, M. T., Peng, W., Kan, H., Wu, C., Wang, D., & Ho, Y. (2022) · Biomedicines · doi:10.3390/biomedicines10051005 · Cited by 67

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Johnston, J. N., Greenwald, M. S., Henter, I. D., Kraus, C., Mkrtchian, A., Clark, N. G., Park, L. T., Gold, P. W., Zarate, C. A., & Kadriu, B. (2023) · Drug Discovery Today · doi:10.1016/j.drudis.2023.103518 · Cited by 68

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Javaheripour, N., Čolić, L., Opel, N., Li, M., Balajoo, S. M., Chand, T., van der Meer, J. N., Krylova, M., Izyurov, I., Meller, T., et al. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02540-0 · Cited by 67

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Manosso, L. M., Camargo, A., Dafré, A. L., & Rodrigues, A. L. S. (2020) · Nutritional Neuroscience · doi:10.1080/1028415x.2020.1853417 · Cited by 64

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Johnson, D., Letchumanan, V., Thum, C. C., Thurairajasingam, S., & Lee, L. (2023) · Nutrients · doi:10.3390/nu15061382 · Cited by 72

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Richardson, B., MacPherson, A., & Bambico, F. R. (2022) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2022.100554 · Cited by 57

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Iob, E., Baldwin, J. R., Plomin, R. J., & Steptoe, A. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01538-w · Cited by 53

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Brás, J. P., de Suduiraut, I. G., Zanoletti, O., Monari, S., Meijer, M., Grosse, J., Barbosa, M. A., Santos, S. G., Sandi, C., & Almeida, M. I. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.10.018 · Cited by 58

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Ortega, V. A., Mercer, E. M., Giesbrecht, G. F., & Arrieta, M. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.634539 · Cited by 55

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Guo, H., Zheng, L., Xu, H., Pang, Q., Ren, Z., Gao, Y. Z., & Wang, T. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/8111022 · Cited by 56

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Jembrek, M. J., Oršolić, N., Karlović, D., & Peitl, V. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24086888 · Cited by 58

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Majumdar, S., Gupta, S., Prajapati, S. K., & Krishnamurthy, S. (2021) · Neurochemistry International · doi:10.1016/j.neuint.2021.105013 · Cited by 54

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Poppa, T., Benschop, L., Horczak, P., Vanderhasselt, M., Carrette, E., Bechara, A., Baeken, C., & Vonck, K. E. J. (2021) · Brain stimulation · doi:10.1016/j.brs.2021.12.004 · Cited by 53

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Hwang, D.-J., Koo, J., Kim, T.-K., Jang, Y., Hyun, A.-H., Yook, J.-S., Yoon, C.-S., & Cho, J. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1259711 · Cited by 49

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Pohl, T. T., Jung, O., Benedetto, B. D., Young, L. J., & Bosch, O. J. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.05.026 · Cited by 48

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Petruso, F., Giff, A., Milano, B. A., Rossi, M. M. D., & Saccaro, L. F. (2023) · Neuronal Signaling · doi:10.1042/ns20220077 · Cited by 53

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Preez, A. D., Eum, J., Eiben, I., Eiben, P., Zunszain, P. A., Pariante, C. M., Thuret, S., & Fernandes, C. (2020) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2020.100896 · Cited by 49

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Chu, K., Cadar, D., Iob, E., & Frank, P. (2022) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2022.11.016 · Cited by 48

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Clerici, L., Bottari, D., & Bottari, B. (2025) · Current Nutrition Reports · doi:10.1007/s13668-025-00619-2 · Cited by 54

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Schlechter, P., Ford, T. J., & Neufeld, S. (2022) · Assessment · doi:10.1177/10731911221138930 · Cited by 43

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Wang, L., Hu, Y., Jiang, N., & Yetisen, A. K. (2024) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2024.116242 · Cited by 50

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Cocean, A.-M., & Vodnar, D. C. (2024) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2024.111073 · Cited by 52

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Ju, Y., Wang, M., Lu, X., Sun, J., Dong, Q., Zhang, L., Liu, B., Liu, J., Yan, D., Guo, H., et al. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.07.023 · Cited by 45

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Tang, M., Shi, Y., Jiang, X., Xu, H., Ma, Y., & Zhao, B. (2021) · Journal of Materials Chemistry C · doi:10.1039/d1tc01342d · Cited by 42

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Lin, L., Herselman, M. F., Zhou, X., & Bobrovskaya, L. (2022) · Physiology & Behavior · doi:10.1016/j.physbeh.2022.113721 · Cited by 41

Chaperone Sigma1R and Antidepressant Effect

Воронин, М. В., Vakhitova, Y. V., & Середенин, С. Б. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21197088 · Cited by 41

miR-218 in Adolescence Predicts and Mediates Vulnerability to Stress

Torres‐Berrío, A., Morgunova, A., Giroux, M., Cuesta, S., Nestler, E. J., & Flores, C. (2020) · Biological Psychiatry · doi:10.1016/j.biopsych.2020.10.015 · Cited by 40

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Teckentrup, V., & Kroemer, N. B. (2023) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2023.11.001 · Cited by 42

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Faraji, J., & Metz, G. A. S. (2021) · Aging and Disease · doi:10.14336/ad.2021.0319 · Cited by 44

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Thomas, K. R., Watt, J., Wu, C. M. J., Akinrinoye, A., Amjad, S., Colvin, L., Cowe, R., Duncan, S. H., Russell, W. R., & Forget, P. (2022) · Biomedicines · doi:10.3390/biomedicines10081815 · Cited by 38

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Stanton, L. M., Price, A. J., & Manning, E. E. (2023) · Journal of Neuroendocrinology · doi:10.1111/jne.13268 · Cited by 40

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Kerber, A., Ehrenthal, J. C., Zimmermann, J., Remmers, C., Nolte, T., Wendt, L. P., Heim, P., Müller, S., Beintner, I., & Knaevelsrud, C. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03046-z · Cited by 37

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Ferstl, M., Kühnel, A., Klaus, J., Lin, W. M., & Kroemer, N. B. (2024) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2024.152488 · Cited by 33

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Yu, X., Yao, H., Zhang, X., Liu, L., Liu, S., & Dong, Y. (2022) · BMC Psychiatry · doi:10.1186/s12888-022-04233-2 · Cited by 33

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McLaughlin, A. P., Nikkheslat, N., Hastings, C. N. M., Nettis, M. A., Kose, M., Worrell, C., Zajkowska, Z., Mariani, N., Enache, D., Lombardo, G., et al. (2021) · Psychological Medicine · doi:10.1017/s0033291721000088 · Cited by 32

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Schnellbächer, G. J., Rajkumar, R., Veselinović, T., Ramkiran, S., Hagen, J., Shah, N. J., & Neuner, I. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103249 · Cited by 32

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Liao, Y., Zhang, H., Guo, L., Fan, B., Wang, W., Teopiz, K. M., Lui, L. M. W., Lee, Y. L., Li, L., Han, X., et al. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.08.009 · Cited by 33

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Refisch, A., Şen, Z. D., Klassert, T. E., Busch, A., Besteher, B., Danyeli, L. V., Helbing, D. L., Schulze‐Späte, U., Stallmach, A., Bauer, M. W., et al. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109568 · Cited by 33

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Xiao, X., Zhang, H., Ning, W., Yang, Z. R., Wang, Y., & Zhang, T. (2022) · Experimental Neurology · doi:10.1016/j.expneurol.2022.114060 · Cited by 29

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Kamiya, M., Sabia, H. D., Marella, J., Fava, M., Nemeroff, C. B., Umeuchi, H., Iijima, M., Chaki, S., & Nishino, I. (2020) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.05.017 · Cited by 28

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Martins‐Silva, T., Martins, R. C., Murray, J., Carvalho, A. M., Rickes, L. N., Corrêa, B. D. F., Fraga, B. B., Brum, C. B., Freitas, D. F., Meyer, F. D. T., et al. (2024) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2024.107185 · Cited by 31

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Green, C., Stolicyn, A., Harris, M. A., Shen, X., Romaniuk, L., Barbu, M. C., Hawkins, E. L., Wardlaw, J. M., Steele, J. D., Waiter, G. D., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01644-9 · Cited by 28

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Lu, X., Liu, C., Hong, L., Qian, X., Wang, C., Jia, C.-X., & Jia, F. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03063-y · Cited by 31

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Tran, A. A., Smet, M. D., Grant, G. D., Khoo, T. K., & Pountney, D. L. (2020) · Complex Psychiatry · doi:10.1159/000512657 · Cited by 29

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Straka, K., Tran, M.-L. M., Millwood, S. N., Swanson, J., & Kuhlman, K. R. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.605347 · Cited by 26

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Xie, Z., Xie, H., Peng, X., Hu, J., Chen, L., Li, X., Hu, Q., Zeng, J., & Zeng, N. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.155015 · Cited by 23

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Cătălina, G. R., Gheorman, V., Gheorman, V., & Forțofoiu, M.-C. (2025) · Healthcare · doi:10.3390/healthcare13070837 · Cited by 27

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Murphy, H. R., Gu, Y., Wu, Q., Brunner, J., Panisch, L. S., Best, M., Arnold, M. S., Duberstein, Z. T., Putzig, J., Carnahan, J. A., et al. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2022.105856 · Cited by 25

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Wu, T., Liu, R., Zhang, L., Rifky, M., Sui, W., Zhu, Q., Zhang, J., Yin, J., & Zhang, M. (2022) · Food & Function · doi:10.1039/d2fo02795j · Cited by 24

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Feng, L.-S., Wang, Y., Liu, H., Ning, B., Yu, H.-B., Li, S., Wang, Y., Zhao, M., & Ma, J. (2024) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2312222 · Cited by 22

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Stapel, B., Fraccarollo, D., Westhoff‐Bleck, M., Bauersachs, J., Lichtinghagen, R., Jahn, K., Burkert, A., Buchholz, V., Bleich, S., Frieling, H., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-11639-1 · Cited by 25

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Nasser, A., Ozenne, B., Høgsted, E. S., Jensen, P. S., & Frøkjær, V. G. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2022.105950 · Cited by 21

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Botschek, T., Hußlein, V., Peters, E. M. J., & Brosig, B. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1227153 · Cited by 26

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Barowsky, S., Jung, J.-Y., Nesbit, N., Silberstein, M. D., D, M. F. M., Loggia, M. L., Smoller, J. W., & Lee, P. H. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.687687 · Cited by 23

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Garcia, C. S., Besckow, E. M., Espíndola, C. N. D. S., Nunes, G. D., Zuge, N. P., de Azeredo, M. P., da Rocha, M. J., Júnior, L. R. C., Penteado, F., Gomes, C. S., et al. (2022) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.2c00129 · Cited by 22

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Torres‐Berrío, A., Bortolami, A., Peña, C. J., & Nestler, E. J. (2025) · Neuropsychopharmacology · doi:10.1038/s41386-025-02158-4 · Cited by 24

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Jahan, A. B., & Tanev, K. S. (2022) · Brain Injury · doi:10.1080/02699052.2022.2145362 · Cited by 22

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Rana, A. K., Sharma, S., Patial, V., & Singh, D. (2022) · Molecular Neurobiology · doi:10.1007/s12035-021-02719-w · Cited by 24

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