The DOI matches its Crossref record; 141 of the 141 references it cites were found in a registry or an index.
Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies
Open accessAbstract
Amplification of EGFR and its active mutant EGFRvIII occur frequently in GBM. While EGFR and EGFRvIII play critical roles in pathogenesis, targeted therapy with EGFR-tyrosine kinase inhibitors (TKIs) or antibodies has only shown limited efficacy in patients. Here, we discuss signaling pathways mediated by EGFR/EGFRvIII, current therapeutics, and novel strategies to target EGFR/EGFRvIII-amplified GBM.
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1 retracted
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RetractedThe 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
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The 2007 WHO Classification of Tumours of the Central Nervous System
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Comprehensive genomic characterization defines human glioblastoma genes and core pathways
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Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
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Cited by
Immunotherapy for glioblastoma: current state, challenges, and future perspectives
Liu, Y., Zhou, F., Ali, H., Lathia, J. D., & Chen, P. (2024) · Cellular & Molecular Immunology · doi:10.1038/s41423-024-01226-x · Cited by 336
Glioblastoma Multiforme: An Overview of Emerging Therapeutic Targets
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Glioblastoma Therapy: Past, Present and Future
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Metadata
- Authors
- An, Z., Aksoy, O., Zheng, T., Fan, Q.-W., & Weiss, W. A.
- Venue
- Oncogene
- Published
- 2018-01-11
- Volume
- 37
- Issue
- 12
- Pages
- 1561-1575
- ISSN
- 0950-9232 (ISSN-L)
- 1476-5594
- OpenAlex
- W2783146090
- Cited by
- 668
- References
- 141
- FWCI
- 27.60
- Type
- journal article
- Language
- en
- Open access
- green
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- An, Z., Aksoy, O., Zheng, T., Fan, Q.-W., & Weiss, W. A. (2018). Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies. Oncogene. https://doi.org/10.1038/s41388-017-0045-7
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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